Materials For Biomedical Engineering Hydrogels And Polymer Based Scaffolds

Author : Alina-Maria Holban,Alexandru Grumezescu
Publisher : Elsevier
Page : 562 pages
File Size : 45,6 Mb
Release : 2019-03-20
Category : Medical
ISBN : 9780128169025

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Materials for Biomedical Engineering: Hydrogels and Polymer-based Scaffolds by Alina-Maria Holban,Alexandru Grumezescu Pdf

Materials for Biomedical Engineering: Hydrogels and Polymer-Based Scaffolds discusses the use of a wide variety of hydrogels as bioactive scaffolds in regenerative medicine, including updates on innovative materials and their properties. Various types of currently investigated scaffolding materials and hydrogels are discussed, as is their future roles and applications, the main techniques for scaffold fabrication, and their characterization procedures. Readers will be able to use this book as a guide for the selection of the best materials for a specific application. Provides a valuable resource of recent scientific progress, highlighting the most well-known applications of hydrogels as bioactive scaffolds in regenerative medicine Includes novel opportunities and ideas for developing or improving technologies in biomaterials, and in related biomedical industries Features at least 50% of references from the last 2-3 years

Author : Rui L. Reis,Nuno M. Neves,Joao F. Mano,Manuela E. Gomes,Alexandra P. Marques,Helena S. Azevedo
Publisher : Elsevier
Page : 832 pages
File Size : 55,6 Mb
Release : 2008-08-15
Category : Technology & Engineering
ISBN : 9781845694814

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Natural-Based Polymers for Biomedical Applications by Rui L. Reis,Nuno M. Neves,Joao F. Mano,Manuela E. Gomes,Alexandra P. Marques,Helena S. Azevedo Pdf

Polymers from natural sources are particularly useful as biomaterials and in regenerative medicine, given their similarity to the extracellular matrix and other polymers in the human body. This important book reviews the wealth of research on both tried and promising new natural-based biomedical polymers, together with their applications as implantable biomaterials, controlled-release carriers or scaffolds for tissue engineering. The first part of the book reviews the sources, processing and properties of natural-based polymers for biomedical applications. Part two describes how the surfaces of polymer-based biomaterials can be modified to improve their functionality. The third part of the book discusses the use of natural-based polymers for biodegradable scaffolds and hydrogels in tissue engineering. Building on this foundation, Part four looks at the particular use of natural-gelling polymers for encapsulation, tissue engineering and regenerative medicine. The penultimate group of chapters reviews the use of natural-based polymers as delivery systems for drugs, hormones, enzymes and growth factors. The final part of the book summarises research on the key issue of biocompatibility. Natural-based polymers for biomedical applications is a standard reference for biomedical engineers, those studying and researching in this important area, and the medical community. Examines the sources, processing and properties of natural based polymers for biomedical applications Explains how the surfaces of polymer based biomaterials can be modified to improve their functionality Discusses the use of natural based polymers for hydrogels in tissue engineering, and in particular natural gelling polymers for encapsulation and regenerative medicine

Author : Rui L. Reis,Daniel Cohn
Publisher : Springer Science & Business Media
Page : 419 pages
File Size : 49,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789401003056

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Polymer Based Systems on Tissue Engineering, Replacement and Regeneration by Rui L. Reis,Daniel Cohn Pdf

Biodegradable, polymer-based systems are playing an increasingly pivotal role in tissue engineering replacement and regeneration. This type of biology-driven materials science is slated to be one of the key research areas of the 21st century. The following aspects are crucial: the development of adequate human cell culture to produce the tissues in adequate polymer scaffold materials; the development of culture technology with which human tissues can be grown ex-vivo in 3D polymer matrices; the development of material technology for producing the degradable, 3D matrices, having mechanical properties similar to natural tissue. In addressing these and similar problems, the book contains chapters on biodegradable polymers, polymeric biomaterials, surface modification for controlling cell-material interactions, scaffold design and processing, biomimetic coatings, biocompatibility evaluation, tissue engineering constructs, cell isolation, characterisation and culture, and controlled release of bioactive agents.

Author : Nithin Kundachira Subramani,Hatna Siddaramaiah
Publisher : Unknown
Page : 128 pages
File Size : 43,9 Mb
Release : 2021-03
Category : Electronic
ISBN : 1799871991

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Polymer-Based Functional Materials for Biomedical Applications by Nithin Kundachira Subramani,Hatna Siddaramaiah Pdf

Author : Naznin Sultana,Mohd Izzat Hassan,Mim Mim Lim
Publisher : Springer
Page : 61 pages
File Size : 55,6 Mb
Release : 2014-10-16
Category : Technology & Engineering
ISBN : 9783319097558

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Composite Synthetic Scaffolds for Tissue Engineering and Regenerative Medicine by Naznin Sultana,Mohd Izzat Hassan,Mim Mim Lim Pdf

This book addresses important biomaterials which are commonly used to fabricate scaffolds and it describes two major protocols employed in scaffold fabrication. Tissue engineering or regenerative medicine aims at restoring ex-novo tissues and organs whose functionality has been compromised as a consequence of diseases or traumatic events. The innovative concept underlying tissue engineering is the use of autologous cells, obtained from a biopsy of the patient. Cells are seeded on a porous scaffold which has the role of supporting and guiding cells towards the development of tissue-like structures as well as providing a platform for the delivery under controlled condition of growth factor release, etc. The successful manufacture of scaffolds for tissue engineering applications is crucial. In this book, these biomaterials are discussed. The book also covers illustrated examples, structure and properties of scaffolds, cellular interactions and drug delivery.

Author : Lacramioara Popa,Mihaela Violeta Ghica,Cristina Dinu-Pirvu
Publisher : BoD – Books on Demand
Page : 133 pages
File Size : 46,6 Mb
Release : 2019-04-10
Category : Technology & Engineering
ISBN : 9781789858754

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Hydrogels by Lacramioara Popa,Mihaela Violeta Ghica,Cristina Dinu-Pirvu Pdf

Hydrogels, as three-dimensional polymer networks, are able to retain a large amount of water in their swollen state. The biomedical application of hydrogels was initially hampered by the toxicity of cross-linking agents and the limitations of hydrogel formation under physiological conditions. However, emerging knowledge in polymer chemistry and an increased understanding of biological processes have resulted in the design of versatile materials and minimally invasive therapies.The novel but challenging properties of hydrogels are attracting the attention of researchers in the biological, medical, and pharmaceutical fields. In the last few years, new methods have been developed for the preparation of hydrophilic polymers and hydrogels, which may be used in future biomedical and drug delivery applications. Such efforts include the synthesis of self-organized nanostructures based on triblock copolymers with applications in controlled drug delivery. These hydrogels could be used as carriers for drug delivery when combined with the techniques of drug imprinting and subsequent release. Engineered protein hydrogels have many potential advantages. They are excellent biomaterials and biodegradables. Furthermore, they could encapsulate drugs and be used in injectable forms to replace surgery, to repair damaged cartilage, in regenerative medicine, or in tissue engineering. Also, they have potential applications in gene therapy, although this field is relatively new.

Author : Raphael M. Ottenbrite,Kinam Park,Teruo Okano
Publisher : Springer Science & Business Media
Page : 438 pages
File Size : 52,5 Mb
Release : 2010-09-05
Category : Technology & Engineering
ISBN : 9781441959195

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Biomedical Applications of Hydrogels Handbook by Raphael M. Ottenbrite,Kinam Park,Teruo Okano Pdf

Hydrogels are networks of polymer chains which can produce a colloidal gel containing over 99 per cent water. The superabsorbency and permeability of naturally occurring and synthetic hydrogels give this class of materials an amazing array of uses. These uses range from wound dressings and skin grafts to oxygen-permeable contact lenses to biodegradable delivery systems for drugs or pesticides and scaffolds for tissue engineering and regenerative medicine. Biomedical Applications of Hydrogels Handbook provides a comprehensive description of this diverse class of materials, covering both synthesis and properties and a broad range of research and commercial applications. The Handbook is divided into four sections: Stimuli-Sensitive Hydrogels, Hydrogels for Drug Delivery, Hydrogels for Tissue Engineering, and Hydrogels with Unique Properties. Key Features: Provides comprehensive coverage of the basic science and applications of a diverse class of materials Includes both naturally occurring and synthetic hydrogels Edited and written by world leaders in the field.

Author : naznin sultana
Publisher : Springer Science & Business Media
Page : 71 pages
File Size : 52,6 Mb
Release : 2012-12-15
Category : Technology & Engineering
ISBN : 9783642348020

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Biodegradable Polymer-Based Scaffolds for Bone Tissue Engineering by naznin sultana Pdf

This book addresses the principles, methods and applications of biodegradable polymer based scaffolds for bone tissue engineering. The general principle of bone tissue engineering is reviewed and the traditional and novel scaffolding materials, their properties and scaffold fabrication techniques are explored. By acting as temporary synthetic extracellular matrices for cell accommodation, proliferation, and differentiation, scaffolds play a pivotal role in tissue engineering. This book does not only provide the comprehensive summary of the current trends in scaffolding design but also presents the new trends and directions for scaffold development for the ever expanding tissue engineering applications.

Author : Sangamesh G. Kum bar,Cato Laurencin,Meng Deng
Publisher : Newnes
Page : 421 pages
File Size : 53,8 Mb
Release : 2014-01-21
Category : Technology & Engineering
ISBN : 9780123972903

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Natural and Synthetic Biomedical Polymers by Sangamesh G. Kum bar,Cato Laurencin,Meng Deng Pdf

Polymers are important and attractive biomaterials for researchers and clinical applications due to the ease of tailoring their chemical, physical and biological properties for target devices. Due to this versatility they are rapidly replacing other classes of biomaterials such as ceramics or metals. As a result, the demand for biomedical polymers has grown exponentially and supports a diverse and highly monetized research community. Currently worth $1.2bn in 2009 (up from $650m in 2000), biomedical polymers are expected to achieve a CAGR of 9.8% until 2015, supporting a current research community of approximately 28,000+. Summarizing the main advances in biopolymer development of the last decades, this work systematically covers both the physical science and biomedical engineering of the multidisciplinary field. Coverage extends across synthesis, characterization, design consideration and biomedical applications. The work supports scientists researching the formulation of novel polymers with desirable physical, chemical, biological, biomechanical and degradation properties for specific targeted biomedical applications. Combines chemistry, biology and engineering for expert and appropriate integration of design and engineering of polymeric biomaterials Physical, chemical, biological, biomechanical and degradation properties alongside currently deployed clinical applications of specific biomaterials aids use as single source reference on field. 15+ case studies provides in-depth analysis of currently used polymeric biomaterials, aiding design considerations for the future

Author : Vijay Kumar Thakur,Manju Kumari Thakur
Publisher : Springer
Page : 470 pages
File Size : 48,8 Mb
Release : 2018-08-28
Category : Technology & Engineering
ISBN : 9789811060779

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Hydrogels by Vijay Kumar Thakur,Manju Kumari Thakur Pdf

This book discusses recent advances in hydrogels, including their generation and applications and presents a compendium of fundamental concepts. It highlights the most important hydrogel materials, including physical hydrogels, chemical hydrogels, and nanohydrogels and explores the development of hydrogel-based novel materials that respond to external stimuli, such as temperature, pressure, pH, light, biochemicals or magnetism, which represent a new class of intelligent materials. With their multiple cooperative functions, hydrogel-based materials exhibit different potential applications ranging from biomedical engineering to water purification systems. This book covers key topics including superabsorbent polymer hydrogel; intelligent hydrogels for drug delivery; hydrogels from catechol-conjugated materials; nanomaterials loaded hydrogel; electrospinning of hydrogels; biopolymers-based hydrogels; injectable hydrogels; interpenetrating-polymer-network hydrogels: radiation- and sonochemical synthesis of micro/nano/macroscopic hydrogels; DNA-based hydrogels; and multifunctional applications of hydrogels. It will prove a valuable resource for researchers working in industry and academia alike.

Author : M. Molly S. Shoichet,Jay Abel Hubbell
Publisher : VSP
Page : 460 pages
File Size : 51,5 Mb
Release : 1998-01-01
Category : Technology & Engineering
ISBN : 9067642894

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Polymers for Tissue Engineering by M. Molly S. Shoichet,Jay Abel Hubbell Pdf

The articles included in this text highlight the important advances in polymer science that impact tissue engineering. The breadth of polymer science is well represented with the relevance of both polymer chemistry and morphology emphasized in terms of cell and tissue response.

Author : Claudio Migliaresi,Antonella Motta
Publisher : CRC Press
Page : 701 pages
File Size : 50,6 Mb
Release : 2014-06-10
Category : Medical
ISBN : 9789814463201

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Scaffolds for Tissue Engineering by Claudio Migliaresi,Antonella Motta Pdf

Scaffolds for tissue engineering are devices that exploit specific and complex physical and biological functions, in vitro or in vivo, and communicate through biochemical and physical signals with cells and, when implanted, with the body environment. Scaffolds are produced mainly with synthetic materials, and their fabrication technologies are derived from already well-established industrial processes, with some new specific technologies having been developed in the last years to address required complexities. Often, a generalist approach is followed for the translation of materials and technologies designed for other applications, without considering the specific role of scaffolds from a physical and biological point of view. The book illustrates scaffold design principles, with particular relevance to the biological requirements needed to control and drive the biological cross talk, and reviews materials and fabrication and validation methods.

Author : Alina-Maria Holban,Alexandru Grumezescu
Publisher : Elsevier
Page : 534 pages
File Size : 49,6 Mb
Release : 2019-03-20
Category : Medical
ISBN : 9780128169148

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Materials for Biomedical Engineering: Nanomaterials-based Drug Delivery by Alina-Maria Holban,Alexandru Grumezescu Pdf

Materials for Biomedical Engineering: Nanomaterials-Based Drug Delivery highlights the progress made in the field of nanostructures bioactive materials and their impact on efficient drug delivery towards personalized medicine. Drug delivery is a well investigated and challenging bio-medical field, with promising perspectives in medicine and engineering. This book brings together the latest research findings regarding nanostructured materials and their potential in designing highly efficient and personalized drug delivery systems. Provides a valuable resource of recent scientific progress, highlighting the most well-known applications of nanostructures in drug delivery systems Includes novel opportunities and ideas for developing or improving technologies in composites by companies, biomedical industries, and in related sectors Features at least 50% of references from the last 2-3 years

Author : Vijay Chaudhary,Sumit Gupta,Pallav Gupta,Partha Pratim Das
Publisher : CRC Press
Page : 217 pages
File Size : 53,8 Mb
Release : 2023-08-31
Category : Technology & Engineering
ISBN : 9781000952254

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Assessment of Polymeric Materials for Biomedical Applications by Vijay Chaudhary,Sumit Gupta,Pallav Gupta,Partha Pratim Das Pdf

Addresses assessment of polymeric materials in biomedical sciences including classification, properties, and development of polymeric implants Covers various topics in the field of tissue regeneration Discusses the biocompatibility, toxicity, and biodegradation of polymeric materials Explores wide scale characterization to study the effect of inclusion size on mechanical properties of polymeric materials Reviews limitations and future directions on polymeric material with emphasis on biocompatibility

Author : Alexandru Grumezescu,Alina-Maria Holban
Publisher : Elsevier
Page : 616 pages
File Size : 41,5 Mb
Release : 2019-06-18
Category : Medical
ISBN : 9780128184349

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Materials for Biomedical Engineering: Organic Micro and Nanostructures by Alexandru Grumezescu,Alina-Maria Holban Pdf

Materials for Biomedical Engineering: Organic Micro- and Nanostructures provides an updated perspective on recent research regarding the use of organic particles in biomedical applications. The different types of organic micro- and nanostructures are discussed, as are innovative applications and new synthesis methods. As biomedical applications of organic micro- and nanostructures are very diverse and their impact on modern and future therapy, diagnosis and prophylaxis of diseases is huge, this book presents a timely resource on the topic. Users will find the latest information on cancer and gene therapy, diagnosis, drug delivery, green synthesis of nano- and microparticles, and much more. Provides knowledge of the range of organic micro- and nanostructures available, enabling the reader to make optimal materials selection decisions Presents detailed information on current and proposed applications of the latest biomedical materials Places a strong emphasis on the characterization, production and use of organic nanoparticles in biomedicine, such as gene therapy, DNA interaction and cancer management