Mathematics Of Dna Structure Function And Interactions

Author : Craig John Benham,Stephen Harvey,Wilma K. Olson,De Witt Sumners,David Swigon
Publisher : Springer Science & Business Media
Page : 359 pages
File Size : 53,6 Mb
Release : 2010-04-29
Category : Medical
ISBN : 9781441906717

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Mathematics of DNA Structure, Function and Interactions by Craig John Benham,Stephen Harvey,Wilma K. Olson,De Witt Sumners,David Swigon Pdf

Propelled by the success of the sequencing of the human and many related genomes, molecular and cellular biology has delivered significant scientific breakthroughs. Mathematics (broadly defined) continues to play a major role in this effort, helping to discover the secrets of life by working collaboratively with bench biologists, chemists and physicists. Because of its outstanding record of interdisciplinary research and training, the IMA was an ideal venue for the 2007-2008 IMA thematic year on Mathematics of Molecular and Cellular Biology. The kickoff event for this thematic year was a tutorial on Mathematics of Nucleic Acids, followed by the workshop Mathematics of Molecular and Cellular Biology, held September 15--21 at the IMA. This volume is dedicated to the memory of Nicholas R. Cozzarelli, a dynamic leader who fostered research and training at the interface between mathematics and molecular biology. It contains a personal remembrance of Nick Cozzarelli, plus 15 papers contributed by workshop speakers. The papers give an overview of state-of-the-art mathematical approaches to the understanding of DNA structure and function, and the interaction of DNA with proteins that mediate vital life processes.

Author : Richard R. Sinden
Publisher : Elsevier
Page : 398 pages
File Size : 53,7 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780080571737

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DNA Structure and Function by Richard R. Sinden Pdf

DNA Structure and Function, a timely and comprehensive resource, is intended for any student or scientist interested in DNA structure and its biological implications. The book provides a simple yet comprehensive introduction to nearly all aspects of DNA structure. It also explains current ideas on the biological significance of classic and alternative DNA conformations. Suitable for graduate courses on DNA structure and nucleic acids, the text is also excellent supplemental reading for courses in general biochemistry, molecular biology, and genetics. Explains basic DNA Structure and function clearly and simply Contains up-to-date coverage of cruciforms, Z-DNA, triplex DNA, and other DNA conformations Discusses DNA-protein interactions, chromosomal organization, and biological implications of structure Highlights key experiments and ideas within boxed sections Illustrated with 150 diagrams and figures that convey structural and experimental concepts

Author : Marcio Santos Rocha
Publisher : Elsevier
Page : 268 pages
File Size : 55,7 Mb
Release : 2023-03-01
Category : Medical
ISBN : 9780323993852

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DNA Interactions with Drugs and Other Small Ligands by Marcio Santos Rocha Pdf

DNA Interactions With Drugs and Other Small Ligands: Single Molecule Approaches and Techniques provides the reader with all the main information, a "state-of-the-art" of sorts and an overall review of the field. There is no other book currently available that covers all these subjects together. On the contrary, the different subjects that are developed in this book are currently scattered in journal articles and other books. Presents a review of the fundamental knowledge, techniques and relevant information surrounding the field of DNA interactions with drugs and other ligands Provides a resource like no other book available Includes valuable information from the author who is a highly experienced researcher in the field

Author : Yakov M Tseytlin
Publisher : Academic Press
Page : 316 pages
File Size : 41,7 Mb
Release : 2016-07-29
Category : Science
ISBN : 9780128020364

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Advanced Mechanical Models of DNA Elasticity by Yakov M Tseytlin Pdf

Advanced Mechanical Models of DNA Elasticity includes coverage on 17 different DNA models and the role of elasticity in biological functions with extensive references. The novel advanced helicoidal model described reflects the direct connection between the molecule helix structure and its specific properties, including nonlinear features and transitions. It provides an introduction to the state of the field of DNA mechanics, known and widely used models with their short analysis, as well as coverage on experimental methods and data, the influence of electrical, magnetic, ionic conditions on the persistence length, and dynamics with viscosity influence. It then addresses the need to understand the nature of the non-linear overstretching transition of DNA under force and why DNA has a negative twist-stretch coupling. Includes coverage of 17 contemporary models of DNA mechanics with analysis Provides comparison of DNA and RNA mechanical features Covers advances in experimental techniques including AFM, X-ray, and optical tweezers Contains extensive references for further reading

Author : Alyson Deines,Daniela Ferrero,Erica Graham,Mee Seong Im,Carrie Manore,Candice Price
Publisher : Springer
Page : 270 pages
File Size : 45,8 Mb
Release : 2018-10-31
Category : Mathematics
ISBN : 9783319986845

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Advances in the Mathematical Sciences by Alyson Deines,Daniela Ferrero,Erica Graham,Mee Seong Im,Carrie Manore,Candice Price Pdf

Featuring research from the 2017 research symposium of the Association for Women in Mathematics, this volume presents recent findings in pure mathematics and a range of advances and novel applications in fields such as engineering, biology, and medicine. Featured topics include geometric group theory, generalized iterated wreath products of cyclic groups and symmetric groups, Conway-Coxeter friezes and mutation, and classroom experiments in teaching collegiate mathematics. A review of DNA topology and a computational study of learning-induced sequence reactivation during sharp-wave ripples are also included in this volume. Numerous illustrations and tables convey key results throughout the book. This volume highlights research from women working in academia, industry, and government. It is a helpful resource for researchers and graduate students interested in an overview of the latest research in mathematics.

Author : Nataša Jonoska,Masahico Saito
Publisher : Springer Science & Business Media
Page : 524 pages
File Size : 53,5 Mb
Release : 2013-12-23
Category : Computers
ISBN : 9783642401930

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Discrete and Topological Models in Molecular Biology by Nataša Jonoska,Masahico Saito Pdf

Theoretical tools and insights from discrete mathematics, theoretical computer science, and topology now play essential roles in our understanding of vital biomolecular processes. The related methods are now employed in various fields of mathematical biology as instruments to "zoom in" on processes at a molecular level. This book contains expository chapters on how contemporary models from discrete mathematics – in domains such as algebra, combinatorics, and graph and knot theories – can provide perspective on biomolecular problems ranging from data analysis, molecular and gene arrangements and structures, and knotted DNA embeddings via spatial graph models to the dynamics and kinetics of molecular interactions. The contributing authors are among the leading scientists in this field and the book is a reference for researchers in mathematics and theoretical computer science who are engaged with modeling molecular and biological phenomena using discrete methods. It may also serve as a guide and supplement for graduate courses in mathematical biology or bioinformatics, introducing nontraditional aspects of mathematical biology.

Author : Priti Kumar Roy,Xianbing Cao,Xue-Zhi Li,Pratulananda Das,Satya Deo
Publisher : Springer Nature
Page : 518 pages
File Size : 48,5 Mb
Release : 2020-03-10
Category : Mathematics
ISBN : 9789811504228

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Mathematical Analysis and Applications in Modeling by Priti Kumar Roy,Xianbing Cao,Xue-Zhi Li,Pratulananda Das,Satya Deo Pdf

This book collects select papers presented at the “International Conference on Mathematical Analysis and Application in Modeling,” held at Jadavpur University, Kolkata, India, on 9–12 January 2018. It discusses new results in cutting-edge areas of several branches of mathematics and applications, including analysis, topology, dynamical systems (nonlinear, topological), mathematical modeling, optimization and mathematical biology. The conference has emerged as a powerful forum, bringing together leading academics, industry experts and researchers, and offering them a venue to discuss, interact and collaborate in order to stimulate the advancement of mathematics and its industrial applications.

Author : Michael Chandler,Martin Gellert,Alan M. Lambowitz,Phoebe A. Rice,Suzanne B. Sandmeyer
Publisher : John Wiley & Sons
Page : 1321 pages
File Size : 41,7 Mb
Release : 2020-07-24
Category : Science
ISBN : 9781555819217

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Mobile DNA III by Michael Chandler,Martin Gellert,Alan M. Lambowitz,Phoebe A. Rice,Suzanne B. Sandmeyer Pdf

An exploration of the raw power of genetic material to refashion itself to any purpose... Virtually all organisms contain multiple mobile DNAs that can move from place to place, and in some organisms, mobile DNA elements make up a significant portion of the genome. Mobile DNA III provides a comprehensive review of recent research, including findings suggesting the important role that mobile elements play in genome evolution and stability. Editor-in-Chief Nancy L. Craig assembled a team of multidisciplinary experts to develop this cutting-edge resource that covers the specific molecular mechanisms involved in recombination, including a detailed structural analysis of the enzymes responsible presents a detailed account of the many different recombination systems that can rearrange genomes examines the tremendous impact of mobile DNA in virtually all organisms Mobile DNA III is valuable as an in-depth supplemental reading for upper level life sciences students and as a reference for investigators exploring new biological systems. Biomedical researchers will find documentation of recent advances in understanding immune-antigen conflict between host and pathogen. It introduces biotechnicians to amazing tools for in vivo control of designer DNAs. It allows specialists to pick and choose advanced reviews of specific elements and to be drawn in by unexpected parallels and contrasts among the elements in diverse organisms. Mobile DNA III provides the most lucid reviews of these complex topics available anywhere.

Author : Michal Křížek,Lawrence Somer,Alena Šolcová
Publisher : Springer Nature
Page : 342 pages
File Size : 50,5 Mb
Release : 2021-09-21
Category : Mathematics
ISBN : 9783030838997

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From Great Discoveries in Number Theory to Applications by Michal Křížek,Lawrence Somer,Alena Šolcová Pdf

This book provides an overview of many interesting properties of natural numbers, demonstrating their applications in areas such as cryptography, geometry, astronomy, mechanics, computer science, and recreational mathematics. In particular, it presents the main ideas of error-detecting and error-correcting codes, digital signatures, hashing functions, generators of pseudorandom numbers, and the RSA method based on large prime numbers. A diverse array of topics is covered, from the properties and applications of prime numbers, some surprising connections between number theory and graph theory, pseudoprimes, Fibonacci and Lucas numbers, and the construction of Magic and Latin squares, to the mathematics behind Prague’s astronomical clock. Introducing a general mathematical audience to some of the basic ideas and algebraic methods connected with various types of natural numbers, the book will provide invaluable reading for amateurs and professionals alike.

Author : Stanley Maloy,Kelly Hughes
Publisher : Academic Press
Page : 4360 pages
File Size : 53,7 Mb
Release : 2013-03-03
Category : Science
ISBN : 9780080961569

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Brenner's Encyclopedia of Genetics by Stanley Maloy,Kelly Hughes Pdf

The explosion of the field of genetics over the last decade, with the new technologies that have stimulated research, suggests that a new sort of reference work is needed to keep pace with such a fast-moving and interdisciplinary field. Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set, builds on the foundation of the first edition by addressing many of the key subfields of genetics that were just in their infancy when the first edition was published. The currency and accessibility of this foundational content will be unrivalled, making this work useful for scientists and non-scientists alike. Featuring relatively short entries on genetics topics written by experts in that topic, Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set provides an effective way to quickly learn about any aspect of genetics, from Abortive Transduction to Zygotes. Adding to its utility, the work provides short entries that briefly define key terms, and a guide to additional reading and relevant websites for further study. Many of the entries include figures to explain difficult concepts. Key terms in related areas such as biochemistry, cell, and molecular biology are also included, and there are entries that describe historical figures in genetics, providing insights into their careers and discoveries. This 7-volume set represents a 25% expansion from the first edition, with over 1600 articles encompassing this burgeoning field Thoroughly up-to-date, with many new topics and subfields covered that were in their infancy or not inexistence at the time of the first edition. Timely coverage of emergent areas such as epigenetics, personalized genomic medicine, pharmacogenetics, and genetic enhancement technologies Interdisciplinary and global in its outlook, as befits the field of genetics Brief articles, written by experts in the field, which not only discuss, define, and explain key elements of the field, but also provide definition of key terms, suggestions for further reading, and biographical sketches of the key people in the history of genetics

Author : Wen-Yuan Qiu
Publisher : Unknown
Page : 128 pages
File Size : 52,7 Mb
Release : 2010
Category : Medical
ISBN : 1616685891

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The Chemistry and Mathematics of DNA Polyhedra by Wen-Yuan Qiu Pdf

Author : Gilbert Chauvet
Publisher : World Scientific
Page : 300 pages
File Size : 46,7 Mb
Release : 2004-10-01
Category : Science
ISBN : 9789814482875

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The Mathematical Nature of the Living World by Gilbert Chauvet Pdf

' The topic of the book — a theory of functional biology that incorporates the fundamental principles underlying the functioning of living organisms — is clearly appropriate as we celebrate the 50th anniversary of the discovery by Watson and Crick of the structure of the DNA molecule. 'The Mathematical Nature of the Living World: The Power of Integration' is here to remind us that the world of biology is anchored in the world of mathematics and physics, and that, to understand the living world, we need to incorporate the laws of the nonliving matter. In particular, an important emphasis of the book concerns the relationships between structure and function, a point so well illustrated by the work of Watson and Crick. A nice aspect of Chauvet's book is that he does place his work and his approach in a general framework and historical background of the work performed by pioneers in a variety of fields ranging from physics to biology. As such, the book should be of general interest to a wide range of readers, from college students interested in integrating biology with physics and mathematics, to general readers curious to know more about the differences between the living world and the nonliving matter, to professional scientists and teachers concerned with more specific questions regarding relationships between structure and function in biology. Contents:Physical and Biological InteractionsThe Functional Organization of Living OrganismsThe Integration of Physiological FunctionsStructural and Functional Organizations of Living OrganismsPhysiological Constraints of Biological DevelopmentThe Role of Space in Functional Biological Organization Readership: Biomathematicians, biomedical scientists, computer scientists, physiologists and philosophers. Keywords:Integration;Theory;Epistemology;Biological Systems;Hierarchy;Functional Organization;Organizational PrinciplesKey Features:Is an extension to biology of principles commonly used in physicsIs based on the concept of functional interaction developed by the author over the last 20 yearsDevelops the concept of hierarchy between levels of organizations, and presents various illustrations to document his argumentIs illustrated from suggestive examples selected from various fields of biologyIs an introduction to the field of integrative biology, a field which is taking increasing importance in a world overloaded with data and where theory and basic concepts are underrepresentedReviews:“This is a good companion to Chauvet's Theoretical Systems in Biology: Hierarchical and Functional Integration … Very thorough reference list.”Choice “This text, unveiling non-traditional applications of mathematics in life sciences, is written nicely and the exposition is easy to follow because mathematical and physical details are explained in a manner which makes them accessible to a wide audience of biologists, whereas the biological ideas behind the mathematical and physical foundations can be quite well understood by mathematicians and physicists. Developing very interesting, seminal ideas regarding the evolution of the living world and promoting enthusiastically a novel approach to theoretical physiology that exploits quite high levels of mathematical abstraction, the author makes a welcome contribution to the contemporary literature in the field.”Zentralblatt MATH '

Author : David M. J. Lilley
Publisher : Unknown
Page : 0 pages
File Size : 52,9 Mb
Release : 2024-06-03
Category : DNA-protein interactions
ISBN : 1383048738

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DNA-protein by David M. J. Lilley Pdf

Many processes in the genetic life of the cell require a specific interaction between proteins and DNA. This text explores the importance of DNA structure in the interactions between proteins and DNA in order to generate a new perspective on DNA-protein.

Author : Daskalaki, Andriani
Publisher : IGI Global
Page : 982 pages
File Size : 49,8 Mb
Release : 2008-11-30
Category : Technology & Engineering
ISBN : 9781605660776

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Handbook of Research on Systems Biology Applications in Medicine by Daskalaki, Andriani Pdf

"This book highlights the use of systems approaches including genomic, cellular, proteomic, metabolomic, bioinformatics, molecular, and biochemical, to address fundamental questions in complex diseases like cancer diabetes but also in ageing"--Provided by publisher.

Author : Sarfaraz K. Niazi,Justin L. Brown
Publisher : CRC Press
Page : 746 pages
File Size : 48,9 Mb
Release : 2017-07-27
Category : Medical
ISBN : 9781466585744

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Fundamentals of Modern Bioprocessing by Sarfaraz K. Niazi,Justin L. Brown Pdf

Biological drug and vaccine manufacturing has quickly become one of the highest-value fields of bioprocess engineering, and many bioprocess engineers are now finding job opportunities that have traditionally gone to chemical engineers. Fundamentals of Modern Bioprocessing addresses this growing demand. Written by experts well-established in the field, this book connects the principles and applications of bioprocessing engineering to healthcare product manufacturing and expands on areas of opportunity for qualified bioprocess engineers and students. The book is divided into two sections: the first half centers on the engineering fundamentals of bioprocessing; while the second half serves as a handbook offering advice and practical applications. Focused on the fundamental principles at the core of this discipline, this work outlines every facet of design, component selection, and regulatory concerns. It discusses the purpose of bioprocessing (to produce products suitable for human use), describes the manufacturing technologies related to bioprocessing, and explores the rapid expansion of bioprocess engineering applications relevant to health care product manufacturing. It also considers the future of bioprocessing—the use of disposable components (which is the fastest growing area in the field of bioprocessing) to replace traditional stainless steel. In addition, this text: Discusses the many types of genetically modified organisms Outlines laboratory techniques Includes the most recent developments Serves as a reference and contains an extensive bibliography Emphasizes biological manufacturing using recombinant processing, which begins with creating a genetically modified organism using recombinant techniques Fundamentals of Modern Bioprocessing outlines both the principles and applications of bioprocessing engineering related to healthcare product manufacturing. It lays out the basic concepts, definitions, methods and applications of bioprocessing. A single volume comprehensive reference developed to meet the needs of students with a bioprocessing background; it can also be used as a source for professionals in the field.