Maturation Phenomenon In Cerebral Ischemia Iv

Author : N.G. . Bazan,U. Ito,V.L. Marcheselli,T. Kuroiwa,I. Klatzo
Publisher : Springer Science & Business Media
Page : 423 pages
File Size : 50,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642594465

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Maturation Phenomenon in Cerebral Ischemia IV by N.G. . Bazan,U. Ito,V.L. Marcheselli,T. Kuroiwa,I. Klatzo Pdf

The maturation phenomenon, first described by Ito et al. in 1975, refers to postischemic changes that develop hours or days after an ischemic insult. The delayed neuronal death of CA1 pyramidal cells of the hippocampus is a classic example. The report of the phenomenon boosted research in the field, as it became evident that ischemic damage is not a sudden event, but a process potentially susceptible to therapeutic intervention. Since then a growing number of studies have improved our knowledge on mechanisms of cell death and recovery. This volume contains the presentations of the 4th international symposium, held in New Orleans in October/November 1999, grouped in sections covering apoptosis and/or necrosis, neuronal recovery vs. death, and protection against infarction. It outlines the present status of investigations and provides further stimulation for research in this field.

Author : Umeo Ito,Cesare Fieschi,Francesco Orzi,Toshihiko Kuroiwa,Igor Klatzo
Publisher : Springer Science & Business Media
Page : 325 pages
File Size : 40,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642586026

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Maturation Phenomenon in Cerebral Ischemia III by Umeo Ito,Cesare Fieschi,Francesco Orzi,Toshihiko Kuroiwa,Igor Klatzo Pdf

The Maturation Phenomenon, described by Ito et al. in 1975 [3) on the basis of his to logical observations in the hippocampus as well as other portions of the cerebral hemisphere, refers to the hours or days of delay in the development of pathological changes in various parameters of ischemic injury following the restoration of blood flow to the ischemic brain. There is a direct relationship between the intensity of ischemic insult and the speed and rate of maturation of ischemic injury, a lesser intensity being associated with slower and less severe development of the lesions. The delayed neuronal death of CAl pyramidal cells of the hippocampus [8) is a classic example. In the cerebral cortex, with increasing intensity of the ischemic insult, the maturation phenomenon of ischemic injuries intensifies, seamlessly, from less exten sive to more extensive disseminated selective neuronal necrosis (DSNN), and then further to cerebral infarction upon reaching a critical threshold [1,2,4,6,7). We also have found that following ischemic insults just under the threshold level required to induce infarction, only disseminated selective neuronal necrosis (DSNN) progresses, while following ischemic insults at the threshold level, initially only DSNN develops, followed by the evolution of a gradually enlarging infarcted focus [5, 7). The reporting of this phenomenon boosted research in the field, as it became evi dent that ischemic damage is not a sudden event, but a process potentially susceptible to therapeutic intervention.

Author : Umeo Ito,Takaaki Kirino,Toshihiko Kuroiwa,Igor Klatzo
Publisher : Springer Science & Business Media
Page : 331 pages
File Size : 54,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642605468

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Maturation Phenomenon in Cerebral Ischemia II by Umeo Ito,Takaaki Kirino,Toshihiko Kuroiwa,Igor Klatzo Pdf

Many nerve cells of the brain which are not killed outright may suffer delayed death or recovery after ischemic insult. This fact has led to the concept of "maturation phenomenon" of neuronal injuries. Since the 1st International Symposium on Maturation Phenomenon in 1990, new developments, particularly in molecular biology, have been rapidly bringing new information about molecular nature and mechanisms of cell death. This book contains the presentations of the 2nd International Symposium held in Tokyo in April 1996. The latest developments in maturation phenomenon and the present status of investigation are described and further stimulation of research in this field is provided.

Author : U. Ito,T. Kirino,T. Kuroiwa,I. Klatzo
Publisher : Springer Science & Business Media
Page : 208 pages
File Size : 45,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642771347

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Maturation Phenomenon in Cerebral Ischemia by U. Ito,T. Kirino,T. Kuroiwa,I. Klatzo Pdf

It has been well recognized that following an ischemic insult many nerve cells of the brain are not killed outright, but may suffer a "delayed neuronal death" or even recover. This led to the concept of "maturation phenomenon" with its main implication that the maturation of ischemic lesions may provide a "window of opportunity" i.e. a period of time when the injury to neuronal elements is still reversible, and during which an application of proper therapeutic measures might be successful. The symposium on Maturation Phenomenon in Cerebral Ischemia was the first international meeting focussed primarily on this subject and the resulting publication contains presentations and discussionsby prominent researchers engaged in this field. This book should stimulate further research on potential of brain tissue for recovery, and particularly with regard to a functional recovery of neurons suffering from chronic ischemic injury.

Author : Anonim
Publisher : Unknown
Page : 0 pages
File Size : 46,9 Mb
Release : 2001
Category : Electronic
ISBN : OCLC:946696163

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Maturation Phenomenon in Cerebral Ischemia IV. by Anonim Pdf

Young animals were previously shown to be more resistant to ischemia than were adult animals. This difference was attributed to maturation/function of gonads and/or neurons. This study evaluated the existence of age-related changes in transcriptional expression of HSC70, HSP72, and c-fos mRNA intransient global ischemia, and their possible relationship to neuronal cell survival in CA1 hippocampus. The results indicated that ischemic response in young animals compared with that in adult animals showed: (1) more rapid and /or prolonged expression of HSC70, HSP72, and c-fos mRNAs; (2) a marked induction of HSP72 protein; and (3) enhanced pyramidal cell survival. The observed endogenous 'tolerance' of CA1 neurons in young gerbils to ischemia/reperfusion injury may be related to the expression of HSC70, HSP72 and c-fos.

Author : A.M. Buchan,U. Ito,F. Colbourne,T. Kuroiwa,I. Klatzo
Publisher : Springer
Page : 390 pages
File Size : 42,5 Mb
Release : 2003-12-08
Category : Medical
ISBN : CHI:65761380

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Maturation Phenomenon in Cerebral Ischemia V by A.M. Buchan,U. Ito,F. Colbourne,T. Kuroiwa,I. Klatzo Pdf

Fifth International Workshop April 28-May 1, 2002 Banff, Alberta, Canada

Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 49,6 Mb
Release : 1997
Category : Electronic
ISBN : OCLC:67910354

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Maturation Phenomenon in Cerebral Ischemia by Anonim Pdf

Author : Anonim
Publisher : Unknown
Page : 362 pages
File Size : 46,8 Mb
Release : 2004
Category : Apoptosis
ISBN : OCLC:760941094

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Maturation Phenomenon in Cerebral Ischemia V by Anonim Pdf

Author : Umeo Ito
Publisher : Springer Verlag
Page : 208 pages
File Size : 55,7 Mb
Release : 1992
Category : Medical
ISBN : 0387548718

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Maturation Phenomenon in Cerebral Ischemia by Umeo Ito Pdf

Author : T. Kuroiwa,A. Baethmann,Z. Czernicki,J.T. Hoff,U. Ito,Y. Katayama,A. Marmarou,D. Mendelow,H.-J. Reulen
Publisher : Springer Science & Business Media
Page : 612 pages
File Size : 51,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783709106518

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Brain Edema XII by T. Kuroiwa,A. Baethmann,Z. Czernicki,J.T. Hoff,U. Ito,Y. Katayama,A. Marmarou,D. Mendelow,H.-J. Reulen Pdf

Brain edema is a simple phenomenon – an abnormal increase of brain tissue volume by the increase of brain tissue water content. However the etiology is not simple and relating to a wide variety of neurological disorders including ischemia, trauma, tumor, hemorrhage and hydrocephalus. It is still a major cause of death in the neurological/neurosurgical ward. This volume is an up-to-date report on progress in brain edema research, diagnosis and treatment, including papers presented at the 12th International Symposium on Brain Edema and Brain Tissue Injury in 2002. Major topics include molecular biology and blood-brain barrier disorders, ischemic and traumatic brain edema, imaging and diagnosis of brain edema, treatment and radiation effect. Various papers in the rapidly growing fields of neuroimaging and molecular medicine are also included.

Author : R. Gilberto González,Joshua A. Hirsch,Michael H. Lev,Pamela W. Schaefer,Lee H. Schwamm
Publisher : Springer Science & Business Media
Page : 299 pages
File Size : 54,8 Mb
Release : 2010-10-05
Category : Medical
ISBN : 9783642127519

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Acute Ischemic Stroke by R. Gilberto González,Joshua A. Hirsch,Michael H. Lev,Pamela W. Schaefer,Lee H. Schwamm Pdf

This updated second edition of Acute Ischemic Stroke: Imaging and Intervention provides a comprehensive account of the state of the art in the diagnosis and treatment of acute ischemic stroke. The basic format of the first edition has been retained, with sections on fundamentals such as pathophysiology and causes, imaging techniques and interventions. However, each chapter has been revised to reflect the important recent progress in advanced neuroimaging and the use of interventional tools. In addition, a new chapter is included on the classification instruments for ischemic stroke and their use in predicting outcomes and therapeutic triage. All of the authors are internationally recognized experts and members of the interdisciplinary stroke team at the Massachusetts General Hospital and Harvard Medical School. The text is supported by numerous informative illustrations, and ease of reference is ensured through the inclusion of suitable tables. This book will serve as a unique source of up-to-date information for neurologists, emergency physicians, radiologists and other health care providers who care for the patient with acute ischemic stroke.

Author : Michael P. Barnes,Bruce H. Dobkin,Julien Bogousslavsky
Publisher : Cambridge University Press
Page : 672 pages
File Size : 55,8 Mb
Release : 2005-03-10
Category : Medical
ISBN : 052182236X

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Recovery After Stroke by Michael P. Barnes,Bruce H. Dobkin,Julien Bogousslavsky Pdf

Covering neuroscience and rehabilitation strategies, an essential handbook and reference for multidisciplinary stroke rehabilitation teams.

Author : David Maguire,Duane F. Bruley
Publisher : Springer Science & Business Media
Page : 217 pages
File Size : 46,8 Mb
Release : 2007-08-11
Category : Science
ISBN : 9780387717647

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Oxygen Transport to Tissue XXVIII by David Maguire,Duane F. Bruley Pdf

This multidisciplinary book covers all aspects of oxygen delivery to tissue, including blood flow and its regulation as well as oxygen metabolism as discussed at the 33rd Annual Meeting of the International Society on Oxygen Transport to Tissue (ISOTT) held in Australia in 2005. Special attention is paid to methods of oxygen measurement in living tissue and the application of these technologies to understanding the physiological and biochemical basis for pathology related to tissue oxygenation.

Author : Y. Fukuuchi,M. Tomita,A. Koto
Publisher : Springer Science & Business Media
Page : 502 pages
File Size : 42,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9784431678991

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Ischemic Blood Flow in the Brain by Y. Fukuuchi,M. Tomita,A. Koto Pdf

Because stroke is essentially a disease of the vessels and blood flow, the most fundamental aspects of ischemic blood flow in the brain are under investigation by researchers. Their work was the focus of the sixth in the series of Keio University International Symposia for Life Sciences and Medicine, held in Tokyo in 1999. Selected here are 55 papers from the symposium, covering the buffy coat (glycocalyx) of endothelial cells, the blood-brain barrier and permeability, gene expression, vascular reactivity, dysregulation, inflammatory deterioration, cortical spreading depression, edema, microvascular derangement, and pathology, in ten major sections. The book includes the thought-provoking discussions that followed the presentations, thus providing an invaluable source of up-to-date information not only for researchers investigating microcirculation but also for clinicians implementing the most effective treatment for stroke patients.

Author : Janet A. Courtney
Publisher : Routledge
Page : 236 pages
File Size : 40,6 Mb
Release : 2020-03-12
Category : Psychology
ISBN : 9780429841637

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Infant Play Therapy by Janet A. Courtney Pdf

Infant Play Therapy is a groundbreaking resource for practitioners interested in the varied play therapy theories, models, and programs available for the unique developmental needs of infants and children under the age of three. The impressive list of expert contributors in the fields of play therapy and infant mental health cover a wide range of early intervention play-based models and topics. Chapters explore areas including: neurobiology, developmental trauma, parent-infant attachment relationships, neurosensory play, affective touch, grief and loss, perinatal depression, adoption, autism, domestic violence, sociocultural factors, and more. Chapter case studies highlight leading approaches and offer techniques to provide a comprehensive understanding of both play therapy and the ways we understand and recognize the therapeutic role of play with infants. In these pages professionals and students alike will find valuable clinical resources to bring healing to family systems with young children.