Mechanism Experiment Disease

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Mechanism, Experiment, Disease

Author : Domenico Bertoloni Meli
Publisher : JHU Press
Page : 472 pages
File Size : 42,5 Mb
Release : 2011-05-02
Category : Science
ISBN : 9780801899805

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Mechanism, Experiment, Disease by Domenico Bertoloni Meli Pdf

A leading early modern anatomist and physician, Marcello Malpighi often compared himself to that period’s other great mind—Galileo. Domenico Bertoloni Meli here explores Malpighi’s work and places it in the context of seventeenth-century intellectual life. Malpighi’s interests were wide and varied. As a professor at the University of Bologna, he confirmed William Harvey’s theory of the circulation of blood; published groundbreaking studies of human organs; made important discoveries about the anatomy of silkworms; and examined the properties of plants. He sought to apply his findings to medical practice. By analyzing Malpighi’s work, the author provides novel perspectives not only on the history of anatomy but also on the histories of science, philosophy, and medicine. Through the lens of Malpighi and his work, Bertoloni Meli investigates a range of important themes, from sense perception to the meaning of Galenism in the seventeenth century. Bertoloni Meli contends that to study science and medicine in the seventeenth century one needs to understand how scholars and ideas crossed disciplinary boundaries. He examines Malpighi’s work within this context, describing how anatomical knowledge was achieved and transmitted and how those processes interacted with the experimental and mechanical philosophies, natural history, and medical practice. Malpighi was central in all of these developments, and his work helped redefine the intellectual horizon of the time. Bertoloni Meli’s critical study of this key figure and the works of his contemporaries—including Borelli, Swammerdam, Redi, and Ruysch—opens a wonderful window onto the scientific and medical worlds of the seventeenth century.

Mechanism

Author : Domenico Bertoloni Meli
Publisher : University of Pittsburgh Press
Page : 312 pages
File Size : 47,6 Mb
Release : 2019-04-02
Category : Science
ISBN : 9780822986522

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Mechanism by Domenico Bertoloni Meli Pdf

The mechanical philosophy first emerged as a leading player on the intellectual scene in the early modern period—seeking to explain all natural phenomena through the physics of matter and motion—and the term mechanism was coined. Over time, natural phenomena came to be understood through machine analogies and explanations and the very word mechanism, a suggestive and ambiguous expression, took on a host of different meanings. Emphasizing the important role of key ancient and early modern protagonists, from Galen to Robert Boyle, this book offers a historical investigation of the term mechanism from the late Renaissance to the end of the seventeenth century, at a time when it was used rather frequently in complex debates about the nature of the notion of the soul. In this rich and detailed study, Domenico Bertoloni Meli focuses on strategies for discussing the notion of mechanism in historically sensitive ways; the relation between mechanism, visual representation, and anatomy; the usage and meaning of the term in early modern times; and Marcello Malpighi and the problems of fecundation and generation, among the most challenging topics to investigate from a mechanistic standpoint.

Mechanisms of Disease

Author : Stephen Tomlinson,Anthony Michael Heagerty,Anthony P. Weetman
Publisher : Unknown
Page : 513 pages
File Size : 43,9 Mb
Release : 1997
Category : Medical
ISBN : 0521461804

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Mechanisms of Disease by Stephen Tomlinson,Anthony Michael Heagerty,Anthony P. Weetman Pdf

An innovative undergraduate medical text which focuses on mechanisms of disease.

Mechanisms of Disease

Author : David O. Slauson,Barry J. Cooper
Publisher : Unknown
Page : 472 pages
File Size : 54,7 Mb
Release : 2002
Category : Pathology
ISBN : UOM:39015053365170

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Mechanisms of Disease by David O. Slauson,Barry J. Cooper Pdf

For nearly 20 years, Slauson-Cooper has been the book of choice in general veterinary pathology. Now totally revised and updated, this new third edition continues to focus on recent advances in the understanding of the complex mechanisms by which mammals become sick. It introduces readers to disease concepts inherent in clinical medicine through the study of pathogenetic mechanisms, and stresses the importance of critical thinking throughout. Still the only text devoted to general veterinary pathology, MECHANISMS OF DISEASE, 3rd Edition, strikes a good balance between the detail required for sophisticated explanations of disease mechanisms and "information overload."

Mechanism and Pharmacodynamic Material Basis of Neurodegenerative Disease Therapies

Author : Zhi Sun,Erxi Wu,Yi Wang
Publisher : Frontiers Media SA
Page : 168 pages
File Size : 49,7 Mb
Release : 2023-08-25
Category : Medical
ISBN : 9782832531662

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Mechanism and Pharmacodynamic Material Basis of Neurodegenerative Disease Therapies by Zhi Sun,Erxi Wu,Yi Wang Pdf

Neurodegenerative diseases are debilitating disorders defined as loss of function or progressive destructing structure of the nervous system with high prevalence among the aging population. These diseases mainly include Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and amyotrophic lateral sclerosis (ALS). They are significantly associated with age and degeneration, becoming a devastating global health issue as a result of the growth of mean life expectancy worldwide. Few or no effective treatments are available for age-related neurodegenerative diseases, causing large socioeconomic and personal costs. The last 15 years have seen a boom in the use and integration of “omic” approaches (such as genomic, transcriptomic, epigenomic and metabolomic techniques) to study neurodegenerative disease in an unprecedented way. While, to date, no therapy based on these approaches is available to cure neurodegenerative diseases. Therefore, it is necessary to search for new, safe, and effective drug candidates and treatment strategies. In this Research Topic, our prime focus would be on the use and integration of “omic” approaches to study biomarkers, pathogenesis, disease progression and new therapeutic target of neurodegenerative diseases, so as to search for new, safe, and effective drug candidates.

Infectious Disease in the Aging

Author : Thomas Yoshikawa,Dean Norman
Publisher : Springer Science & Business Media
Page : 520 pages
File Size : 51,8 Mb
Release : 2009-06-12
Category : Medical
ISBN : 9781603275347

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Infectious Disease in the Aging by Thomas Yoshikawa,Dean Norman Pdf

Because aging is accompanied by a steady decline in resistance to infectious diseases, the diagnosis and treatment of these diseases in the elderly is not only much more complex, but also often quite different from that for younger patients. In the second edition of Infectious Disease in the Aging: A Clinical Handbook, a panel of well known and highly experienced geriatric physicians and infectious disease experts review the most important common infections affecting the elderly and delineate their well-proven diagnostic, therapeutic, and preventive techniques. Among the illnesses discussed are urinary tract infections, pneumonia, ocular infections, tuberculosis, and fungal and viral infections. In addition, there are detailed discussions of sepsis, infective endocarditis, intraabdominal infections, bacterial meningitis, osteomyelitis and septic arthritis, and prosthetic device infections.

Subject Index of Current Research Grants and Contracts Administered by the National Heart, Lung and Blood Institute

Author : National Heart, Lung, and Blood Institute
Publisher : Unknown
Page : 554 pages
File Size : 55,6 Mb
Release : 1977
Category : Cardiovascular system
ISBN : IND:30000099201752

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Subject Index of Current Research Grants and Contracts Administered by the National Heart, Lung and Blood Institute by National Heart, Lung, and Blood Institute Pdf

Mechanisms in the Pathogenesis of Enteric Diseases 2

Author : Prem S. Paul,David H. Francis
Publisher : Springer Science & Business Media
Page : 331 pages
File Size : 53,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461541431

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Mechanisms in the Pathogenesis of Enteric Diseases 2 by Prem S. Paul,David H. Francis Pdf

This book, Mechanisms in the Pathogenesis of Enteric Diseases 2, is an out come of the Second International Rushmore Conference on Mechanisms in the Pathogenesis of Enteric Diseases, held September 3D-October 3, 1998 in Rapid City, South Dakota, USA. Its chapters represent many of the reviews and papers presented at the conference. The meeting was organized by members of the North-Central Regional Research Committee "NC-62", a consortium of researchers of bovine and swine enteric diseases from land-grant institutions supported by the United States Department of Agriculture. The Rushmore Conferences were conceived as a forum for an interdiscipli nary discussion of mechanisms of infectious enteric diseases. It was intended that such a discussion would stimulate cross-pollination of ideas, and nurture synergistic collabora tions among scientists who might otherwise not interact. Enteric diseases are caused by widely divergent pathogens and parasites in broadly different settings, and affect multi ple organ systems. Some enteric diseases affect a single species, while others may affect multiple species, perhaps including human beings. Some enteric diseases were present in antiquity, while others have recently emerged. Knowledge regarding a particular disease or pathogen has frequently proven useful in understanding another disease or pathogen, because common themes in pathogenesis exist. As this knowledge base grows,strategies in the prevention and control of various enteric diseases often converge. Cross-discipli nary discussions and collaborations facilitate growth of this knowledge base, as well as development of tools for disease interdiction.

Evaluating Evidence of Mechanisms in Medicine

Author : Veli-Pekka Parkkinen,Christian Wallmann,Michael Wilde,Brendan Clarke,Phyllis Illari,Michael P Kelly,Charles Norell,Federica Russo,Beth Shaw,Jon Williamson
Publisher : Springer
Page : 125 pages
File Size : 49,9 Mb
Release : 2018-07-13
Category : Medical
ISBN : 9783319946108

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Evaluating Evidence of Mechanisms in Medicine by Veli-Pekka Parkkinen,Christian Wallmann,Michael Wilde,Brendan Clarke,Phyllis Illari,Michael P Kelly,Charles Norell,Federica Russo,Beth Shaw,Jon Williamson Pdf

This book is open access under a CC BY license. This book is the first to develop explicit methods for evaluating evidence of mechanisms in the field of medicine. It explains why it can be important to make this evidence explicit, and describes how to take such evidence into account in the evidence appraisal process. In addition, it develops procedures for seeking evidence of mechanisms, for evaluating evidence of mechanisms, and for combining this evaluation with evidence of association in order to yield an overall assessment of effectiveness. Evidence-based medicine seeks to achieve improved health outcomes by making evidence explicit and by developing explicit methods for evaluating it. To date, evidence-based medicine has largely focused on evidence of association produced by clinical studies. As such, it has tended to overlook evidence of pathophysiological mechanisms and evidence of the mechanisms of action of interventions. The book offers a useful guide for all those whose work involves evaluating evidence in the health sciences, including those who need to determine the effectiveness of health interventions and those who need to ascertain the effects of environmental exposures.

Exosomes in Cardiovascular Diseases: Mechanism, Diagnosis and Therapy

Author : Hongyun Wang,Junjie Xiao,Yunlong Huang
Publisher : Frontiers Media SA
Page : 151 pages
File Size : 55,6 Mb
Release : 2022-11-23
Category : Medical
ISBN : 9782832506905

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Exosomes in Cardiovascular Diseases: Mechanism, Diagnosis and Therapy by Hongyun Wang,Junjie Xiao,Yunlong Huang Pdf

Targeted drug discovery in ectopic calcification: Mechanism, prospect, and clinical application

Author : Kang Xu,Charareh Pourzand,Jing Xie,Anna Malashicheva
Publisher : Frontiers Media SA
Page : 173 pages
File Size : 40,8 Mb
Release : 2023-05-26
Category : Science
ISBN : 9782832524213

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Targeted drug discovery in ectopic calcification: Mechanism, prospect, and clinical application by Kang Xu,Charareh Pourzand,Jing Xie,Anna Malashicheva Pdf

Niedermeyer's Electroencephalography

Author : Donald L. Schomer,Fernando H. Lopes da Silva
Publisher : Oxford University Press
Page : 1265 pages
File Size : 45,8 Mb
Release : 2018
Category : Medical
ISBN : 9780190228484

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Niedermeyer's Electroencephalography by Donald L. Schomer,Fernando H. Lopes da Silva Pdf

Niedermeyer's Electroencephalography: Basic Principles, Clinical Applications, and Related Fields, Seventh Edition keeps the clinical neurophysiologist on the forefront of medical advancements. This authoritative text covers basic neurophysiology, neuroanatomy, and neuroimaging to provide a better understanding of clinical neurophysiological findings. This edition further delves into current state-of-the-art recording EEG activity both in the normal clinical environment and unique situations such as the intensive care unit, operating rooms, and epilepsy monitoring suites. As computer technology evolves, so does the integration of analytical methods that significantly affect the reader's interpretations of waveforms and trends that are occurring on long-term monitoring sessions. Compiled and edited by Donald L. Schomer and Fernando H. Lopes da Silva, along with a global team of experts, they collectively bring insight to crucial sections including basic principles of EEG and MEG, normal EEG, EEG in a clinical setting, clinical EEG in seizures and epilepsy, complementary and special techniques, event-related EEG phenomena, and shed light on the future of EEG and clinical neurophysiology. Akin to an encyclopedia of everything EEG, this comprehensive work is perfect for neurophysiology fellows, as well as neurology, neurosurgery, and general medical residents, and for the interns and medical students, and is a one-stop-shop for anyone training in EEG or preparing for neurophysiology or epilepsy board exams.

Molecular mechanism of vascular remodelling and target organ damage

Author : Jia Qi,Qingxun Hu,Jintao Wang,Haineng Xu,Yanggang Yuan
Publisher : Frontiers Media SA
Page : 160 pages
File Size : 52,9 Mb
Release : 2023-06-05
Category : Medical
ISBN : 9782832525203

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Molecular mechanism of vascular remodelling and target organ damage by Jia Qi,Qingxun Hu,Jintao Wang,Haineng Xu,Yanggang Yuan Pdf