Author : Alison Davis
Publisher : Unknown
Page : 128 pages
File Size : 42,5 Mb
Release : 2003
Category : Electronic
ISBN : OCLC:1222077636
Medicines by Design
Alison Davis
Medicines By Design
Medicines By Design Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Medicines By Design book. This book definitely worth reading, it is an incredibly well-written.
Aulton's Pharmaceutics
Michael E. Aulton,Kevin Taylor
Author : Michael E. Aulton,Kevin Taylor
Publisher : Elsevier Health Sciences
Page : 909 pages
File Size : 44,8 Mb
Release : 2013
Category : Medical
ISBN : 9780702042904
Aulton's Pharmaceutics by Michael E. Aulton,Kevin Taylor Pdf
"Pharmaceutics is the art of pharmaceutical preparations. It encompasses design of drugs, their manufacture and the elimination of micro-organisms from the products. This book encompasses all of these areas."--Provided by publisher.
Miraculous Medicines and the Chemistry of Drug Design
Nathan Keighley
Author : Nathan Keighley
Publisher : CRC Press
Page : 126 pages
File Size : 46,8 Mb
Release : 2020-12-14
Category : Science
ISBN : 9781000285376
Miraculous Medicines and the Chemistry of Drug Design by Nathan Keighley Pdf
The subject of chemistry is widely acknowledged as being conceptually challenging, and regarded with a perceived elitism. This book aims to address this dilemma by breaking down the fundamentals of organic chemistry and its importance in medicine, so that readers with any or no background education in chemistry can access the material and gain an appreciation and understanding for the subject. The text is written in a clear and concise manner, using appropriate figures, to explain how the medicine we are so familiar with is designed and produced. Undergraduate students, medical and nursing students, and general audiences will benefit from the accessible format and enjoyable read. Key Features: User-friendly text dealing with the chemical sciences for the non-scientist Public understanding of science at the interface of biology and chemistry is in high demand The book serves to introduce organic chemistry and its relevance to medicine Describes the foundational principles of chemistry without losing the systematic rigor of the subject
Pharmaceutics
Philip Denton,Chris Rostron
Author : Philip Denton,Chris Rostron
Publisher : Oxford University Press
Page : 288 pages
File Size : 50,5 Mb
Release : 2013-07-25
Category : Medical
ISBN : 9780199655311
Pharmaceutics by Philip Denton,Chris Rostron Pdf
Pharmaceutics: the science of medicine design explores the different forms that medicines can take, and demonstrates how being able to select the best form - be it a tablet, injectable liquid, or an inhaled gas - requires an understanding of how chemicals behave in different physical states.
Design and Manufacture of Pharmaceutical Tablets
Reynir Eyjolfsson
Author : Reynir Eyjolfsson
Publisher : Academic Press
Page : 68 pages
File Size : 44,9 Mb
Release : 2014-10-09
Category : Medical
ISBN : 9780128021873
Design and Manufacture of Pharmaceutical Tablets by Reynir Eyjolfsson Pdf
Design and Manufacture of Pharmaceutical Tablets offers real world solutions and outcomes of formulation and processing challenges of pharmaceutical tablets. This book includes numerous practical examples related to actual formulations that have been validated and marketed and covers important data in the areas of stability, dissolution, bioavailibity and processing. It provides important background and theoretical information on design and manufacturing and includes a full section dedicated to design experimental methodology and statistics. In addition, this book offers a a general discussion of excipients used in proper tablet design along with practical examples related to excipients. Drug development scientists in industry and academia, as well as students in the pharmaceutical sciences will greatly benefit from the practical knowledge and case examples provided throughout this book. Incorporates important mathematical models and computational applications Includes unique content on central composite design and augmented simplex lattice Provides background on important design principles with emphasis on quality-based design (QBD) of pharmaceutical dosage forms
Communicating Clearly About Medicines
National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Roundtable on Health Literacy
Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Roundtable on Health Literacy
Publisher : National Academies Press
Page : 125 pages
File Size : 52,5 Mb
Release : 2017-10-08
Category : Medical
ISBN : 9780309461856
Communicating Clearly About Medicines by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Roundtable on Health Literacy Pdf
Research conducted over the past two decades has shown that poor patient understanding of medication instructions is an important contributor to the more than 1 million medication errors and adverse drug events that lead to office and emergency room visits, hospitalizations, and even death. Patients who have limited literacy skills, who have multiple comorbidities, and who are elderly face the greatest risk, and limited literacy skills are significantly associated with inadequate understanding and use of prescription instructions and precautions. The Agency for Healthcare Research and Quality notes that only 12 percent of U.S. adults have proficient health literacy that allows them to interpret a prescription label correctly. Given the importance of health literacy to the proper use of medications, and the apparent lack of progress in improving medication adherence, the Roundtable on Health Literacy formed an ad hoc committee to plan and conduct a 1-day public workshop that featured invited presentations and discussion of the role and challenges regarding clarity of communication on medication. Participants focused on using health literacy principles to address clarity of materials, decision aids, and other supportive tools and technologies regarding risks, benefits, alternatives, and health plan coverage. This publication summarizes the presentations and discussions from the workshop.
Pharmaceutical Quality by Design
Sarwar Beg,Md Saquib Hasnain
Author : Sarwar Beg,Md Saquib Hasnain
Publisher : Academic Press
Page : 448 pages
File Size : 47,7 Mb
Release : 2019-03-27
Category : Business & Economics
ISBN : 9780128163726
Pharmaceutical Quality by Design by Sarwar Beg,Md Saquib Hasnain Pdf
Pharmaceutical Quality by Design: Principles and Applications discusses the Quality by Design (QbD) concept implemented by regulatory agencies to ensure the development of a consistent and high-quality pharmaceutical product that safely provides the maximum therapeutic benefit to patients. The book walks readers through the QbD framework by covering the fundamental principles of QbD, the current regulatory requirements, and the applications of QbD at various stages of pharmaceutical product development, including drug substance and excipient development, analytical development, formulation development, dissolution testing, manufacturing, stability studies, bioequivalence testing, risk and assessment, and clinical trials. Contributions from global leaders in QbD provide specific insight in its application in a diversity of pharmaceutical products, including nanopharmaceuticals, biopharmaceuticals, and vaccines. The inclusion of illustrations, practical examples, and case studies makes this book a useful reference guide to pharmaceutical scientists and researchers who are engaged in the formulation of various delivery systems and the analysis of pharmaceutical product development and drug manufacturing process. Discusses vital QbD precepts and fundamental aspects of QbD implementation in the pharma, biopharma and biotechnology industries Provides helpful illustrations, practical examples and research case studies to explain QbD concepts to readers Includes contributions from global leaders and experts from academia, industry and regulatory agencies
Making Medicines Affordable
National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on Ensuring Patient Access to Affordable Drug Therapies
Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on Ensuring Patient Access to Affordable Drug Therapies
Publisher : National Academies Press
Page : 235 pages
File Size : 40,6 Mb
Release : 2018-03-01
Category : Medical
ISBN : 9780309468084
Making Medicines Affordable by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on Ensuring Patient Access to Affordable Drug Therapies Pdf
Thanks to remarkable advances in modern health care attributable to science, engineering, and medicine, it is now possible to cure or manage illnesses that were long deemed untreatable. At the same time, however, the United States is facing the vexing challenge of a seemingly uncontrolled rise in the cost of health care. Total medical expenditures are rapidly approaching 20 percent of the gross domestic product and are crowding out other priorities of national importance. The use of increasingly expensive prescription drugs is a significant part of this problem, making the cost of biopharmaceuticals a serious national concern with broad political implications. Especially with the highly visible and very large price increases for prescription drugs that have occurred in recent years, finding a way to make prescription medicinesâ€"and health care at largeâ€"more affordable for everyone has become a socioeconomic imperative. Affordability is a complex function of factors, including not just the prices of the drugs themselves, but also the details of an individual's insurance coverage and the number of medical conditions that an individual or family confronts. Therefore, any solution to the affordability issue will require considering all of these factors together. The current high and increasing costs of prescription drugsâ€"coupled with the broader trends in overall health care costsâ€"is unsustainable to society as a whole. Making Medicines Affordable examines patient access to affordable and effective therapies, with emphasis on drug pricing, inflation in the cost of drugs, and insurance design. This report explores structural and policy factors influencing drug pricing, drug access programs, the emerging role of comparative effectiveness assessments in payment policies, changing finances of medical practice with regard to drug costs and reimbursement, and measures to prevent drug shortages and foster continued innovation in drug development. It makes recommendations for policy actions that could address drug price trends, improve patient access to affordable and effective treatments, and encourage innovations that address significant needs in health care.
The Design and Development of Novel Drugs and Vaccines
Tarun Kumar Bhatt,Surendra Nimesh
Author : Tarun Kumar Bhatt,Surendra Nimesh
Publisher : Academic Press
Page : 310 pages
File Size : 43,6 Mb
Release : 2021-01-21
Category : Business & Economics
ISBN : 9780128214756
The Design and Development of Novel Drugs and Vaccines by Tarun Kumar Bhatt,Surendra Nimesh Pdf
The Design and Development of Novel Drugs and Vaccines: Principles and Protocols presents both in silico methods and experimental protocols for vaccine and drug design and development, critically reviewing the most current research and emphasizing approaches and technologies that accelerate and lower the cost of product development. Sections review the technologies and approaches used to identify, characterize and establish a protein as a new drug and vaccine target, cover several molecular methods for in vitro studies of the desired target, and present various physiological parameters for in vivo studies. The book includes preclinical trials and research, along with information on FDA approval. Covers both in silico methods and experimental protocols for vaccine and drug development in a single, accessible volume Offers a holistic accounting of how developments in bioinformatics and large experimental datasets can be used in the development of vaccines and drugs Shows researchers the entire gamut of current therapies, ranging from computational inputs to animal studies Reviews the most current, cutting-edge research available on vaccine and drug design and development
Quality by Design for Biopharmaceutical Drug Product Development
Feroz Jameel,Susan Hershenson,Mansoor A. Khan,Sheryl Martin-Moe
Author : Feroz Jameel,Susan Hershenson,Mansoor A. Khan,Sheryl Martin-Moe
Publisher : Springer
Page : 710 pages
File Size : 50,6 Mb
Release : 2015-04-01
Category : Medical
ISBN : 9781493923168
Quality by Design for Biopharmaceutical Drug Product Development by Feroz Jameel,Susan Hershenson,Mansoor A. Khan,Sheryl Martin-Moe Pdf
This volume explores the application of Quality by Design (QbD) to biopharmaceutical drug product development. Twenty-eight comprehensive chapters cover dosage forms, liquid and lyophilized drug products. The introductory chapters of this book define key elements of QbD and examine how these elements are integrated into drug product development. These chapters also discuss lessons learned from the FDA Office of Biotechnology Products pilot program. Following chapters demonstrate how QbD is used for formulation development ranging from screening of formulations to developability assessment to development of lyophilized and liquid formats. The next few chapters study the use of small-scale and surrogate models as well as QbD application to drug product processes such as drug substance freezing and thawing, mixing, sterile filtration, filling, lyophilization, inspection and shipping and handling. Later chapters describe more specialized applications of QbD in the drug product realm. This includes the use of QbD in primary containers, devices and combination product development. The volume also explores QbD applied to vaccine development, automation, mathematical modeling and monitoring, and controlling processes and defining control strategies. It concludes with a discussion on the application of QbD to drug product technology transfer as well as overall regulatory considerations and lifecycle management. Quality by Design for Biopharmaceutical Drug Product Development is an authoritative resource for scientists and researchers interested in expanding their knowledge on QbD principles and uses in creating better drugs.
New Drug Development
J. Rick Turner
Author : J. Rick Turner
Publisher : John Wiley & Sons
Page : 298 pages
File Size : 42,8 Mb
Release : 2007-07-27
Category : Mathematics
ISBN : 9780470073735
New Drug Development by J. Rick Turner Pdf
This book acquaints students and practitioners in the related fields of pharmaceutical sciences, clinical trials, and evidence-based medicine with the necessary study design concepts and statistical practices to allow them to understand how drug developers plan and evaluate their drug development. Two goals of the book are to make the material accessible to readers with minimal background in research and to be straightforward enough for self-taught purposes. By bringing the topic from the early discovery phase to clinical trials and medical practice, the book provides an indispensable overview of an otherwise confusing and fragmented set of topics. The author’s experience as a respected scientist, teacher of statistics, and one who has worked in the clinical trials arena makes him well suited to write such a treatise.
Pharmaceutical Quality by Design
Walkiria S. Schlindwein,Mark Gibson
Author : Walkiria S. Schlindwein,Mark Gibson
Publisher : John Wiley & Sons
Page : 375 pages
File Size : 46,5 Mb
Release : 2018-03-19
Category : Science
ISBN : 9781118895207
Pharmaceutical Quality by Design by Walkiria S. Schlindwein,Mark Gibson Pdf
A practical guide to Quality by Design for pharmaceutical product development Pharmaceutical Quality by Design: A Practical Approach outlines a new and proven approach to pharmaceutical product development which is now being rolled out across the pharmaceutical industry internationally. Written by experts in the field, the text explores the QbD approach to product development. This innovative approach is based on the application of product and process understanding underpinned by a systematic methodology which can enable pharmaceutical companies to ensure that quality is built into the product. Familiarity with Quality by Design is essential for scientists working in the pharmaceutical industry. The authors take a practical approach and put the focus on the industrial aspects of the new QbD approach to pharmaceutical product development and manufacturing. The text covers quality risk management tools and analysis, applications of QbD to analytical methods, regulatory aspects, quality systems and knowledge management. In addition, the book explores the development and manufacture of drug substance and product, design of experiments, the role of excipients, multivariate analysis, and include several examples of applications of QbD in actual practice. This important resource: Covers the essential information about Quality by Design (QbD) that is at the heart of modern pharmaceutical development Puts the focus on the industrial aspects of the new QbD approach Includes several illustrative examples of applications of QbD in practice Offers advanced specialist topics that can be systematically applied to industry Pharmaceutical Quality by Design offers a guide to the principles and application of Quality by Design (QbD), the holistic approach to manufacturing that offers a complete understanding of the manufacturing processes involved, in order to yield consistent and high quality products.
Design of Experiments for Pharmaceutical Product Development
Sarwar Beg
Author : Sarwar Beg
Publisher : Springer Nature
Page : 99 pages
File Size : 42,9 Mb
Release : 2021-01-12
Category : Medical
ISBN : 9789813347175
Design of Experiments for Pharmaceutical Product Development by Sarwar Beg Pdf
This book volume provides complete and updated information on the applications of Design of Experiments (DoE) and related multivariate techniques at various stages of pharmaceutical product development. It discusses the applications of experimental designs that shall include oral, topical, transdermal, injectables preparations, and beyond for nanopharmaceutical product development, leading to dedicated case studies on various pharmaceutical experiments through illustrations, art-works, tables and figures. This book is a valuable guide for all academic and industrial researchers, pharmaceutical and biomedical scientists, undergraduate and postgraduate research scholars, pharmacists, biostatisticians, biotechnologists, formulations and process engineers, regulatory affairs and quality assurance personnel.
Pharmaceutical Experimental Design And Interpretation
N. Anthony Armstrong,K. C. James
Author : N. Anthony Armstrong,K. C. James
Publisher : CRC Press
Page : 294 pages
File Size : 45,8 Mb
Release : 2002-09-11
Category : Medical
ISBN : 020348309X
Pharmaceutical Experimental Design And Interpretation by N. Anthony Armstrong,K. C. James Pdf
This work provides a description of the principles of experimental design and their application to pharmaceutical research. It includes worked examples taken from a wide variety of pharmaceutical techniques and processes.
Medicines by Design
Anonim
Author : Anonim
Publisher : NIGMS
Page : 60 pages
File Size : 48,6 Mb
Release : 1993
Category : Drugs
ISBN : 8210379456XXX