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Author : Joana M. Gaspar,Humberto M. Carvalho,Alberto Camacho-Morales
Publisher : Frontiers Media SA
Page : 73 pages
File Size : 47,8 Mb
Release : 2022-01-20
Category : Science
ISBN : 9782889741168
Author : M. Mohamed Essa,M. Walid Qoronfleh
Publisher : Springer Nature
Page : 700 pages
File Size : 55,9 Mb
Release : 2020-01-31
Category : Medical
ISBN : 9783030304027
The book focuses on implications of traditional and processed foods for autism spectrum disorder (ASD) intervention and management. Numerous phytonutrients and pharmacologically active compounds in edible natural products and diet could influence and offer protection to neuronal dysfunction that occurs due to ASD. The neuroprotective effects of various fruits, vegetables, nuts and seeds phytochemicals, and other natural bioactive ingredients against ASD and related conditions are discussed. Topics such as the possible neuroprotective mechanism of action of these foods and the therapeutic role of antioxidants in relation to ASD are addressed. This book also highlights the scope of using anti-inflammatory agents and antioxidants to promote neurogenesis and improve other symptoms in ASD. It emphasizes personalized nutritional approaches with dietary management of neurodevelopmental disorders/ASD cases. Information in this book is relevant to researchers in the field of complementary and alternative medicine, nutraceuticals, neuroscience, agriculture, nutrition, and food science. This volume is beneficial to students of varying levels, and across multiple disciplines.
Author : Andreas M. Grabrucker
Publisher : Unknown
Page : 117 pages
File Size : 42,9 Mb
Release : 2021
Category : Electronic
ISBN : OCLC:1280592589
Autism spectrum disorders are developmental disorders. Individuals with autism spectrum disorders develop differently. These differences are usually present in social interaction, communication, and sensory processing, and become visible through a wide variety of behavioral responses that differ from individuals without autism spectrum disorders. Despite significant research efforts, the exact causes of autism spectrum disorders remain poorly understood; however, researchers have gained extensive insights into possible pathomechanisms, even at the molecular level of cells. Many diagnostic criteria have been developed, adapted, and improved. The eight chapters in this book highlight the current state-of-the-art in many areas of autism spectrum disorders. Chapter 1 provides an overview of the epidemiology of autism spectrum disorders and the current knowledge of the underlying pathogenic mechanisms. Chapter 2 summarizes the diagnostic criteria and procedures and highlights present and upcoming therapeutic strategies. Chapter 3 reviews the adverse events and trauma in people with autism spectrum disorders. Chapters 4 and 5 focus on atypical sensory processing, and Chapter 6 discusses the genetic overlap of autism spectrum disorders with other neuropsychiatric disorders such as attention deficit hyperactivity disorder (ADHD), depression, and schizophrenia. Chapter 7 focuses on the contribution of abnormalities in mitochondria, and chapter 8 discusses gut-brain interactions and a potential role for microbiota in autism spectrum disorders. This book is aimed primarily at clinicians and scientists, but many areas will also be of interest to the layperson.
Author : Detlev Boison,Susan Masino
Publisher : Oxford University Press
Page : 657 pages
File Size : 40,8 Mb
Release : 2016
Category : Medical
ISBN : 9780199322299
Homeostatic Control of Brain Function offers a broad view of brain health and diverse perspectives for potential treatments, targeting key areas such as mitochondria, the immune system, epigenetic changes, and regulatory molecules such as ions, neuropeptides, and neuromodulators. Loss of homeostasis becomes expressed as a diverse array of neurological disorders. Each disorder has multiple comorbidities - with some crossing over several conditions - and often disease-specific treatments remain elusive. When current pharmacological therapies result in ineffective and inadequate outcomes, therapies to restore and maintain homeostatic functions can help improve brain health, no matter the diagnosis. Employing homeostatic therapies may lead to future cures or treatments that address multiple comorbidities. In an age where brain diseases such as Alzheimer's or Parkinson's are ever present, the incorporation of homeostatic techniques could successfully promote better overall brain health. Key Features include · A focus on the homeostatic controls that significantly depend on the way one lives, eats, and drinks. · Highlights from emerging research in non-pharmaceutical therapies including botanical medications, meditation, diet, and exercise. · Incorporation of homeostatic therapies into existing basic and clinical research paradigms. · Extensive scientific basic and clinical research ranging from molecules to disorders. · Emerging practical information for improving homeostasis. · Examples of homeostatic therapies in preventing and delaying dysfunction. Both editors, Detlev Boison and Susan Masino, bring their unique expertise in homeostatic research to the overall scope of this work. This book is accessible to all with an interest in brain health; scientist, clinician, student, and lay reader alike.
Author : Feiyong Jia,Tingyu Li,Wouter G. Staal,Khaled Saad
Publisher : Frontiers Media SA
Page : 185 pages
File Size : 49,6 Mb
Release : 2023-08-02
Category : Medical
ISBN : 9782832531181
Author : Neal Halfon,Christopher B. Forrest,Richard M. Lerner,Elaine M. Faustman
Publisher : Springer
Page : 667 pages
File Size : 45,6 Mb
Release : 2017-11-20
Category : Medical
ISBN : 9783319471433
This book is open access under a CC BY 4.0 license. This handbook synthesizes and analyzes the growing knowledge base on life course health development (LCHD) from the prenatal period through emerging adulthood, with implications for clinical practice and public health. It presents LCHD as an innovative field with a sound theoretical framework for understanding wellness and disease from a lifespan perspective, replacing previous medical, biopsychosocial, and early genomic models of health. Interdisciplinary chapters discuss major health concerns (diabetes, obesity), important less-studied conditions (hearing, kidney health), and large-scale issues (nutrition, adversity) from a lifespan viewpoint. In addition, chapters address methodological approaches and challenges by analyzing existing measures, studies, and surveys. The book concludes with the editors’ research agenda that proposes priorities for future LCHD research and its application to health care practice and health policy. Topics featured in the Handbook include: The prenatal period and its effect on child obesity and metabolic outcomes. Pregnancy complications and their effect on women’s cardiovascular health. A multi-level approach for obesity prevention in children. Application of the LCHD framework to autism spectrum disorder. Socioeconomic disadvantage and its influence on health development across the lifespan. The importance of nutrition to optimal health development across the lifespan. The Handbook of Life Course Health Development is a must-have resource for researchers, clinicians/professionals, and graduate students in developmental psychology/science; maternal and child health; social work; health economics; educational policy and politics; and medical law as well as many interrelated subdisciplines in psychology, medicine, public health, mental health, education, social welfare, economics, sociology, and law.
Author : Lawrence H. Lash,Dean P. Jones
Publisher : Elsevier
Page : 528 pages
File Size : 40,6 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483218618
Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.
Author : David Quentin Beversdorf,Craig Andrew Erickson,Paul Wang,Thomas Frazier
Publisher : Frontiers Media SA
Page : 153 pages
File Size : 45,8 Mb
Release : 2023-04-17
Category : Medical
ISBN : 9782832515686
Many therapeutic interventions for autism spectrum disorder fail when they are examined in a clinical trial. Frequently, there is a subset of patients that responds very well to the intervention, while others do not, and the overall result does not yield a positive result. As autism spectrum disorder is highly heterogeneous in its underlying genetics and other etiological risk factors, as well as its heterogeneous phenotypic manifestation, this variability in response to any specific treatment is not entirely surprising. However, it remains a challenge to meaningfully subtype this heterogeneity for targeted treatment. The purpose of this research topic is to solicit articles that address the heterogeneity in autism spectrum disorder in a manner that may meaningfully contribute to targeted treatment approaches. Studies that address the heterogeneity of autism that could theoretically lead to targeted treatment, and studies that more directly address the use of a marker in association with response to a treatment, are both aspects that will contribute to this purpose. It is hoped that this Research Topic will yield articles that can help advance the field towards precision medicine in autism spectrum disorders. Manuscripts that contribute to the specification of the heterogeneity of autism spectrum disorder in a manner that could theoretically lead to targeted treatment would be appropriate for this research topic. Additionally, articles that utilize subtyping in relation to response to treatment would be appropriate for this research topic.
Author : Suzanne Goh, MD
Publisher : Penguin
Page : 353 pages
File Size : 55,7 Mb
Release : 2024-04-09
Category : Psychology
ISBN : 9780593712733
An essential primer based on a renowned new model of care that is comprehensive and research based, while honoring the uniqueness of every child An estimated one in thirty-six children in the United States is diagnosed with autism. New research has shed light on the many factors that determine a child’s trajectory—but many parents are still navigating this complex terrain without a road map. Pediatric neurologist Dr. Suzanne Goh has spent decades working with autistic children, and in this practical and research-based guide she shares her renowned and revolutionary model of care: an innovative, whole-child approach that combines optimal medical treatment with the most effective strategies for advancing cognition, communication, and behavior. Demystifying a wide range of diagnostics and therapies and offering new insights into the neurological, biochemical, behavioral, and social factors that play a role in successful outcomes, the book is an essential resource for understanding all of autism—a strengths-based approach that helps parents design a comprehensive treatment plan. It is also a celebration of what each autistic person brings to the world—and how parents can best nurture the remarkable uniqueness of their child while setting them up for the future they envision.
Author : Sam Goldstein,Cecil R. Reynolds
Publisher : Guilford Press
Page : 588 pages
File Size : 45,5 Mb
Release : 2010-10-19
Category : Psychology
ISBN : 9781609180003
Recognized as the definitive reference in the field, this book addresses a broad range of biologically based disorders that affect children's learning and development. Leading authorities review the genetics of each disorder; its course and outcome; associated developmental, cognitive, and psychosocial challenges; and what clinicians and educators need to know about effective approaches to assessment and intervention. Coverage encompasses more frequently diagnosed learning and behavior problems with a genetic component as well as numerous lower-incidence neurodevelopmental disabilities. Illustrations include 12 color plates.
Author : Danilo Arnone,Emmanuel Stip,Andrés Herane-Vives,Karim Abdel Aziz
Publisher : Frontiers Media SA
Page : 120 pages
File Size : 41,8 Mb
Release : 2022-03-28
Category : Medical
ISBN : 9782889747672
Author : Richard Eugene Frye,Shannon Rose,Lourdes Martorell,Richard G. Boles
Publisher : Frontiers Media SA
Page : 251 pages
File Size : 52,9 Mb
Release : 2020-08-27
Category : Electronic
ISBN : 9782889639588
Author : Mitchell J. Prinstein,Eric A. Youngstrom,Eric J. Mash,Russell A. Barkley
Publisher : Guilford Publications
Page : 930 pages
File Size : 46,6 Mb
Release : 2021-05-19
Category : Psychology
ISBN : 9781462547715
Now completely revised (over 90% new), this definitive practitioner reference and course text comprehensively reviews evidence-based treatments for psychological disorders in children and adolescents. The significantly expanded fourth edition covers an increased number of disorders, as well as transdiagnostic issues and public health concerns. Psychosocial, pharmacological, and complementary therapies are identified and described in well-organized chapters that include rich clinical illustrations. Prominent experts address developmental considerations in treatment and offer guidance for tailoring interventions to each child and family's needs. Prior edition title: Treatment of Childhood Disorders, Third Edition, edited by Eric J. Mash and Russell A. Barkley. New to This Edition *All chapters are new, reflecting over a decade of clinical and empirical developments. *Chapters on additional clinical issues: bipolar disorder, suicidal and nonsuicidal self-injury, obsessive–compulsive disorder, infant and toddler problems, posttraumatic stress disorder, coping and emotion regulation, bereavement, early-onset schizophrenia, personality disorders, childhood obesity, and sleep problems. *Chapters on case conceptualization and evidence-based therapist flexibility. *Illustrative case examples and transcripts added throughout. *Updated for DSM-5; every chapter also considers transdiagnostic and dimensional issues. See also the editors' Assessment of Disorders in Childhood and Adolescence, Fifth Edition.
Author : Deepak M. Kamat,Lalitha Sivaswamy
Publisher : Springer Nature
Page : 765 pages
File Size : 50,9 Mb
Release : 2023-01-01
Category : Medical
ISBN : 9783031104947
Primary health care providers such as pediatricians and family medicine physicians commonly encounter children with neurologic symptoms such as headache, double vision, facial weakness etc. Most books currently available in the specialty of pediatric neurology are “condition” or “disorder” based, and most of them are geared towards pediatric neurologists, not generalists who take care of children. A common thread amongst most currently available books in Pediatric Neurology is that the practitioner already knows what “condition” or “disorder” the child is suffering from. This book focuses on symptoms to a large extent. However, children with chronic neurological conditions will follow up with their primary care physicians after their visit with the sub-specialists. They may have questions or ongoing concerns regarding the diagnosis that has been made or being considered. This book attempts to provide information to the primary care physician regarding management and follow up of such children as well. This book serves as a guide for busy clinicians who take care of children presenting with neurological symptoms- with special emphasis on symptoms that are commonly encountered in clinical practice. For each symptom, a brief introduction is given as well as a definition and epidemiologic information for the given symptom. Readers are also instructed on what historical features and physical examinations are essential in narrowing the differential diagnosis. A recommendation on the management of the condition is then established. Instructions on when one should refer the patient to subspecialists for further evaluation and management are clearly laid out. Finally, a list of appropriate resources is provided for families, as well as clinical pearls that can be quickly scanned when one is pressed for time. The overarching goal of this book is to enable the primary care physician to make a confident diagnosis, triage efficiently and initiate treatment if need be. Written by experts in the field, Symptom-Based Approach to Pediatric Neurology is a valuable resource for evaluation and management of children presenting with neurologic symptoms for primary care providers who take care of children.
Author : Steven C. Schachter
Publisher : Elsevier Health Sciences
Page : 257 pages
File Size : 45,9 Mb
Release : 2022-10-22
Category : Medical
ISBN : 9780323849173
In this issue of Neurologic Clinics, guest editor Dr. Steven C. Schachter brings his considerable expertise to the topic of Epilepsy. Top experts in the field cover key topics such as telemedicine and epilepsy care; wearable technologies and mobile apps in the evaluation and treatment of epilepsy; effects of maternal use of AEDs on child development; sleep and epilepsy; dietary treatments for epilepsy; and more. Contains 15 relevant, practice-oriented topics including racial/ethnic disparities in epilepsy burden and treatment; autism and epilepsy; emerging technologies for epilepsy surgery; prevalence and diagnosis of sexual dysfunction in people with epilepsy; epilepsy in older persons; rescue treatments for seizure clusters; and more. Provides in-depth clinical reviews on epilepsy, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
