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Author : Jochen A. Werner,R. Kim Davis Publisher : Springer Science & Business Media Page : 233 pages File Size : 53,9 Mb Release : 2012-12-06 Category : Medical ISBN : 9783642187223
Metastases in Head and Neck Cancer by Jochen A. Werner,R. Kim Davis Pdf
-Richly illustrated; 109 illustrations, 57 in color -Cover a wide range of diagnostic and theraputic techniques, i.e. MRI, PET, surgical treatment, radiation therapy
This second edition provides a comprehensive view of consolidated and innovative concepts, in terms of both diagnosis and treatment. Written by leading international physicians and investigators, this book emphasizes the necessity of combining local and systemic treatments to achieve the objective of yielding higher cure rates and lower toxicities. Heavily updated from the previous edition, it highlights new surgery and radiotherapy techniques, disease awareness, patient quality of life, and comprehensive management. Head-and-neck cancers are a complex clinical entity and their response to treatment is also known to vary markedly in function of host-related factors. Notwithstanding the impressive progresses observed in the field of imaging, head and neck cancers are often diagnosed at a late stage and the presence of locally advanced disease in a significant number of patients implies the use of aggressive treatments in order to both ensure local disease control and reduce distant metastasis risks. In comparison with the first edition, Head and Neck Cancer, Second Edition provides a detailed update of innovative concepts in chemo- and bio-radiation, viral infection impact on tumor growth and response to treatment, and impact of tumor- and host-related factors on treatment outcome.
Author : Louis B. Harrison,Roy B. Sessions,Waun Ki Hong Publisher : Lippincott Williams & Wilkins Page : 1004 pages File Size : 55,7 Mb Release : 2009 Category : Medical ISBN : 0781771366
Head and Neck Cancer by Louis B. Harrison,Roy B. Sessions,Waun Ki Hong Pdf
This comprehensive, multidisciplinary text addresses all aspects of head and neck cancer and represents a wide spectrum of specialists, including surgical, radiation, and medical oncologists, dentists, pathologists, radiologists, and nurses. The book focuses on a two-part approach to treatment that maximizes the chance for a cure while maintaining a strong emphasis on quality of life. This Third Edition's updated techniques section includes new radiation techniques such as IMRT and IGRT and new endoscopic and laser surgical techniques. Other highlights include a new chapter on reconstructive techniques; significant updates to all site-specific chapters; updates on chemoprevention and molecular targeting; and discussions of new imaging modalities such as fused PET/CT. A companion Website will offer the fully searchable text with all images.
Squamous cell carcinoma of the oral cavity (SCCOC) is one of the most prevalent tumors of the head and neck region. Despite improvements in treatment, the survival of patients with SCCOC has not significantly improved over the past several decades. Most frequently, treatment failure takes the form of local and regional recurrences, but as disease control in these areas improves, SCCOC treatment failures more commonly occur as distant metastasis. The presence of cervical lymph node metastasis is the most reliable adverse prognostic factor in patients with SCCOC, and extracapsular spread (ECS) of cervical lymph nodes metastasis is a particularly reliable predictor of regional and distant recurrence and death from disease. Decisions regarding elective and therapeutic management of cervical lymph node metastases are made mainly on clinical grounds as we cannot always predict cervical lymph node metastasis from the size and extent of invasion of the primary tumors. Therefore the treatment of the neck disease in the management of SCCOC remains controversial. The promise of using biomarker-based treatment decisions has yet to be fully realized due to our poor understanding of the mechanisms of regional and distant metastases of SCCOC. We will summarize the current status of investigations into SCCOC metastases and potential of these studies to impact basic research investigators and clinicians confronting SCCOC in the future.
Critical Issues in Head and Neck Oncology by Jan B. Vermorken,Volker Budach,C. René Leemans,Jean-Pascal Machiels,Piero Nicolai,Brian O'Sullivan Pdf
This is an open access book. With a wealth of exciting data emerging in this rapidly evolving field this book will review the state-of-the-art knowledge with emphasis on multidisciplinary decision and management of head and neck cancer. The book provides significant detail on a wide range of topics including: the role of new targets for treatment, immunotherapy, resistance mechanisms, standardizing molecular profiling programs, and new methods to guide therapeutic approaches. In addition different disease situations are addressed including different treatment approaches in primary disease and in recurrent and/or metastatic disease as well as new developments in pathology, surgery and reconstruction techniques, new systemic therapies in salivary gland cancer, and supportive care and follow-up. All disciplines involved in the treatment of head & neck cancer are covered with a focus on translation into daily practice. The 8th-THNO is designed for medical oncologists, head and neck surgeons, radiation oncologists, otolaryngologists, and other medical professionals involved in the treatment of patients with head and neck cancer.
Cancer of the Head and Neck by Jeffrey Myers,Ehab Hanna Pdf
Offering a comprehensive, multidisciplinary approach to head and neck oncology, Cancer of the Head and Neck, Fifth Edition, delivers authoritative guidance to the entire head and neck cancer care team. Retaining an expert surgical focus that has made it a classic in the field, this edition incorporates new disease- and site-specific chapters as well as a greater emphasis on reconstruction and rehabilitation. Written and edited by globally renowned head and neck surgeons, it’s an indispensable resource for practitioners, trainees, and other health care professionals who care for patients with head and neck cancer.
Head and Neck Cancer by Waun Ki Hong,Randal S. Weber Pdf
Throughout the world, head and neck cancer is a major threat to public health and a significant challenge to both clinicians and basic scientists. Despite extensive efforts in primary prevention, screening, early detection, and therapy, long-term survival rates have not improved substantially in the last three decades. This book covers a wide range of exciting new findings in both clinical and basic sciences as they are relevant to head and neck cancer. These findings have recently enhanced our understanding of head and neck carcinogenesis at the genetic and molecular levels, offering the promise of improved preventive and therapeutic strategies. This book will also present information on the important clinical advances that have been made in chemoprevention, organ preservation, and the simultaneous use of chemo therapy and radiotherapy. The first part provides an overview of the etiology and biology of head and neck cancer, including an examination of human papillomaviruses in both benign and malignant lesions. This section also discusses the carcinogenic process at the genetic and molecular levels, as well as aberrant squamous differentiation; increased understanding of these areas has great potential to translate into new strategies for cancer prevention. The second part describes recent advances in developing a risk model for head and neck cancer, as well as the application of genetic susceptibility data in chemoprevention. This section also includes overviews of the status of chemoprevention trials and of the process of invasion and metastasis in head and neck cancer.
Author : James A. Radosevich Publisher : Springer Science & Business Media Page : 1070 pages File Size : 52,8 Mb Release : 2013-05-24 Category : Medical ISBN : 9789400758278
Head & Neck Cancer: Current Perspectives, Advances, and Challenges by James A. Radosevich Pdf
This is a nearly complete collection of Chapters that provide an up to date overview of all aspects of Head and Neck cancer. It is written by professionals but is not only intended for other professionals, but students, patients, policy makers, etc. There are so many aspects to this group of diseases that even the most seasoned professional will learn something from having read this book.
Intensity Modulated Radiation Therapy for Head and Neck Cancer by K. S. Clifford Chao,Gokhan Ozyigit Pdf
The first clinical book on the hottest topic in radiation oncology, this timely teaching text offers step-by-step guidance in use of IMRT for cancers at each subsite of the head and neck. The book's high-end content gives readers the clinical decision-making expertise and technical proficiency to incorporate this state-of-the-art radiation treatment technique into practice. Unique to this text is the site-specific instruction on target determination and delineation, to ensure adequate treatment of the tumor target while sparing adjacent normal tissue. More than 250 detailed full-color and black-and-white illustrations clarify each step in clinical implementations of head and neck cancer treatment, especially IMRT. The book provides a concise, pertinent overview of the natural course, lymph node spread, diagnostic criteria, and therapeutic options for each head and neck cancer subsite. Numerous tables provide extensive summaries of the IMRT literature. Figures with succinct explanatory text demonstrate the patterns of direct tumor extension and nodal metastasis with which target volumes are determined and delineated. Clinical outcomes for patients treated with IMRT and with conventional techniques are also included.
Head and Neck Cancer by Bruce Brockstein,Gregory Masters Pdf
Exciting advances are occurring in the understanding of the molecular pathogenesis of squamous head and neck cancers. Epidemiology, staging and screening, as well as premalignancy, chemoprevention and the molecular biology of head and neck cancer, lay the groundwork for the understanding of the clinical chapters that follow. Controversial treatments will be compared to the standard management of patient care. Therapy chapters are divided into stage or category specific (resectable advanced, unresectable advanced or metastatic) problems, allowing the reader to review the current standards and options for patient types or specific patients easily. Considerations of supportive care, late toxicities and quality of life, often overlooked are reviewed in detail. This is a comprehensive summary of the current state of the art research and treatment.