Methods And Applications Of Cycloaddition Reactions In Organic Syntheses

Author : Nagatoshi Nishiwaki
Publisher : John Wiley & Sons
Page : 996 pages
File Size : 45,5 Mb
Release : 2013-12-17
Category : Science
ISBN : 9781118778203

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Methods and Applications of Cycloaddition Reactions in Organic Syntheses by Nagatoshi Nishiwaki Pdf

Advanced tools for developing new functional materials and applications in chemical research, pharmaceuticals, and materials science Cycloadditions are among the most useful tools for organic chemists, enabling them to build carbocyclic and heterocyclic structures. These structures can then be used to develop a broad range of functional materials, including pharmaceuticals, agrochemicals, dyes, and optics. With contributions from an international team of leading experts and pioneers in cycloaddition chemistry, this book brings together and reviews recent advances, trends, and emerging research in the field. Methods and Applications of Cycloaddition Reactions in Organic Syntheses focuses on two component cycloadditions, with chapters covering such topics as: N1 unit transfer reaction to C–C double bonds [3+2] Cycloaddition of α, β-unsaturated metal-carbene complexes Formal [3+3] cycloaddition approach to natural product synthesis Development of new methods for the construction of heterocycles based on cycloaddition reaction of 1,3-dipoles Cycloreversion approach for preparation of large π-conjugated compounds Transition metal-catalyzed or mediated [5+1] cycloadditions Readers will learn methods for seamlessly executing important reactions such as Diels-Alder and stereoselective dipolar reactions in order to fabricate heterocyclic compounds, natural products, and functional molecules. The book not only features cutting-edge topics, but also important background information, such as the contributors’ process for developing new methodologies, to help novices become fully adept in the field. References at the end of each chapter lead to original research papers and reviews for facilitating further investigation of individual topics. Covering the state of the science and technology, Methods and Applications of Cycloaddition Reactions in Organic Syntheses enables synthetic organic chemists to advance their research and develop new functional materials and applications in chemical research, pharmaceuticals, and materials science.

Author : Shu Kobayashi,Karl Anker Jørgensen
Publisher : John Wiley & Sons
Page : 354 pages
File Size : 47,7 Mb
Release : 2002
Category : Science
ISBN : 3527301593

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Cycloaddition Reactions in Organic Synthesis by Shu Kobayashi,Karl Anker Jørgensen Pdf

During the miners' strike in the 1980s, a worker is killed in the striking coalfields of Wales. Some months later, a government minister thought to be connected with the death is also shot. Lewis Redfern—once a radical but now a political analyst and journalist—pursues the sniper, a lonely hunt that leads him through an imbroglio of civil service leaks to a secret organization: a source of insurrection far more powerful than anyone could have suspected known as the Volunteers. In this fast-paced narrative of espionage and intrigue, Redfern, through his obsessive pursuit of justice, finally encounters the truth about himself as the novel discusses the conflict between moral choice and political loyalty.

Author : W. Carruthers
Publisher : Elsevier Science & Technology
Page : 388 pages
File Size : 45,6 Mb
Release : 1990
Category : Organic compounds
ISBN : UOM:39076001677439

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Cycloaddition Reactions in Organic Synthesis by W. Carruthers Pdf

Paperback. Demonstrates the wide scope of cycloaddition reactions, including the Diels-Alder reaction, the ene reaction, 1,3-dipolar cycloadditions and [2]2] cycloadditions in organic synthesis. The author, a leading exponent of the subject, illustrates the ways in which they can be employed in the synthesis of a wide range of carbocyclic and heterocyclic compounds, including a variety of natural products of various types. Special attention is given to intramolecular reactions, which often provide a rapid and efficient route to polycyclic compounds, and to the stereochemistry of the reactions, including recent and developing work on enantioselective synthesis.

Author : Albert Padwa,William H. Pearson
Publisher : John Wiley & Sons
Page : 962 pages
File Size : 42,7 Mb
Release : 2002-11-01
Category : Science
ISBN : 9780471280613

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Synthetic Applications of 1,3-Dipolar Cycloaddition Chemistry Toward Heterocycles and Natural Products, Volume 59 by Albert Padwa,William H. Pearson Pdf

Dipolar cycloaddition reactions have found many useful applications in chemistry, particularly with respect to the synthesis of compounds with new chiral centers. Synthetic Applications of 1,3-Dipolar Cycloaddition Chemistry Toward Heterocycles and Natural Products updates the popular 1984 edition, featuring the advances made over the past twenty years and focusing on synthetic applications.

Author : William Carruthers
Publisher : Unknown
Page : 373 pages
File Size : 40,6 Mb
Release : 1990
Category : Electronic
ISBN : OCLC:908946372

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CYCLOADDITION REACTIONS IN ORGANIC SYNTHESIS by William Carruthers Pdf

Author : Francesco Fringuelli,Aldo Taticchi
Publisher : John Wiley & Sons
Page : 364 pages
File Size : 44,5 Mb
Release : 2002-01-21
Category : Science
ISBN : 047180343X

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The Diels-Alder Reaction by Francesco Fringuelli,Aldo Taticchi Pdf

70 Jahre Forschung an der Diels-Alder-Reaktion: Dieses Buch fasst die wichtigsten und beeindruckendsten Ergebnisse in einzigartiger Weise zusammen! Zunächst werden die Grundprinzipien der Reaktion klar und verständlich anhand übersichtlicher Graphiken erläutert. Spezielle Vorschriften und gegebenenfalls ihre industrielle Umsetzung werden anschließend erklärt. Einen Schwerpunkt bilden auch physikalische und katalytische Verfahren zur Steigerung der Selektivität der Reaktion. Cycloadditionen in konventionellen und unkonventionellen Medien werden vorgestellt. Mit über 1.000 Literaturverweisen!

Author : Albert Padwa,William H. Pearson
Publisher : Wiley-Interscience
Page : 0 pages
File Size : 41,9 Mb
Release : 2002-04-19
Category : Science
ISBN : 0471387266

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The Chemistry of Heterocyclic Compounds, Synthetic Applications of 1,3-Dipolar Cycloaddition Chemistry Toward Heterocycles and Natural Products by Albert Padwa,William H. Pearson Pdf

Dipolar cycloaddition reactions have found many useful applications in chemistry, particularly with respect to the synthesis of compounds with new chiral centers. Synthetic Applications of 1,3-Dipolar Cycloaddition Chemistry Toward Heterocycles and Natural Products updates the popular 1984 edition, featuring the advances made over the past twenty years and focusing on synthetic applications.

Author : Marko Hapke,Gerhard Hilt
Publisher : John Wiley & Sons
Page : 480 pages
File Size : 52,9 Mb
Release : 2020-04-06
Category : Technology & Engineering
ISBN : 9783527344505

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Cobalt Catalysis in Organic Synthesis by Marko Hapke,Gerhard Hilt Pdf

Provides a much-needed account of the formidable "cobalt rush" in organic synthesis and catalysis Over the past few decades, cobalt has turned into one of the most promising metals for use in catalytic reactions, with important applications in the efficient and selective synthesis of natural products, pharmaceuticals, and new materials. Cobalt Catalysis in Organic Synthesis: Methods and Reactions provides a unique overview of cobalt-catalysed and -mediated reactions applied in modern organic synthesis. It covers a broad range of homogeneous reactions, like cobalt-catalysed hydrogenation, hydrofunctionalization, cycloaddition reactions, C-H functionalization, as well as radical and biomimetic reactions. First comprehensive book on this rapidly evolving research area Covers a broad range of homogeneous reactions, such as C-H activation, cross-coupling, synthesis of heterocyclic compounds (Pauson-Khand), and more Chapters on low-valent cobalt complexes as catalysts in coupling reactions, and enantioselective cobalt-catalyzed transformations are also included Can be used as a supplementary reader in courses of advanced organic synthesis and organometallic chemistry Cobalt Catalysis in Organic Synthesis is an ideal book for graduates and researchers in academia and industry working in the field of synthetic organic chemistry, catalysis, organometallic chemistry, and natural product synthesis.

Author : Oleg G. Kulinkovich
Publisher : John Wiley & Sons
Page : 432 pages
File Size : 54,9 Mb
Release : 2015-09-30
Category : Science
ISBN : 9781118978405

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Cyclopropanes in Organic Synthesis by Oleg G. Kulinkovich Pdf

This is a practical guidebook about cyclopropanes that thoroughly surveys derivatives and transformations, synthetic methods, and experimental efficiency as a gateway for further research and development in the field. • Provides comprehensive lists and synthetically-oriented synopses of cyclopropane chemistry review references along with publication data on applications in the syntheses of natural and related biologically active compounds • Acts as a resource to help readers better understand cyclopropane applications for the efficient realization of synthetically important organic transformations and popular experimental procedures • Includes new developments and up-to-date information that will lead to original methodologies for complex organic synthesis • Stresses universality, flexibility, and experimental efficiency of a strategy based on preparing cyclopropane derivatives and performing ring cleavage reactions with inexpensive reagents • Focuses on the synthetic potential of cyclopropane applications, for example the synthesis of natural compounds and other target-oriented syntheses via cyclopropane intermediaries, as well on their planning by retrosynthetic analysis

Author : Pierre Vogel,Kendall N. Houk
Publisher : John Wiley & Sons
Page : 1382 pages
File Size : 43,7 Mb
Release : 2019-10-07
Category : Science
ISBN : 9783527345328

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Organic Chemistry by Pierre Vogel,Kendall N. Houk Pdf

Provides the background, tools, and models required to understand organic synthesis and plan chemical reactions more efficiently Knowledge of physical chemistry is essential for achieving successful chemical reactions in organic chemistry. Chemists must be competent in a range of areas to understand organic synthesis. Organic Chemistry provides the methods, models, and tools necessary to fully comprehend organic reactions. Written by two internationally recognized experts in the field, this much-needed textbook fills a gap in current literature on physical organic chemistry. Rigorous yet straightforward chapters first examine chemical equilibria, thermodynamics, reaction rates and mechanisms, and molecular orbital theory, providing readers with a strong foundation in physical organic chemistry. Subsequent chapters demonstrate various reactions involving organic, organometallic, and biochemical reactants and catalysts. Throughout the text, numerous questions and exercises, over 800 in total, help readers strengthen their comprehension of the subject and highlight key points of learning. The companion Organic Chemistry Workbook contains complete references and answers to every question in this text. A much-needed resource for students and working chemists alike, this text: -Presents models that establish if a reaction is possible, estimate how long it will take, and determine its properties -Describes reactions with broad practical value in synthesis and biology, such as C-C-coupling reactions, pericyclic reactions, and catalytic reactions -Enables readers to plan chemical reactions more efficiently -Features clear illustrations, figures, and tables -With a Foreword by Nobel Prize Laureate Robert H. Grubbs Organic Chemistry: Theory, Reactivity, and Mechanisms in Modern Synthesis is an ideal textbook for students and instructors of chemistry, and a valuable work of reference for organic chemists, physical chemists, and chemical engineers.

Author : Patrick H. Toy,Yulin Lam
Publisher : John Wiley & Sons
Page : 560 pages
File Size : 54,5 Mb
Release : 2012-01-18
Category : Science
ISBN : 9780470599143

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Solid-Phase Organic Synthesis by Patrick H. Toy,Yulin Lam Pdf

Presents both the fundamental concepts and the most recent applications in solid-phase organic synthesis With its emphasis on basic concepts, Solid-Phase Organic Synthesis guides readers through all the steps needed to design and perform successful solid-phase organic syntheses. The authors focus on the fundamentals of heterogeneous supports in the synthesis of organic molecules, explaining the use of a solid material to facilitate organic synthesis. This comprehensive text not only presents the fundamentals, but also reviews the most recent research findings and applications, offering readers everything needed to conduct their own state-of-the-art science experiments. Featuring chapters written by leading researchers in the field, Solid-Phase Organic Synthesis is divided into two parts: Part One, Concepts and Strategies, discusses the linker groups used to attach the synthesis substrate to the solid support, colorimetric tests to identify the presence of functional groups, combinatorial synthesis, and diversity-oriented synthesis. Readers will discover how solid-phase synthesis is currently used to facilitate the discovery of new molecular functionality. The final chapter discusses how using a support can change or increase reaction selectivity. Part Two, Applications, presents examples of the solid-phase synthesis of various classes of organic molecules. Chapters explore general asymmetric synthesis on a support, strategies for heterocyclic synthesis, and synthesis of radioactive organic molecules, dyes, dendrimers, and oligosaccharides. Each chapter ends with a set of conclusions that underscore the key concepts and methods. References in each chapter enable readers to investigate any topic in greater depth. With its presentation of basic concepts as well as recent findings and applications, Solid-Phase Organic Synthesis is the ideal starting point for students and researchers in organic, medicinal, and combinatorial chemistry who want to take full advantage of current solid-phase synthesis techniques.

Author : Irina A. Maretina
Publisher : John Wiley & Sons
Page : 357 pages
File Size : 54,7 Mb
Release : 2013-10-08
Category : Science
ISBN : 9781118709290

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Alkynes in Cycloadditions by Irina A. Maretina Pdf

Acetylene systems present a new route to cyclic compounds as an alternative to more traditional methods employed in classical organic chemistry. The synthesis of cyclic structures based on acetylene systems has important applications in the formation of nanostructures, naturally occurring compounds and chemosensory materials for the design of nonlinear optics, electronic and photonic devices. Alkynes in Cycloadditions presents a modern review of regioselective synthesis of aromatic and non-aromatic carbocyclic and heterocyclic ring systems based primarily on [2+2+2] and [4+2] cycloadditions, and other reactions of acetylenic units including enediynes and enyne-allenes. Topics covered include: New strategies for the formation of aromatic and polynuclear hydrocarbons based on (Z)-hex-3-en-1,5-diyne and (Z)-hepta-1,2,4-triene-6-yne blocks. One-step synthesis of benzene derivatives, β-substituted naphthalenes and acenes by the cycloaromatization of enediynes and enyne-allenes by Bergman, Myers-Saito and Shmittel. Mechanisms of cycloaromatization resulting in the formation of fulvene and indene systems. Heterocyclization involving enyne-carbodiimides. New achievements in classical cycloaddition reactions such as the Diels-Alder condensation with acetylenic dienophiles and [2+2] cycloadditions with acetylene components Alkynes in Cycloadditions presents a comprehensive summary of the literature on methods for the synthesis of ring systems from acetylenes for academic researchers working in the fields of organic synthesis, physical organic chemistry, organometallic chemistry, catalysis, materials science, nanomaterials and biochemistry.

Author : Laszlo Kurti,Barbara Czako
Publisher : Elsevier
Page : 808 pages
File Size : 43,9 Mb
Release : 2005-04-29
Category : Science
ISBN : 9780080575414

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Strategic Applications of Named Reactions in Organic Synthesis by Laszlo Kurti,Barbara Czako Pdf

Kurti and Czako have produced an indispensable tool for specialists and non-specialists in organic chemistry. This innovative reference work includes 250 organic reactions and their strategic use in the synthesis of complex natural and unnatural products. Reactions are thoroughly discussed in a convenient, two-page layout--using full color. Its comprehensive coverage, superb organization, quality of presentation, and wealth of references, make this a necessity for every organic chemist. * The first reference work on named reactions to present colored schemes for easier understanding* 250 frequently used named reactions are presented in a convenient two-page layout with numerous examples* An opening list of abbreviations includes both structures and chemical names * Contains more than 10,000 references grouped by seminal papers, reviews, modifications, and theoretical works * Appendices list reactions in order of discovery, group by contemporary usage, and provide additional study tools* Extensive index quickly locates information using words found in text and drawings

Author : Jan Hamer
Publisher : Elsevier
Page : 513 pages
File Size : 50,5 Mb
Release : 2013-07-19
Category : Science
ISBN : 9780323163118

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1,4-Cycloaddition Reaction: The Diels-Alder Reaction in Heterocyclic Syntheses by Jan Hamer Pdf

Organic Chemistry, Volume 8: 1,4-Cycloaddition Reactions: The Diels-Alder Reaction in Heterocyclic Syntheses describes 1,4-cycloaddition reactions leading to the formation of five- or six-membered heterocyclic compounds. Divided into 13 chapters, this book starts with an overview of various 1,4-cycloaddition reaction equations in the presence of at least one atom other than carbon. The following chapters describe the reaction mechanisms of five- or six-membered ring formed upon reaction with a dienophile, which contains an atom other than carbon. Considerable chapters are devoted to compounds used as dienophiles, including trivalent phosphorus, cyanogens and cyanogens-like compounds, imino, azo, carbonyl, thiocarbonyl, and diene compounds, as well as oxygen. Other chapters highlight some 1,4-cycloaddition reactions taking place through free radical intermediates. This book is of value to organic and research chemists, as well as undergraduate and graduate organic chemistry students.

Author : W Carruthers,Iain Coldham
Publisher : Cambridge University Press
Page : 506 pages
File Size : 40,9 Mb
Release : 2015-04-10
Category : Science
ISBN : 9781107567450

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Modern Methods of Organic Synthesis South Asia Edition by W Carruthers,Iain Coldham Pdf

Textbook on modern methods of organic synthesis.