Microcirculation Imaging

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Microcirculation Imaging

Author : Martin J. Leahy
Publisher : John Wiley & Sons
Page : 413 pages
File Size : 52,5 Mb
Release : 2012-07-10
Category : Medical
ISBN : 9783527328949

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Microcirculation Imaging by Martin J. Leahy Pdf

Adopting a multidisciplinary approach with input from physicists, researchers and medical professionals, this is the first book to introduce many different technical approaches for the visualization of microcirculation, including laser Doppler and laser speckle, optical coherence tomography and photo-acoustic tomography. It covers everything from basic research to medical applications, providing the technical details while also outlining the respective strengths and weaknesses of each imaging technique. Edited by an international team of top experts, this is the ultimate handbook for every clinician and researcher relying on microcirculation imaging.

Intravital Microcirculation Imaging

Author : Christian Lehmann
Publisher : Unknown
Page : 120 pages
File Size : 41,8 Mb
Release : 2013-01-01
Category : Electronic
ISBN : 3899677862

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Intravital Microcirculation Imaging by Christian Lehmann Pdf

Orthogonal Polarization Spectral Imaging

Author : K. Messmer
Publisher : Karger Medical and Scientific Publishers
Page : 132 pages
File Size : 44,6 Mb
Release : 2000-01-01
Category : Science
ISBN : 9783805570657

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Orthogonal Polarization Spectral Imaging by K. Messmer Pdf

This book introduces orthogonal polarized spectral (OPS) imaging, a new technique for examining the microcirculation in both animals and humans during surgery and in other clinical setups. OPS imaging creates an image by using the sub-surface scattering of polarized light to create a 'virtual' light source within the tissue being observed. Thus, the microcirculation can be visualized without the use of fluorescent dyes or transillumination, making it possible to observe the human microcirculation in real time. The technology has been incorporated into a small, hand-held device called a CYTOSCANTM video microscope, which can be used in both research and clinical settings. Several validation studies comparing OPS imaging against standard intravital fluorescence microscopy in animal models demonstrate that it is possible to make quantitative measurements of relevant parameters (vessel diameter, red blood cell velocity and functional capillary density) from these images. Further studies show the feasibility of making such measurements in various human organs such as the skin, intestine, and brain. In addition, this book presents several clinical applications including use in cardiopulmonary bypass, neurosurgery, intensive care, general surgery and plastic surgery. The book should be read by anyone concerned with microvascular perfusion. This includes not only those involved in microcirculation research but clinicians interested in nutritive perfusion. The technique described here will be of aid to a variety of surgical specialists from cardiac and neurosurgeons to plastic surgeons. It will likewise be of interest to angiologists, anesthesiologists, neonatologists, dermatologists, and general surgeons.

Physiological Assessment of Coronary Stenoses and the Microcirculation

Author : Javier Escaned,Justin Davies
Publisher : Springer
Page : 313 pages
File Size : 49,9 Mb
Release : 2017-08-10
Category : Medical
ISBN : 9781447152453

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Physiological Assessment of Coronary Stenoses and the Microcirculation by Javier Escaned,Justin Davies Pdf

​Since the introduction of coronary angiography, a key technique in understanding coronary artery disease, a number of paradigms regarding its study and interpretation have taken place. Following an emphasis on improved angiographic and subsequent intracoronary imaging techniques, functional assessment of coronary circulation has demonstrated to have major implications for diagnosis and treatment of coronary artery disease. Fractional flow reserve, a pressure derived index of stenosis severity, constitutes the best example of the current importance of physiological assessment in clinical practice. However, the acceptance of FFR by cardiologists contrasts with important voids in knowledge on the basic principles of coronary physiology and of other available techniques that, as an alternative to FFR, allow a more comprehensive assessment of coronary circulation. This is particularly noticeable in the assessment of microcirculation, an unavoidable compartment of coronary circulation that is frequently affected in acute coronary syndromes of in the presence of cardiovascular risk factors or non-coronary heart disease. A deeper understanding of the relationship between epicardial vessel and microcirculatory involvement has started with the advent of newer imaging techniques like invasive optical coherence tomography, and non-invasive CT and NMR techniques. This book aims to be an indispensable tool for clinicians and researches in the field of coronary artery disease. It provides a balanced, comprehensive review of anatomy, physiology and available techniques, discusses both the diagnosis of epicardial vessel and microcirculatory disease, the impact of different diseases at different levels of coronary circulation, and the best way to address a separate or combined assessment of different levels of coronary circulation. ​

Orthogonal Polarization Spectral Imaging

Author : K. Messmer
Publisher : Unknown
Page : 0 pages
File Size : 41,6 Mb
Release : 2000
Category : Medical
ISBN : 3318005703

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Orthogonal Polarization Spectral Imaging by K. Messmer Pdf

This book introduces orthogonal polarized spectral (OPS) imaging, a new technique for examining the microcirculation in both animals and humans during surgery and in other clinical setups. OPS imaging creates an image by using the sub-surface scattering of polarized light to create a 'virtual' light source within the tissue being observed. Thus, the microcirculation can be visualized without the use of fluorescent dyes or transillumination, making it possible to observe the human microcirculation in real time. The technology has been incorporated into a small, hand-held device called a CYTOSCANTM video microscope, which can be used in both research and clinical settings. Several validation studies comparing OPS imaging against standard intravital fluorescence microscopy in animal models demonstrate that it is possible to make quantitative measurements of relevant parameters (vessel diameter, red blood cell velocity and functional capillary density) from these images. Further studies show the feasibility of making such measurements in various human organs such as the skin, intestine, and brain. In addition, this book presents several clinical applications including use in cardiopulmonary bypass, neurosurgery, intensive care, general surgery and plastic surgery. The book should be read by anyone concerned with microvascular perfusion. This includes not only those involved in microcirculation research but clinicians interested in nutritive perfusion. The technique described here will be of aid to a variety of surgical specialists from cardiac and neurosurgeons to plastic surgeons. It will likewise be of interest to angiologists, anesthesiologists, neonatologists, dermatologists, and general surgeons.

In Vivo Optical Imaging of Brain Function, Second Edition

Author : Ron D. Frostig
Publisher : CRC Press
Page : 428 pages
File Size : 54,9 Mb
Release : 2009-05-06
Category : Science
ISBN : 9781420076851

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In Vivo Optical Imaging of Brain Function, Second Edition by Ron D. Frostig Pdf

These are exciting times for the field of optical imaging of brain function. Rapid developments in theory and technology continue to considerably advance understanding of brain function. Reflecting changes in the field during the past five years, the second edition of In Vivo Optical Imaging of Brain Function describes state-of-the-art techniques and their applications for the growing field of functional imaging in the live brain using optical imaging techniques. New in the Second Edition: Voltage-sensitive dyes imaging in awake behaving animals Imaging based on genetically encoded probes Imaging of mitochondrial auto-fluorescence as a tool for cortical mapping Using pH-sensitive dyes for functional mapping Modulated imaging Calcium imaging of neuronal activity using 2-photon microscopy Fourier approach to optical imaging Fully updated chapters from the first edition Leading Authorities Explore the Latest Techniques Updated to reflect continuous development in this emerging research area, this new edition, as with the original, reaches across disciplines to review a variety of non-invasive optical techniques used to study activity in the living brain. Leading authorities from such diverse areas as biophysics, neuroscience, and cognitive science present a host of perspectives that range from a single neuron to large assemblies of millions of neurons, captured at various temporal and spatial resolutions. Introducing techniques that were not available just a few years ago, the authors describe the theory, setup, analytical methods, and examples that highlight the advantages of each particular method.

Computational Biology for Stem Cell Research

Author : Pawan Raghav,Rajesh Kumar,Anjali Lathwal,Navneet Sharma
Publisher : Elsevier
Page : 568 pages
File Size : 54,7 Mb
Release : 2024-01-12
Category : Science
ISBN : 9780443132216

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Computational Biology for Stem Cell Research by Pawan Raghav,Rajesh Kumar,Anjali Lathwal,Navneet Sharma Pdf

Computational Biology for Stem Cell Research is an invaluable guide for researchers as they explore HSCs and MSCs in computational biology. With the growing advancement of technology in the field of biomedical sciences, computational approaches have reduced the financial and experimental burden of the experimental process. In the shortest span, it has established itself as an integral component of any biological research activity. HSC informatics (in silico) techniques such as machine learning, genome network analysis, data mining, complex genome structures, docking, system biology, mathematical modeling, programming (R, Python, Perl, etc.) help to analyze, visualize, network constructions, and protein-ligand or protein-protein interactions. This book is aimed at beginners with an exact correlation between the biomedical sciences and in silico computational methods for HSCs transplantation and translational research and provides insights into methods targeting HSCs properties like proliferation, self-renewal, differentiation, and apoptosis. Modeling Stem Cell Behavior: Explore stem cell behavior through animal models, bridging laboratory studies to real-world clinical allogeneic HSC transplantation (HSCT) scenarios. Bioinformatics-Driven Translational Research: Navigate a path from bench to bedside with cutting-edge bioinformatics approaches, translating computational insights into tangible advancements in stem cell research and medical applications. Interdisciplinary Resource: Discover a single comprehensive resource catering to biomedical sciences, life sciences, and chemistry fields, offering essential insights into computational tools vital for modern research.

Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Oncology

Author : Alan Jackson,David L. Buckley,Geoffrey J. M. Parker
Publisher : Springer Science & Business Media
Page : 311 pages
File Size : 46,8 Mb
Release : 2006-03-30
Category : Medical
ISBN : 9783540264200

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Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Oncology by Alan Jackson,David L. Buckley,Geoffrey J. M. Parker Pdf

Dynamic contrast-enhanced MRI is now established as the methodology of choice for the assessment of tumor microcirculation in vivo. The method assists clinical practitioners in the management of patients with solid tumors and is finding prominence in the assessment of tumor treatments, including anti-angiogenics, chemotherapy, and radiotherapy. Here, leading authorities discuss the principles of the methods, their practical implementation, and their application to specific tumor types. The text is an invaluable single-volume reference that covers all the latest developments in contrast-enhanced oncological MRI.

World Congress on Medical Physics and Biomedical Engineering May 26-31, 2012, Beijing, China

Author : Mian Long
Publisher : Springer Science & Business Media
Page : 2345 pages
File Size : 44,6 Mb
Release : 2013-02-11
Category : Technology & Engineering
ISBN : 9783642293054

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World Congress on Medical Physics and Biomedical Engineering May 26-31, 2012, Beijing, China by Mian Long Pdf

The congress’s unique structure represents the two dimensions of technology and medicine: 13 themes on science and medical technologies intersect with five challenging main topics of medicine to create a maximum of synergy and integration of aspects on research, development and application. Each of the congress themes was chaired by two leading experts. The themes address specific topics of medicine and technology that provide multiple and excellent opportunities for exchanges.

Microcirculation Revisited

Author : Helena Lenasi
Publisher : BoD – Books on Demand
Page : 288 pages
File Size : 44,6 Mb
Release : 2016-10-26
Category : Medical
ISBN : 9789535127307

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Microcirculation Revisited by Helena Lenasi Pdf

The book provides a comprehensive overview of selected topics in microcirculation, from physiology to pathophysiology including molecular mechanisms and clinical aspects. It contains 10 chapters written by reputed authors, which comprehensively sum up the current knowledge and some interesting new insights in the field of microcirculation. It will be useful to a broad range of audience, from students to highly profiled experts, helping them to expand their knowledge on microcirculation and opening up additional questions for further investigation.

Advances in Molecular Biophotonics

Author : Yong Deng,Zhenli Huang,Yu Li,Da Xing,Zhihong Zhang
Publisher : Walter de Gruyter GmbH & Co KG
Page : 492 pages
File Size : 53,5 Mb
Release : 2017-04-24
Category : Science
ISBN : 9783110388039

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Advances in Molecular Biophotonics by Yong Deng,Zhenli Huang,Yu Li,Da Xing,Zhihong Zhang Pdf

Presents recent developments and application of fluorescent protein-labelling techniques and two-photon molecular probes. Introduces the theoretical and experimental researches of super-resolution localization microscopy, photoacoustic molecular (functional) imaging, and optical molecular tomography for small animal in vivo. Illustrates optical labeling techniques and imaging instruments and their application in biological studies. Suits well for researchers and graduates in biomolecular photonics fields.

Coronary Imaging and Physiology

Author : Myeong-Ki Hong
Publisher : Springer
Page : 331 pages
File Size : 48,8 Mb
Release : 2017-10-31
Category : Medical
ISBN : 9789811027871

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Coronary Imaging and Physiology by Myeong-Ki Hong Pdf

This book is intended as a guide for all cardiologists who are interested in coronary imaging and physiology, a sound understanding of which is vital for the optimal performance of appropriate coronary interventions. The basics of each relevant modality are presented, with clear explanation of clinical utility and evaluation of the evidence regarding clinical outcomes. All technical methods are described in detail, and the text is complemented by numerous helpful tables and illustrations. The effectiveness of intravascular coronary imaging in improving clinical outcomes is proven, and it is widely used for this purpose. Two modalities for intravascular coronary imaging are available in clinical practice: intravascular ultrasound (IVUS) and optical coherence tomography (OCT). For coronary physiology, the pressure wire-derived fractional flow reserve (FFR) provides information on the functional status of coronary trees. This technique and its clinical applications receive particular attention in the book, which also looks beyond FFR to FFR-CT, a method using computational fluid dynamics, and to invasive assessment of the microcirculation.

Handbook of Biophotonics

Author : Jürgen Popp,Valery V. Tuchin,Arthur Chiou,Stefan H. Heinemann
Publisher : John Wiley & Sons
Page : 1187 pages
File Size : 49,7 Mb
Release : 2011-11-30
Category : Science
ISBN : 9783527410484

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Handbook of Biophotonics by Jürgen Popp,Valery V. Tuchin,Arthur Chiou,Stefan H. Heinemann Pdf

This new handbook covers the world of biophotonics not only geographically -- with the editors coming from different continents -- but also in terms of content, since the authors come from the whole spectrum of biophotonic basic and applied research. Designed to set the standard for the scientific community, these three volumes break new ground by providing readers with the physics basics as well as the biological and medical background, together with detailed reports on recent technical advances. The Handbook also adopts an application-related approach, starting with the application and then citing the various tools to solve the scientific task, making it of particular value to medical doctors. Divided into several sections, the first part offers introductory chapters on the different fields of research, with subsequent parts focusing on the applications and techniques in various fields of industry and research. The result is a handy source for scientists seeking the basics in a condensed form, and equally a reference for quickly gathering the knowledge from neighboring disciplines. Absolutely invaluable for biophotonic scientists in their daily work.

Annual Update in Intensive Care and Emergency Medicine 2014

Author : Jean-Louis Vincent
Publisher : Springer Science & Business Media
Page : 796 pages
File Size : 48,5 Mb
Release : 2014-02-06
Category : Medical
ISBN : 9783319037462

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Annual Update in Intensive Care and Emergency Medicine 2014 by Jean-Louis Vincent Pdf

The Yearbook compiles the most recent developments in experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in the field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.