Microcirculation In Cardiovascular Diseases

Author : Enrico Agabiti-Rosei,Anthony M. Heagerty,Damiano Rizzoni
Publisher : Springer Nature
Page : 215 pages
File Size : 55,9 Mb
Release : 2020-10-03
Category : Medical
ISBN : 9783030478018

Get Book

Microcirculation in Cardiovascular Diseases by Enrico Agabiti-Rosei,Anthony M. Heagerty,Damiano Rizzoni Pdf

This book offers an extensive review of the most recent data on the pathophysiological role of structural and functional alterations in the microcirculation, particularly focusing on hypertension and diabetes. It covers several relevant and innovative aspects, including the possible mechanisms involved in the development of microvascular remodeling and rarefaction, the technical approaches available for the detection of microvascular alterations, including non-invasive evaluations, the prognostic role of changes in small resistance artery structure, the possibility of preventing or regressing such alterations with appropriate treatment, and the potential clinical advantages of such intervention. A number of innovative areas of research are considered, including the role of the immune system, inflammation and oxidative stress in the development of microvascular alterations. Lastly, it examines the availability of recent non-invasive methods for the evaluation of small resistance artery morphology in the retina, which in the near future may provide a useful tool for the stratification of cardiovascular risk and even for clinical decisions regarding drug treatment, thus providing physicians with a clinically relevant instrument for improving and optimizing the management of hypertensive and diabetic patients. The book provides valuable, clinically relevant information for specialists (cardiology, internal medicine, and endocrinology) and general practitioners, and also offers novel and stimulating data to basic and clinical researchers.

Author : Maria Dorobantu,Lina Badimon
Publisher : Springer Nature
Page : 298 pages
File Size : 44,7 Mb
Release : 2019-11-04
Category : Medical
ISBN : 9783030281991

Get Book

Microcirculation by Maria Dorobantu,Lina Badimon Pdf

This comprehensive reference book of coronary microcirculation broadly covers theoretical aspects, clinical cases and therapeutic considerations from an innovative perspective. Topics covered include: ischemic heart disease, silent cerebral damage, heart failure, left ventricular hypertrophy arrhythmias, and cerebral and renal microcirculation. Microcirculation: From Bench to Bedside underlines the clinical importance of addressing coronary microcirculation with relevant clinical examples that are often encountered by practitioners. It therefore provides a critical resource on microcirculation for both specialist and non-specialist practitioners.

Author : Hisao Manabe,Benjamin W. Zweifach,Konrad Messmer
Publisher : Springer Science & Business Media
Page : 551 pages
File Size : 42,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9784431680789

Get Book

Microcirculation in Circulatory Disorders by Hisao Manabe,Benjamin W. Zweifach,Konrad Messmer Pdf

This book presents recent progress in microvascular disorders including cerebral, myocardial and peripheral tissue ischemia, multiple organ failure and gastroenterological disorders. Knowledge of microcirculation is essential in order to understand thoroughly the mechanism of organ disorders. This book successfully elucidates the pathophysiologic significance of microcirculation in ischemia and other diseases. It is useful for basic researchers and clinicians who are interested in the early diagnosis and prevention of cardiovascular diseases as well as in the mechanism of circulatory disorders.

Author : H. Tillmanns,W. Kübler,H. Zebe
Publisher : Springer Science & Business Media
Page : 356 pages
File Size : 46,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642684852

Get Book

Microcirculation of the Heart by H. Tillmanns,W. Kübler,H. Zebe Pdf

Microcirculation is a rather new field which has been of predominant interest to basic scientists, linking togeth~r technical, hemodynamic, and biochemical aspects. The fmdings elaborated, however, are not only of theoretical interest, but bear in addition great clinical implications. In clinical cardiology this became quite evident by the use of tracers in order to study myocardial perfuSion and by the deSCription of certain clinical entities - such as angina with normal coro nary arteries - which are best explained by "disturbed microcirculation". With respect to this new developing theoretical and clinical field of cardiac microcirculation it was the aim of the Microcirculation Working Group of the European Society of Cardiology to have a symposium on which all different but clinically relevant aspects of cardiac microcirculation will be covered. This symposium, held in Heidelberg in January 1980, was planned not only for the exchange of concepts and ideas, but was expected to be in addition partially a teaching session; the basic scientists should be directed toward a better under standing of the clinical problems, and the clinicians should learn more about the basic mechanisms regulating substrate and ion exchange in such an impor tant organ as the heart, and furthermore the theoretical limitations of some of the diagnostic and therapeutical procedures should be taught. Without a lot of help we would never have succeeded in organizing the sym posium and editing its results.

Author : Kaneez Fatima Shad,Nazar Luqman,Seyed Soheil Saeedi Saravi
Publisher : BoD – Books on Demand
Page : 168 pages
File Size : 46,8 Mb
Release : 2020-07-22
Category : Medical
ISBN : 9781789855517

Get Book

Basic and Clinical Understanding of Microcirculation by Kaneez Fatima Shad,Nazar Luqman,Seyed Soheil Saeedi Saravi Pdf

Microcirculation is key to providing enough nutrition and oxygen from head to toe. This is possible only through an extensive network of blood vessels spread around the body. Effect of microcirculation abnormalities stretch beyond one’s comprehension. The effects could be felt at any age, from the foetal life to the adulthood. The chapters present in this book describe how these abnormalities could lead to diseases such as atherosclerosis, thrombosis, diabetes, hypertension. Disorders of microcirculation could be related to the structural and/or functional damage to the inner lining of the blood vessels. Early identification of these disorders could benefit many ailments including cardiovascular and cerebrovascular diseases such as heart attack and stroke.

Author : Geert W. Schmid-Schönbein,D.Neil Granger
Publisher : Springer Science & Business Media
Page : 610 pages
File Size : 47,9 Mb
Release : 2013-04-17
Category : Medical
ISBN : 9782817807614

Get Book

Molecular Basis for Microcirculatory Disorders by Geert W. Schmid-Schönbein,D.Neil Granger Pdf

A large number of cardiovascular diseases are accompanied by inflammation. This volume on the molecular basis of microcirculatory disorders gives a comprehensive summary of key steps in the inflammatory cascade. Leading investigators present a state-of-the-art analysis of the molecular determinants of leukocyte-endothelial cell adhesion, mechanotransduction in endothelial and inflammatory cells, mechanisms of cell activation, microvascular apoptosis with applications to ischemia-reperfusion in the brain, the heart and in venous disease, diabetes and hypertension. The book provides the latest thinking in these important cardiovascular problems, with the most contemporary literature and a look at the increasingly complex events during inflammation. Molecular biology tools, microvascular and modern bioengineering analysis are seamlessly integrated into the analysis of clinical problems. The book helps not only newcomers to gain entry into the interesting problems associated with microvascular disorders, but lays the foundation for the design of new therapeutic interventions.

Author : Filippo Crea,Gaetano A. Lanza,Paolo G. Camici
Publisher : Springer Science & Business Media
Page : 257 pages
File Size : 44,6 Mb
Release : 2013-08-15
Category : Medical
ISBN : 9788847053670

Get Book

Coronary Microvascular Dysfunction by Filippo Crea,Gaetano A. Lanza,Paolo G. Camici Pdf

In the past two decades a number of studies have shown that abnormalities in the function and structure of coronary microcirculation can be detected in several cardiovascular diseases. On the basis of the clinical setting in which it occurs, coronary microvascular dysfunction (CMD) can be classified into four types: CMD in the absence of any other cardiac disease; CMD in myocardial diseases; CMD in obstructive epicardial coronary artery disease; and iatrogenic CMD. In some instances CMD represents an epiphenomenon, whereas in others it represents an important marker of risk or may contribute to the pathogenesis of myocardial ischemia, thus becoming a possible therapeutic target. This book provides an update on coronary physiology and a systematic assessment of microvascular abnormalities in cardiovascular diseases, in the hope that it will assist clinicians in prevention, detection and management of CMD in their everyday activity.

Author : Helena Lenasi
Publisher : BoD – Books on Demand
Page : 288 pages
File Size : 41,7 Mb
Release : 2016-10-26
Category : Medical
ISBN : 9789535127307

Get Book

Microcirculation Revisited by Helena Lenasi Pdf

The book provides a comprehensive overview of selected topics in microcirculation, from physiology to pathophysiology including molecular mechanisms and clinical aspects. It contains 10 chapters written by reputed authors, which comprehensively sum up the current knowledge and some interesting new insights in the field of microcirculation. It will be useful to a broad range of audience, from students to highly profiled experts, helping them to expand their knowledge on microcirculation and opening up additional questions for further investigation.

Author : Roland N. Pittman
Publisher : Biota Publishing
Page : 117 pages
File Size : 51,9 Mb
Release : 2016-08-18
Category : Medical
ISBN : 9781615047215

Get Book

Regulation of Tissue Oxygenation, Second Edition by Roland N. Pittman Pdf

This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Author : Paul F. McDonagh
Publisher : S. Karger AG (Switzerland)
Page : 270 pages
File Size : 54,5 Mb
Release : 1987
Category : Biological transport
ISBN : UOM:39015012528264

Get Book

Microvascular Perfusion and Transport in Health and Disease by Paul F. McDonagh Pdf

Author : Javier Escaned,Justin Davies
Publisher : Springer
Page : 313 pages
File Size : 41,7 Mb
Release : 2017-08-10
Category : Medical
ISBN : 9781447152453

Get Book

Physiological Assessment of Coronary Stenoses and the Microcirculation by Javier Escaned,Justin Davies Pdf

​Since the introduction of coronary angiography, a key technique in understanding coronary artery disease, a number of paradigms regarding its study and interpretation have taken place. Following an emphasis on improved angiographic and subsequent intracoronary imaging techniques, functional assessment of coronary circulation has demonstrated to have major implications for diagnosis and treatment of coronary artery disease. Fractional flow reserve, a pressure derived index of stenosis severity, constitutes the best example of the current importance of physiological assessment in clinical practice. However, the acceptance of FFR by cardiologists contrasts with important voids in knowledge on the basic principles of coronary physiology and of other available techniques that, as an alternative to FFR, allow a more comprehensive assessment of coronary circulation. This is particularly noticeable in the assessment of microcirculation, an unavoidable compartment of coronary circulation that is frequently affected in acute coronary syndromes of in the presence of cardiovascular risk factors or non-coronary heart disease. A deeper understanding of the relationship between epicardial vessel and microcirculatory involvement has started with the advent of newer imaging techniques like invasive optical coherence tomography, and non-invasive CT and NMR techniques. This book aims to be an indispensable tool for clinicians and researches in the field of coronary artery disease. It provides a balanced, comprehensive review of anatomy, physiology and available techniques, discusses both the diagnosis of epicardial vessel and microcirculatory disease, the impact of different diseases at different levels of coronary circulation, and the best way to address a separate or combined assessment of different levels of coronary circulation. ​

Author : Giampaolo Niccoli,Ingo Eitel
Publisher : Academic Press
Page : 400 pages
File Size : 46,8 Mb
Release : 2018-07-20
Category : Medical
ISBN : 9780128133613

Get Book

Coronary Microvascular Obstruction in Acute Myocardial Infarction by Giampaolo Niccoli,Ingo Eitel Pdf

Coronary Microvascular Obstruction in Acute Myocardial Infarction: From Mechanisms to Treatment provides a comprehensive understanding of the phenomenon of coronary microvascular obstruction (CMVO) that is the main limitation of reperfusion therapies in ST-elevation myocardial infarction. It provides in-depth coverage of the phenomenon of CMVO which heavily affects prognosis by increasing the risk of death and heart failure at follow-up. A first of its kind reference dedicated solely to this topic, it is appropriate for a wide audience, from researchers, to those who aid in the management, prevention and treatment of CMVO. Provides in-depth coverage of coronary microvascular obstruction (CMVO), spanning research, management, prevention and treatment Includes the most up-to-date information on CMVO as presented from top experts around the word Provides access to a companion website with extra material, including tables, additional references and instructional videos Gives extensive coverage on how to measure CMVO, including in-depth indexes that can be used to detect and quantify the phenomenon

Author : Roe Wells
Publisher : Unknown
Page : 354 pages
File Size : 43,5 Mb
Release : 1973
Category : Medical
ISBN : UOM:39015037513168

Get Book

The Microcirculation in Clinical Medicine by Roe Wells Pdf

Author : Hideyuki Niimi,Masatsugu Hori,Hiroaki Naritomi
Publisher : Unknown
Page : 195 pages
File Size : 49,9 Mb
Release : 1991
Category : Cerebrovascular disease
ISBN : 3718650916

Get Book

Microcirculatory Disorders in the Heart and Brain by Hideyuki Niimi,Masatsugu Hori,Hiroaki Naritomi Pdf

Author : Gabor Kaley,Burton M. Altura
Publisher : Unknown
Page : 560 pages
File Size : 52,9 Mb
Release : 1980
Category : Microcirculation
ISBN : UOM:39015002434002

Get Book

Microcirculation by Gabor Kaley,Burton M. Altura Pdf