Microfluidics And Bio Mems

Author : Francis E. H. Tay
Publisher : Springer Science & Business Media
Page : 346 pages
File Size : 55,6 Mb
Release : 2013-04-17
Category : Technology & Engineering
ISBN : 9781475735345

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Microfluidics and BioMEMS Applications by Francis E. H. Tay Pdf

Microfluidics and BioMEMS Applications central idea is on microfluidics, a relatively new research field which finds its niche in biomedical devices, especially on lab-on-a-chip and related products. Being the essential component in providing driving fluidic flows, an example of micropump is chosen to illustrate a complete cycle in development of microfluidic devices which include literature review, designing and modelling, fabrication and testing. A few articles are included to demonstrate the idea of tackling this research problem, and they cover the main development scope discussed earlier as well as other advanced modelling schemes for microfluidics and beyond. Scientists and students working in the areas of MEMS and microfluidics will benefit from this book, which may serve both communities as both a reference monograph and a textbook for courses in numerical simulation, and design and development of microfluidic devices.

Author : Tuhin S. Santra
Publisher : CRC Press
Page : 0 pages
File Size : 55,7 Mb
Release : 2020-11-01
Category : Medical
ISBN : 9781000769210

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Microfluidics and Bio-MEMS by Tuhin S. Santra Pdf

The past two decades have seen rapid development of micro-/nanotechnologies with the integration of chemical engineering, biomedical engineering, chemistry, and life sciences to form bio-MEMS or lab-on-chip devices that help us perform cellular analysis in a complex micro-/nanoflluidic environment with minimum sample consumption and have potential biomedical applications. To date, few books have been published in this field, and researchers are unable to find specialized content. This book compiles cutting-edge research on cell manipulation, separation, and analysis using microfluidics and bio-MEMS devices. It illustrates the use of micro-robots for biomedical applications, vascularized microfluidic organs-on-a-chip and their applications, as well as DNA gene microarray biochips and their applications. In addition, it elaborates on neuronal cell activity in microfluidic compartments, microvasculature and microarray gene patterning, different physical methods for drug delivery and analysis, micro-/nanoparticle preparation and separation in a micro-/nanofluidic environment, and the potential biomedical applications of micro-/nanoparticles. This book can be used by academic researchers, especially those involved in biomicrofluidics and bio-MEMS, and undergraduate- and graduate-level students of bio-MEMS/bio-nanoelectromechanical systems (bio-NEMS), biomicrofluidics, biomicrofabricatios, micro-/nanofluidics, biophysics, single-cell analysis, bionanotechnology, drug delivery systems, and biomedical micro-/nanodevices. Readers can gain knowledge of different aspects of microfluidics and bio-MEMS devices; their design, fabrication, and integration; and biomedical applications. The book will also help biotechnology-based industries, where research and development is ongoing in cell-based analysis, diagnosis, and drug screening.

Author : Albert Folch
Publisher : CRC Press
Page : 528 pages
File Size : 54,6 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9781466509382

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Introduction to BioMEMS by Albert Folch Pdf

The entire scope of the BioMEMS field-at your fingertipsHelping to educate the new generation of engineers and biologists, Introduction to BioMEMS explains how certain problems in biology and medicine benefit from and often require the miniaturization of devices. The book covers the whole breadth of this dynamic field, including classical microfabr

Author : Koushik Guha,Gorachand Dutta,Arindam Biswas,K. Srinivasa Rao
Publisher : Springer Nature
Page : 251 pages
File Size : 44,8 Mb
Release : 2023-03-13
Category : Technology & Engineering
ISBN : 9789811987144

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MEMS and Microfluidics in Healthcare by Koushik Guha,Gorachand Dutta,Arindam Biswas,K. Srinivasa Rao Pdf

The book introduces the research significance of biomedical instrumentation and discusses micro-fabrication techniques utilized for biomedical devices. This book primarily focuses on the reader enlightenment on MEMS medical devices by introducing all the diagnostic devices and treatment tools at one place. The book covers in-depth technical works and general introductions to the devices such that the book can reach technical as well as non-technical readers.

Author : Wanjun Wang,Steven A. Soper
Publisher : CRC Press
Page : 488 pages
File Size : 52,6 Mb
Release : 2006-12-15
Category : Technology & Engineering
ISBN : 9781420018677

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Bio-MEMS by Wanjun Wang,Steven A. Soper Pdf

Microelectromechanical systems (MEMS) are evolving into highly integrated technologies for a variety of application areas. Add the biological dimension to the mix and a host of new problems and issues arise that require a broad understanding of aspects from basic, materials, and medical sciences in addition to engineering. Collecting the efforts of renowned leaders in each of these fields, BioMEMS: Technologies and Applications presents the first wide-reaching survey of the design and application of MEMS technologies for use in biological and medical areas. This book considers both the unique characteristics of biological samples and the challenges of microscale engineering. Divided into three main sections, it first examines fabrication technologies using non-silicon processes, which use materials that are appropriate for medical/biological analyses. These include UV lithography, LIGA, nanoimprinting, injection molding, and hot-embossing. Attention then shifts to microfluidic components and sensing technologies for sample preparation, delivery, and analysis. The final section outlines various applications and systems at the leading edge of BioMEMS technology in a variety of areas such as genomics, drug delivery, and proteomics. Laying a cross-disciplinary foundation for further development, BioMEMS: Technologies and Applications provides engineers with an understanding of the biological challenges and biological scientists with an understanding of the engineering challenges of this burgeoning technology.

Author : Steven Saliterman
Publisher : SPIE Press
Page : 644 pages
File Size : 43,9 Mb
Release : 2006
Category : Medical
ISBN : 0819459771

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Fundamentals of BioMEMS and Medical Microdevices by Steven Saliterman Pdf

The world is on the threshold of a revolution that will change medicine and how patients are treated forever. Bringing together the creative talents of electrical, mechanical, optical and chemical engineers, materials specialists, clinical-laboratory scientists, and physicians, the science of biomedical microelectromechanical systems (bioMEMS) promises to deliver sensitive, selective, fast, low cost, less invasive, and more robust methods for diagnostics, individualized treatment, and novel drug delivery. This book is an introduction to this multidisciplinary technology and the current state of micromedical devices in use today. The first text of its kind dedicated to bioMEMS training. Fundamentals of BioMEMS and Medical Microdevices is Suitable for a single semester course for senior and graduate-level students, or as an introduction to others interested or already working in the field.

Author : Tuhin S. Santra
Publisher : CRC Press
Page : 548 pages
File Size : 54,9 Mb
Release : 2020-11-01
Category : Medical
ISBN : 9781000769135

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Microfluidics and Bio-MEMS by Tuhin S. Santra Pdf

The past two decades have seen rapid development of micro-/nanotechnologies with the integration of chemical engineering, biomedical engineering, chemistry, and life sciences to form bio-MEMS or lab-on-chip devices that help us perform cellular analysis in a complex micro-/nanoflluidic environment with minimum sample consumption and have potential biomedical applications. To date, few books have been published in this field, and researchers are unable to find specialized content. This book compiles cutting-edge research on cell manipulation, separation, and analysis using microfluidics and bio-MEMS devices. It illustrates the use of micro-robots for biomedical applications, vascularized microfluidic organs-on-a-chip and their applications, as well as DNA gene microarray biochips and their applications. In addition, it elaborates on neuronal cell activity in microfluidic compartments, microvasculature and microarray gene patterning, different physical methods for drug delivery and analysis, micro-/nanoparticle preparation and separation in a micro-/nanofluidic environment, and the potential biomedical applications of micro-/nanoparticles. This book can be used by academic researchers, especially those involved in biomicrofluidics and bio-MEMS, and undergraduate- and graduate-level students of bio-MEMS/bio-nanoelectromechanical systems (bio-NEMS), biomicrofluidics, biomicrofabricatios, micro-/nanofluidics, biophysics, single-cell analysis, bionanotechnology, drug delivery systems, and biomedical micro-/nanodevices. Readers can gain knowledge of different aspects of microfluidics and bio-MEMS devices; their design, fabrication, and integration; and biomedical applications. The book will also help biotechnology-based industries, where research and development is ongoing in cell-based analysis, diagnosis, and drug screening.

Author : Chandra K. Dixit,Ajeet Kaushik
Publisher : Springer
Page : 252 pages
File Size : 47,7 Mb
Release : 2016-10-13
Category : Medical
ISBN : 9783319400365

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Microfluidics for Biologists by Chandra K. Dixit,Ajeet Kaushik Pdf

This book describes novel microtechnologies and integration strategies for developing a new class of assay systems to retrieve desired health information from patients in real-time. The selection and integration of sensor components and operational parameters for developing point-of-care (POC) are also described in detail. The basics that govern the microfluidic regimen and the techniques and methods currently employed for fabricating microfluidic systems and integrating biosensors are thoroughly covered. This book also describes the application of microfluidics in the field of cell and molecular biology, single cell biology, disease diagnostics, as well as the commercially available systems that have been either introduced or have the potential of being used in research and development. This is an ideal book for aiding biologists in understanding the fundamentals and applications of microfluidics. This book also: Describes the preparatory methods for developing 3-dimensional microfluidic structures and their use for Lab-on-a-Chip design Explains the significance of miniaturization and integration of sensing components to develop wearable sensors for point-of-care (POC) Demonstrates the application of microfluidics to life sciences and analytical chemistry, including disease diagnostics and separations Motivates new ideas related to novel platforms, valving technology, miniaturized transduction methods, and device integration to develop next generation sequencing Discusses future prospects and challenges of the field of microfluidics in the areas of life sciences in general and diagnostics in particular

Author : Xiujun (James) Li,Yu Zhou
Publisher : Woodhead Publishing
Page : 724 pages
File Size : 54,7 Mb
Release : 2021-08-05
Category : Technology & Engineering
ISBN : 9780128227558

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Microfluidic Devices for Biomedical Applications by Xiujun (James) Li,Yu Zhou Pdf

Microfluidic Devices for Biomedical Applications, Second Edition provides updated coverage on the fundamentals of microfluidics, while also exploring a wide range of medical applications. Chapters review materials and methods, microfluidic actuation mechanisms, recent research on droplet microfluidics, applications in drug discovery and controlled-delivery, including micro needles, consider applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds, and cover the applications of microfluidic devices in diagnostic sensing, including genetic analysis, low-cost bioassays, viral detection, and radio chemical synthesis. This book is an essential reference for medical device manufacturers, scientists and researchers concerned with microfluidics in the field of biomedical applications and life-science industries. Discusses the fundamentals of microfluidics or lab-on-a-chip (LOC) and explores a wide range of medical applications Considers materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies Details applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and its role in developing tissue scaffolds, and stem cell engineering

Author : Jeffrey T Borenstein,Vishal Tandon,Sarah L Tao,Joseph L. Charest
Publisher : Elsevier
Page : 396 pages
File Size : 53,6 Mb
Release : 2018-09-12
Category : Science
ISBN : 9780128136720

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Microfluidic Cell Culture Systems by Jeffrey T Borenstein,Vishal Tandon,Sarah L Tao,Joseph L. Charest Pdf

Techniques for microfabricating intricate microfluidic structures that mimic the microenvironment of tissues and organs, combined with the development of biomaterials with carefully engineered surface properties, have enabled new paradigms in and cell culture-based models for human diseases. The dimensions of surface features and fluidic channels made accessible by these techniques are well-suited to the size scale of biological cells. Microfluidic Cell Culture Systems applies design and experimental techniques used in in microfluidics, and cell culture technologies to organ-on-chip systems. This book is intended to serve as a professional reference, providing a practical guide to design and fabrication of microfluidic systems and biomaterials for use in cell culture systems and human organ models. The book covers topics ranging from academic first principles of microfluidic design, to clinical translation strategies for cell culture protocols. The goal is to help professionals coming from an engineering background to adapt their expertise for use in cell culture and organ models applications, and likewise to help biologists to design and employ microfluidic technologies in their cell culture systems. This 2nd edition contains new material that strengthens the focus on in vitro models useful for drug discovery and development. One new chapter reviews liver organ models from an industry perspective, while others cover new technologies for scaling these models and for multi-organ systems. Other new chapters highlight the development of organ models and systems for specific applications in disease modeling and drug safety. Previous chapters have been revised to reflect the latest advances. Provides design and operation methodology for microfluidic and microfabricated materials and devices for organ-on-chip disease and safety models. This is a rapidly expanding field that will continue to grow along with advances in cell biology and microfluidics technologies. Comprehensively covers strategies and techniques ranging from academic first principles to industrial scale-up approaches. Readers will gain insight into cell-material interactions, microfluidic flow, and design principles. Offers three fundamental types of information: 1) design principles, 2) operation techniques, and 3) background information/perspectives. The book is carefully designed to strike a balance between these three areas, so it will be of use to a broad range of readers with different technical interests and educational levels.

Author : Simona Badilescu,Muthukumaran Packirisamy
Publisher : CRC Press
Page : 368 pages
File Size : 45,7 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9781439891162

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BioMEMS by Simona Badilescu,Muthukumaran Packirisamy Pdf

Written to cover often overlooked areas in the field of bioMEMS, this volume bridges topics related to biomolecules and complex biological entities with those directly related to the design, fabrication, and characterization of the devices. Unlike other references, this text aids with the fundamental physicochemical understanding of biological processes relevant to the performance of various biosensing devices. Accessible to seniors and graduate students enrolled in engineering programs, the book includes problems in each chapter as well as case studies to provide real-life examples.

Author : Michael R. Hamblin,Mahdi Karimi
Publisher : Academic Press
Page : 352 pages
File Size : 50,5 Mb
Release : 2020-11-12
Category : Technology & Engineering
ISBN : 9780128187920

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Biomedical Applications of Microfluidic Devices by Michael R. Hamblin,Mahdi Karimi Pdf

Biomedical Applications of Microfluidic Devices introduces the subject of microfluidics and covers the basic principles of design and synthesis of actual microchannels. The book then explores how the devices are coupled to signal read-outs and calibrated, including applications of microfluidics in areas such as tissue engineering, organ-on-a-chip devices, pathogen identification, and drug/gene delivery. This book covers high-impact fields (microarrays, organ-on-a-chip, pathogen detection, cancer research, drug delivery systems, gene delivery, and tissue engineering) and shows how microfluidics is playing a key role in these areas, which are big drivers in biomedical engineering research. This book addresses the fundamental concepts and fabrication methods of microfluidic systems for those who want to start working in the area or who want to learn about the latest advances being made. The subjects covered are also an asset to companies working in this field that need to understand the current state-of-the-art. The book is ideal for courses on microfluidics, biosensors, drug targeting, and BioMEMs, and as a reference for PhD students. The book covers the emerging and most promising areas of biomedical applications of microfluidic devices in a single place and offers a vision of the future. Covers basic principles and design of microfluidics devices Explores biomedical applications to areas such as tissue engineering, organ-on-a-chip, pathogen identification, and drug and gene delivery Includes chemical applications in organic and inorganic chemistry Serves as an ideal text for courses on microfluidics, biosensors, drug targeting, and BioMEMs, as well as a reference for PhD students

Author : Society of Photo-optical Instrumentation Engineers,Semiconductor Equipment and Materials International,Solid State Technology (Organization),Sandia National Laboratories
Publisher : SPIE-International Society for Optical Engineering
Page : 410 pages
File Size : 40,9 Mb
Release : 2003
Category : Medical
ISBN : 081944782X

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Microfluidics, BioMEMS, and Medical Microsystems by Society of Photo-optical Instrumentation Engineers,Semiconductor Equipment and Materials International,Solid State Technology (Organization),Sandia National Laboratories Pdf

Author : Samira Hosseini,Michelle Alejandra Espinosa-Hernandez,Ricardo Garcia-Ramirez,Ana Sofia Cerda-Kipper,Sofia Reveles-Huizar,Luis Acosta-Soto
Publisher : Springer Nature
Page : 186 pages
File Size : 40,8 Mb
Release : 2020-08-13
Category : Science
ISBN : 9789811563829

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BioMEMS by Samira Hosseini,Michelle Alejandra Espinosa-Hernandez,Ricardo Garcia-Ramirez,Ana Sofia Cerda-Kipper,Sofia Reveles-Huizar,Luis Acosta-Soto Pdf

This book highlights the latest advances in bioMEMS for biosensing applications. It comprehensively reviews different detection methods, including colorimetric, fluorescence, luminescence, bioluminescence, chemiluminescence, biochemiluminescence, and electrochemiluminescence, and presents various bioMEMS for each, together with recent examples. The book also offers an overview of the history of BioMEMS and the design and manufacture of the first bioMEMS-based devices.

Author : Eric Lagally
Publisher : CRC Press
Page : 290 pages
File Size : 52,8 Mb
Release : 2017-12-19
Category : Medical
ISBN : 9781466594913

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Microfluidics and Nanotechnology by Eric Lagally Pdf

An increasing number of technologies are being used to detect minute quantities of biomolecules and cells. However, it can be difficult to determine which technologies show the most promise for high-sensitivity and low-limit detection in different applications. Microfluidics and Nanotechnology: Biosensing to the Single Molecule Limit details proven approaches for the detection of single cells and even single molecules—approaches employed by the world’s foremost microfluidics and nanotechnology laboratories. While similar books concentrate only on microfluidics or nanotechnology, this book focuses on the combination of soft materials (elastomers and other polymers) with hard materials (semiconductors, metals, and glass) to form integrated detection systems for biological and chemical targets. It explores physical and chemical—as well as contact and noncontact—detection methods, using case studies to demonstrate system capabilities. Presenting a snapshot of the current state of the art, the text: Explains the theory behind different detection techniques, from mechanical resonators for detecting cell density to fiber-optic methods for detecting DNA hybridization, and beyond Examines microfluidic advances, including droplet microfluidics, digital microfluidics for manipulating droplets on the microscale, and more Highlights an array of technologies to allow for a comparison of the fundamental advantages and challenges of each, as well as an appreciation of the power of leveraging scalability and integration to achieve sensitivity at low cost Microfluidics and Nanotechnology: Biosensing to the Single Molecule Limit not only serves as a quick reference for the latest achievements in biochemical detection at the single-cell and single-molecule levels, but also provides researchers with inspiration for further innovation and expansion of the field.