Models For Biomedical Research

Author : P. Michael Conn
Publisher : Springer Science & Business Media
Page : 756 pages
File Size : 49,7 Mb
Release : 2008-03-07
Category : Medical
ISBN : 9781597452854

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Sourcebook of Models for Biomedical Research by P. Michael Conn Pdf

The collection of systems represented in this volume is a unique effort to reflect the diversity and utility of models used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. This volume is therefore a comprehensive and extensive collection of these important medical parallels.

Author : P. Michael Conn
Publisher : Springer Science & Business Media
Page : 756 pages
File Size : 55,5 Mb
Release : 2008
Category : Medical
ISBN : 9781588299338

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Sourcebook of Models for Biomedical Research by P. Michael Conn Pdf

The collection of systems represented in Sourcebook of genomic programs, although this work is certainly well Models for Biomedical Research is an effort to re?ect the represented and indexed. diversity and utility of models that are used in biomedicine. Some models have been omitted due to page limitations That utility is based on the consideration that observations and we have encouraged the authors to use tables and made in particular organisms will provide insight into the ? gures to make comparisons of models so that observations workings of other, more complex, systems. Even the cell not available in primary publications can become useful to cycle in the simple yeast cell has similarities to that in the reader. humans and regulation with similar proteins occurs. We thank Richard Lansing and the staff at Humana for Some models have the advantage that the reproductive, guidance through the publication process. mitotic, development or aging cycles are rapid compared As this book was entering production, we learned of the with those in humans; others are utilized because individual loss of Tom Lanigan, Sr. Tom was a leader and innovator proteins may be studied in an advantageous way and that in scienti?c publishing and a good friend and colleague to have human homologs. Other organisms are facile to grow all in the exploratory enterprise. We dedicate this book to in laboratory settings or lend themselves to convenient analy- his memory. We will miss him greatly.

Author : National Research Council,Commission on Life Sciences,Institute for Laboratory Animal Research,Committee on New and Emerging Models in Biomedical and Behavioral Research
Publisher : National Academies Press
Page : 85 pages
File Size : 54,7 Mb
Release : 1998-02-16
Category : Science
ISBN : 9780309060356

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Biomedical Models and Resources by National Research Council,Commission on Life Sciences,Institute for Laboratory Animal Research,Committee on New and Emerging Models in Biomedical and Behavioral Research Pdf

Printbegrænsninger: Der kan printes 10 sider ad gangen og max. 40 sider pr. session.

Author : William D. Dupont
Publisher : Cambridge University Press
Page : 543 pages
File Size : 46,9 Mb
Release : 2009-02-12
Category : Medical
ISBN : 9780521849524

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Statistical Modeling for Biomedical Researchers by William D. Dupont Pdf

A second edition of the easy-to-use standard text guiding biomedical researchers in the use of advanced statistical methods.

Author : Fabio Bagnoli,Rino Rappuoli
Publisher : Springer Nature
Page : 265 pages
File Size : 46,5 Mb
Release : 2021-05-20
Category : Medical
ISBN : 9783030624521

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Three Dimensional Human Organotypic Models for Biomedical Research by Fabio Bagnoli,Rino Rappuoli Pdf

This edited volume discusses the application of very diverse human organotypic models in major areas of biomedical research. The authors lay a main focus on infectious diseases, cancer, allergies, as well as drug/vaccine discovery and toxicology studies. Representing a valid alternative to laboratory animals, these models are relevant for most areas of translational research. As the contemporary research shows, many human tissues can today be cultivated in vitro and used for several research objectives. This book provides an unprecedented overview of recent developments in an exciting field of research methodology. It is a reference guide for scientists in both academia and industry. Readers can update their knowledge and get hands-on recommendations on how to set up an organotypic model in their lab. Chapters 'Progress on Reconstructed Human Skin Models for Allergy Research and Identifying Contact Sensitizers' and 'Human Organotypic Models for Anti-infective Research' of this book are available open access under a CC BY 4.0 license at link.springer.com.

Author : Anonim
Publisher : National Academies
Page : 196 pages
File Size : 55,5 Mb
Release : 1985-01-01
Category : Technology & Engineering
ISBN : NAP:13080

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Models for Biomedical Research by Anonim Pdf

Author : P. Michael Conn
Publisher : Academic Press
Page : 1108 pages
File Size : 42,8 Mb
Release : 2013-05-29
Category : Science
ISBN : 9780124159129

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Animal Models for the Study of Human Disease by P. Michael Conn Pdf

Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine.The next sections of the work offers models for disease-oriented topics, including cardiac and pulmonary diseases, aging, infectious diseases, obesity, diabetes, neurological diseases, joint diseases, visual disorders, cancer, hypertension, genetic diseases, and diseases of abuse. Organized by disease orientation for ease of searchability Provides information on locating resources, animal alternatives and animal ethics Covers a broad range of animal models used in research for human disease

Author : Yichuan Zhao,Ding-Geng (Din) Chen
Publisher : Springer Nature
Page : 495 pages
File Size : 41,8 Mb
Release : 2020-03-19
Category : Medical
ISBN : 9783030334161

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Statistical Modeling in Biomedical Research by Yichuan Zhao,Ding-Geng (Din) Chen Pdf

This edited collection discusses the emerging topics in statistical modeling for biomedical research. Leading experts in the frontiers of biostatistics and biomedical research discuss the statistical procedures, useful methods, and their novel applications in biostatistics research. Interdisciplinary in scope, the volume as a whole reflects the latest advances in statistical modeling in biomedical research, identifies impactful new directions, and seeks to drive the field forward. It also fosters the interaction of scholars in the arena, offering great opportunities to stimulate further collaborations. This book will appeal to industry data scientists and statisticians, researchers, and graduate students in biostatistics and biomedical science. It covers topics in: Next generation sequence data analysis Deep learning, precision medicine, and their applications Large scale data analysis and its applications Biomedical research and modeling Survival analysis with complex data structure and its applications.

Author : Chow Pierce K H,Ng Robert T H,Ogden Bryan E
Publisher : World Scientific
Page : 308 pages
File Size : 41,9 Mb
Release : 2008-01-02
Category : Technology & Engineering
ISBN : 9789814365413

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Using Animal Models In Biomedical Research: A Primer For The Investigator by Chow Pierce K H,Ng Robert T H,Ogden Bryan E Pdf

Animal models play crucial roles in the continuum of experimental activities that make up biomedical research. Such in vivo modes are especially important in proof-of-principle experiments and in establishing the preclinical safety and efficacy data required for progressing to human clinical trials. A practical understanding of the choice, care and use of animal models is thus expected and required of all biomedical researchers. However, while both legislations and the practice of laboratory animal science have made great advances in the last decade and have impacted significantly on the use of animal models, this corpus of knowledge is not readily available in formats easily digestible to the average biomedical researcher. This book fills this gap in knowledge and provides material not easily sourced by the average biomedical researcher, such as current information on bioimaging, occupational health and biosafety, animal protocol design and histological-pathological support.

Author : C.H. Tyndale-Biscoe,P.A. Janssens
Publisher : Springer Science & Business Media
Page : 253 pages
File Size : 50,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642884023

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The Developing Marsupial by C.H. Tyndale-Biscoe,P.A. Janssens Pdf

Marsupials are excellent objects for studies on developmental processes in all mammals including humans. Marsupials are very immature at birth and undergo most of their development in a pouch where they can be manipulated in a variety of ways without affecting the mother. Most of these studies are on systems which largely mature before birth in eutherian mammals and are consequently difficult to investigate. Attention is also drawn to certain features peculiar to adult marsupials: e.g., they continue to grow throughout adult life, valuable for studies on growth mechanisms, and furthermore the composition of marsupial milk changes radically through lactation, most important in studies of hormonal regulation of milk composition and secretion.

Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Roundtable on Science and Welfare in Laboratory Animal Use
Publisher : National Academies Press
Page : 123 pages
File Size : 51,8 Mb
Release : 2019-08-26
Category : Science
ISBN : 9780309488518

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Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research by National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Roundtable on Science and Welfare in Laboratory Animal Use Pdf

The marmoset, a type of small monkey native to South America, is a research model of increasing importance for biomedical research in the United States and globally. Marmosets offer a range of advantages as animal models in neuroscience, aging, infectious diseases, and other fields of study. They may be particularly useful for the development of new disease models using genetic engineering and assisted reproductive technologies. However, concerns have been voiced with respect to the development of new marmoset-based models of disease, ethical considerations for their use, the supply of marmosets available for research, and gaps in guidance for their care and management. To explore and address these concerns, the Roundtable on Science and Welfare in Laboratory Animal Use hosted a public workshop on October 22-23, 2018, in Washington, DC. The workshop focused on the availability of marmosets in the United States and abroad; animal welfare and ethical considerations stemming from the use of wildtype and genetically modified marmosets; and standards of housing and care, dietary needs, and feeding requirements for marmosets in captivity. This publication summarizes the presentations and discussions from the workshop.

Author : Marschall S. Runge,Cam Patterson
Publisher : Springer Science & Business Media
Page : 604 pages
File Size : 50,7 Mb
Release : 2007-11-14
Category : Medical
ISBN : 9781592598786

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Principles of Molecular Cardiology by Marschall S. Runge,Cam Patterson Pdf

An easy-to-read survey of all the latest developments in molecular cardiologic research and therapy. The authors explain in a readable style the complex process of the heart's development, the molecular basis of cardiovascular diseases, and the translation of these research advances to actual clinical treatments. The expert information provided here serves as an invaluable building block for novel treatments of cardiovascular diseases and includes a comprehensive discussion of cardiac function and dysfunction, coronary artery disease, cardiac arrhythmias, vascular diseases, and risk factors for cardiovascular disease. These state-of-the-art approaches to molecular cardiologic research include critical discussion of such topics as the molecular events that regulate angiogenesis and the potential for angiogenic therapy, emerging therapies for arrhythmias, and a description of the molecular biology of aging and its impact on the cardiovascular system.

Author : Avril D. Woodhead
Publisher : CRC Press
Page : 408 pages
File Size : 46,7 Mb
Release : 1989-11-30
Category : Medical
ISBN : 0849347637

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Nonmammalian Animal Models for Biomedical Research by Avril D. Woodhead Pdf

This book provides essential knowledge and informa-tion required to adequately assess useful alternatives from among the lower vertebrates and the invertebrates. This volume highlights unfamiliar and underde-veloped organisms that have the potential to become very satisfactory surrogates for biomedical research. A practical guide aimed at disseminating information to researchers about new models, this work provides compara-tive biomedical studies at many levels of the phyloge-netic ladder.

Author : National Research Council,Institute of Medicine,Institute for Laboratory Animal Research,Commission on Life Sciences,Committee on the Use of Laboratory Animals in Biomedical and Behavioral Research
Publisher : National Academies Press
Page : 113 pages
File Size : 45,7 Mb
Release : 1988-02-01
Category : Science
ISBN : 9780309038393

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Use of Laboratory Animals in Biomedical and Behavioral Research by National Research Council,Institute of Medicine,Institute for Laboratory Animal Research,Commission on Life Sciences,Committee on the Use of Laboratory Animals in Biomedical and Behavioral Research Pdf

Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.

Author : Anonim
Publisher : Unknown
Page : 380 pages
File Size : 43,9 Mb
Release : 1993
Category : Trademarks
ISBN : PSU:000066191131

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Official Gazette of the United States Patent and Trademark Office by Anonim Pdf