Modern Nucleophilic Aromatic Substitution

Author : Francois Terrier
Publisher : John Wiley & Sons
Page : 488 pages
File Size : 46,8 Mb
Release : 2013-05-20
Category : Science
ISBN : 9783527656165

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Modern Nucleophilic Aromatic Substitution by Francois Terrier Pdf

This book provides a comprehensive overview of nucleophilic aromatic substitutions, focusing on the mechanistic and synthetic features that govern these reactions. The first chapter presents a detailed mechanistic analysis of the factors determining the feasibility of SNAr substitutions, providing decisive information to predict regioselectivity of many reactions and to define the conditions for concerted SNAr processes. Reflecting the key role played by these species as intermediates in most SNAr reactions, chapter 2 then discusses the chemistry of anionic sigma-complexes. Chapter 3 describes the concept of superelectrophilicity in SNAr substitutions, as it has recently emerged from the reactivity of strongly electron-deficient aromatic and heteroaromatic structures. The numerous synthetic applications are considered in depth in the chapters 4 and 5 that follow on intermolecular and intramolecular nucleophilic aromatic substitutions. Then, chapter 6 focuses on substitutions proceeding formally through displacement of a hydride ion, a hot topic in the field. The final chapter brings together concise yet comprehensive discussions surrounding SNAr photosubstitutions, radical substitutions, and ANRORC substitutions. Authored by a highly respected chemist who has contributed greatly to the field over the past two decades, this is a valuable information source for all organic chemists working in academia or the pharmaceutical and agrochemical industries.

Author : Oleg N. Chupakhin,Valery N. Charushin,Henk C. van der Plas
Publisher : Academic Press
Page : 378 pages
File Size : 40,6 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323140591

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Nucleophilic Aromatic Substitution of Hydrogen by Oleg N. Chupakhin,Valery N. Charushin,Henk C. van der Plas Pdf

Nucleophilic aromatic substitution in carbo- and heteroaromatic systems is a subject of considerable interest to chemists. This book uniquely addresses the systematic analysis of a vast range of nucleophilic substitutions of aromatic hydrogen. Nucleophilic displacement of hydrogen (the S N/H reactions) in pi-deficient aromatics, such as nitroarenes, arene-metal complexes, and the like Nucleophilic displacement of hydrogen in heterocyclic substrates such as pyridines, their aza and benzo analogs, pyrylium and thiapyrylium cations, and other heterocycles Mechanisms for the S N/H reactions (S N/H(AE), vicarious nucleophilic substitutions, and radical S N/H substitutions

Author : François Terrier
Publisher : Wiley-VCH
Page : 480 pages
File Size : 41,8 Mb
Release : 1991
Category : Aromatic compounds
ISBN : OSU:32435017504440

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Nucleophilic Aromatic Displacement by François Terrier Pdf

Author : Nicholas J. Turro
Publisher : University Science Books
Page : 644 pages
File Size : 44,7 Mb
Release : 1991
Category : Science
ISBN : 0935702717

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Modern Molecular Photochemistry by Nicholas J. Turro Pdf

During the last two decades the photochemistry of organic molecules has grown into an important and pervasive branch of organic chemistry. In Modern Molecular Photochemistry, the author brings students up to date with the advances in this field - the development of the theory of photoreactions, the utilization of photoreactions in synthetic sequences, and the advancement of powerful laser techniques to study the mechanisms of photoreactions.

Author : Eric V. Anslyn,Dennis A. Dougherty
Publisher : University Science Books
Page : 1148 pages
File Size : 47,8 Mb
Release : 2006
Category : Science
ISBN : 1891389319

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Modern Physical Organic Chemistry by Eric V. Anslyn,Dennis A. Dougherty Pdf

In additionto covering thoroughly the core areas of physical organic chemistry -structure and mechanism - this book will escortthe practitioner of organic chemistry into a field that has been thoroughlyupdated.

Author : Penny Chaloner
Publisher : CRC Press
Page : 1284 pages
File Size : 50,7 Mb
Release : 2014-12-15
Category : Medical
ISBN : 9781482206913

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Organic Chemistry by Penny Chaloner Pdf

Offering a different, more engaging approach to teaching and learning, Organic Chemistry: A Mechanistic Approach classifies organic chemistry according to mechanism rather than by functional group. The book elicits an understanding of the material, by means of problem solving, instead of purely requiring memorization. The text enables a deep unders

Author : Daniel Glossman-Mitnik,Magdalena Maciejewska
Publisher : BoD – Books on Demand
Page : 260 pages
File Size : 54,8 Mb
Release : 2020-01-15
Category : Science
ISBN : 9781789852813

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Solvents, Ionic Liquids and Solvent Effects by Daniel Glossman-Mitnik,Magdalena Maciejewska Pdf

Solvents and ionic liquids are ubiquitous within our whole life since ancient times and their effects are actually being studied through basic sciences like Chemistry, Physics and Biology as well as being researched by a large number of scientific disciplines.This book represents an attempt to present examples on the utility of old and new solvents and the effects they exercise on several fields of academic and industrial interest. The first section, Solvents, presents information on bio-solvents and their synthesis, industrial production and applications, about per and trichloroethylene air monitoring in dry cleaners in the city of Sfax (Tunsia) and on the synthesis of polyimides using molten benzoic acid as the solvent. The second section, Ionic Liquids, shows information about the synthesis, physicochemical characterization and exploration of antimicrobial activities of imidazolium ionic liquid-supported Schiff base and its transition metal complexes, the technology of heterogenization of transition metal catalysts towards the synthetic applications in an ionic liquid matrix, the progress in ionic liquids as reaction media, monomers, and additives in high-performance polymers, a pre-screening of ionic liquids as gas hydrate inhibitor via application of COSMO-RS for methane hydrate, the extraction of aromatic compounds from their mixtures with alkanes from ternary to quaternary (or higher) systems and a review on ionic liquids as environmental benign solvent for cellulose chemistry. The final section, Solvent Effects, displays interesting information on solvent effects on dye sensitizers derived from anthocyanidins for applications in photocatalysis, about the solvent effect on a model of SNAr reaction in conventional and non-conventional solvents, and on solvent effects in supramolecular systems.

Author : Ponnadurai Ramasami
Publisher : Walter de Gruyter GmbH & Co KG
Page : 349 pages
File Size : 40,9 Mb
Release : 2021-06-21
Category : Science
ISBN : 9783110682199

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Computational Chemistry by Ponnadurai Ramasami Pdf

Computational Chemistry serves as a complement to experimental chemistry where the tools are limited. Using computational programs to solve advanced problems is widely used in the design and analysis of for example new molecules, surfaces, drugs and materials. This book will present novel innovations in the field, with real-life examples of where computational technologies serves as an indispensible tool.

Author : Valery Charushin,Oleg Chupakhin
Publisher : Springer
Page : 289 pages
File Size : 55,8 Mb
Release : 2014-09-03
Category : Science
ISBN : 9783319070193

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Metal Free C-H Functionalization of Aromatics by Valery Charushin,Oleg Chupakhin Pdf

The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field.

Author : Michael B. Smith
Publisher : John Wiley & Sons
Page : 2146 pages
File Size : 48,6 Mb
Release : 2020-02-19
Category : Science
ISBN : 9781119371809

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March's Advanced Organic Chemistry by Michael B. Smith Pdf

The completely revised and updated, definitive resource for students and professionals in organic chemistry The revised and updated 8th edition of March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure explains the theories of organic chemistry with examples and reactions. This book is the most comprehensive resource about organic chemistry available. Readers are guided on the planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions The opening chapters of March's Advanced Organic Chemistry, 8th Edition deal with the structure of organic compounds and discuss important organic chemistry bonds, fundamental principles of conformation, and stereochemistry of organic molecules, and reactive intermediates in organic chemistry. Further coverage concerns general principles of mechanism in organic chemistry, including acids and bases, photochemistry, sonochemistry and microwave irradiation. The relationship between structure and reactivity is also covered. The final chapters cover the nature and scope of organic reactions and their mechanisms. This edition: Provides revised examples and citations that reflect advances in areas of organic chemistry published between 2011 and 2017 Includes appendices on the literature of organic chemistry and the classification of reactions according to the compounds prepared Instructs the reader on preparing and conducting multi-step synthetic reactions, and provides complete descriptions of each reaction The 8th edition of March's Advanced Organic Chemistry proves once again that it is a must-have desktop reference and textbook for every student and professional working in organic chemistry or related fields. Winner of the Textbook & Acadmic Authors Association 2021 McGuffey Longevity Award.

Author : Malgorzata Biczysko
Publisher : Frontiers Media SA
Page : 193 pages
File Size : 46,9 Mb
Release : 2021-07-28
Category : Science
ISBN : 9782889711109

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Physical Chemistry and Chemical Physics Editor's Pick 2021 by Malgorzata Biczysko Pdf

Author : Akkattu T. Biju
Publisher : John Wiley & Sons
Page : 530 pages
File Size : 55,5 Mb
Release : 2021-08-23
Category : Science
ISBN : 9783527346462

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Modern Aryne Chemistry by Akkattu T. Biju Pdf

A groundbreaking book to offer a a comprehensive account of important reactions involving arynes Modern Aryne Chemistry is the first book on the market to offer a conceptual framework to the reactions related to arynes. It also provides a systematic introduction to the cycloaddition reactions, insertion reactions and transition-metal-catalyzed transformations of arynes. The author, a noted expert on the topic, highlights a novel strategy for carbon-carbon and carbon-heteroatom bond construction using arynes. The book reveiws the recent use of aryne chemistry for the development of new multicomponent reactions. New advances in this area has shown rapid emergence of a new class of reactions classified under rearrangement reactions. The author also includes information on aryne methods that have been employed for the synthesis of several natural products. The simplicity and sophistication of the synthetic strategy using arynes can serve as a springboard for organic chemists to explore new possibilities and imagine applications of the concept of arynes. This important book: Presents a one-of-kind comprehensive guide to arynes reactions Offers a proven approach to the synthesis of natural product and polymers Reviews the most recent developments in the carbon-carbon and carbon-heteroatom bond-forming reactions involving arynes Written for organic, pharmaceutical, medicinal, natural products, and catalytic Chemists, Modern Aryne Chemistry offers a comprehensive review of the fundamentals of reactions related to arynes and the most recent developments in the field.

Author : Jacques Mortier
Publisher : John Wiley & Sons
Page : 992 pages
File Size : 43,5 Mb
Release : 2015-11-30
Category : Science
ISBN : 9781118754986

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Arene Chemistry by Jacques Mortier Pdf

Organized to enable students and synthetic chemists to understand and expand on aromatic reactions covered in foundation courses, the book offers a thorough and accessible mechanistic explanation of aromatic reactions involving arene compounds. • Surveys methods used for preparing arene compounds and their transformations • Connects reactivity and methodology with mechanism • Helps readers apply aromatic reactions in a practical context by designing syntheses • Provides essential information about techniques used to determine reaction mechanisms

Author : Reza Ranjbar-Karimi ,Alireza Poorfreidoni
Publisher : Bentham Science Publishers
Page : 256 pages
File Size : 45,8 Mb
Release : 2020-09-08
Category : Science
ISBN : 9789811473777

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Perhalopyridines: Synthesis and Synthetic Utility by Reza Ranjbar-Karimi ,Alireza Poorfreidoni Pdf

Halogenated pyridines can be used as interesting starting materials in a wide range of organic synthesis methods. Substituted pyridine compounds are used generally as starting materials in the nucleophilic substitution reactions and have unique scaffolds for the construction of other heterocyclic and macrocyclic compounds. They also have important medicinal properties. Due to synthetic difficulties in the synthesis of the highly substituted pyridine derivatives from pyridine itself, perhalopyridines have a special importance in this regard. This book covers the synthetic reactions and applications of perhalopyridines. An introductory chapter introduces the reader to the physical and chemical properties of halopyridines, followed by 3 chapters which focus on pentafluoropyridine, pentachloropyridine and pentabromopyridine, respectively. The focused chapters provide information about synthetic methods and relevant nucleophilic reactions for each of the listed perhalopyridines and their derivatives. The book is a quick reference on perhalopyridines for students of applied chemistry, organic chemistry and chemical engineering.

Author : Atta-ur-Rahman,Kenneth K. Laali
Publisher : Bentham Science Publishers
Page : 594 pages
File Size : 52,7 Mb
Release : 2011-01-10
Category : Science
ISBN : 9781608051984

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Advances in Organic Synthesis by Atta-ur-Rahman,Kenneth K. Laali Pdf

"The volume focuses on recent advances in organofluorine chemistry directed towards selective fluorine introduction into various target molecules, employing both traditional and contemporary, electrophilic and nucleophilic, fluorinating agents. It brings t"