Modern Visualisation Of The Endothelium

Author : J M Polak
Publisher : CRC Press
Page : 264 pages
File Size : 51,7 Mb
Release : 1998-07-16
Category : Science
ISBN : 905702294X

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Modern Visualisation of the Endothelium by J M Polak Pdf

There can no longer be any doubt that the endothelium represents a very active tissue and is not, as had previously been thought, merely an inert lining material. On the contrary, the endothelium exerts a powerful influence on its environs through the release of multiple regulatory factors such as nitric oxide, endothelium derived hyperpolarizing factor and endothelin. It is therefore crucial to our understanding of the cardiovascular system that we are able to visualize the endothelial layer at the molecular level. Quantitative morphological studies permit visualization at this level, allowing the assessment of the changes that occur in the disease state. Modern methods of computerized image analysis have been applied to reconstruct the endothelial layer in three-dimensions - detecting even the most subtle of changes. Within these covers, an integrated text has been gathered by experts in each of their fields. They detail the latest technical and conceptual advances in the visualization of endothelium, its production of regulatory molecules and pathological changes.

Author : Werner Risau,Gabor M. Rubanyi
Publisher : CRC Press
Page : 312 pages
File Size : 55,6 Mb
Release : 2003-09-02
Category : Science
ISBN : 9780203304358

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Morphogenesis of Endothelium by Werner Risau,Gabor M. Rubanyi Pdf

The cardiovascular system is the first functional organ system to develop in the vertebrate embryo. Embryonic growth and differentiation essentially depend on transport of nutrients and waste through the early vasculature, and certain events in morphogenesis are thought to be influenced by the hemodynamic forces of the beating heart. The vasculature not only serves as a 'nutrient and waste pipeline' but is also a major communication system between distant organs and tissues. The vascular endothelial cell mediates vascular growth, permeability, integrity and interactions with blood cells. In most tissues the endothelium itself is highly specialized to meet the particular needs of the tissue in terms of quality and quantity of incoming and outgoing molecules and messages. The areas covered by Morphogenesis of the Endothelium include the formation of blood vessels in embryonic tissues by vasculogenesis and angiogenesis and the differentiation of endothelium in organs. The contributors are leaders in the field of cardiovascular development, biology and pathology and have written up to date chapters on the mechanisms of blood vessel formation and function in embryos and the adult.

Author : Patrick J Vallance,David J. Webb
Publisher : CRC Press
Page : 302 pages
File Size : 55,9 Mb
Release : 2003-09-02
Category : Medical
ISBN : 9781482283563

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Vascular Endothelium in Human Physiology and Pathophysiology by Patrick J Vallance,David J. Webb Pdf

Endothelial dysfunction is now regarded as an early marker of vascular disease and therefore an important target for therapeutic intervention and discovery of novel treatments. Ideal for both basic and clinical scientists, whether in industry or academia, and physicians, Vascular Endothelium in Human Physiology and Pathophysiology provides an up-to

Author : Michael A Gimbrone
Publisher : CRC Press
Page : 388 pages
File Size : 40,5 Mb
Release : 1999-08-19
Category : Medical
ISBN : 9780203303849

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Mechanical Forces and the Endothelium by Michael A Gimbrone Pdf

Areas addressed in this excellent text include the overall response of the endothelium to hemodynamic forces, and molecular biology with gene regulation taking a central role.

Author : Paul M. Vanhoutte
Publisher : CRC Press
Page : 364 pages
File Size : 41,8 Mb
Release : 1996-12-13
Category : Science
ISBN : 3718659298

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Endothelium-Derived Hyperpolarizing Factor by Paul M. Vanhoutte Pdf

Author : Malcolm J Lewis,Ajay M Shah
Publisher : CRC Press
Page : 272 pages
File Size : 42,5 Mb
Release : 2020-01-29
Category : Medical
ISBN : 9781000725346

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Endothelial Modulation of Cardiac Function by Malcolm J Lewis,Ajay M Shah Pdf

Paracrine and autocrine regulation of cardiac function by "endothelial" mediators is becoming important both physiologically and pathophysiologically. This volume brings the researcher completely up to date with all aspects of endothelial regulation and cardiac function. Acknowledged experts in each field have contributed, making this work indispensable for researchers and of great interest to the clinical cardiologist. The Endothelial Cell Research Series publishes significant reviews by experts in the field. The individual volumes provide invaluable guides to researchers studying endothelial cells and are effective reference texts for anyone working in the general areas of vascular biology and neurotransmission. Endothelium was originally considered to be an inert lining for the blood vessels, but during the last fifteen years, this view has had to be completely revised. It is now accepted that the endothelium plays an important role in many diverse functions. This volume concentrates on the effect of the endothelium on cardiac function. It has been widely demonstrated that the endothelium exerts a paracrine influence on contraction of adjacent cardiac muscle through the release of several mediators, such as endothelin and nitric oxide. Recent studies also show that the effects of such mediators upon the heart are not limited to contraction alone.

Author : Gabor M. Rubanyi
Publisher : CRC Press
Page : 378 pages
File Size : 41,5 Mb
Release : 2003-09-02
Category : Science
ISBN : 9780203303726

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Pathophysiology and Clinical Applications of Nitric Oxide by Gabor M. Rubanyi Pdf

Research on the key mediator nitric oxide has increased exponentially over the last ten years. It is now clear that, in addition to its role within the cardiovascular system, this mediator is also implicated in the normal physiological function and disease pathology of several organs and systems. A number of the fundamental research observations are now being developed into therapeutic principles and these are being pursued through clinical trials. This is the first work summarizing, in its two volumes, the quantum leap from basic science to clinical applications emerging from this decade of research.

Author : Gabor M. Rubanyi,Victor J. Dzau,John P. Cooke
Publisher : CRC Press
Page : 492 pages
File Size : 43,6 Mb
Release : 2002-02-21
Category : Medical
ISBN : 0203166477

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Vascular Protection by Gabor M. Rubanyi,Victor J. Dzau,John P. Cooke Pdf

Vascular Protection explores advances in vascular biology and how they translate into innovations in drug therapy for vascular disease. It addresses recent advances in the knowledge of endothelial vasoactive factors and other biologically active molecules as well as gene therapy. Written by leading experts in their respective fields, each chapter e

Author : Gabor M. Rubanyi,R Kauffman
Publisher : CRC Press
Page : 279 pages
File Size : 42,8 Mb
Release : 2003-09-02
Category : Science
ISBN : 9780203303931

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Estrogen and the Vessel Wall by Gabor M. Rubanyi,R Kauffman Pdf

Estrogen and the Vessel Wall marks the start of a new era in understanding the cardiovascular actions of estrogen. It examines the hypothesis, derived from a growing body of epidemiological data, that estrogen acts directly upon the vessel wall to produce beneficial effects in the cardiovascular system. Inspired by a satellite symposium of the IX International Vascular Biology Meeting, additional topics have been included, covered by leading experts. All subjects have been brought together here to produce an outstanding and integral publication, a milestone in the field of Vascular Research.

Author : John D. Catravas,Allan D. Callow,Una S. Ryan
Publisher : IOS Press
Page : 312 pages
File Size : 52,6 Mb
Release : 1999
Category : Science
ISBN : 9051994435

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Vascular Endothelium by John D. Catravas,Allan D. Callow,Una S. Ryan Pdf

With its innovative topical approach, bestselling COMPARATIVE CRIMINAL JUSTICE SYSTEMS, 5e offers a comprehensive analysis as it compares the various criminal justice systems throughout the world using six model countries: China, England, France, Germany, Japan, and Saudi Arabia. The text illustrates the different types of law and justice systems while exploring the historical, political, economic, social, and cultural influences on each system. This unique approach examines important aspects of each type of justice system--common law, civil law, socialist law, and sacred (Islamic) law--to give students a thorough understanding of the similarities and differences of each system without overloading them with too much information. Completely up to date, the Fifth Edition includes the latest trends and issues in international juvenile justice, policing, and terrorism, including expanded coverage of such high- profile topics as human trafficking, Internet pornography, identity theft, transnational policing, and more.

Author : Jorge L. Alió,Jorge L. Alió del Barrio
Publisher : Springer Nature
Page : 521 pages
File Size : 52,8 Mb
Release : 2023-10-27
Category : Medical
ISBN : 9783031324086

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Modern Keratoplasty by Jorge L. Alió,Jorge L. Alió del Barrio Pdf

​Keratoplasty techniques have evolved in the last 15 years into a variety of forms, which have diversified the previous monographic presence of the penetrating keratoplasty technique. The development of anterior lamellar graft (DALK), and posterior lamellar graft (DSAEK), makes an important change in the approach to lamellar surgery. Later on, the appearance of DMEK and superficial lamellar keratectomy broadened the spectrum. Today, intralamellar surgery has evolved with a number of techniques that involve stromal enhancement with biologically active or acellular corneal laminas from donors, customized lenticles from SMILE surgeries or customized by corneal topography, and more recently, corneal regeneration of the stroma by advanced techniques using mesenchymal stem cells. This book offers a comprehensive overview of modern keratoplasty techniques, the technology, surgical skills, and outcomes. It highlights the practical uses of keratoplasty for all cornea surgeons and anterior segment surgeons. The book is divided into sections, each covering a specific type of keratoplasty, including chapters on innovations within each surgery type. The goal of this book is to unify all recent knowledge about the different keratoplasty techniques and outcomes, creating a one-stop resource for ophthalmaolgy surgeons. Modern Keratoplasty is a must-have resource for corneal specialists and surgeons, anterior segment surgeons, refractive surgeons, cataract surgeons, residents, fellows, and corneal researchers.

Author : Elizabeth Sleeman
Publisher : Psychology Press
Page : 728 pages
File Size : 46,8 Mb
Release : 2001
Category : Biography & Autobiography
ISBN : 1857431227

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The International Who's Who of Women 2002 by Elizabeth Sleeman Pdf

Over 5,500 detailed biographies of the most eminent, talented and distinguished women in the world today.

Author : Shashank K. Singh
Publisher : Bentham Science Publishers
Page : 352 pages
File Size : 44,9 Mb
Release : 2021-11-17
Category : Medical
ISBN : 9789814998673

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Modern Cancer Therapies and Traditional Medicine: An Integrative Approach to Combat Cancers by Shashank K. Singh Pdf

The advancements in molecular marker discovery, genomics, transcriptomics and proteomics in recent years have enabled researchers to develop targeted therapies against cancers. Cancer research and management is multi-disciplinary and multimodal. In addition to conventional chemotherapy and radiotherapy, targeted immunotherapy has also provided considerable success in the clinic. There is also scientific evidence on the impact of alternative therapies on cancer patients. Modern Cancer Therapies and Traditional Medicine: An Integrative Approach to Combat Cancers summarizes the general aspects of cancer therapy and management. Chapters cover cancer medicine in two broad sections, the book presents comprehensive information on a diverse range of cancer treatments. The first section covers conventional molecular oncology and therapy including targeted therapies, immunotherapies, cancer signaling pathways and the use of computational techniques. The second section focuses on traditional methods of treatment including the role of nutrition, traditional medicine, Yoga and Ayurveda in cancer prevention and management. The book is an accessible update of the state of the art in cancer diagnostics and therapy for students and academicians at all levels.

Author : Thomas John
Publisher : Boydell & Brewer Ltd
Page : 464 pages
File Size : 49,7 Mb
Release : 2010-09-17
Category : Medical
ISBN : 8184487924

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Corneal Endothelial Transplant DSEAK, DMEK and DLEK by Thomas John Pdf

A timely, outstanding educational resource dedicated to explaining the new method of performing corneal transplantation without the use of corneal sutures and an absence of full-thickness corneal wound. This comprehensive book includes a discussion of the development of lamellar transplantation; an in-depth discussion of the basic science of corneal structure, physiology, biomechanics and pathology; a primer on advanced corneal imaging; and a review of the surgical techniques and instrumentation required.

Author : Norbert Voelkel,Sharon Rounds
Publisher : John Wiley & Sons
Page : 547 pages
File Size : 51,6 Mb
Release : 2009-11-16
Category : Medical
ISBN : 9780470723616

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The Pulmonary Endothelium by Norbert Voelkel,Sharon Rounds Pdf

The Pulmonary Endothelium is a uniquely comprehensive compendium of our current knowledge of the pulmonary endothelium and is the first book dedicated specifically to the subject, offering insights into current and future approaches to management. The text provides the clinician with the most up-to-date information on one of the core physiological processes in airway disease and is an ideal point of reference for both postgraduates and professionals – specialist physicians in pulmonology and allergy and workers in biomedical and pharmaceutical research.