Molecular Biology And Evolution Of Blood Group And Mhc Antigens In Primates

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Molecular Biology and Evolution of Blood Group and MHC Antigens in Primates

Antoine Blancher,Jan Klein,Wladyslaw W. Socha
Molecular Biology and Evolution of Blood Group and MHC Antigens in Primates Book PDF

Author : Antoine Blancher,Jan Klein,Wladyslaw W. Socha
Publisher : Springer Science & Business Media
Page : 578 pages
File Size : 54,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642590863

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Molecular Biology and Evolution of Blood Group and MHC Antigens in Primates by Antoine Blancher,Jan Klein,Wladyslaw W. Socha Pdf

Zoologists have categorized primates into a single order, and no one doubts today that they share a common ancestry. Humans and Old and New World non human primate species, from the lemurs of Madagascar to the African anthro poid apes, represent diverging branches of an evolutionary common trunk. Along with species-specific characters, all primates have retained a number of ancestral traits, relics of their common origin. The comparative study of these species-specific and ancestral traits makes it possible to reconstruct the evolu tionary pathways of humans and nonhuman primates. The discovery of the human blood groups and, later, of the Major Histocom patibility Complex (MHC) had a seminal effect on the field of human genetics, providing the first sound examples of mendel ian polymorphisms. The use of blood group and MHC alleles as genetic markers in biological anthropology gen erated a conceptual revolution and persuaded researchers to begin to think in terms of populations and not only intems of typology. The counterparts of these human red and white cell antigens were found and studied in nunhuman primates, and progress in this field is summarized in this book.

Human Blood Groups

Geoff Daniels
Human Blood Groups Book PDF

Author : Geoff Daniels
Publisher : John Wiley & Sons
Page : 950 pages
File Size : 51,9 Mb
Release : 2013-01-16
Category : Medical
ISBN : 9781118493540

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Human Blood Groups by Geoff Daniels Pdf

Human Blood Groups is a comprehensive and fully referenced text covering both the scientific and clinical aspects of red cell surface antigens, including: serology, inheritance, biochemistry, molecular genetics, biological functions and clinical significance in transfusion medicine. Since the last edition, seven new blood group systems and over 60 new blood group antigens have been identified. All of the genes representing those systems have now been cloned and sequenced. This essential new information has made the launch of a third edition of Human Blood Groups, now in four colour, particularly timely. This book continues to be an essential reference source for all those who require clinical information on blood groups and antibodies in transfusion medicine and blood banking.

Blood Banking and Transfusion Medicine E-Book

Christopher D. Hillyer,Leslie E. Silberstein,Paul M. Ness,Kenneth C. Anderson,John D. Roback
Blood Banking and Transfusion Medicine E Book Book PDF

Author : Christopher D. Hillyer,Leslie E. Silberstein,Paul M. Ness,Kenneth C. Anderson,John D. Roback
Publisher : Elsevier Health Sciences
Page : 912 pages
File Size : 52,9 Mb
Release : 2006-11-21
Category : Medical
ISBN : 9780702036255

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Blood Banking and Transfusion Medicine E-Book by Christopher D. Hillyer,Leslie E. Silberstein,Paul M. Ness,Kenneth C. Anderson,John D. Roback Pdf

Ever since the discovery of blood types early in the last century, transfusion medicine has evolved at a breakneck pace. This second edition of Blood Banking and Transfusion Medicine is exactly what you need to keep up. It combines scientific foundations with today's most practical approaches to the specialty. From blood collection and storage to testing and transfusing blood components, and finally cellular engineering, you'll find coverage here that's second to none. New advances in molecular genetics and the scientific mechanisms underlying the field are also covered, with an emphasis on the clinical implications for treatment. Whether you're new to the field or an old pro, this book belongs in your reference library. Integrates scientific foundations with clinical relevance to more clearly explain the science and its application to clinical practice. Highlights advances in the use of blood products and new methods of disease treatment while providing the most up-to-date information on these fast-moving topics Discusses current clinical controversies, providing an arena for the discussion of sensitive topics. Covers the constantly changing approaches to stem cell transplantation and brings you the latest information on this controversial topic.

Basics in Human Evolution

Michael P Muehlenbein
Basics in Human Evolution Book PDF

Author : Michael P Muehlenbein
Publisher : Academic Press
Page : 584 pages
File Size : 40,8 Mb
Release : 2015-07-24
Category : Science
ISBN : 9780128026939

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Basics in Human Evolution by Michael P Muehlenbein Pdf

Basics in Human Evolution offers a broad view of evolutionary biology and medicine. The book is written for a non-expert audience, providing accessible and convenient content that will appeal to numerous readers across the interdisciplinary field. From evolutionary theory, to cultural evolution, this book fills gaps in the readers’ knowledge from various backgrounds and introduces them to thought leaders in human evolution research. Offers comprehensive coverage of the wide ranging field of human evolution Written for a non-expert audience, providing accessible and convenient content that will appeal to numerous readers across the interdisciplinary field Provides expertise from leading minds in the field Allows the reader the ability to gain exposure to various topics in one publication

Human Gene Evolution

David Neil Cooper
Human Gene Evolution Book PDF

Author : David Neil Cooper
Publisher : Elsevier
Page : 520 pages
File Size : 54,8 Mb
Release : 1999-11-03
Category : Science
ISBN : 0121878708

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Human Gene Evolution by David Neil Cooper Pdf

Presents the principles of human gene evolution in a concise and easy to understand fashion. Uses examples of how evolutionary processes have molded present day genes, drawn from the evolution of humans and other primates, as well as from more primitive organisms. With increasing attention in this expanding area, this review forms a timely publication of our current knowledge of this important field. Structure and function in the human genome The evolution of gene structure Mutational mechanisms in evolution

Major Histocompatibility Complex

M. Kasahara
Major Histocompatibility Complex Book PDF

Author : M. Kasahara
Publisher : Springer Science & Business Media
Page : 574 pages
File Size : 55,5 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9784431658689

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Major Histocompatibility Complex by M. Kasahara Pdf

Every biological system is the outcome of evolution and has a history all its own. This history dictates how the system works and why it has certain properties and not others. This is why we need to study not only the structure and function, but also the history of the system. This argument undoubtedly applies to the study of the immune system and also to the study of the major histocompatibility complex (MHC). Since 1989, researchers of various scientific disciplines who share a deep inter est in MHC evolution have held a meeting every two years to discuss their latest research developments, exchange ideas, and foster friendship. Together with my colleagues Drs. Naoyuki Takahata and Yoko Satta, I organized the Sixth Interna tional Workshop on MHC Evolution in Hayama, Japan, May 25-29, 1999. This volume is the proceedings of that conference. It covers diverse topics pertinent to MHC evolution, including the origin of the adaptive immune system, the organi zation of the MHC in humans and other model vertebrates, MHC-parasite co evolution, and the nature and origin of MHC polymorphism. I hope that this book will be of interest not only for MHC researchers and immunologists, but also for other specialists who are interested in the evolution of biological systems in gen eral.

Human Blood Cells: Consequences Of Genetic Polymorphisms And Variations

May-jean King
Human Blood Cells Consequences Of Genetic Polymorphisms And Variations Book PDF

Author : May-jean King
Publisher : World Scientific
Page : 420 pages
File Size : 53,7 Mb
Release : 2000-07-04
Category : Medical
ISBN : 9781911298939

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Human Blood Cells: Consequences Of Genetic Polymorphisms And Variations by May-jean King Pdf

This important book uses selected molecules expressed on erythrocytes, lymphocytes, platelets and granulocytes to illustrate how genetic polymorphisms and variations in these molecules can affect their structure and function in mature human blood cells. The examples described tend to have a clinical association. Human blood group antigens and HLA antigens are classic examples of genetic polymorphism and they are important in blood transfusion and organ transplantation, respectively. In common with the blood group antigens, the polymorphic and variant antigens on platelets and granulocytes can be targets for antibodies in feto-maternal antigen incompatibility and transfusion reactions. Certain inherited haemolytic anaemias can be attributed to some of the polymorphic and variant forms of erythrocyte anion transport protein, spectrin, and glucose-6-phosphate dehydrogenase which exhibit abnormal structural or functional properties. Similarly, the study of cytokine gene polymorphism can provide a further understanding of the immune/inflammatory diseases and allogeneic transplantation./a

Blood and Bone Marrow Pathology E-Book

Anna Porwit,Jeffrey McCullough,Wendy N Erber
Blood and Bone Marrow Pathology E Book Book PDF

Author : Anna Porwit,Jeffrey McCullough,Wendy N Erber
Publisher : Elsevier Health Sciences
Page : 724 pages
File Size : 45,6 Mb
Release : 2011-05-27
Category : Medical
ISBN : 9780702045356

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Blood and Bone Marrow Pathology E-Book by Anna Porwit,Jeffrey McCullough,Wendy N Erber Pdf

Chapters have been totally rewritten and some new chapters have been added especially on myeloid malignancies, in line with the WHO 2008 Classification All chapters have been revised to include new aspects of molecular biology and updated concerning flow cytometry diagnostics Greater emphasis on practical diagnostic aspects for all disorders Brand new editorial and contributing author team. Full Online text through Expert Consult. Full downloadable Image Bank

The Primate Fossil Record

Walter Carl Hartwig
The Primate Fossil Record Book PDF

Author : Walter Carl Hartwig
Publisher : Cambridge University Press
Page : 554 pages
File Size : 51,9 Mb
Release : 2002-04-11
Category : Science
ISBN : 0521663156

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The Primate Fossil Record by Walter Carl Hartwig Pdf

A comprehensive treatment of primate paleontology. Profusely illustrated and up to date, it captures the complete history of the discovery and interpretation of primate fossils. The chapters range from primate origins to the advent of anatomically modern humans. Each emphasizes three key components of the record of primate evolution: history of discovery, taxonomy of the fossils, and evolution of the adaptive radiations they represent. The Primate Fossil Record summarizes objectively the many intellectual debates surrounding the fossil record and provides a foundation of reference information on the last two decades of astounding discoveries and worldwide field research for physical anthropologists, paleontologists and evolutionary biologists.

Protecting Infants through Human Milk

Larry K. Pickering,Ardythe L. Morrow,Guillermo M. Ruiz-Palacios,Richard J. Schanler
Protecting Infants through Human Milk Book PDF

Author : Larry K. Pickering,Ardythe L. Morrow,Guillermo M. Ruiz-Palacios,Richard J. Schanler
Publisher : Springer Science & Business Media
Page : 506 pages
File Size : 49,8 Mb
Release : 2013-06-29
Category : Medical
ISBN : 9781475742428

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Protecting Infants through Human Milk by Larry K. Pickering,Ardythe L. Morrow,Guillermo M. Ruiz-Palacios,Richard J. Schanler Pdf

Protecting Infants through Human Milk: Advancing the Scientific Evidence provides a forum in which basic scientists, clinicians, epidemiologists, and policy makers exchange the latest findings regarding the effects of human milk and breastfeeding on infant and maternal health, thereby fostering new and promising collaborations. This volume also integrates data from animal and in vitro laboratory studies with clinical and population studies to examine human milk production and composition, the mechanisms of infant protection and/or risk from human milk feeding, and proposed interventions related to infant feeding practices. Additionally, it stimulates critical evaluation of, and advances in, the scientific evidence base and research methods, and identifies the research priorities in various areas.

Proceedings of the Zoo and Wildlife Health Conference 2023

Rafaela Fiuza,Gidona Goodman,Ana Vale,Linda Bruins-Van Sonsbeek
Proceedings of the Zoo and Wildlife Health Conference 2023 Book PDF

Author : Rafaela Fiuza,Gidona Goodman,Ana Vale,Linda Bruins-Van Sonsbeek
Publisher : BoD – Books on Demand
Page : 172 pages
File Size : 43,9 Mb
Release : 2023-05-10
Category : Medical
ISBN : 9783744890274

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Proceedings of the Zoo and Wildlife Health Conference 2023 by Rafaela Fiuza,Gidona Goodman,Ana Vale,Linda Bruins-Van Sonsbeek Pdf

These are the proceedings of the Zoo and Wildlife Health Conference organised by the European Association of Zoo and Wildlife Veterinarians, held at Universidad Cardenal Herrera , Valencia, Spain. and hosted by Bioparc Valencia, Spain from 7-10 June 2023

α–Gal and Anti–Gal

Uri Galili,José-Luis Avila
Gal and Anti Gal Book PDF

Author : Uri Galili,José-Luis Avila
Publisher : Springer Science & Business Media
Page : 404 pages
File Size : 49,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461547716

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α–Gal and Anti–Gal by Uri Galili,José-Luis Avila Pdf

Uri Galili who originally discovered anti-Gal and the unique evolution of &agr;-1,3-galactosyltransferase, and by Dr. Jose-Luis Avila who has been studying anti-Gal significance in Chagas' disease and in Leishmania infections. This book covers the main areas of research on &agr;-1,3galactosyltransferase, its product the &agr;-gal epitope (Gal&agr;1-3Gal&bgr;1-4GlcNAc-R) and the natural anti-Gal antibody that interacts with this epitope

Major Histocompatibility Complex (MHC) in Health and Disease

Jerzy K. Kulski,Takashi Shiina,Johannes M. Dijkstra
Major Histocompatibility Complex MHC in Health and Disease Book PDF

Author : Jerzy K. Kulski,Takashi Shiina,Johannes M. Dijkstra
Publisher : MDPI
Page : 374 pages
File Size : 51,6 Mb
Release : 2020-01-15
Category : Science
ISBN : 9783039280728

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Major Histocompatibility Complex (MHC) in Health and Disease by Jerzy K. Kulski,Takashi Shiina,Johannes M. Dijkstra Pdf

The major histocompatibility complex (MHC) is a highly polymorphic and diverse multigene locus in all jawed vertebrate species that has an integral role in adaptive/innate immune systems, transplantation, and infectious and autoimmune diseases. The MHC supra-locus in mammalian vertebrates is usually partitioned into three distinct regions, known as classes I, II, and III, which, to varying extents, can be found conserved in nonmammalian jawed vertebrates, such as bony fish, amphibians, and bird lineages. The MHC gene region is characterized particularly by the expression of class I and class II glycoproteins that bind peptides derived from intracellular or extracellular antigens to circulating T-cells. While this expressed antigenic specificity remains the predominant interest with respect to MHC function and polymorphism in a population, a broader concept has emerged that examines the MHC as a multifunctional polymorphic controller that facilitates and regulates genome diversity with a much greater array of functions and effects than just MHC-restricted antigen recognition. This volume of 19 reprints presented by various experts and collected from the Special Issue of Cells on “MHC in Health and Disease” covers a broad range of topics on the genomic diversity of the MHC regulatory system in various vertebrate species, including MHC class I, II, and III genes; innate and adaptive immunity; neurology; transplantation; haplotypes; infectious and autoimmune diseases; fecundity; conservation; allelic lineages; and evolution. Taken together, these articles demonstrate the immense complexity and diversity of the MHC structure and function within and between different vertebrate species.

Evolution of the Human Genome I

Naruya Saitou
Evolution of the Human Genome I Book PDF

Author : Naruya Saitou
Publisher : Springer
Page : 305 pages
File Size : 50,6 Mb
Release : 2018-02-08
Category : Science
ISBN : 9784431566038

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Evolution of the Human Genome I by Naruya Saitou Pdf

This book reviews the human genome from an evolutionary perspective. No such book has ever been published before, although there are many books on human genomes. There are two parts in this book: Overview of the Human Genome (Part I) and The Human Genome Viewed through Genes (Part II). In Part I, after a brief review of human evolution and the human genome (by Naruya Saitou), chapters on rubbish or junk DNA (by Dan Graur), GC content heterogeneity (by Satoshi Oota), protein coding and RNA coding genes (by Tadashi Imanishi), duplicated genes (by Takashi Kitano), recombinations (by Montanucci and Bertranpetit), and copy number variations including microsatellites (by Naoko Takezaki) are discussed. Readers can obtain various new insights on the human genome from this part. In Part II, genes in X and Y chromosomes (by Yoko Satta and others), HLA genes (by Timothy A. Jinam), opsin genes (by Shoji Kawamura and Amanda D. Melin), genes related to phenotypic variations (by Ryosuke Kimura), transcription factors (by Mahoko Takahashi and So Nakagawa), diabetes-related genes (by Ituro Inoue), disease genes in general (by Ituro Inoue and Hirofumi Nakaoka), and microbial genomes (by Chaochun Wei) are discussed. The human genome sequences were determined in 2004, and after more than 10 years we are now beginning to understand the human genome from an evolutionary point of view. This book furnishes readers with a good summary of current research in the field.

Chimpanzees in Biomedical and Behavioral Research

National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Institute of Medicine,Board on Health Sciences Policy,Committee on the Use of Chimpanzees in Biomedical and Behavioral Research
Chimpanzees in Biomedical and Behavioral Research Book PDF

Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Institute of Medicine,Board on Health Sciences Policy,Committee on the Use of Chimpanzees in Biomedical and Behavioral Research
Publisher : National Academies Press
Page : 200 pages
File Size : 54,5 Mb
Release : 2012-01-05
Category : Science
ISBN : 9780309220392

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Chimpanzees in Biomedical and Behavioral Research by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Institute of Medicine,Board on Health Sciences Policy,Committee on the Use of Chimpanzees in Biomedical and Behavioral Research Pdf

For many years, experiments using chimpanzees have been instrumental in advancing scientific knowledge and have led to new medicines to prevent life-threatening and debilitating diseases. However, recent advances in alternate research tools have rendered chimpanzees largely unnecessary as research subjects. The Institute of Medicine, in collaboration with the National Research Council, conducted an in-depth analysis of the scientific necessity for chimpanzees in NIH-funded biomedical and behavioral research. The committee concludes that while the chimpanzee has been a valuable animal model in the past, most current biomedical research use of chimpanzees is not necessary, though noted that it is impossible to predict whether research on emerging or new diseases may necessitate chimpanzees in the future.