Molecular Biology Of Bacterial Infection

Author : Carlos E. Hormaeche,Charles W. Penn,C. J. Smyth
Publisher : Cambridge University Press
Page : 343 pages
File Size : 51,8 Mb
Release : 1992-10-22
Category : Science
ISBN : 0521432987

Get Book

Molecular Biology of Bacterial Infection by Carlos E. Hormaeche,Charles W. Penn,C. J. Smyth Pdf

Understanding virulence determinants of bacterial pathogens and their regulation, and the pathogenesis of bacterial infections, is essential to the development of safe and effective vaccines and therapeutic strategies. This book presents an authoritative account of the contributions being made by molecular genetics and improved analytical technology in uncovering the molecular basis of bacteria-host interactions in infections. The broad scope of the volume encompasses normal flora and colonization resistance, evolution of pathogenic mechanisms, genetic approaches to understanding bacterial pathogenesis and in vivo studies of mutants, antigenic variation, bacterial invasion, toxins, environmental control of gene expression, regulatory networks in gene control, and attenuation of virulence through auxotrophy. The book will provide a state of the art reference for researchers in all areas concerned with bacterial infection and will also be useful as an advanced text.

Author : Carlos E. Hormaeche,Charles W. Penn,C. J. Smyth
Publisher : Cambridge University Press
Page : 343 pages
File Size : 54,6 Mb
Release : 1992-10-22
Category : Science
ISBN : 0521432987

Get Book

Molecular Biology of Bacterial Infection by Carlos E. Hormaeche,Charles W. Penn,C. J. Smyth Pdf

Understanding virulence determinants of bacterial pathogens and their regulation, and the pathogenesis of bacterial infections, is essential to the development of safe and effective vaccines and therapeutic strategies. This book presents an authoritative account of the contributions being made by molecular genetics and improved analytical technology in uncovering the molecular basis of bacteria-host interactions in infections. The broad scope of the volume encompasses normal flora and colonization resistance, evolution of pathogenic mechanisms, genetic approaches to understanding bacterial pathogenesis and in vivo studies of mutants, antigenic variation, bacterial invasion, toxins, environmental control of gene expression, regulatory networks in gene control, and attenuation of virulence through auxotrophy. The book will provide a state of the art reference for researchers in all areas concerned with bacterial infection and will also be useful as an advanced text.

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 50,7 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

Get Book

Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Abigail A. Salyers,Dixie D. Whitt
Publisher : Unknown
Page : 586 pages
File Size : 43,8 Mb
Release : 2002
Category : Medical
ISBN : UOM:39015054135952

Get Book

Bacterial Pathogenesis by Abigail A. Salyers,Dixie D. Whitt Pdf

Bacterial Pathogenesis: A Molecular Approach is the first text designed to provide a comprehensive introduction to this dynamic field for both students and researchers. The application of molecular techniques to the study of bacterium-host interaction has made possible great progress in fundamental understanding of the molecular basis of infectious diseases. In the text the authors integrate material from pathogenic microbiology, molecular biology, immunology, and human physiology to provide a complete but accessible overview of the field.

Author : Frank R. DeLeo,Michael Otto
Publisher : Springer Science & Business Media
Page : 314 pages
File Size : 55,5 Mb
Release : 2008-01-31
Category : Medical
ISBN : 9781588297402

Get Book

Bacterial Pathogenesis by Frank R. DeLeo,Michael Otto Pdf

Bacterial infections affect world health today as a leading cause of morbidity and mortality. This book presents in-depth methods and state-of-the-art protocols for investigating specific mechanisms of pathogenesis for a wide range of bacteria. Written by experts in the field, this invaluable collection includes protocols to study host-pathogen interactions, animal models of infection, and novel approaches to identifying therapeutic targets designed to control infections.

Author : Jörg Hinrich Hacker,Jürgen Heesemann
Publisher : Wiley-Spektrum
Page : 370 pages
File Size : 40,5 Mb
Release : 2002-10-03
Category : Medical
ISBN : UOM:39015055853728

Get Book

Molecular Infection Biology by Jörg Hinrich Hacker,Jürgen Heesemann Pdf

This comprehensive volume focuses on molecular methods and principles of prokaryotic and eukaryotic pathogens. The authors present the molecular and cellular aspects by focusing on the interactions between pathogenic microorganisms and their hosts. The publication begins with an overview of the most important and dangerous causative agents of infectious diseases. Next are discussions of how microbial "weapons," pathogenicity factors, protein secretion machines, and surface variation systems work, presenting the molecular and genetic methods that are used by scientists for their discovery and analysis. Furthermore, infectious diseases are discussed in light of the newly formed research areas of evolutionary and cellular microbiology and genomics. Future aspects on diagnostic techniques, therapy, and vaccine development are also presented.

Author : Brenda A. Wilson,Malcolm Winkler,Brian T. Ho
Publisher : John Wiley & Sons
Page : 1326 pages
File Size : 47,9 Mb
Release : 2019-07-01
Category : Medical
ISBN : 9781683672883

Get Book

Bacterial Pathogenesis by Brenda A. Wilson,Malcolm Winkler,Brian T. Ho Pdf

This highly anticipated update of the acclaimed textbook draws on the latest research to give students the knowledge and tools to explore the mechanisms by which bacterial pathogens cause infections in humans and animals. Written in an approachable and engaging style, the book uses illustrative examples and thought-provoking exercises to inspire students with the potential excitement and fun of scientific discovery. Completely revised and updated, and for the first time in stunning full-color, Bacterial Pathogenesis: A Molecular Approach, Fourth Edition, builds on the core principles and foundations of its predecessors while expanding into new concepts, key findings, and cutting-edge research, including new developments in the areas of the microbiome and CRISPR as well as the growing challenges of antimicrobial resistance. All-new detailed illustrations help students clearly understand important concepts and mechanisms of the complex interplay between bacterial pathogens and their hosts. Study questions at the end of each chapter challenge students to delve more deeply into the topics covered, and hone their skills in reading, interpreting, and analyzing data, as well as devising their own experiments. A detailed glossary defines and expands on key terms highlighted throughout the book. Written for advanced undergraduate, graduate, and professional students in microbiology, bacteriology, and pathogenesis, this text is a must-have for anyone looking for a greater understanding of virulence mechanisms across the breadth of bacterial pathogens.

Author : Society for General Microbiology. Symposium,M. A. McCrae,Society for General Microbiology
Publisher : Cambridge University Press
Page : 378 pages
File Size : 54,6 Mb
Release : 1997-05-13
Category : Medical
ISBN : 0521592151

Get Book

Molecular Aspects of Host-Pathogen Interactions by Society for General Microbiology. Symposium,M. A. McCrae,Society for General Microbiology Pdf

Reports the latest advances in defining the molecular basis of infection in both bacterial and viral systems.

Author : Brian Henderson
Publisher : John Wiley & Sons
Page : 493 pages
File Size : 41,9 Mb
Release : 2017-04-17
Category : Science
ISBN : 9781118951118

Get Book

Moonlighting Proteins by Brian Henderson Pdf

Moonlighting Proteins: Novel Virulence Factors in Bacterial Infections is a complete examination of the ways in which proteins with more than one unique biological action are able to serve as virulence factors in different bacteria. The book explores the pathogenicity of bacterial moonlighting proteins, demonstrating the plasticity of protein evolution as it relates to protein function and to bacterial communication. Highlighting the latest discoveries in the field, it details the approximately 70 known bacterial proteins with a moonlighting function related to a virulence phenomenon. Chapters describe the ways in which each moonlighting protein can function as such for a variety of bacterial pathogens and how individual bacteria can use more than one moonlighting protein as a virulence factor. The cutting-edge research contained here offers important insights into many topics, from bacterial colonization, virulence, and antibiotic resistance, to protein structure and the therapeutic potential of moonlighting proteins. Moonlighting Proteins: Novel Virulence Factors in Bacterial Infections will be of interest to researchers and graduate students in microbiology (specifically bacteriology), immunology, cell and molecular biology, biochemistry, pathology, and protein science.

Author : S. Myint,A. Cann
Publisher : Springer Science & Business Media
Page : 290 pages
File Size : 47,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789401115308

Get Book

Molecular and Cell Biology of Opportunistic Infections in AIDS by S. Myint,A. Cann Pdf

Human immunodeficiency virus and AIDS have received much attention in the last decade. As the major cause of death in young adults, this concern is merited. AIDS has also ushered onto the clinical agenda a number of unusual and interesting pathogens. These have had considerably less attention than the virus itself, but are arguably as important. This book attempts to put into one volume a state of the art review of the basic biology of these opportunistic organisms. When compiling this book, the perceived difficulty was deciding how to restrict the number of chapters, as there is a large number of opportunistic organisms. It soon became clear, however, that the chapters would select themselves, as the work on many of these organisms was still in its infancy. We can be criticized for including Salmonella, which is not thought to be an opportunistic infection, and excluding Cryptococcus. Our defence is that the former has an interesting relationship with HIV and the latter is one of those organisms for which the basic biology is still in its early stages. The authors are all active researchers in their respective fields and we are grateful that they managed to review their subjects in the short turn-around time required for a book such as this not to be needlessly outdated on publication. We hope that, if nothing else, this book stimulates interest and more research on these agents: perhaps, in future editions, there will be much more to describe on their molecular biology.

Author : Ivano de Filippis,Marian L. McKee
Publisher : Springer Science & Business Media
Page : 475 pages
File Size : 46,7 Mb
Release : 2012-11-07
Category : Science
ISBN : 9781627031851

Get Book

Molecular Typing in Bacterial Infections by Ivano de Filippis,Marian L. McKee Pdf

Molecular Typing in Bacterial Infections covers common bacterial pathogenic agents, with the most effective methods for their identification and classification in the light of their specific epidemiology. The book will be a valuable resource for molecular typing of infectious diseases agents encountered in both the research and hospital clinical lab settings, as well as culture collections. Each chapter provides an overview of molecular approaches to typing bacterial pathogens. Part I gives a general overview of typing methods used in the traditional microbiology laboratory in comparison to molecular methods of epidemiology. In Part II, the relative strengths and weaknesses of the different methods applicable to the specific agents of infectious diseases are emphasized. Specific emphasis is placed on recent changes and updates in molecular typing.

Author : Barbara H. Iglewski
Publisher : Elsevier
Page : 484 pages
File Size : 50,7 Mb
Release : 1990-01-01
Category : Science
ISBN : 9780323148672

Get Book

Molecular Basis of Bacterial Pathogenesis by Barbara H. Iglewski Pdf

Molecular Basis of Bacterial Pathogenesis focuses on the molecular mechanism of disease associated with bacterial pathogens. Topics covered include the population genetics of bacterial pathogenesis; environmental modulation of gene expression in gram-negative pathogens; and bacterial invasion and intracellular growth. Bacterial toxins are also discussed. This volume is comprised of 20 chapters and begins with an overview of pathogenesis, paying particular attention to common elements and genetic mechanisms of regulation. The discovery that many bacterial pathogens are clonal, with individual clones often having a greater virulence than others, is then considered. The next section deals with the regulation of synthesis of surface components and their role in colonization of the host and/or evasion of the host immune defense systems; antigenic variation and its role in evasion of the host immune response; and the role of iron acquisition systems in the colonization of the host. Subsequent chapters explore the invasion and intracellular growth of facultative and obligate intracellular parasites. The last section is devoted to studies on the role of bacterial toxic products in pathogenesis. Bacterial lipopolysaccharides (endotoxins) and exotoxins are described. This book should be of interest to molecular biologists, physiologists, clinical specialists, pathologists, and geneticists.

Author : Muhammad Imran Qadir
Publisher : Bentham Science Publishers
Page : 212 pages
File Size : 47,9 Mb
Release : 2020-09-08
Category : Medical
ISBN : 9789811473746

Get Book

Bacterial Diseases by Muhammad Imran Qadir Pdf

Bacterial Diseases provides readers an overview of a broad variety of bacterial infections. Chapters cover the description of specific disease and its causative agent, followed by information about symptoms, diagnosis and clinical management. This easy-to-read resource is a suitable introductory textbook for pharmacy, medical, and dental students, as well as M Phil, and Ph.D. candidates for Pharmacology, Botany, Zoology, Microbiology, Pharmacy, Biotechnology and allied health science programs. Readers interested in a simple clinical summary of bacterial diseases can also benefit from the information provided. Key Features: - Coverage of a broad spectrum of bacterial infections over 41 topical chapters - Easy-to-read presentation which provides a basic description of diseases covered to clinical diagnosis and management - Emphasis on the route of infection - References for further reading

Author : Jeremy W. Dale,Simon F. Park
Publisher : John Wiley & Sons
Page : 362 pages
File Size : 45,5 Mb
Release : 2004-03-10
Category : Medical
ISBN : 0470850841

Get Book

Molecular Genetics of Bacteria by Jeremy W. Dale,Simon F. Park Pdf

Presenting the basic concepts and most exciting developments, this textbook provides an introduction to the molecular genetics of bacteria in a form suitable for the needs of students studying microbiology, biotechnology, molecular biology, biochemistry, genetics and related biomedical sciences.

Author : Ohad Gal-Mor
Publisher : Unknown
Page : 267 pages
File Size : 40,7 Mb
Release : 2022
Category : Bacteria
ISBN : 1071619713

Get Book

Bacterial Virulence by Ohad Gal-Mor Pdf

This detailed volume explores the field of bacterial virulence and the effort to understand how microbial interaction with a host results in the pathology of a specific disease. This collection of selected protocols includes advanced molecular biology and bioinformatics methods, cell culture and organoid models of infection, as well as in vivo infection models that are useful to study the interaction of pathogens with plants, insects, avian, and mammalian hosts. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and beneficial, Bacterial Virulence: Methods and Protocols serves as an ideal guide for researchers seeking to promote and further develop the exciting and continuously evolving field of bacterial virulence. Chapter 19 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.