Molecular Endocrinology

Author : Franklyn F. Bolander
Publisher : Academic Press
Page : 601 pages
File Size : 44,8 Mb
Release : 2013-10-22
Category : Medical
ISBN : 9781483288215

Get Book

Molecular Endocrinology by Franklyn F. Bolander Pdf

Aimed at graduate level courses, this textbook provides students with a solid background in the basics of molecular endocrinology. Molecular Endocrinology, Second Edition, summarizes the area and provides an in-depth discussion of the molecular aspects of hormone action, including hormone-receptor interactions, second messenger generation, gene induction, and post-transcriptional control. Thoroughly revised and updated, the Second Edition includes new information on growth factors, hematopoietic-immune factors, nonclassical hormones, receptors, transduction, transcriptional regulation, as well as other relevant topics. Incorporating an abundance of new information, this text retains the self-contained, focused, and easily readable style of the First Edition. Professionals in related fields will also find this book to be a helpful summary and general reference source.

Author : Bruce D. Weintraub
Publisher : Lippincott Williams & Wilkins
Page : 552 pages
File Size : 48,8 Mb
Release : 1995
Category : Endocrine glands
ISBN : UOM:39015032316906

Get Book

Molecular Endocrinology by Bruce D. Weintraub Pdf

Author : Gill Rumsby,Dr Sheelagh Farrow
Publisher : Garland Science
Page : 319 pages
File Size : 43,5 Mb
Release : 2020-07-26
Category : Science
ISBN : 9781000144697

Get Book

Molecular Endocrinology by Gill Rumsby,Dr Sheelagh Farrow Pdf

This volume in the Human Molecular Genetics series is an invaluable text for endocrinologists wishing to update their knowledge. It also provides an excellent grounding in the basic genetics of molecular endocrinology and relevant analytical techniques.

Author : Jonathan C. Schisler,Charles H Lang,Monte Willis
Publisher : Academic Press
Page : 378 pages
File Size : 49,9 Mb
Release : 2016-10-19
Category : Medical
ISBN : 9780128031124

Get Book

Endocrinology of the Heart in Health and Disease by Jonathan C. Schisler,Charles H Lang,Monte Willis Pdf

Endocrinology of the Heart in Health and Disease: Integrated, Cellular, and Molecular Endocrinology of the Heart covers the traditional concepts of cardio-endocrinology, the role of the various hormone systems, both in health and disease, therapeutic implications, and other recent advances in the various fields represented. The book explores how cardiac hormones are changed in various cardiac pathologies and the recent success that has been uncovered in their therapeutic use. Additional focus is placed on how the heart responds both physiologically and pathophysiologically to a plethora of circulating hormones, reinforcing the importance of the heart as a target of numerous endocrine systems, such as the brain, renal, and adipose. Significant advances have come from basic, clinical, and translational research from a multiplicity of investigators with diverse backgrounds. The book features over 200 photomicrographs, diagrams of molecular relationships, and tables that complement and support the text. It is aimed at a wide audience, including graduate students and post-doctoral fellows in a wide array of biomedical departments and PhD programs (e.g. Pathology, Physiology, Genetics, Pharmacology, Molecular Biology, and Cell Biology) related to the endocrine and cardiovascular sciences curricula, as well as medical residents in pathology, laboratory medicine, internal medicine, and cardiology. Develops the concept of the heart as both an endocrine organ and an endocrine target, exploring the endocrine function of the heart in both health and disease Explains how the levels of several cardiac hormones are changed in various cardiac pathologies and how some hormones can be used therapeutically Offers a single resource on cardio-endocrine disease which collates and curates the wide range of advances being made in the areas of molecular biology, biochemistry, physiology, and pathology

Author : Franklyn Bolander
Publisher : Elsevier
Page : 328 pages
File Size : 45,5 Mb
Release : 2012-12-02
Category : Nature
ISBN : 9780323155762

Get Book

Molecular Endocrinology by Franklyn Bolander Pdf

Molecular Endocrinology examines basic principles in molecular endocrinology using selected examples. It looks at the molecular aspects of hormone action, from hormone-receptor interactions to second messenger generation, gene induction, and post-transcriptional control. It also explores the regulation of nuclear receptors and membrane receptors, the nontranscriptional effects of hormones, the modifications of histone and nonhistone protein, the molecular evolution of the endocrine system, and the molecular bases of endocrinopathies. Organized into five sections comprised of 16 chapters, this book begins with a brief summary of general endocrinology and then discusses the basic characteristics of hormones and their regulation, illustrated by the hormonal control of calcium metabolism. It explains other major endocrine systems, including the hypothalamus, pituitary gland, and thyroid gland. The remainder of the text focuses on receptors and how to determine their number and affinity; the structure, function, and metabolism of nuclear and membrane receptors; the mechanisms for the regulation of receptor activity; the major second messengers, such as cyclic nucleotides, and how they can directly affect cellular processes; the role of phospholipids in signal transduction; mediators such as polyamines, oligosaccharides, and the cytoskeleton; the mechanisms by which hormones and their second messengers affect gene expression; and the hormonal control of various post-transcriptional events. This book will be of interest to biologists and those working in the field of molecular endocrinology.

Author : Jonathan Waxman
Publisher : Cambridge University Press
Page : 450 pages
File Size : 41,7 Mb
Release : 1996-01-26
Category : Medical
ISBN : 0521460670

Get Book

Molecular Endocrinology of Cancer: Volume 1, Part 2, Endocrine Therapies by Jonathan Waxman Pdf

One third of human cancers have a hormonal basis. Breast cancer, the most common cancer of women, is increasing in incidence in many countries, as, in epidemic proportions, is prostate cancer, the second most common cancer of men. Concurrently, the development of molecular biology has led to a refinement of the definition of hormones to include the complex interaction between tumour cells and both locally and distantly secreted factors. This 1996 volume from the series Cancer: Clinical Science in Practice considers the many aspects of hormonally dependent cancer, including the molecular basis for the autocrine and paracrine regulation of cancer, molecular strategies for cancer detection, preventive strategies in limiting the epidemic of hormonally related cancers, and treatment approaches. The concise volumes in this series are intended for a wide audience of clinicians and researchers with an interest in the application of biomedical science to the understanding and management of cancer.

Author : Jitendra Kumar Sundaray,Mohd Ashraf Rather,Sujit Kumar,Deepak Agarwal
Publisher : Springer Nature
Page : 367 pages
File Size : 45,7 Mb
Release : 2021-01-27
Category : Science
ISBN : 9789811583698

Get Book

Recent updates in molecular Endocrinology and Reproductive Physiology of Fish by Jitendra Kumar Sundaray,Mohd Ashraf Rather,Sujit Kumar,Deepak Agarwal Pdf

This book is dedicated to present different aspects of reproductive physiology and molecular endocrinology of commercially important as well as potential aquaculture fish species. The existing aquaculture generation is looking for species diversification for efficient utilization of available diverse water resources. The knowledge of reproductive physiology of fish will help in development of breeding strategy for use in commercial aquaculture. Reproductive system is highly coordinated and governed by means of complex network of nervous, endocrine system and environmental factor as well. This book emphasize on different key aspects of reproductive endocrine system such as basic gonadal biology in the events of climate vulnerability, sex determination, sex reversal, stimulatory hormones, inhibitory hormones and receptors, environmental and chemical factor guiding reproduction, puberty, neuroendocrine regulation of reproduction etc. This book further describes how reproduction is not just indispensable for the existence or survival of an individual, but it is important for the survival of species. Chapters also address the concerns of anthropogenic activities on fish and the aquatic environment lead main trouble on physiological and reproductive processes of aquatic animals. This book offers an attractive compilation of highly relevant aspects of current and future of aquaculture, especially in view of the growing awareness of aquaculture, to food scientists working on commercial fish, animal biologists, fish geneticists etc. This book is very timely, and relevant to the sustainable development goals. The contents would be relevant to policy makers, working towards blue revolution and blue economy.

Author : E. Edward Bittar,Neville Bittar
Publisher : Elsevier
Page : 357 pages
File Size : 52,5 Mb
Release : 1997
Category : Electronic books
ISBN : 9781559388153

Get Book

Molecular and Cellular Endocrinology by E. Edward Bittar,Neville Bittar Pdf

Molecular and Cell Endocrinology.

Author : Anonim
Publisher : Academic Press
Page : 518 pages
File Size : 51,8 Mb
Release : 1994-12-23
Category : Science
ISBN : 008058537X

Get Book

Molecular Endocrinology of Fish by Anonim Pdf

Hormones have a manifold impact upon growth and metabolism. This book focuses upon the molecular biology of fish hormones and their regulation. Chapters dealing with gonadotropin, corticotropin, vasotocin, isotocin, somatolactin, and other hormones are written by an international team of fish physiologists and endocrinologists. In addition, there are chapters that survey a growing literature on the ways hormones are regulated both in terms of their actions and in terms of the gene transcription that leads to their formation. The first two sections of the book covers brain and pituitary hormones and the latter two sections are devoted to other hormones and their regulation. As more and more endocrinologists and physiologists seek to use hormones that are inexpensive, provide for more facile experimental replication, and are less subject to cumbersome regulation, they will turn to the sorts of fish models reviewed in this book.

Author : Ok-Kyong Park-Sarge,Thomas E. Curry, Jr.
Publisher : Humana Press
Page : 0 pages
File Size : 45,9 Mb
Release : 2012-02-25
Category : Medical
ISBN : 1617796689

Get Book

Molecular Endocrinology by Ok-Kyong Park-Sarge,Thomas E. Curry, Jr. Pdf

Over the course of the last hundred years, the field of endocrinology has received ever-increasing attention. Research and developing technologies have resulted in a significant leap in our understanding of the causes and treatment of endocrine dysfunction. In Molecular Endocrinology: Methods and Protocols, leaders in the field share a diversity of cutting-edge techniques that are becoming routinely employed in the quest to further understand hormone action. In order to reach the widest number of labs, this volume includes protocols that allow investigators at all stages of their scientific career to successfully perform these techniques. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include brief introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and expert notes on troubleshooting and avoiding known pitfalls. Comprehensive and easy to use, Molecular Endocrinology: Methods and Protocols is an ideal guide for researchers in labs across the world who seek a deeper understanding of the complex processes and biology of hormones.

Author : D. LeRoith
Publisher : Elsevier
Page : 269 pages
File Size : 54,8 Mb
Release : 1997-03-25
Category : Medical
ISBN : 0080526381

Get Book

Advances in Molecular and Cellular Endocrinology by D. LeRoith Pdf

Historically the field of endocrine research has always been at the forefront of scientific endeavors. The investigators of these important breakthroughs in research have been rewarded by numerous Nobel awards. In the field of diabetes alone, Nobel prizes have been awarded to researchers who discovered insulin, characterized the protein and invented radioimmunoassays using insulin as a paradigm. Not surprisingly, biomedical researchers have always been attracted by the endocrine system and other similar systems of intercellular communication. Over the past two decades, endocrine research has developed rapidly and adapted modern molecular and cellular biology techniques for its specific use. These changes have allowed researchers in the field to maintain their edge. Thus, endocrine disease-related genes have been characterized and mutations in these genes have helped explain common and less common endocrine disorders. Our understanding of the regulation of gene expression has been greatly enhanced by molecular techniques. In an attempt to bring investigators up to date with the recent advances in this exploding field we have decided to publish a series entitled Advances in Molecular and Cellular Endocrinology. Internationally famous investigators have agreed to participate and their contributions are appreciated. Volume 1 has focused on aspects of the hypothalamic-pituitary axis including GnRH and GH gene regulation, molecular aspects of insulin, insulin-like growth factors and glucagon. In addition, reviews on the recently cloned calcium receptor and steroid receptor interactions with DNA are presented.

Author : Alfredo Ulloa-Aguirre,Ya-Xiong Tao
Publisher : Academic Press
Page : 488 pages
File Size : 40,9 Mb
Release : 2021-02-02
Category : Science
ISBN : 9780128198025

Get Book

Cellular Endocrinology in Health and Disease by Alfredo Ulloa-Aguirre,Ya-Xiong Tao Pdf

Cellular Endocrinology in Health and Disease, Second Edition, describes the underlying basis of endocrine function, providing an important tool to understand the fundamentals of endocrine diseases. Delivering a comprehensive review of the basic science of endocrinology, from cell biology to human disease, this work explores and dissects the function of a number of cellular systems. The new edition provides an understanding of how endocrine glands function by integrating information resulting in biological effects on both local and systemic levels, also providing new information on the molecular physiopathogenesis of endocrine neoplasic cells. The new edition expands the most used chapters from the first edition and proposes a series of substitutions and additions to the table of contents. New chapters cover signaling, brown adipose tissue, hypothalamic cell models, cellular basis of insulin resistance, genetics and epigenetics of neuroendocrine tumors, and a series of chapters on endocrine-related cancer. Providing content that crosses disciplines, Cellular Endocrinology in Health and Disease, Second Edition, details how cellular endocrine function contributes to system physiology and mediates endocrine disorders. A methods section proves novel and useful approaches across research focus that will be attractive to medical students, residents, and specialists in the field of endocrinology, as well as to those interested in cellular regulation. Editors Alfredo Ulloa-Aguirre and Ya-Xiong Tao, experts in molecular and cellular aspects of endocrinology, deliver contributions carefully selected for relevance, impact, and clarity of expression from leading field experts Explores endocrine cells biology in normal and pathologic conditions Covers new aspects of endocrine cell function in distinct tissues Provides a view into the biological effect in local and systemic levels 15 new chapters covering the recent developments in the field

Author : P. Jorge Chedrese
Publisher : Springer Science & Business Media
Page : 355 pages
File Size : 45,8 Mb
Release : 2009-06-13
Category : Medical
ISBN : 9780387881867

Get Book

Reproductive Endocrinology by P. Jorge Chedrese Pdf

Molecular biology emerged from advances in biochemistry during the 1940s and 1950s, when the structure of the nucleic acids and proteins were elucidated. Beginning in the 1970s, with nucleic acid enzymology and the discovery of the restriction enzymes, the tools of molecular biology became widely available and applied in cell biology to study how genes are regulated. This new knowledge impacted endocrinology and reproductive biology since it was largely known that the secretion of the internal glands affected the phenotypes, and expression of genes. Modern reproductive biology encompasses every level of biological study from genomics to ecology, encompassing cell biology, biochemistry, endocrinology and general physiology. All of these disciplines require a basic knowledge, both as a tool and as an essential aid to a fundamental understanding of the principles of life in health and disease. Overall, molecular biology is central to scientific studies in all living matter, impacting disciplines such as medicine, related health sciences, veterinary, agriculture and environmental sciences. In this book, the basic biochemistry of nucleic acids and proteins are reviewed. Methodologies used to study signaling and gene regulation in the endocrine/reproductive system are also discussed. Topics include mechanisms of hormone action and several endocrine disorders affecting the reproductive system. Professionals in the medical, veterinary and animal sciences fields will find exciting and stimulating material enhancing the breadth and quality of their research.

Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 51,5 Mb
Release : 1975
Category : Electronic
ISBN : OCLC:165024879

Get Book

Molecular Endocrinology by Anonim Pdf

Author : Stuart Handwerger
Publisher : Springer Science & Business Media
Page : 318 pages
File Size : 51,8 Mb
Release : 1999-02-26
Category : Medical
ISBN : 9781592596973

Get Book

Molecular and Cellular Pediatric Endocrinology by Stuart Handwerger Pdf

Stuart Handwerger, MD and a distinguished panel of clinicians and experts review the most significant recent developments in molecular and cellular biology, powerful advances that have produced new diagnostic methods and improved treatments for many pediatric endocrine diseases. Topics range from the growth hormone/prolactin/placental lactogen gene family and their regulation of growth, to steroid hormones, sexual development, and mineral corticoid action. Additional chapters examine the pathophysiology of insulin-dependent diabetes mellitus, the molecular genetics of thyroid cancer, the molecular basis of hypophosphatemic rickets, and inherited diabetes insipidus. Molecular and Cellular Pediatric Endocrinology offers today's clinicians and researchers not only the latest findings on endocrine diseases in their pediatric manifestations, but also highly practical insights into today's cutting-edge diagnostics, treatment strategies, and powerful new therapeutics.