Molecular Neurology

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Molecular Neurology

Stephen Waxman
Molecular Neurology Book PDF

Author : Stephen Waxman
Publisher : Elsevier
Page : 600 pages
File Size : 44,6 Mb
Release : 2010-07-26
Category : Medical
ISBN : 0080546188

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Molecular Neurology by Stephen Waxman Pdf

Why a book on molecular neurology? Molecular neuroscience is advancing at a spectacular rate. As it does so, it is revealing important clues to the pathogenesis and pathophysiology of neurological diseases, and to the therapeutic targets that they present. Medicines work by targeting molecules. The more specific the targeting, the more specific the actions, and the fewer the side effects. Molecular Neurology highlights, for graduate and MD-PhD students, research fellows and research-oriented clinical fellows, and researchers in the neurosciences and other biomedical sciences, the principles underlying molecular medicine as related to neurology. Written by internationally recognized experts, this well-illustrated and well-referenced book presents the most up-to-date principles and disease examples relevant to molecular neurology, and reviews the concepts, strategies, and latest progress in this field. This book will interest anyone studying the molecular basis of neurology, or developing new therapies in neurology. Describes the newest molecular aspects of neurological disorders Provides an introduction to neurological disorders for basic scientists Updates clinicians and clinical researchers on the most recent developments

Basic Neurochemistry

Scott Brady,George Siegel,R. Wayne Albers,Donald Price
Basic Neurochemistry Book PDF

Author : Scott Brady,George Siegel,R. Wayne Albers,Donald Price
Publisher : Academic Press
Page : 1120 pages
File Size : 49,9 Mb
Release : 2011-11-02
Category : Science
ISBN : 9780080959016

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Basic Neurochemistry by Scott Brady,George Siegel,R. Wayne Albers,Donald Price Pdf

Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology, the outstanding and comprehensive classic text on neurochemistry, is now newly updated and revised in its Eighth Edition. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences. The text has evolved, as intended, with the science. It is also an excellent source of current information on basic biochemical and cellular processes in brain function and neurological diseases for continuing medical education and qualifying examinations. This text continues to be the standard reference and textbook for exploring the translational nature of neuroscience, bringing basic and clinical neuroscience together in one authoritative volume. Our book title reflects the expanded attention to these links between neurochemistry and neurologic disease. This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from: Intracellular trafficking; Stem cells, adult neurogenesis, regeneration; Lipid messengers; Expanded coverage of all major neurodegenerative and psychiatric disorders; Neurochemistry of addiction; Neurochemistry of pain; Neurochemistry of hearing and balance; Neurobiology of learning and memory; Sleep; Myelin structure, development, and disease; Autism; and Neuroimmunology. Completely updated text with new authors and material, and many entirely new chapters Over 400 fully revised figures in splendid color 61 chapters covering the range of cellular, molecular and medical neuroscience Translational science boxes emphasizing the connections between basic and clinical neuroscience Companion website at http://elsevierdirect.com/companions/9780123749475

From Neuroscience to Neurology

Stephen Waxman
From Neuroscience to Neurology Book PDF

Author : Stephen Waxman
Publisher : Elsevier
Page : 552 pages
File Size : 46,8 Mb
Release : 2004-11-05
Category : Medical
ISBN : 9780080506982

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From Neuroscience to Neurology by Stephen Waxman Pdf

The field of neurology is being transformed, from a therapeutically nihilistic discipline with few effective treatments, to a therapeutic specialty which offers new, effective treatments for disorders of the brain and spinal cord. This remarkable transformation has bridged neuroscience, molecular medicine, and clinical investigation, and represents a major triumph for biomedical research. This book, which contains chapters by more than 29 internationally recognized authorities who have made major contributions to neurotherapeutics, tells the stories of how new treatments for disabling disorders of the nervous system, such as stroke, multiple sclerosis, Parkinson’s disease, and migraine, were developed, and explores evolving themes and technologies that offer hope for even more effective treatments and ultimately cures for currently untreatable disorders of the brain and spinal cord. The first part of this book reviews the development of new therapies in neurology, from their inception in terms of basic science to their introduction into the clinical world. It also explores evolving themes and new technologies. This book will be of interest to everyone – clinicians and basic scientists alike – interested in diseases of the brain and spinal cord, and in the quest for new treatments for these disorders. * Presents the evolution of the field of neurology into a therapeutic discipline * Discusses lessons learned from past successes and applications to ongoing work * Explores the future of this field

Neurogenetics in Neurology: From Molecular Neuroscience to Precision Medicine

Matthew James Farrer,Guy Rouleau
Neurogenetics in Neurology From Molecular Neuroscience to Precision Medicine Book PDF

Author : Matthew James Farrer,Guy Rouleau
Publisher : Frontiers Media SA
Page : 106 pages
File Size : 40,8 Mb
Release : 2020-12-22
Category : Medical
ISBN : 9782889662517

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Neurogenetics in Neurology: From Molecular Neuroscience to Precision Medicine by Matthew James Farrer,Guy Rouleau Pdf

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Molecular Neuroscience

Patricia Revest,Alan Longstaff
Molecular Neuroscience Book PDF

Author : Patricia Revest,Alan Longstaff
Publisher : Garland Science
Page : 258 pages
File Size : 43,9 Mb
Release : 1998
Category : Anatomy
ISBN : 9781859962503

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Molecular Neuroscience by Patricia Revest,Alan Longstaff Pdf

This textbook provides an introduction to neuroscience, focusing particularly on the rapidly developing molecular aspects. The techniques of molecular biology are introduced and described in the context of their role in elucidating brain function at the molecular level.

Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease

Roger N. Rosenberg,Juan M. Pascual
Rosenberg s Molecular and Genetic Basis of Neurological and Psychiatric Disease Book PDF

Author : Roger N. Rosenberg,Juan M. Pascual
Publisher : Academic Press
Page : 1013 pages
File Size : 43,6 Mb
Release : 2020-06-24
Category : Medical
ISBN : 9780128139561

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Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease by Roger N. Rosenberg,Juan M. Pascual Pdf

Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Sixth Edition: Volume One, provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to neurologic and psychiatric disease. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the neuroscience and neurology research community. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling. Every chapter has been thoroughly revised or newly commissioned to reflect the latest scientific and medical advances by an international team of leading scientists and clinicians. The contents have been expanded to include disorders for which a genetic basis has been recently identified, together with abundant original illustrations that convey and clarify the key points of the text in an attractive, didactic format. Comprehensive coverage of the neurogenetic foundation of neurological and psychiatric disease Provides a detailed introduction on both the clinical and basic research implications of molecular and genetics surrounding the brain Includes new chapters on molecular genomics, CRISPR and the most recent updates in molecular genetics

The Molecular and Genetic Basis of Neurologic and Psychiatric Disease

Roger N. Rosenberg
The Molecular and Genetic Basis of Neurologic and Psychiatric Disease Book PDF

Author : Roger N. Rosenberg
Publisher : Lippincott Williams & Wilkins
Page : 930 pages
File Size : 40,8 Mb
Release : 2008
Category : Medical
ISBN : 0781769566

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The Molecular and Genetic Basis of Neurologic and Psychiatric Disease by Roger N. Rosenberg Pdf

Completely updated for its Fourth Edition, this book is the most comprehensive, current review of the molecular and genetic basis of neurologic and psychiatric diseases. More than 120 leading experts provide a fresh, new assessment of recent molecular, genetic, and genomic advances, offer new insights into disease pathogenesis, describe the newest available therapies, and explore promising areas of therapeutic development. This edition features an updated section on psychiatric disease and expanded, updated chapters on human genomics, gene therapy, and ethical issues. Six new chapters cover congenital myasthenic syndromes, hereditary spastic paraplegia, ion channel disorders, the phakomatoses, beta-galactosidase deficiency, and prion diseases. A Neurologic Gene Map describes the chromosome locus of all the genetic diseases and their gene product where known. The fully searchable online text will be available on a companion Website. (www.rosenbergneuroandpsychdisease.com)

Cellular and Molecular Methods in Neuroscience Research

Adalberto Merighi,Giorgio Carmignoto
Cellular and Molecular Methods in Neuroscience Research Book PDF

Author : Adalberto Merighi,Giorgio Carmignoto
Publisher : Springer Science & Business Media
Page : 307 pages
File Size : 41,9 Mb
Release : 2007-12-14
Category : Medical
ISBN : 9780387224602

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Cellular and Molecular Methods in Neuroscience Research by Adalberto Merighi,Giorgio Carmignoto Pdf

There are numerous books on cellular and molecular protocols for general use in cell biology but very few are exclusively devoted to neurobiology. This book fills this gap and explains in a clear and consistent manner, some of the more commonly used protocols in neuroscience research. Each chapter is written by either the person who invented the procedure or an expert in the field. The format is uniform: "Overview," "Background," "Protocols," and "results and discussion." Each protocol begins with the principle of the technique, studies in cell culture, materials and reagents, and, lastly, step-by-step outline of the procedure itself. This highly practical book is also well illustrated (with 17 four color plates) to make the concepts and procedures easy to understand and perform.

Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease

Roger N. Rosenberg,Juan M. Pascual
Rosenberg s Molecular and Genetic Basis of Neurological and Psychiatric Disease Book PDF

Author : Roger N. Rosenberg,Juan M. Pascual
Publisher : Elsevier
Page : 1464 pages
File Size : 52,5 Mb
Release : 2014-10-28
Category : Medical
ISBN : 9780124105492

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Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease by Roger N. Rosenberg,Juan M. Pascual Pdf

Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Fifth Edition provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to the majority of neurologic and psychiatric disease. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the neuroscience and neurology research community. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling. Every chapter has been thoroughly revised or newly commissioned to reflect the latest scientific and medical advances by an international team of leading scientists and clinicians. The contents have been expanded to include disorders for which a genetic basis has been recently identified, together with abundant original illustrations that convey and clarify the key points of the text in an attractive, didactic format. Previous editions have established this book as the leading tutorial reference on neurogenetics. Researchers will find great value in the coverage of genomics, animal models and diagnostic methods along with a better understanding of the clinical implications. Clinicians will rely on the coverage of the basic science of neurogenetics and the methods for evaluating patients with biochemical abnormalities or gene mutations, including links to genetic testing for specific diseases. Comprehensive coverage of the neurogenetic foundation of neurological and psychiatric disease Detailed introduction to both clinical and basic research implications of molecular and genetic understanding of the brain Detailed coverage of genomics, animal models and diagnostic methods with new coverage of evaluating patients with biochemical abnormalities or gene mutations

Molecular Physiology and Metabolism of the Nervous System

Gary A. Rosenberg
Molecular Physiology and Metabolism of the Nervous System Book PDF

Author : Gary A. Rosenberg
Publisher : OUP USA
Page : 241 pages
File Size : 54,9 Mb
Release : 2012-04-30
Category : Medical
ISBN : 9780195394276

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Molecular Physiology and Metabolism of the Nervous System by Gary A. Rosenberg Pdf

The molecular basis for the physiology of the brain has advanced enormously in the past twenty years with an influx of new information gleaned through technological developments in neuroimaging and molecular discoveries. Molecular Physiology and Metabolism of the Nervous System, authored by Gary A. Rosenberg, an authority on the physiology of brain fluids and metabolism, combines the classic physiology that dates back to the beginning of the nineteenth century with the advances in molecular sciences, providing a strong framework for understanding the diseases that are commonly treated by neurologists. Molecular Physiology and Metabolism of the Nervous System focuses on the current neuropathology and implications of cerebrospinal fluid diseases and diseases of the blood-brain barrier: how the two affect stroke, infection, brain tumors, and increased intracranial pressure. The book discusses the effects of blood flow in stroke and dementia, the disruption of the blood-brain barrier in neuroinflammation, and the dysfunction due to brain edema and increased intracranial pressure. Molecular Physiology and Metabolism of the Nervous System is necessary reading for neurologists, neuroscientists, and residents in neurology, neurosurgery, and psychiatry, giving them a strong grounding in physiology and metabolism that will aid them in diagnosis and treatment.

Molecular Biology of Neurodegenerative Diseases: Visions for the Future - Part B

Anonim
Molecular Biology of Neurodegenerative Diseases Visions for the Future Part B Book PDF

Author : Anonim
Publisher : Academic Press
Page : 222 pages
File Size : 44,8 Mb
Release : 2021-01-14
Category : Science
ISBN : 9780128241448

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Molecular Biology of Neurodegenerative Diseases: Visions for the Future - Part B by Anonim Pdf

Molecular Biology of Neurodegenerative Diseases: Visions for the Future, Part B, Volume 177 in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. The series includes in-depth knowledge on the molecular biological aspects of organismal physiology, with this release including chapters on Alzheimer's disease, Prion-like propagation of alpha-synuclein, What - if anything - can we learn about neurodegenerative diseases from yeast?, Mitochondrial rejuvenation and replacement as a novel strategy for treatment of age-related neurodegenerative diseases, and more. Includes comprehensive coverage of molecular biology Presents ample use of tables, diagrams, schemata and color figures to enhance the reader's ability to rapidly grasp the information provided Contains contributions from renowned experts in the field

Molecular Neuroscience

David Allan Carter,David Murphy
Molecular Neuroscience Book PDF

Author : David Allan Carter,David Murphy
Publisher : Prentice Hall
Page : 201 pages
File Size : 45,7 Mb
Release : 1999-01
Category : Medical
ISBN : 0582357020

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Molecular Neuroscience by David Allan Carter,David Murphy Pdf

Molecular Neuroscience is a dynamic area of contemporary research which seeks to apply new molecular biology techniques to advance our understanding of complex brain functions such as memory and of inherited neurological diseases such as Alzheimer's. Mammalian genome sequencing projects are building a vast resource which must eventually be integrated into our understanding of the brain, and the new sciences of bioinformatics and functional genomics hold the promise that this integration can become a reality. This readable introduction to the field captures the excitement of current research in the area. Molecular Neuroscience has been developed from final year undergraduate and postgraduate courses, which the authors have devised and taught. It will be of value to advanced university students and to research workers: both to neuroscientists who are adopting molecular approaches for the first time and to those already in the field.

Applications of Biotechnology in Neurology

Kewal K. Jain
Applications of Biotechnology in Neurology Book PDF

Author : Kewal K. Jain
Publisher : Springer Science & Business Media
Page : 638 pages
File Size : 55,6 Mb
Release : 2013-01-05
Category : Medical
ISBN : 9781627032728

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Applications of Biotechnology in Neurology by Kewal K. Jain Pdf

Culling together excerpts from a wide range of writings by Dr. Kewal K. Jain on biotechnology topics as they relate to disorders of the nervous system, Applications of Biotechnology in Neurology covers a variety of applications for those working in life sciences and the pharmaceutical sciences, particularly those developing diagnostics and therapeutics for the nervous system. This detailed volume delves into areas such as neurobiotechnology, like neurogenomics and neuroproteomics, molecular diagnostics, various methods of improving systemic administration of drugs for targeted delivery to the nervous system, including the use of nanobiotechnology, biotechnology-based strategies and products for neuroprotection, as well as chapters on neurosurgery and personalized neurology. Thorough, cutting-edge, and thoughtfully organized, Applications of Biotechnology in Neurology serves as an ideal guide, supplemented by 75 tables and 16 figures as well as numerous references from recent literature on this topic, which are appended to each chapter.

Molecular, Cellular and Model Organism Approaches for Understanding the Basis of Neurological Disease

Robert J. Harvey,Kirsten Harvey
Molecular Cellular and Model Organism Approaches for Understanding the Basis of Neurological Disease Book PDF

Author : Robert J. Harvey,Kirsten Harvey
Publisher : Frontiers Media SA
Page : 185 pages
File Size : 53,8 Mb
Release : 2017-07-05
Category : Electronic book
ISBN : 9782889451739

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Molecular, Cellular and Model Organism Approaches for Understanding the Basis of Neurological Disease by Robert J. Harvey,Kirsten Harvey Pdf

The advent of next-generation sequencing technologies has resulted in a remarkable increase our understanding of human and animal neurological disorders through the identification of disease causing or protective sequence variants. However, in many cases, robust disease models are required to understand how changes at the DNA, RNA or protein level affect neuronal and synaptic function, or key signalling pathways. In turn, these models may enable understanding of key disease processes and the identification of new targets for the medicines of the future. This e-book contains original research papers and reviews that highlight either the impact of next-generation sequencing in the understanding of neurological disorders, or utilise molecular, cellular, and whole-organism models to validate disease-causing or protective sequence variants.

Molecular Neuroscience

Rusty Lansford
Molecular Neuroscience Book PDF

Author : Rusty Lansford
Publisher : Unknown
Page : 0 pages
File Size : 46,8 Mb
Release : 2014
Category : Genes
ISBN : 1621820149

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Molecular Neuroscience by Rusty Lansford Pdf

A wide variety of powerful molecular techniques have been applied to biology in recent decades, ranging from recombinant DNA technologies to state-of-the-art imaging methods. But the plethora of techniques available combined with the complexities of neurobiological systems can make it difficult for neuroscientists to select and carry out an experimental procedure to effectively address the question at hand. This laboratory manual serves as a comprehensive practical guide to molecular and cellular methods for neuroscientists. It consists of five major sections: Working with Cells, Working with DNA, Working with RNA, Gene Transfer, and Imaging. Each includes step-by-step protocols and discussions of basic and cutting-edge procedures for working in that area. Fundamental techniques include maintaining a sterile working environment, purifying and culturing neural cells, isolating and manipulating DNA and RNA, and understanding and using a microscope. Advanced topics include single-neuron isolation and analysis, in vivo gene delivery and imaging, optogenetics, RNA interference, transgenic technologies, high-throughput analysis of gene expression (e.g., RNA-Seq), and constructing and imaging fluorescent proteins. The manual includes protocols developed in the Advanced Techniques in Molecular Neuroscience course offered annually at Cold Spring Harbor Laboratory, as well as protocols drawn from its best-selling lab manuals. It is an essential resource for all neuroscientists, from graduate students upward, who seek to use molecular techniques to probe the complexities of the nervous system.