Molecular Pathogenesis Of Neisseria Gonorrhoeae

Author : Cynthia N Cornelissen
Publisher : Frontiers E-books
Page : 117 pages
File Size : 55,5 Mb
Release : 2024-07-01
Category : Electronic
ISBN : 9782889190089

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Molecular Pathogenesis of Neisseria Gonorrhoeae by Cynthia N Cornelissen Pdf

This Research Topic is dedicated to our current understanding of the molecular pathogenesis of Neisseria gonorrhoeae. Topics in this issue include the following: human infection models for testing gonococcal virulence, animal models that mimic lower female genital tract infection, and an ex vivo system derived from the human female lower genital tract. Vaccine development efforts, and the impact of gonococcal infection on the host's immune response are also described. Also part of this issue are reviews of the molecular aspects of several important virulence factors, including: biofilm formation, neutrophil resistance, innate immune factor resistance, iron acquisition, and type 4 secretion systems.

Author : C. A. Genco,Lee M. Wetzler
Publisher : Caister Academic Press Limited
Page : 0 pages
File Size : 49,8 Mb
Release : 2010
Category : Science
ISBN : 1904455514

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Neisseria by C. A. Genco,Lee M. Wetzler Pdf

This important book provides research scientists, advanced students, clinicians, and other professionals with a comprehensive update on the current understanding of the molecular mechanisms of pathogenesis in Neisseria. Neisseria gonorrhoeae and Nesseria meningitidis are Gram-negative diplococci. N. gonorrhoeae is the causative agent of gonorrhoeae and is transmitted via sexual contact. N. meningitidis is transmitted via respiratory droplets leading to colonization of the nasopharynx and can cause meningitis and septicemia. The book describes the latest, up-to-date research, theory, and clinical significance of molecular mechanisms in meningococcal disease. Leading authorities have contributed chapters on topics such as gene expression, genomics, biofilms, denitrification, adhesion strategies, and mechanisms of cellular invasion. A section on the host response to neisserial infection covers inate immunity, complement, apoptosis, and acquired immunity, while a section devoted to clinical correlation deals with vaccine development, epidemiology, and antibiotic resistance. The book is highly recommended for microbiologists, epidemiologists, and clinicians involved with Neisseria research or meningococcal disease, and it is a recommended text for all microbiology libraries.

Author : John K. Davies (Microbiologist),Charlene M. Kahler
Publisher : Caister Academic Press Limited
Page : 0 pages
File Size : 42,7 Mb
Release : 2014
Category : Gonorrhea
ISBN : 1908230479

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Pathogenic Neisseria by John K. Davies (Microbiologist),Charlene M. Kahler Pdf

The human pathogens Neisseria meningitidis and Neisseria gonorrhoeae are exquisitely adapted to life within the human mucosa, their only natural niche. N. meningitidis is the causative agent of rapidly transmissible meningitis and septic shock. Vaccines developed to control this pathogen can be rendered ineffective by the pathogen's ability to undergo antigenic variation. In contrast, there are no current vaccination prospects for N. gonorrhoeae, the causative agent of sexually transmitted gonorrhoea. Historically, infections caused by N. gonorrhoeae were treated with antibiotics. However, the recent advent of new strains with resistance to all known antibiotics is causing such treatment regimes to fail, necessitating the need for new and more effective control strategies. In this book, leading Neisseria authorities review the most important research on pathogenic Neisseria to provide a timely overview of the field. The topics covered include: the link between pathogenesis and important metabolic pathways * vaccine development * antibiotic resistance * transcriptomics of regulatory networks * regulatory small RNAs * interactions with neutrophils * advances in humanized mouse models. An essential guide for research scientists, advanced students, clinicians, and other professionals working with Neisseria, the book is a recommended text for all microbiology libraries.

Author : Myron Christodoulides
Publisher : Unknown
Page : 461 pages
File Size : 42,9 Mb
Release : 2019
Category : Neisseria gonorrhoeae
ISBN : 1493994964

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Neisseria Gonorrhoeae by Myron Christodoulides Pdf

Author : Richard Bryant Roberts
Publisher : John Wiley & Sons
Page : 456 pages
File Size : 41,6 Mb
Release : 1977
Category : Gonorrhea
ISBN : UOM:39015000256845

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The Gonococcus by Richard Bryant Roberts Pdf

Author : Sebastian G. B. Amyes
Publisher : OUP Oxford
Page : 130 pages
File Size : 49,6 Mb
Release : 2013-05-30
Category : Medical
ISBN : 9780191654084

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Bacteria: A Very Short Introduction by Sebastian G. B. Amyes Pdf

Bacteria form a fundamental branch of life. They are the oldest forms of life as we know it, and they are still the most prolific living organisms. They inhabit every part of the Earth's surface, its ocean depths, and even terrains such as boiling hot springs. They are most familiar as agents of disease, but benign bacteria are critical to the recycling of elements and all ecology, as well as to human health. In this Very Short Introduction, Sebastian Amyes explores the nature of bacteria, their origin and evolution, bacteria in the environment, and bacteria and disease. In looking at our efforts to manage co-evolving bacteria, he also considers the challenges of resistance to antibiotics. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Author : J.T. Poolman,H.C. Zanen,T.F. Meyer,J.E. Heckels,P. Helena Mäkelä,H. Smith,E.C. Beuvery
Publisher : Springer Science & Business Media
Page : 798 pages
File Size : 50,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789400913837

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Gonococci and Meningococci by J.T. Poolman,H.C. Zanen,T.F. Meyer,J.E. Heckels,P. Helena Mäkelä,H. Smith,E.C. Beuvery Pdf

Epidemiology, Genetics, Immunochemistry and Pathology Proceedings of the Vth Pathogenic Neisseria Conference, Noordwijkerhout, the Netherlands, September 1986

Author : Yi-Wei Tang,Musa Hindiyeh,Dongyou Liu,Andrew Sails,Paul Spearman,Jing-Ren Zhang
Publisher : Academic Press
Page : 3535 pages
File Size : 51,9 Mb
Release : 2023-11-21
Category : Science
ISBN : 9780323899925

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Molecular Medical Microbiology by Yi-Wei Tang,Musa Hindiyeh,Dongyou Liu,Andrew Sails,Paul Spearman,Jing-Ren Zhang Pdf

Molecular Medical Microbiology, Third Edition presents the latest release in what is considered to be the first book to synthesize new developments in both molecular and clinical research. The molecular age has brought about dramatic changes in medical microbiology, along with great leaps in our understanding of the mechanisms of infectious disease. This third edition is completely updated, reviewed and expanded, providing a timely and helpful update for microbiologists, students and clinicians in the era of increasing use of molecular techniques, changing epidemiology and prevalence, and increasing resistance of many pathogenic bacteria. Written by experts in the field, chapters include cutting-edge information and clinical overviews for each major bacterial group, along with the latest updates on vaccine development, molecular technology and diagnostic technology. Completely updated and revised edition of this comprehensive and accessible reference on molecular medical microbiology Includes full color presentations throughout Delves into in-depth discussions on individual pathogenic bacteria in a system-oriented approach Includes a clinical overview for each major bacterial group Presents the latest information on vaccine development, molecular technology and diagnostic technology Provides more than 100 chapters on all major groups of bacteria

Author : Crispian Scully,Jacobo Limeres Posse,Pedro Diz Dios
Publisher : Academic Press
Page : 122 pages
File Size : 43,7 Mb
Release : 2017-07-19
Category : Medical
ISBN : 9780128136829

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Saliva Protection and Transmissible Diseases by Crispian Scully,Jacobo Limeres Posse,Pedro Diz Dios Pdf

Saliva Protection and Transmissible Diseases provides a review of saliva protection, raising debate on micro-organisms potentially transmissible in saliva, and also considering the evidence on diseases that may be transmitted by kissing. Saliva is a complex body fluid essential to health, especially mastication, swallowing and speech, and hyposalivation can lead to dysfunction and even infection. More serious pathogens, such as herpes viruses and papillomaviruses can be conveyed by kissing, as can potentially lethal micro-organisms present in some saliva, such as meningococci, fungal organisms and Ebola viruses. Stipulates the defensive roles of saliva, an important topic not previously reviewed in-depth in literature Provides awareness that saliva also transmits infectious agents that can produce serious or even lethal diseases Gives understanding that kissing may be an at-risk practice

Author : Barbara H. Iglewski
Publisher : Elsevier
Page : 486 pages
File Size : 54,9 Mb
Release : 1990-01-01
Category : Science
ISBN : 9780323148672

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Molecular Basis of Bacterial Pathogenesis by Barbara H. Iglewski Pdf

Molecular Basis of Bacterial Pathogenesis focuses on the molecular mechanism of disease associated with bacterial pathogens. Topics covered include the population genetics of bacterial pathogenesis; environmental modulation of gene expression in gram-negative pathogens; and bacterial invasion and intracellular growth. Bacterial toxins are also discussed. This volume is comprised of 20 chapters and begins with an overview of pathogenesis, paying particular attention to common elements and genetic mechanisms of regulation. The discovery that many bacterial pathogens are clonal, with individual clones often having a greater virulence than others, is then considered. The next section deals with the regulation of synthesis of surface components and their role in colonization of the host and/or evasion of the host immune defense systems; antigenic variation and its role in evasion of the host immune response; and the role of iron acquisition systems in the colonization of the host. Subsequent chapters explore the invasion and intracellular growth of facultative and obligate intracellular parasites. The last section is devoted to studies on the role of bacterial toxic products in pathogenesis. Bacterial lipopolysaccharides (endotoxins) and exotoxins are described. This book should be of interest to molecular biologists, physiologists, clinical specialists, pathologists, and geneticists.

Author : Eduardo A. Groisman
Publisher : Academic Press
Page : 863 pages
File Size : 48,6 Mb
Release : 2001-01-09
Category : Medical
ISBN : 9780080539584

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Principles of Bacterial Pathogenesis by Eduardo A. Groisman Pdf

Principles of Bacterial Pathogenesis presents a molecular perspective on a select group of bacterial pathogens by having the leaders of the field present their perspective in a clear and authoritative manner. Each chapter contains a comprehensive review devoted to a single pathogen. Several chapters include work from authors outside the pathogenesis field, providing general perspectives on the evolution, regulation, and secretion of virulence and determinants. Explains the basic principles of bacterial pathogenesis Covers diverse aspects integrating regulation, cellular microbiology and evolution of microbial disease of humans Discusses current strategies for the identification of virulence determinants and the methods used by microbes to deliver virulence factors Presents authoritative treatises of the major disease microorganisms

Author : Anonim
Publisher : Academic Press
Page : 620 pages
File Size : 55,5 Mb
Release : 1998-07-01
Category : Science
ISBN : 0080860567

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Bacterial Pathogenesis by Anonim Pdf

Established almost 30 years ago, Methods in Microbiology is the most prestigious series devoted to techniques and methodology in the field. Now totally revamped, revitalized, with a new format and expanded scope, Methods in Microbiology will continue to provide you with tried and tested, cutting-edge protocols to directly benefit your research. Focuses on the methods most useful for the microbiologist interested in the way in which bacteria cause disease Includes section devoted to 'Approaches to characterising pathogenic mechanisms' by Stanley Falkow Covers safety aspects, detection, identification and speciation Includes techniques for the study of host interactions and reactions in animals and plants Describes biochemical and molecular genetic approaches Essential methods for gene expression and analysis Covers strategies and problems for disease control

Author : Stephen A. Morse,King K. Holmes,Ronald C. Ballard
Publisher : Elsevier Health Sciences
Page : 389 pages
File Size : 40,6 Mb
Release : 2010-09-17
Category : Medical
ISBN : 9780702047640

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Atlas of Sexually Transmitted Diseases and AIDS E-Book by Stephen A. Morse,King K. Holmes,Ronald C. Ballard Pdf

The Atlas of Sexually Transmitted Diseases and AIDS, 4th Edition, by Drs. Stephen A. Morse, King K. Holmes, Adele A. Moreland, MD, and Ronald C. Ballard, provides you with an exclusive gallery of STD and AIDS images so you can better diagnose and treat these diseases. Approximately 1,100 unique images – most in full color and 30% new to this edition – depict the clinical signs associated with each type of infection. You’ll also find expert guidance on new vaccines, screening techniques, treatment guidelines, and best practices in the field. Get expert advice on the tests available to reach a definitive diagnosis and review therapeutic options, treatment guidelines, prevention strategies, and management of complications. Access appendices on the selection and evaluation of diagnostic tests, quality control, and test technologies. Effectively diagnose all types of STDs and HIV/AIDS with approximately 1,100 images—most in full color and more than 30% new to this edition―that depict the epidemiology as well as the clinical manifestations of these diseases. Effectively utilize new vaccines for HPV and Hepatitis B, new screening tests for Chlamydia, new drugs under development, new treatment guidelines and best practices in HIV screening, and much more.

Author : World Health Organization
Publisher : World Health Organization
Page : 216 pages
File Size : 48,8 Mb
Release : 2021-07-15
Category : Medical
ISBN : 9789240024168

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Guidelines for the management of symptomatic sexually transmitted infections by World Health Organization Pdf

The WHO global health sector strategy on sexually transmitted infections, 2016–2021, endorsed by the World Health Assembly in 2016, aims to eliminate STIs as a public health threat by 2030. In 2019, WHO published estimates of new cases of chlamydia, gonorrhoea, syphilis and trichomoniasis. Recent changes in the epidemiology of STIs and progress in prevention, diagnosis and treatment of STIs and HIV have necessitated changes in approaches to STI prevention and management. To address these STIs, the most widely used approach in clinical settings is the syndromic management of STIs. In most resource-limited settings, the syndromic management flow charts are still the standard of care where laboratory diagnosis is not available or is hard to access. The objectives of these guidelines are to provide updated, evidence-informed clinical and practical recommendations on the case management of people with symptoms of STIs; and to support countries in updating their national guidelines for the case management of people with symptoms of STIs. These guidelines include the management of symptomatic infections related to urethral discharge syndrome, including persistent urethral discharge syndrome; vaginal discharge syndrome, including persistent vaginal discharge; anorectal infection; genital ulcer disease syndrome; and lower abdominal pain syndrome. These guidelines are intended for programme managers for STI prevention and control at the national level and the health-care providers at the frontline – primary, secondary and tertiary health care.

Author : Sunit Kumar Singh
Publisher : John Wiley & Sons
Page : 1072 pages
File Size : 53,7 Mb
Release : 2015-11-09
Category : Science
ISBN : 9781118644645

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Human Emerging and Re-emerging Infections by Sunit Kumar Singh Pdf

Emerging and re-emerging pathogens pose several challenges to diagnosis, treatment, and public health surveillance, primarily because pathogen identification is a difficult and time-consuming process due to the “novel” nature of the agent. Proper identification requires a wide array of techniques, but the significance of these diagnostics is anticipated to increase with advances in newer molecular and nanobiotechnological interventions and health information technology. Human Emerging and Re-emerging Infections covers the epidemiology, pathogenesis, diagnostics, clinical features, and public health risks posed by new viral and microbial infections. The book includes detailed coverage on the molecular mechanisms of pathogenesis, development of various diagnostic tools, diagnostic assays and their limitations, key research priorities, and new technologies in infection diagnostics. Volume 1 addresses viral and parasitic infections, while volume 2 delves into bacterial and mycotic infections. Human Emerging and Re-emerging Infections is an invaluable resource for researchers in parasitologists, microbiology, Immunology, neurology and virology, as well as clinicians and students interested in understanding the current knowledge and future directions of infectious diseases.