Molecular Pathology Of Liver Diseases

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Molecular Pathology of Liver Diseases

Author : Satdarshan P. S. Monga
Publisher : Springer Science & Business Media
Page : 919 pages
File Size : 41,5 Mb
Release : 2010-12-14
Category : Medical
ISBN : 1441971076

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Molecular Pathology of Liver Diseases by Satdarshan P. S. Monga Pdf

Cellular and Molecular Pathology of the Liver is extensive, complex and ranges from the understanding the basic molecular mechanisms that dictate everything from liver homeostasis to liver disease. Molecular Pathology of the liver is complicated due to some of the important functions inherent and unique to the Liver, including its innate ability to regenerate and the multitude of functions it plays for the wellbeing of an organism. With all this in mind, Molecular Pathology of Liver Diseases is organized in different sections, which will coherently and cohesively present the molecular basis of hepatic physiology and pathology. The first two sections are key to understanding the liver anatomy and physiology at a cellular level and go on to define the molecular mechanics in various liver cell types. These sections also cover the existing paradigms in liver development, regeneration and growth. The next section is key to understanding the Molecular Pathology unique to liver diseases and associated phenotypes. The final sections are geared towards the existing knowledge of the molecular basis of many common and uncommon liver diseases in both neoplastic and non-neoplastic areas including pathologies associated with intra-hepatic and extra-hepatic biliary tree. Thus, this textbook is a one-stop reference for comprehending the molecular mechanisms of hepatic pathobiology. It is clearly unique in its format, readability and information and thus will be an asset to many in the field of Pathology and other disciplines.

Molecular Pathology of Liver Diseases

Author : Satdarshan P. S. Monga
Publisher : Springer
Page : 931 pages
File Size : 53,5 Mb
Release : 2016-08-23
Category : Medical
ISBN : 1489977821

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Molecular Pathology of Liver Diseases by Satdarshan P. S. Monga Pdf

Cellular and Molecular Pathology of the Liver is extensive, complex and ranges from the understanding the basic molecular mechanisms that dictate everything from liver homeostasis to liver disease. Molecular Pathology of the liver is complicated due to some of the important functions inherent and unique to the Liver, including its innate ability to regenerate and the multitude of functions it plays for the wellbeing of an organism. With all this in mind, Molecular Pathology of Liver Diseases is organized in different sections, which will coherently and cohesively present the molecular basis of hepatic physiology and pathology. The first two sections are key to understanding the liver anatomy and physiology at a cellular level and go on to define the molecular mechanics in various liver cell types. These sections also cover the existing paradigms in liver development, regeneration and growth. The next section is key to understanding the Molecular Pathology unique to liver diseases and associated phenotypes. The final sections are geared towards the existing knowledge of the molecular basis of many common and uncommon liver diseases in both neoplastic and non-neoplastic areas including pathologies associated with intra-hepatic and extra-hepatic biliary tree. Thus, this textbook is a one-stop reference for comprehending the molecular mechanisms of hepatic pathobiology. It is clearly unique in its format, readability and information and thus will be an asset to many in the field of Pathology and other disciplines.

Precision Molecular Pathology of Liver Cancer

Author : Chen Liu
Publisher : Springer
Page : 271 pages
File Size : 53,8 Mb
Release : 2018-01-09
Category : Medical
ISBN : 9783319680828

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Precision Molecular Pathology of Liver Cancer by Chen Liu Pdf

This volume provides the most updated knowledge on the advancement of molecular pathogenesis, molecular diagnosis, and therapy development for hepatocellular carcinoma (HCC). Topics covered include the etiology and pathogenesis of HCC, recent advances in HCC genomics, biomarker discovery and validation in HCC diagnosis, the role of liver biopsy in HCC early diagnosis, and the future prospects of surgical approaches and targeted therapy for HCC. In addition to reviewing the current available knowledge, the book also discusses the future development of a precision and personalized medicine approach for HCC. Written by experts in the field, Precision Molecular Pathology of Liver Cancer is a concise yet comprehensive resource for practitioners who treat patients with hepatocellular carcinoma.

Biopsy Interpretation of the Liver

Author : Stephen A. Geller,Lydia M. Petrovic
Publisher : Lippincott Williams & Wilkins
Page : 454 pages
File Size : 41,9 Mb
Release : 2012-03-28
Category : Medical
ISBN : 9781451148565

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Biopsy Interpretation of the Liver by Stephen A. Geller,Lydia M. Petrovic Pdf

Biopsy Interpretation of the Liver, Second Edition offers pathologists clear, practical guidelines for recognizing and diagnosing the full spectrum of liver disorders. Coverage begins with the basics—including technical considerations, liver anatomy, and examination methods—and progresses to specific disorders, with particular emphasis on histopathology. This completely updated Second Edition includes new material on transplantation pathology and new chapters on immunopathology and molecular pathology of liver diseases. A companion Website will provide the fully searchable text, over 700 additional full-color images of common and rare entities, and a test bank that is ideal for board exam preparation.

Acute and Chronic Liver Diseases

Author : R. Schmid
Publisher : Springer
Page : 424 pages
File Size : 49,7 Mb
Release : 1996-06-30
Category : Medical
ISBN : UOM:39015037805309

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Acute and Chronic Liver Diseases by R. Schmid Pdf

The advent of molecular biology and recombinant DNA technology has profoundly changed contemporary medicine. These new scientific tools have made it possible to identify and understand pathological mechanisms at cellular, subcellular and molecular levels which has added previously unimaginable novel dimensions to the diagnosis, therapy and prevention of a rapidly increasing number of diseases of the liver and biliary system. The title of this book - Acute and Chronic Liver Diseases: Molecular Biology and Clinics - expresses this epochal progress in hepatology. A series of acute or chronic diseases of the liver has been chosen whose modern clinical management most eloquently reflects the impact of the new scientific insight gained from molecular biology. The book, the proceedings of the 87th Falk Symposium (X International Congress of Liver Diseases: Part II of the Basel Liver Week 1995) held in Basel, Switzerland, October 19-21, 1995, first presents an overview of the molecular pathology of the chosen disease, followed by discussions of the clinical inference which this new scientific information entails for diagnosis, management and therapy. This approach is expected to ease the readers' endeavour to connect basic to clinical science and to facilitate appreciation of the enormous progress but also the inherent limitations and arising questions which modern molecular biology has brought to clinical medicine.

Molecular Pathology

Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Academic Press
Page : 802 pages
File Size : 43,9 Mb
Release : 2017-11-09
Category : Medical
ISBN : 9780128027875

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Molecular Pathology by William B. Coleman,Gregory J. Tsongalis Pdf

As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase

Molecular Pathology

Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Academic Press
Page : 659 pages
File Size : 52,7 Mb
Release : 2009-03-10
Category : Medical
ISBN : 9780123859129

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Molecular Pathology by William B. Coleman,Gregory J. Tsongalis Pdf

Molecular Pathology: The Molecular Basis of Human Disease provides a current and comprehensive view of the molecular basis and mechanisms of human disease. Combining accepted principles with broader theoretical concepts and with contributions from a group of experts, the book looks into disease processes in the context of traditional pathology and their implications for translational molecular medicine. It also discusses concepts in molecular biology and genetics, recent scientific and technological advances in modern pathology, the concept of ""molecular pathogenesis"" of disease, and how disease evolves from normal cells and tissues due to perturbations in molecular pathways. The book describes the integration of molecular and cellular pathogenesis using a bioinformatics approach and a systems biology approach to disease pathogenesis. It also discusses current and future strategies in molecular diagnosis of human disease, and the impact of molecular diagnosis on treatment decisions and the practice of personalized medicine. This book is a valuable resource for students, biomedical researchers, practicing physician-scientists who undertake disease-related basic science and translational research, and pathology residents and other postdoctoral fellows. * Exam Master® web site will host "Self-assessment" questions that students can use to study for the molecular section of the board exam * Companion Web Site – will host a complete set of PowerPoint slides: to include images from the book and additional images for teaching; course materials; lecture materials * Teaches from the perspective of “integrative systems biology, which encompasses the intersection of all molecular aspects of biology, as applied to understanding human disease * Outlines the principles and practice of molecular pathology * Explains the practice of “molecular medicine and the translational aspects of molecular pathology

Surgical Pathology of the Liver

Author : Michael Torbenson,Roger Moreira,Lizhi Zhang
Publisher : Lippincott Williams & Wilkins
Page : 664 pages
File Size : 43,9 Mb
Release : 2017-11-08
Category : Medical
ISBN : 9781496397744

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Surgical Pathology of the Liver by Michael Torbenson,Roger Moreira,Lizhi Zhang Pdf

Written by surgical pathologists for surgical pathologists, Surgical Pathology of the Liver focuses on sharpening your skills and knowledge in diagnostic histopathology, including laboratory and clinical findings that are directly useful when evaluating liver histology for clinical care. It offers comprehensive, superbly illustrated coverage of general liver pathology, as well as several chapters on topics that are not often included in liver pathology textbooks. Abundant high-quality illustrations have been carefully chosen to support and extend the information given in the text.

Liver Pathology

Author : Linda D. Ferrell, MD,Sanjay Kakar, MD
Publisher : Demos Medical Publishing
Page : 561 pages
File Size : 44,7 Mb
Release : 2011-03-28
Category : Medical
ISBN : 9781933864938

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Liver Pathology by Linda D. Ferrell, MD,Sanjay Kakar, MD Pdf

This unique book provides detailed insight into a wealth of expert experience in liver pathology, with an in-depth review of the expertÌs analysis and diagnostic process supported by high-quality color photomicrographs and discussion of the diagnostic principles involved in evaluating these lesions. The diagnostic problems and cases selected show the wide range of specimens seen in liver pathology and address the difficult issues in diagnosis encountered in these lesions. Chapters and cases are authored by many of the leading experts and educators in liver pathology today. Liver Pathology will be essential reading for every pathologist who evaluates liver pathology specimens. In addition it will be a valuable resource for pathology residents and fellows. All Consultant Pathology Titles Provide: Actual consultation cases and expert analysis Expert analysis provides a detailed discussion of the reasoning behind the diagnosis of each case Comprehensive coverage of challenging diagnoses The cases are richly illustrated with high-quality photomicrographs

The Liver

Author : Irwin M. Arias,Allan W. Wolkoff,James L. Boyer,David A. Shafritz,Nelson Fausto,Harvey J. Alter,David E. Cohen
Publisher : John Wiley & Sons
Page : 2022 pages
File Size : 53,5 Mb
Release : 2011-08-24
Category : Medical
ISBN : 9781119964223

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The Liver by Irwin M. Arias,Allan W. Wolkoff,James L. Boyer,David A. Shafritz,Nelson Fausto,Harvey J. Alter,David E. Cohen Pdf

In its Fifth Edition, this classic book retains its traditional strength of relating molecular physiology to understanding disease pathology and treatment as it explores the current state and future direction of hepatology. Painstakingly revised, this edition includes 60 new chapters. As in previous editions, a section called Horizons summarizes advances of extraordinary nature in areas expected to have a substantial impact on hepatology. The Fifth Edition’s Horizons section includes emerging topics such as tissue engineering of the liver, liver-directed gene therapy, decoding the liver cancer genome, and imaging cellular proteins and structure. To preserve essential background information which has not changed while making room for the panoply of major new contributions to understanding of liver disease, 14 chapters from the previous edition are freely available online at gastrohep.com. To view these chapters visit - http://www.gastrohep.com/theliver/

Diagnostic Pathology: Hepatobiliary and Pancreas E-Book

Author : Laura Webb Lamps,Maria Westerhoff,Sanjay Kakar
Publisher : Elsevier Health Sciences
Page : 500 pages
File Size : 44,8 Mb
Release : 2021-11-16
Category : Medical
ISBN : 9780323776219

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Diagnostic Pathology: Hepatobiliary and Pancreas E-Book by Laura Webb Lamps,Maria Westerhoff,Sanjay Kakar Pdf

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of neoplastic and nonneoplastic diseases of the digestive tract and accessory organs such as the pancreas and liver, it incorporates the most recent clinical, pathological, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, Diagnostic Pathology: Hepatobiliary and Pancreas is a one-stop reference for accurate, complete pathology reports, ideal as a day-to-day reference or as a reliable training resource. Analyzes hundreds of diagnoses, each of which include critical diagnostic information such as definitions, epidemiology, clinical presentation, macro- and microscopic features, differential diagnoses, and pathologic interpretation pearls. Features thorough updates throughout, including novel immunohistochemical markers and other ancillary techniques (such as BAP1, INSM1, Rb, albumin in situ hybridization) that play an increasingly critical role in improving diagnoses Addresses recent advances in molecular pathology—new diagnostic, immunohistochemical, molecular, and genetic techniques used for diagnosis, as well as new details about the genesis and activity of tumors in the liver, pancreas, and biliary systems Includes details from the 2019 WHO Classification of Tumors of the Digestive System regarding important changes to diagnostic techniques, identification of new variants of cancers, and immunohistochemical markers and ancillary techniques that improve diagnosis and treatment options Reflects recent WHO updates and updates from the AJCC’s 8th Edition Cancer Staging Manual such as new terminology, new grading of neuroendocrine tumors and neuroendocrine carcinomas, and characteristic molecular alterations in hepatocellular adenoma, cholangiocarcinoma, and other tumors Uses a templated page layout, bulleted text, and a generous number of high-quality images to help practicing and in-training pathologists reach a confident diagnosis

Alcoholic Liver Diseases: New Insights for the Healthcare Professional: 2012 Edition

Author : Anonim
Publisher : ScholarlyEditions
Page : 26 pages
File Size : 55,9 Mb
Release : 2012-12-10
Category : Medical
ISBN : 9781464981920

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Alcoholic Liver Diseases: New Insights for the Healthcare Professional: 2012 Edition by Anonim Pdf

Alcoholic Liver Diseases: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Alcoholic Liver Diseases in a compact format. The editors have built Alcoholic Liver Diseases: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Alcoholic Liver Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Alcoholic Liver Diseases: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Cellular and Molecular Mechanisms Underlying the Pathogenesis of Hepatic Fibrosis

Author : Ralf Weiskirchen
Publisher : MDPI
Page : 276 pages
File Size : 55,7 Mb
Release : 2020-12-29
Category : Medical
ISBN : 9783039361885

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Cellular and Molecular Mechanisms Underlying the Pathogenesis of Hepatic Fibrosis by Ralf Weiskirchen Pdf

Worldwide, liver fibrosis is a major cause of morbidity and mortality and is associated with a high medical and economic burden. It is the common consequence of chronic liver injury due to various etiologies. During fibrogenesis, there is a progressive substitution of the liver parenchyma by scar tissue. Recent advances in the understanding of the history of liver fibrosis have shown that the pathogenesis is driven by different cell types and a large variety of soluble mediators. At present, scientists working in this field aim to increase basic knowledge, improve diagnostics, and try to translate experimental findings into new treatment modalities. This book includes 12 selected contributions from the Special Issue “Cellular and Molecular Mechanisms Underlying the Pathogenesis of Hepatic Fibrosis” that was published in Cells. These articles summarize current perspectives and findings in hepatic fibrosis research showing how scientists try to use basic scientific research to create new therapies and diagnostics.

Molecular Pathology

Author : Antoni Horst
Publisher : CRC Press
Page : 452 pages
File Size : 49,5 Mb
Release : 2018-05-04
Category : Science
ISBN : 9781351091671

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Molecular Pathology by Antoni Horst Pdf

This book provides modern views of developments in medical sciences based on advances in molecular pathology. Topics discussed include the molecule; the genome of eukaryotes and its function; gene regulation; the proteins; molecular aspects of inflammation, immunology, and carcinogenesis; molecular biology of the nervous system; molecular defects in the endocrine system; molecular diseases of the blood and blood-forming tissues; and diagnosis of molecular diseases. Four tables and 75 figures illustrate the concepts and provide a quick means to reference important data. Immunologists, pathologists, geneticists, and all other researchers in the biological and medical sciences will find a wealth of information in this ground-breaking new book.

Essential Concepts in Molecular Pathology

Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Academic Press
Page : 634 pages
File Size : 41,7 Mb
Release : 2019-11-23
Category : Medical
ISBN : 9780128132586

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Essential Concepts in Molecular Pathology by William B. Coleman,Gregory J. Tsongalis Pdf

Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today’s advances in pathology and medicine. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology