Multiscale Fabrication Of Functional Materials For Regenerative Medicine

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Multiscale Fabrication of Functional Materials for Regenerative Medicine

Author : Michele Bianchi
Publisher : Springer Science & Business Media
Page : 92 pages
File Size : 44,6 Mb
Release : 2011-08-31
Category : Technology & Engineering
ISBN : 364222881X

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Multiscale Fabrication of Functional Materials for Regenerative Medicine by Michele Bianchi Pdf

Regenerative medicine demands new concepts and fabrication tools to improve our common knowledge about cell-cell and cell-environment interactions. In this work, Michele Bianchi shows that different kinds of signals, such as chemical, topographical, and electrical signals, can be arranged in a highly-controlled way. Furthermore, Michele uses scale lengths ranging from several micrometers to a few nanometers, through the employment of unconventional fabrication techniques. For each signal, Michele chose properly designed materials and fabrication methods. The external signals are capable of controlling cell adhesion and growth, opening the way for a systematic investigation of the environmental features affecting cell behaviour.

Functional Bio-based Materials for Regenerative Medicine From Bench to Bedside (Part 2)

Author : Mohd Fauzi Mh Busra, Daniel Law Jia Xian, Yogeswaran Lokanathan, Ruszymah Haji Idrus
Publisher : Bentham Science Publishers
Page : 309 pages
File Size : 41,5 Mb
Release : 2024-02-02
Category : Medical
ISBN : 9789815179347

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Functional Bio-based Materials for Regenerative Medicine From Bench to Bedside (Part 2) by Mohd Fauzi Mh Busra, Daniel Law Jia Xian, Yogeswaran Lokanathan, Ruszymah Haji Idrus Pdf

Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside explores the use of bio-based materials for the regeneration of tissues and organs. The book presents an edited collection of 28 topics in 2 parts focused on the translation of these materials from laboratory research (the bench) to practical applications in clinical settings (the bedside). Chapter authors highlight the significance of bio-based materials, such as hydrogels, scaffolds, and nanoparticles, in promoting tissue regeneration and wound healing. Topics in the book include: - the properties of bio-based materials, including biocompatibility, biodegradability, and the ability to mimic the native extracellular matrix. - fabrication techniques and approaches for functional bio-based material design with desired characteristics like mechanical strength and porosity to promote cellular attachment, proliferation, and differentiation - the incorporation of bioactive molecules, such as growth factors, into bio-based materials to enhance their regenerative potential. - strategies for the controlled release of molecules to create a favorable microenvironment for tissue regeneration. - the challenges and considerations involved in scaling up the production of bio-based materials, ensuring their safety and efficacy, and obtaining regulatory approval for clinical use Part 2 covers advanced materials and techniques used in tissue engineering. Topics focus on advanced composite materials for 3D scaffolds and the repair of tissues in different organs such as the heart, cornea, bone and ligaments. Materials highlighted in this part include polyamide composites, electrospun nanofibers, and different bio-based hydrogels. Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside is a valuable reference for researchers in biomedical engineering, cell biology, and regenerative medicine who want to update their knowledge on current developments in the synthesis and application of functional biomaterials.

Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside (Part 1)

Author : Mohd Fauzi Mh Busra,Daniel Law Jia Xian,Yogeswaran Lokanathan,Ruszymah Haji Idrus
Publisher : Bentham Science Publishers
Page : 311 pages
File Size : 45,8 Mb
Release : 2023-07-25
Category : Medical
ISBN : 9789815123111

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Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside (Part 1) by Mohd Fauzi Mh Busra,Daniel Law Jia Xian,Yogeswaran Lokanathan,Ruszymah Haji Idrus Pdf

Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside explores the use of bio-based materials for the regeneration of tissues and organs. The book presents an edited collection of 28 topics in 2 parts focused on the translation of these materials from laboratory research (the bench) to practical applications in clinical settings (the bedside). Chapter authors highlight the significance of bio-based materials, such as hydrogels, scaffolds, and nanoparticles, in promoting tissue regeneration and wound healing. Topics included in the book include: - the properties of bio-based materials, including biocompatibility, biodegradability, and the ability to mimic the native extracellular matrix. - fabrication techniques and approaches for functional bio-based material design with desired characteristics like mechanical strength and porosity to promote cellular attachment, proliferation, and differentiation - the incorporation of bioactive molecules, such as growth factors, into bio-based materials to enhance their regenerative potential. - strategies for the controlled release of molecules to create a favorable microenvironment for tissue regeneration. - the challenges and considerations involved in scaling up the production of bio-based materials, ensuring their safety and efficacy, and obtaining regulatory approval for clinical use Part 1 covers techniques for tissue engineering, wound healing and skin engineering. It also presents reviews on techniques such as acellular synthesis and 3D bioprinting. Materials highlighted in this part include chitosan-based nanoparticles, nanocollagen-based materials and plant based composites. Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside is a valuable reference for researchers in biomedical engineering, cell biology, and regenerative medicine who want to update their knowledge on current developments in the synthesis and application of functional biomaterials.

Functional Nanomaterials for Regenerative Tissue Medicines

Author : Mariappan Rajan
Publisher : CRC Press
Page : 429 pages
File Size : 53,8 Mb
Release : 2021-12-08
Category : Technology & Engineering
ISBN : 9781000486940

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Functional Nanomaterials for Regenerative Tissue Medicines by Mariappan Rajan Pdf

This book covers nanomaterials in tissue engineering for regenerative therapies of heart, skin, eye, skeletal muscle, and the nervous system. The book emphasizes fundamental design concepts and emerging forms of nanomaterials in soft- and hard-tissue engineering. FEATURES Fills a gap in the literature related to the application of nanomaterials in hard- and soft-tissue regeneration, repair, and restructure Discusses a variety of applications, including cardiac, kidney, liver, bone, wound healing, artificial organs, and dental Presents advantages and limitations of various nanomaterials alongside future challenges Functional Nanomaterials for Regenerative Tissue Medicines is essential for academics and industry professionals working in tissue engineering, biomedicine, biopharmaceuticals, and nanotechnology. It is primarily intended for materials researchers (to develop the platforms related to tissue regeneration) as well as clinicians (to learn and apply nanomaterials in their practice) and industrial scientists (to develop commercial blood substitute products).

Multiscale Cell-Biomaterials Interplay in Musculoskeletal Tissue Engineering and Regenerative Medicine

Author : J. Miguel Oliveira,Rui L. Reis,Sandra Pina
Publisher : Elsevier
Page : 556 pages
File Size : 54,5 Mb
Release : 2023-11-28
Category : Science
ISBN : 9780323972628

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Multiscale Cell-Biomaterials Interplay in Musculoskeletal Tissue Engineering and Regenerative Medicine by J. Miguel Oliveira,Rui L. Reis,Sandra Pina Pdf

Multiscale Cell-Biomaterials Interplay in Musculoskeletal Tissue Engineering and Regenerative Medicine addresses the key concepts involved in the interactions between cells and biomaterials in the musculoskeletal tissue engineering and regenerative medicine field. The updated developments and challenges of the mechanisms/mechanobiology and structure-function properties of those interactions, as well as emerging technologies underlying tissue-engineered scaffolding, are carefully discussed. Lastly, cell engineering and cell-based therapies, growth factors/drugs properties, vascularization, immunomodulation are also outlined. Given the large number of musculoskeletal disorders and related injuries that can affect muscles, bones and joints and lead to severe complications of the neuromuscular system, it is imperative to develop new treatment strategies to delay or repair associated diseases and to promote optimal long-term health. Presents the fundamentals of the complex interplay of cells with biomaterials in musculoskeletal tissue engineering Includes coverage of stem cells and cell-based therapies, in vitro and in vivo models, nanotechnology, bioprinting, computational modeling, regulatory and clinical translation, and much more Written by global leaders in the field

Tissue Engineering and Regenerative Nanomedicine

Author : J. Miguel Oliveira,Oliveira Rui L. Reis
Publisher : MDPI
Page : 126 pages
File Size : 48,7 Mb
Release : 2019-11-11
Category : Technology & Engineering
ISBN : 9783039216567

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Tissue Engineering and Regenerative Nanomedicine by J. Miguel Oliveira,Oliveira Rui L. Reis Pdf

[This book focus on the most recent advances related to the design and processing methods of different nanobiomaterials, films, and fibers; surface functionalization strategies, including biological performance assessment and cytocompatibility; and their applications in tissue engineering strategies.]

Regenerative Engineering

Author : Yusuf Khan,Cato T. Laurencin
Publisher : CRC Press
Page : 322 pages
File Size : 46,6 Mb
Release : 2018-04-19
Category : Medical
ISBN : 9781351647397

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Regenerative Engineering by Yusuf Khan,Cato T. Laurencin Pdf

This book focuses on advances made in both materials science and scaffold development techniques, paying close attention to the latest and state-of-the-art research. Chapters delve into a sweeping variety of specific materials categories, from composite materials to bioactive ceramics, exploring how these materials are specifically designed for regenerative engineering applications. Also included are unique chapters on biologically-derived scaffolding, along with 3D printing technology for regenerative engineering. Features: Covers the latest developments in advanced materials for regenerative engineering and medicine. Each chapter is written by world class researchers in various aspects of this medical technology. Provides unique coverage of biologically derived scaffolding. Includes separate chapter on how 3D printing technology is related to regenerative engineering. Includes extensive references at the end of each chapter to enhance further study.

Engineering Materials for Stem Cell Regeneration

Author : Faheem A. Sheikh
Publisher : Springer Nature
Page : 709 pages
File Size : 43,5 Mb
Release : 2021-10-23
Category : Science
ISBN : 9789811644207

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Engineering Materials for Stem Cell Regeneration by Faheem A. Sheikh Pdf

This book reviews the interface of stem cell biology and biomaterials for regenerative medicine. It presents the applications of biomaterials to support stem cell growth and regeneration. The book discusses the stem cell interactions’ with nanofiber, gradient biomaterial, polymer- and ceramic biomaterials, integrating top-down and bottom-up approaches, adhesive properties of stem cells on materials, cell-laden hydrogels, micro-and nanospheres, de-cellularization techniques, and use of porous scaffolds. Further, this book provides a basic introduction to the fabrication techniques for creating various biomaterials that can be used for stem cell differentiation. It also elucidates the properties of stem cells, their characteristic features, tissue culture technology, properties of pluripotency, osteogenesis, and biomaterial interaction with de-cellularized organs, cell lineage in vivo and in vitro, gene expression, embryonic development, and cell differentiation. Further, the book reviews the latest applications of bio-instructive scaffold for supporting stem cell differentiation and tissue regeneration. The book also presents stem cell for dental, alveolar bone and cardiac regeneration. Lastly, it introduces engineered stem cells for delivering small molecule therapeutics and their potential biomedical applications.

Biomaterials in Tissue Engineering and Regenerative Medicine

Author : Birru Bhaskar,Parcha Sreenivasa Rao,Naresh Kasoju,Vasagiri Nagarjuna,Rama Raju Baadhe
Publisher : Springer Nature
Page : 587 pages
File Size : 48,6 Mb
Release : 2021-04-29
Category : Medical
ISBN : 9789811600029

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Biomaterials in Tissue Engineering and Regenerative Medicine by Birru Bhaskar,Parcha Sreenivasa Rao,Naresh Kasoju,Vasagiri Nagarjuna,Rama Raju Baadhe Pdf

This book comprehensively explores the basic concepts and applications of biomaterials in tissue engineering and regenerative medicine. The book is divided into four sections; the first section deals with the basic concepts and different types of biomaterials used in tissue engineering. The second section discusses the functional requirements and types of materials that are used in developing state-of-the-art of scaffolds for tissue engineering applications. The third section presents the applications of biomaterials for hard and soft tissue engineering, as well as for specialized tissue engineering. The last section addresses the future prospects of nanobiomaterials, intelligent biomaterials, and 3D bioprinting biomaterials in tissue engineering and regenerative medicine. It also discusses various in vitro disease models for tissue bioengineering and regenerative medicine. As such, it offers a valuable resource for students, researchers, scientists, entrepreneurs, and medical/healthcare professionals.

Vat Photopolymerization Additive Manufacturing

Author : Xiaolong Wang
Publisher : Elsevier
Page : 520 pages
File Size : 55,8 Mb
Release : 2024-04-26
Category : Technology & Engineering
ISBN : 9780443154881

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Vat Photopolymerization Additive Manufacturing by Xiaolong Wang Pdf

Vat Photopolymerization 3D Printing: Processes, Materials, and Applications focuses on the cutting-edge vat polymerization additive manufacturing technology, as well as its associated materials and potential applications. The book is divided into four parts, with the first providing some foundational concepts about the technology as well as providing background on the different vat photopolymerization techniques, such as grayscale, volumetric, multiwavelength, two-photon and more. The basic chemistry involved in the vat photopolymerization process is covered here as well. Section 2 discusses vat photopolymerization 3D printing of functional materials, including plastics, hydrogels, stimuli-responsive polymers, ceramics, and more. Section 3 covers various applications of the materials created, and the book concludes with a section looking at the future direction of vat photopolymerization 3D printing. Provides a detailed introduction to the technology, materials, and applications of vat photopolymerization additive manufacturing (AM) Discusses the basic chemistry in the vat photopolymerization process, including chemical reactions, ink components, functional additives, inhibitors, and more Covers techniques for creating plastics, hydrogels, shape memory polymers, ceramics, and more Details applications in bioengineering, engineering, metamaterials, and bio-inspired structures and functions

Electrospun Polymeric Nanofibers

Author : R. Jayakumar
Publisher : Springer Nature
Page : 468 pages
File Size : 46,9 Mb
Release : 2023-04-27
Category : Technology & Engineering
ISBN : 9783031314032

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Electrospun Polymeric Nanofibers by R. Jayakumar Pdf

This volume deals with the various fabrication techniques, surface functionalization and biomedical applications of polymeric fibers possessing different scale and structure. It provides an overview of fabrication techniques such as Co-axial, Centrifugal, Melt and Yarning to procure multiscale, tubular and layered fibrous scaffold employed for biomedical applications. The chapters in this volume discusse the surface/chemical functionalization of fibers which enhance the biological properties of the fibrous scaffolds as well as the development of hybrid, layered and external stimuli-responsive fibrous scaffolds that hold potential application in biosensor and other biomedical fields. In addition, recent advances and applications of polymeric multiscale fibers in tissue engineering, regenerative medicine and drug delivery are presented. The potential use of fibrous scaffolds in bone, neural, tendon/ligament and cardiac tissue engineering, nanofibers as an antimicrobial wound dressing, employed in cancer theragnostics and in the treatment of skin/periodontal infections are discussed. The volume provides expert knowledge on the fabrication techniques, development of different scale and hybrid structure fibers, surface functionalization, layered and external stimuli responsive fibrous scaffolds. It will be beneficial to material/biomaterials scientists, bioengineering and biotechnologists by providing a better understanding on the subject of the innovative applications of fibrous scaffolds in drug delivery, tissue engineering, wound dressings and regenerative medicine.

Hydrogels for Tissue Engineering and Regenerative Medicine

Author : J. Miguel Oliveira,Joana Silva-Correia,Rui L. Reis
Publisher : Academic Press
Page : 851 pages
File Size : 55,7 Mb
Release : 2023-09-29
Category : Science
ISBN : 9780128242254

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Hydrogels for Tissue Engineering and Regenerative Medicine by J. Miguel Oliveira,Joana Silva-Correia,Rui L. Reis Pdf

Hydrogels for Tissue Engineering and Regenerative Medicine: From Fundaments to Applications provides the reader with a comprehensive, concise and thoroughly up-to-date resource on the different types of hydrogels in tissue engineering and regenerative medicine. The book is divided into three main sections that describe biological activities and the structural and physicochemical properties of hydrogels, along with a wide range of applications, including their combination with emerging technologies. Written by a diverse range of international academics for professionals, researchers, undergraduate and graduate students, this groundbreaking publication fills a gap in literature needed in the tissue engineering and regenerative medicine field. Reviews the fundamentals and recent advances of hydrogels in tissue engineering and regenerative medicine applications Presents state-of-the-art methodologies for the synthesis and processing of different types of hydrogels Includes contributions by leading experts in engineering, the life sciences, microbiology and clinical medicine

Nanoengineered Biomaterials for Regenerative Medicine

Author : Masoud Mozafari,Jayakumar Rajadas,David Kaplan
Publisher : Elsevier
Page : 516 pages
File Size : 40,6 Mb
Release : 2018-09-17
Category : Science
ISBN : 9780128133569

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Nanoengineered Biomaterials for Regenerative Medicine by Masoud Mozafari,Jayakumar Rajadas,David Kaplan Pdf

Nanoengineered Biomaterials for Regenerative Medicine showcases the advances that have taken place in recent years as an increasing number of nanoengineered biomaterials have been targeted to various organ tissues. The book systematically explores how nanoengineered biomaterials are used in different aspects of regenerative medicine, including bone regeneration, brain tissue reconstruction and kidney repair. It is a valuable reference resource for scientists working in biomaterials science who want to learn more about how nanoengineered materials are practically applied in regenerative medicine. Nanoengineered biomaterials have gained particular focus due to their many advantages over conventional techniques for tissue repair. As a wide range of biomaterials and nanotechnology techniques have been examined for the regeneration of tissues, this book highlights the discussions and advancements made. Provides a digestible reference source for surgeons and physicians who want to learn more on nanoengineered biomaterials and their use in effective medical treatments Offers systematic coverage on how nanoengineered biomaterials are used for different types of medicine Assesses the benefits and drawbacks of the use of bioengineered nanomaterials in different areas of regenerative medicine

Polymeric Biomaterials for Tissue Regeneration

Author : Changyou Gao
Publisher : Springer
Page : 381 pages
File Size : 45,8 Mb
Release : 2016-10-08
Category : Medical
ISBN : 9789811022937

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Polymeric Biomaterials for Tissue Regeneration by Changyou Gao Pdf

This book reviews state-of-the-art of polymeric biomaterials for regenerative medicine, and highlights advances in both basic science and clinical practice. It summarizes the latest techniques in polymeric scaffold fabrication, delivery carriers, physicochemical property modulation, as well as their influence on adhesion and the performance of biomolecules, cells and tissues. It also describes methods for creating biofunctional surfaces/interfaces and subsequently modulating the host response to implantable materials. Lastly, it discusses the applications of biomaterials and constructs in soft-tissue regenerative medicine. It is a valuable resource for materials scientists and engineers wishing to identify research priorities to fulfill clinical needs and provides physicians with insights into emerging novel biomaterials. This integrated approach also offers engineering students a sense of the relevance of materials science in the development of novel therapeutic strategies.

Novel Biomaterials for Regenerative Medicine

Author : Heung Jae Chun,Kwideok Park,Chun-Ho Kim,Gilson Khang
Publisher : Springer
Page : 537 pages
File Size : 54,8 Mb
Release : 2018-10-24
Category : Medical
ISBN : 9789811309472

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Novel Biomaterials for Regenerative Medicine by Heung Jae Chun,Kwideok Park,Chun-Ho Kim,Gilson Khang Pdf

This book explores in depth a wide range of new biomaterials that hold great promise for applications in regenerative medicine. The opening two sections are devoted to biomaterials designed to direct stem cell fate and regulate signaling pathways. Diverse novel functional biomaterials, including injectable nanocomposite hydrogels, electrosprayed nanoparticles, and waterborne polyurethane-based materials, are then discussed. The fourth section focuses on inorganic biomaterials, such as nanobioceramics, hydroxyapatite, and titanium dioxide. Finally, up-to-date information is provided on a wide range of smart natural biomaterials, ranging from silk fibroin-based scaffolds and collagen type I to chitosan, mussel-inspired biomaterials, and natural polymeric scaffolds. This is one of two books to be based on contributions from leading experts that were delivered at the 2018 Asia University Symposium on Biomedical Engineering in Seoul, Korea – the companion book examines in depth the latest enabling technologies for regenerative medicine.