N Heterocycles

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Copper in N-Heterocyclic Chemistry

Author : Ananya Srivastava
Publisher : Elsevier
Page : 506 pages
File Size : 45,6 Mb
Release : 2020-11-13
Category : Science
ISBN : 9780128215470

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Copper in N-Heterocyclic Chemistry by Ananya Srivastava Pdf

Copper in N-Heterocyclic Chemistry provides an overview of copper-catalyzed synthesis and functionalization of N-heterocyclic compounds, covering all recent developments in a way that is ideal for researchers and students working in the area of synthetic organic chemistry and medicinal chemistry. The book explores N-heterocyclic compounds as unique structural units in the development of natural products and pharmaceuticals, along with the remarkable progress made in the area of high atom economic strategies, and more recently, copper-catalyzed C-H activation and its applications in organic synthesis. Readers will find troubleshooting protocols, as well as the advantages and limitations of each method discussed. As copper catalysts show versatile chemical reactivity in many aspects, including their oxidation states 0–3 are accessible and their ability to facilitate bond formations due to their ability to serve as Lewis acids, oxidizing agents and catalysts, this book is an ideal resource on the topics explored. Discusses novel synthetic methods developed over the past decade for copper-catalyzed synthesis of N-heterocyclic compounds Covers the most recent methodologies adapted in synthetic chemistry for applications in natural products and pharmaceuticals Includes troubleshooting protocols, as well as the advantages and limitations of each method discussed in detail

More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles, 2 Volume Set

Author : Ana Maria Faisca Phillips
Publisher : John Wiley & Sons
Page : 759 pages
File Size : 45,5 Mb
Release : 2022-04-11
Category : Science
ISBN : 9781119757146

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More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles, 2 Volume Set by Ana Maria Faisca Phillips Pdf

More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles An authoritative collection of resources discussing the latest trends in the synthesis of nonaromatic nitrogen heterocycles Widely distributed in nature, nitrogen heterocycles are extremely common in synthetic substances found in pharmaceuticals, agrochemicals, and materials. The literature is evolving rapidly and explores newly emerging structures and medicines. More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles offers R&D professionals the opportunity to easily access a collection of the latest relevant research in the area. In the second two-volume set of this practical reference distinguished researcher Dr. Ana Maria M. M. Faisca Phillips delivers a collection of resources focusing on the newest and most widely applicable trends emerging in synthetic strategies for nonaromatic nitrogen heterocycles. With coverage of topics including organocatalysis, cascade reactions, flow chemistry in synthesis, cycloaddition reactions, metathesis, cross-coupling reactions, and electrochemistry, the book provides quick access to critical new avenues of synthesis. More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles: Volume 1 and 2 also offers readers: A thorough introduction to recent advances in the design and synthesis of cyclic peptidomimetics Comprehensive explorations of fused heterocycles and transition metal promoted synthesis of isoindoline derivatives Practical discussions of 1,4-diazepane ring-based systems and recent advances in the synthesis of azepane-based compounds In-depth examinations of strained aziridinium ions, asymmetric organocatalysis in alternative media, and the electrochemical synthesis of non-aromatic N-heterocycles Perfect for academic and industrial researchers in organic chemistry and synthesis, organometallic chemistry, pharmaceutical chemistry catalysis, and sustainable chemistry, More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles: Volume 1 and 2 is an indispensable reference for anyone seeking an authoritative source of information on new and emerging trends in synthesis.

N-Heterocyclic Carbenes in Organocatalysis

Author : Akkattu T. Biju
Publisher : John Wiley & Sons
Page : 407 pages
File Size : 42,7 Mb
Release : 2019-01-07
Category : Science
ISBN : 9783527809059

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N-Heterocyclic Carbenes in Organocatalysis by Akkattu T. Biju Pdf

Summarizing the emerging field of N-heterocyclic carbenes used in organocatalysis, this is an excellent overview of the synthesis and applications of NHCs focusing on carbon-carbon and carbon-heteroatom bond formation. Alongside comprehensive coverage of the synthesis, characteristics and applications, this handbook and ready reference also includes chapters on NHCs for polymerization reactions and natural product synthesis.

Ring Nitrogen and Key Biomolecules

Author : E.G. Brown
Publisher : Springer Science & Business Media
Page : 252 pages
File Size : 40,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789401149068

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Ring Nitrogen and Key Biomolecules by E.G. Brown Pdf

The nitrogen-containing ring structures are at the hub of metabolism and include ATP, nucleic acids, many coenzymes, metabolic regulators and integrators such as adenosine and GTP, signalling compounds such as cyclic nucleotides and plant cytokinins and biochemically functional pigmets of which haemoglobin, the cytochromes and chlorophyll are examples. This important book collates and integrates current knowledge of all the biologically important N-heterocyclic compounds, covering the relationship between their chemical structures and physiological functions within this key group of compounds. Few biochemical reaction sequences do not involve one of these compounds as a substrate, product or coenzyme and a full understanding of the interrelationship between their structure and function is vital for all those woorking in the field of biochemistry. Professor Eric Brown who has a huge wealth of experience in teaching and research on these compounds has written a very comprehensible and thorough book which will be of great value for advanced students and researchers in biochemistry and those at the interfacing subject areas of chemistry, biology and pharmacology including all those employed in researching biological function within pharmaceutical companies.

N-Heterocycles

Author : Keshav Lalit Ameta,Ravi Kant,Andrea Penoni,Angelo Maspero,Luca Scapinello
Publisher : Springer Nature
Page : 465 pages
File Size : 54,5 Mb
Release : 2022-04-23
Category : Science
ISBN : 9789811908323

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N-Heterocycles by Keshav Lalit Ameta,Ravi Kant,Andrea Penoni,Angelo Maspero,Luca Scapinello Pdf

This book presents an overview of the recent advancements for the synthesis of small- and medium-sized azaheterocycles, including pyrroles, indoles, pyrimidines, pyridines, pyrrolidines, imidazoles, pyrazoles, pyrazolines, lactams, and 1,2,3-triazoles, which are significant scaffolds for compounds with pharmaceutical uses. The book also discusses various properties and performance attributes of azaheterocycles including their bioactivity and synthetic strategies. Given the contents, the book will be a valuable reference for students, researchers, and professionals interested in organic synthesis and medicinal chemistry.

N-Sulfonated-N-Heterocycles

Author : Galal H. Elgemeie,Rasha A. Azzam,Wafaa A. Zaghary,Ashraf A. Aly,Nadia H Metwally,Mona O. Sarhan,Elshimaa M. Abdelhafez,Rasha E. Elsayed
Publisher : Elsevier
Page : 523 pages
File Size : 45,7 Mb
Release : 2022-08-30
Category : Science
ISBN : 9780128221822

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N-Sulfonated-N-Heterocycles by Galal H. Elgemeie,Rasha A. Azzam,Wafaa A. Zaghary,Ashraf A. Aly,Nadia H Metwally,Mona O. Sarhan,Elshimaa M. Abdelhafez,Rasha E. Elsayed Pdf

N-Sulfonated-N-Heterocycles covers the synthesis, chemistry and biological applications of these compounds, focusing on pioneering synthetic approaches, mechanistic insights and their limitations, as well as recent advances in this field. The synthesis of some of N-sulfonated N-heterocycles and their transformation to other useful cyclic and acyclic compounds are discussed, as well as their uses as useful intermediates in the preparation of polymeric and medicinal materials. This book includes detailed methods and protocols, and the focus on applications makes this resource an essential guide for all researchers in the area of organic, medicinal and polymeric synthetic study. Reviews the use of N-sulfonated N-heterocycles as important precursors for the synthesis of biologically active compounds Includes information on synthetically useful transformations of N-sulfonated N-heterocycles Covers a wide synthetic methods used for an important branch of heterocycles and their biological evaluation in detail Features over 500 schemes to illustrate different synthetic pathways and reactions of N-sulfonated N-heterocycles

Heterocyclic N-oxides

Author : Angelo Albini
Publisher : Routledge
Page : 323 pages
File Size : 46,8 Mb
Release : 2019-01-22
Category : Science
ISBN : 9781351441025

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Heterocyclic N-oxides by Angelo Albini Pdf

This book provides a comprehensive presentation of all aspects of heterocyclic N-oxides. Topics discussed include the preparation of these compounds by N-oxidation of heterocycles and simultaneous synthesis of the ring and formation of the N-oxide group; general spectroscopic characteristics and molecular structure; and reactions and recently devel

N-Sulfonated-N-Heterocycles

Author : Galal H. Elgemeie,Rasha A. Azzam,Wafaa A. Zaghary,Nadia H Metwally,Mona O. Sarhan,Elshimaa M. Abdelhafez,Rasha E. Elsayed
Publisher : Elsevier
Page : 522 pages
File Size : 50,6 Mb
Release : 2022-08-12
Category : Science
ISBN : 9780128221792

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N-Sulfonated-N-Heterocycles by Galal H. Elgemeie,Rasha A. Azzam,Wafaa A. Zaghary,Nadia H Metwally,Mona O. Sarhan,Elshimaa M. Abdelhafez,Rasha E. Elsayed Pdf

N-Sulfonated-N-Heterocycles covers the synthesis, chemistry and biological applications of these compounds, focusing on pioneering synthetic approaches, mechanistic insights and their limitations, as well as recent advances in this field. The synthesis of some of N-sulfonated N-heterocycles and their transformation to other useful cyclic and acyclic compounds are discussed, as well as their uses as useful intermediates in the preparation of polymeric and medicinal materials. This book includes detailed methods and protocols, and the focus on applications makes this resource an essential guide for all researchers in the area of organic, medicinal and polymeric synthetic study. Reviews the use of N-sulfonated N-heterocycles as important precursors for the synthesis of biologically active compounds Includes information on synthetically useful transformations of N-sulfonated N-heterocycles Covers a wide synthetic methods used for an important branch of heterocycles and their biological evaluation in detail Features over 500 schemes to illustrate different synthetic pathways and reactions of N-sulfonated N-heterocycles

Metals and Non-metals

Author : Navjeet Kaur
Publisher : CRC Press
Page : 404 pages
File Size : 41,7 Mb
Release : 2020-01-28
Category : Science
ISBN : 9781000733419

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Metals and Non-metals by Navjeet Kaur Pdf

Design of new processes that avoid the use of toxic reagents has been the focus of intense research of late. Catalysis by metals and non-metals offers diverse opportunities for the development of new organic reactions with promising range of selectivities—chemoselectivity, regioselectivity, diastereoselectivity, and enantioselectivity. Furthermore, these transformations frequently occur under mild conditions, tolerate a broad array of functional groups, and proceed with high stereoselectivity. The area of catalysis is sometimes referred to as a ‘foundational pillar’ of green chemistry. Catalytic reactions often reduce energy requirements and decrease separations because of increased selectivity; they are also capable of permitting the use of renewable feedstocks of less toxic reagents or minimizing the quantities of reagents needed. New catalytic organic synthesis methodologies have, thus, offered several possibilities for considerable improvement in the eco-compatibility of fine chemical production. Hence, these catalytic methodologies have emerged as powerful tools for the efficient and chemoselective synthesis of heterocyclic molecules. Key Features: Presents the synthesis of different five-membered heterocycles. Contains the most up-to-date information in this fast-moving field. Covers novel catalytic approaches used in the study and application of catalysts in synthetic organic reactions. Presents new methodologies for the synthesis of heterocycles.

More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles, 2 Volume Set

Author : Ana Maria Faisca Phillips
Publisher : John Wiley & Sons
Page : 759 pages
File Size : 40,8 Mb
Release : 2022-04-04
Category : Science
ISBN : 9781119757122

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More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles, 2 Volume Set by Ana Maria Faisca Phillips Pdf

More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles An authoritative collection of resources discussing the latest trends in the synthesis of nonaromatic nitrogen heterocycles Widely distributed in nature, nitrogen heterocycles are extremely common in synthetic substances found in pharmaceuticals, agrochemicals, and materials. The literature is evolving rapidly and explores newly emerging structures and medicines. More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles offers R&D professionals the opportunity to easily access a collection of the latest relevant research in the area. In the second two-volume set of this practical reference distinguished researcher Dr. Ana Maria M. M. Faisca Phillips delivers a collection of resources focusing on the newest and most widely applicable trends emerging in synthetic strategies for nonaromatic nitrogen heterocycles. With coverage of topics including organocatalysis, cascade reactions, flow chemistry in synthesis, cycloaddition reactions, metathesis, cross-coupling reactions, and electrochemistry, the book provides quick access to critical new avenues of synthesis. More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles: Volume 1 and 2 also offers readers: A thorough introduction to recent advances in the design and synthesis of cyclic peptidomimetics Comprehensive explorations of fused heterocycles and transition metal promoted synthesis of isoindoline derivatives Practical discussions of 1,4-diazepane ring-based systems and recent advances in the synthesis of azepane-based compounds In-depth examinations of strained aziridinium ions, asymmetric organocatalysis in alternative media, and the electrochemical synthesis of non-aromatic N-heterocycles Perfect for academic and industrial researchers in organic chemistry and synthesis, organometallic chemistry, pharmaceutical chemistry catalysis, and sustainable chemistry, More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles: Volume 1 and 2 is an indispensable reference for anyone seeking an authoritative source of information on new and emerging trends in synthesis.

Synthetic Approaches to Nonaromatic Nitrogen Heterocycles

Author : Ana Maria Faisca Phillips
Publisher : John Wiley & Sons
Page : 864 pages
File Size : 42,6 Mb
Release : 2020-11-18
Category : Science
ISBN : 9781119708759

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Synthetic Approaches to Nonaromatic Nitrogen Heterocycles by Ana Maria Faisca Phillips Pdf

A comprehensive overview of synthetic strategies for nonaromatic nitrogen heterocycles Nitrogen heterocycles are extremely widely distributed in nature, as well as in synthetic substances found in pharmaceuticals, agrochemicals, and materials chemistry. With new structures and medicines that include these structures emerging yearly, and a vast new journal literature to describe them, anyone who wants to be effective in R&D needs to easily access a synthesis of the latest research. This state-of-the-art survey explores recent developments in the most widely used reactions, as well as completely new ones. Highlights the major modern synthetic methods known to obtain nonaromatic nitrogen heterocycles, and their practical applications Topics include enantioselective synthesis and catalysis, photocatalysis, biocatalysis, microwave-assisted synthesis, reactions of oximes and nitrones, and ionic liquids Discusses how to synthesize rings of specific sizes Covers sustainable synthetic approaches for obtaining salts Whether you are using nonaromatic nitrogen compounds as an academic researcher, a synthetic chemist in industry, or an advanced student, this book is an essential, up-to-date resource to support your work.

Advances in Nitrogen Heterocycles

Author : C.J. Moody
Publisher : Elsevier
Page : 223 pages
File Size : 42,9 Mb
Release : 1999-01-19
Category : Science
ISBN : 0080560768

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Advances in Nitrogen Heterocycles by C.J. Moody Pdf

This volume contains a range of topics such as the activation and manipulation of pyrroles, the synthesis of annelated pyrroles using acylation reactions and the synthesis of kainoids, a family of highly biologically active nitrogen heterocycles.

Advances in Heterocyclic Chemistry

Author : Anonim
Publisher : Academic Press
Page : 378 pages
File Size : 55,8 Mb
Release : 1998-08-17
Category : Science
ISBN : 0080576583

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Advances in Heterocyclic Chemistry by Anonim Pdf

Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area--one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.

The Chemistry of Heterocycles

Author : Vishnu Ji Ram,Arun Sethi,Mahendra Nath,Ramendra Pratap
Publisher : Elsevier
Page : 503 pages
File Size : 54,5 Mb
Release : 2019-06-06
Category : Science
ISBN : 9780128192115

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The Chemistry of Heterocycles by Vishnu Ji Ram,Arun Sethi,Mahendra Nath,Ramendra Pratap Pdf

The Chemistry of Heterocycles: Chemistry of Six to Eight Membered N,O, S, P and Se Heterocycles details the chemistry, behavior and potential of these important structures. The book presents a practical guide to international nomenclature, including discussions of fused ring systems, heteroatoms with abnormal valences, and bridged, spiro and polycyclic heterocycles. Three membered heterocycles are then the focus, along with their thermodynamic properties and importance in natural products, medicines, materials, and their unique aspects, such as strain, basicity and reactivity. Additional chapters cover 100 key heterocycle structures, from Azetidines, Pyrroles and Pyridines, to Benzoxepines and Oxocanes. Final chapters explore cutting-edge advances in the development of phosphorus and selenium based heterocycles. Provides clear, detailed information on each heterocyclic group, including structural features, such as ring strain, basicity, synthesis and reactivity towards electrophilic and nucleophilic reagents Highlights the latest advances in the field, including phosphorous and selenium-based heterocycles supported by numerous illustrations Includes details of functionalized heterocycles used as synthons for the construction of various arenes and heteroarenes

Synthesis of 5-Membered Heterocycles

Author : Navjeet Kaur
Publisher : Elsevier
Page : 442 pages
File Size : 53,6 Mb
Release : 2023-09-22
Category : Science
ISBN : 9780443134241

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Synthesis of 5-Membered Heterocycles by Navjeet Kaur Pdf

Synthesis of Five-Membered Heterocycles: Role of DMF as Solvent, Reagent, Catalyst, and Stabilizer helps readers quickly assess possible synthetic approaches. The book's audience, researchers, academic professionals and synthetic chemists both in industry and academia will find detailed information about the synthesis of five-membered heterocyclic compounds using dimethylformamide. Over the years, heterocyclic compounds, especially five-membered, have drawn more attention of pharmaceutical community because of their therapeutic value. The formation of heterocyclic compounds has turned out to be the keystone of synthetic organic chemistry. Dimethylformamide has played an important role in organic synthesis for a long time, and it is frequently utilized as a common solvent for chemical reactions and broadly used in industry as a reagent. It is a unique chemical and can play three other roles in organic chemistry, i.e., as stabilizer, reagent and catalyst. Due to its structure, DMF can participate in several reactions as a versatile building block for several units. Includes comprehensive descriptions of heterocycle synthesis Highlights many methods for the synthesis of five-membered heterocyclic compounds using dimethylformamide Helps readers quickly assess possible synthetic approaches