Nano Pharmacokinetics And Theranostics

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Nano-Pharmacokinetics and Theranostics

Nanasaheb D. Thorat,Nitesh Kumar
Nano Pharmacokinetics and Theranostics Book PDF

Author : Nanasaheb D. Thorat,Nitesh Kumar
Publisher : Academic Press
Page : 324 pages
File Size : 41,5 Mb
Release : 2021-07-28
Category : Business & Economics
ISBN : 9780323859820

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Nano-Pharmacokinetics and Theranostics by Nanasaheb D. Thorat,Nitesh Kumar Pdf

Nano-Pharmacokinetics and Theranostics: Advancing Cancer Therapy addresses from a comprehensive and multidisciplinary approach the translational aspects and clinical perspectives of nano-pharmacokinetics using cancer as a model disease. Nano-pharmacokinetics is emerging as an important sub discipline of nanoscience and medical sciences because of the increasing safety issues of nanosystems on living organisms. This book reports the dynamics of nanosystems in living organisms for better understanding of nanotoxicity, pharmacology, biochemistry, physiology and medicine perspectives. It further examines current progress of state-of-the art pharmacokinetics mechanisms, which will be of great help to develop more clinical-oriented nanosystems with a wide safety margin. The book is divided into three sections: the first section focuses on the concept of pharmacokinetics with state-of-the-art Nano-Pharmacokinetics (NPK). The second section looks at the engineering of nanoparticles and pharmacokinetics clinical development. The final section focuses on Nano-Pharmacokinetics and Theranostics, elaborating the basic question of how pharmacokinetics of nanomaterials relate to their end applications such as cancer therapy. Nano-Pharmacokinetics and Theranostics: Advancing Cancer Therapy will be useful to researchers in the field of nanoparticle based targeted drug delivery including pharmaceutical scientists, material scientists, chemists, nanotechnologists, biomedical scientists, and clinicians. Includes contributions from highly qualified scientists, regulatory entities, enterprises and medical practitioners to explain the long and inherently multidisciplinary pathway of nano-pharmacokinetics Describes assessment methods of nano-pharmacokinetics Examines the interface between nanomedicine and pharmacokinetics to diagnose and treat cancer

Pharmacokinetics and Pharmacodynamics of Nanoparticulate Drug Delivery Systems

Jayvadan K. Patel,Yashwant V. Pathak
Pharmacokinetics and Pharmacodynamics of Nanoparticulate Drug Delivery Systems Book PDF

Author : Jayvadan K. Patel,Yashwant V. Pathak
Publisher : Springer Nature
Page : 437 pages
File Size : 52,7 Mb
Release : 2022-03-07
Category : Science
ISBN : 9783030833954

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Pharmacokinetics and Pharmacodynamics of Nanoparticulate Drug Delivery Systems by Jayvadan K. Patel,Yashwant V. Pathak Pdf

A reference is needed that addresses the recent progress in aspects of PK/PD methods and developments of nanoparticles for novel drug delivery systems. No other consolidated published reference discusses the PK/PD study of nanoparticle drug delivery systems. This book discusses the advantages of nanoparticle drug delivery systems (NPDDS) in enhancing the pharmacokinetics of many drugs that are not easily metabolized or that obtain the desired therapeutic effect with minimum toxicity. The authors provide an overview of biodistribution with a focus on polymer and lipid nanoparticles. This thorough reference is divided into three parts: Modelling, Specific carries and their potential to treat specific diseases.

Design of Nanostructures for Theranostics Applications

Alexandru Mihai Grumezescu
Design of Nanostructures for Theranostics Applications Book PDF

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Page : 692 pages
File Size : 45,6 Mb
Release : 2018-01-15
Category : Science
ISBN : 9780128136706

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Design of Nanostructures for Theranostics Applications by Alexandru Mihai Grumezescu Pdf

Design of Nanostructures for Theranostics Applications focuses on the theranostics applications of nanostructures. In particular, multifunctional nanoparticles for diagnostics and treatment of different diseases, including those relating to the blood-brain barrier, are discussed in detail. Chapters explore different type of nanostructures, covering design, fabrication, functionalization and optimization, helping readers obtain the desired properties. Written by a diverse range of international academics, this book is a valuable reference resource for those working in both nanoscience and the pharmaceutical industry. Explores how the design of a range of nanomaterials make them effective theranostic agents, including multifunctional core-shell nanostructures, mesoporous silica nanoparticles, and quantum dots Shows how nanomaterials are used effectively for a range of diseases, including breast cancer, prostate cancer and neurological disorders Assesses the pros and cons of using different nanomaterials for different types of treatment

Biogenic Nanoparticles for Cancer Theranostics

Chittaranjan Patra,Irshad Ahmad,Muhammad Ayaz,Ali Talha Khalil,Sudip Mukherjee,Muhammad Ovais
Biogenic Nanoparticles for Cancer Theranostics Book PDF

Author : Chittaranjan Patra,Irshad Ahmad,Muhammad Ayaz,Ali Talha Khalil,Sudip Mukherjee,Muhammad Ovais
Publisher : Elsevier
Page : 286 pages
File Size : 41,5 Mb
Release : 2021-05-18
Category : Technology & Engineering
ISBN : 9780128214688

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Biogenic Nanoparticles for Cancer Theranostics by Chittaranjan Patra,Irshad Ahmad,Muhammad Ayaz,Ali Talha Khalil,Sudip Mukherjee,Muhammad Ovais Pdf

Biogenic Nanoparticles for Cancer Theranostics outlines the synthesis of biogenic nanoparticles to become cancer theranostic agents. The book also discusses their cellular interaction and uptake, pharmacokinetics, biodistribution, drug delivery efficiency, and other biological effects. Additionally, the book explores the mechanism of their penetration in cancerous tissue, its clearance, and its metabolism. Moreover, the in vitro and in vivo toxicological effects of biogenic nanoparticles are discussed. This book is an important reference source for materials scientists and biomedical scientists who are looking to increase their understanding of how biogenic nanoparticles are being used for a range of cancer treatment types. Metal nanoparticles have traditionally been synthesized by classical physico-chemical methods which have many drawbacks, such as high energy demand, high cost and potential ecotoxicity. As a result, the biosynthesis of metal nanoparticles is gaining increasing prominence. Biosynthesis approaches to metal nanoparticles are clean, safe, energy efficient and environment friendly. Explains the synthesis methods and applications of biogenic nanoparticles for cancer theranostics Outlines the distinctive features of biogenic nanoparticles that make them effective cancer treatment agents Assesses the major challenges of using biogenic nanoparticles on a mass scale

Nanobiotechnology in Diagnosis, Drug Delivery and Treatment

Mahendra Rai,Mehdi Razzaghi-Abyaneh,Avinash P. Ingle
Nanobiotechnology in Diagnosis Drug Delivery and Treatment Book PDF

Author : Mahendra Rai,Mehdi Razzaghi-Abyaneh,Avinash P. Ingle
Publisher : John Wiley & Sons
Page : 416 pages
File Size : 47,9 Mb
Release : 2020-11-17
Category : Science
ISBN : 9781119671862

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Nanobiotechnology in Diagnosis, Drug Delivery and Treatment by Mahendra Rai,Mehdi Razzaghi-Abyaneh,Avinash P. Ingle Pdf

Presents nanobiotechnology in drug delivery and disease management Featuring contributions from noted experts in the field, this book highlights recent advances in the nano-based drug delivery systems. It also covers the diagnosis and role of various nanomaterials in the management of infectious diseases and non-infectious disorders, such as cancers and other malignancies and their role in future medicine. Nanobiotechnology in Diagnosis, Drug Delivery and Treatment starts by introducing how nanotechnology has revolutionized drug delivery, diagnosis, and treatments of diseases. It then focuses on the role of various nanocomposites in diagnosis, drug delivery, and treatment of diseases like cancer, Alzheimer's disease, diabetes, and many others. Next, it discusses the application of a variety of nanomaterials in the diagnosis and management of gastrointestinal tract disorders. The book explains the concept of nanotheranostics in detail and its role in effective monitoring of drug response, targeted drug delivery, enhanced drug accumulation in the target tissues, sustained as well as triggered release of drugs, and reduction in adverse effects. Other chapters cover aptamer-incorporated nanoparticle systems; magnetic nanoparticles; theranostics and vaccines; toxicological concerns of nanomaterials used in nanomedicine; and more. Provides a concise overview of state-of-the-art nanomaterials and their application like drug delivery in infectious diseases and non-infectious disorders Highlights recent advances in the nano-based drug delivery systems and role of various nanomaterials Introduces nano-based sensors which detect various pathogens Covers the use of nanodevices in diagnostics and theranostics Nanobiotechnology in Diagnosis, Drug Delivery and Treatment is an ideal book for researchers and scientists working in various disciplines such as microbiology, biotechnology, nanotechnology, pharmaceutical biotechnology, pharmacology, pharmaceutics, and nanomedicine.

Handbook of Nanomaterials for Cancer Theranostics

Joao Conde
Handbook of Nanomaterials for Cancer Theranostics Book PDF

Author : Joao Conde
Publisher : Elsevier
Page : 606 pages
File Size : 45,8 Mb
Release : 2018-06-27
Category : Science
ISBN : 9780128133408

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Handbook of Nanomaterials for Cancer Theranostics by Joao Conde Pdf

Handbook of Nanomaterials for Cancer Theranostics focuses on recent developments in advanced theranostic nanomedicines from a chemical and biological perspective where the advantages of theranostics are achieved by combining multiple components. The authors explore the pros and cons of theranostic nanomaterials developed in cancer research in the last 15 years, with the different strategies compared and scrutinized. In addition, the book explores how nanomaterials may overcome the regulatory hurdles facing theranostic nanomedicines. This is an important research reference for postgraduates and researchers in nanomedicine and cancer research who want to learn more on how nanomaterials can help create more effective cancer treatments. Highlights the development of smart theranostic nanomaterials to tackle biomedical problems in cancer therapy and diagnostics Explores the regulatory hurdles facing theranostic nanomedicine Discusses how the use of nanomaterials can help create more effective cancer treatments

Nanotheranostics for Personalized Medicine

Simona Mura,Patrick Couvreur
Nanotheranostics for Personalized Medicine Book PDF

Author : Simona Mura,Patrick Couvreur
Publisher : World Scientific
Page : 348 pages
File Size : 55,5 Mb
Release : 2016-02-22
Category : Medical
ISBN : 9789814713542

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Nanotheranostics for Personalized Medicine by Simona Mura,Patrick Couvreur Pdf

The application of nanotechnology in the biomedical field, known as nanomedicine, has gained much interest in the recent past as a versatile strategy for selective drug delivery and diagnostic purposes. The nanotheranostic approach, which aims to combine both therapeutic and imaging/diagnostic functionalities, is characterized by a strong pluridisciplinarity where the chemistry of materials, bioconjugate chemistry, pharmaceutical technology, drug delivery, imaging, and pharmacology, work together. Nanotheranostics combine simultaneous non-invasive diagnosis and treatment of diseases with the exciting possibility to monitor drug release and distribution in real time; thus offering the opportunity to optimize treatment outcomes in cancer and other severe diseases. Clinical applications of nanotheranostics would enable earlier detection and treatment of diseases, and earlier assessment of the response, thus allowing to identify patients which would potentially respond to therapy and have higher possibilities of a favorable outcome. Nanotheranostics for Personalized Medicine presents an integrated and transdisciplinary description of nanotheranostics. It provides principles of imaging techniques and concrete examples of advances and challenges in the development of nanotheranostics for personalized medicine. This book is written for students (Bachelors to Doctoral level) as well as experienced researchers, in academia or the industry, interested in this emerging concept in the nanomedicine field. Contents:Combining Imaging and Drug Delivery for the Treatment of Severe Diseases (Simona Mura and Patrick Couvreur)Increased Sensitivity for Medical Imaging Using Non-Ionizing Nanomedicine as Contrast Agents (Cyrille Richard, Bich-Thuy Doan and Nathalie Mignet)MRI T2 Weighted Theranostic Nanodevices and Chemotherapy (Sophie Laurent, Luce Vander Elst, Dimitri Stanicki and Robert N Muller)MRI T1 Weighted Theranostic Nanodevices (Lucie Sancey, François Lux, Géraldine Le Duc, Sabin Carme and Olivier Tillement)Optical Imaging and Chemotherapy (Guillaume Bort, Simona Mura and Patrick Couvreur)Plasmonic Nanoparticles-Coated Microbubbles for Theranostic Applications (Mark A Borden, Jacob D Dove and Todd W Murray)Contribution of Nuclear Medicine to Cancer Nanotheranostics (Thomas Lars Andresen, Anncatrine L Petersen, Anders E Hansen and Jonas R Henriksen)Nanotheranostics in Gene Therapy (Madhura Deshpande, Shravan Kumar Sriraman and Vladimir Torchilin)Nanotheranostics in Cardiovascular Diseases (Maya Juenet, Mariana Varna, Cédric Chauvierre and Didier Letourneur)Stimuli-Responsive Nanotheranostics (Basit Yameen, Jun Wu, Critian Vilos, Andrew Whyte David Werstler, Lori Pollit and Omid C Farokhzad)Advancing the Practical Clinical Utility in Personalized Medicine: Capabilities and Lessons Learned for Pharmacology and Pharmaceutics (Ioannis S Vizirianakis, Christina Karavasili, Elsa P Amanatiadou and Dimitrios G Fatouros) Readership: Advanced undergraduates, graduates, as well as experimental researchers in academia or the industry with an interest in this emerging concept in the nanomedicine world. Key Features:This book presents an integrated and transdisciplinary description of an emerging concept in the world of nanomedicine: nanotheranosticsThis work is one of the few dedicated to nanotheranostics and its applicationsWritten by well-recognized experts in academia, this book would offer to the reader a clear overview of the progresses in the field of nanotheranostics and their fundamental contribution to the field of personalized medicineReading this book would open the way to further improvements and to the possible clinical translation of the nanotheranostics concept in the not-too-distant futureKeywords:Bioengineering;Nanomedicine & Nanobiology;Biomedical Engineering;Medical Imaging;Therapy

Nanomedicines for Breast Cancer Theranostics

Nanasaheb D. Thorat,Joanna Bauer
Nanomedicines for Breast Cancer Theranostics Book PDF

Author : Nanasaheb D. Thorat,Joanna Bauer
Publisher : Elsevier
Page : 440 pages
File Size : 45,8 Mb
Release : 2020-03-08
Category : Technology & Engineering
ISBN : 9780128200179

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Nanomedicines for Breast Cancer Theranostics by Nanasaheb D. Thorat,Joanna Bauer Pdf

Nanomedicines for Breast Cancer Theranostics addresses the translational aspects and clinical perspectives of breast cancer nanomedicine from a multidisciplinary perspective. The book summarizes research efforts at the preclinical and clinical stage of nanostructures and nanomedicine for dealing with the important challenge of nanomedicine translation in breast cancer theranostics. This book is an important resource for those working in both academia and industry, focusing on hot topics in biomaterials, biomedical engineering, drug delivery and oncology. Shows how the discovery of new nanomedicines is leading directly to an increase in the early-stage diagnosis of breast cancer Includes coverage of breast cancer nanomedicine standardization and characterization, highlighting newly developed treatments, diagnostics and treatment monitoring tools Explains why the design of nanobiomaterials make them effective drug carriers when treating breast cancer

Theranostics and Image Guided Drug Delivery

Maya Thanou
Theranostics and Image Guided Drug Delivery Book PDF

Author : Maya Thanou
Publisher : Royal Society of Chemistry
Page : 254 pages
File Size : 50,8 Mb
Release : 2018-01-02
Category : Science
ISBN : 9781788013932

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Theranostics and Image Guided Drug Delivery by Maya Thanou Pdf

Molecular imaging of drugs or drug carriers is a valuable tool that can provide important information on spatiotemporal distribution of drugs, allowing improved drug distribution at target sites. Chemically labelled drugs can be used to both diagnose and treat diseases. This book introduces the topic of image guided drug delivery and covers the latest imaging techniques and developments in theranostics, highlighting the interdisciplinary nature of this field as well as its translational ability. These technologies and techniques hold potential for individualised, safer therapies. The book introduces the chemistry behind labelling drugs or drug carriers for imaging. It then discusses current scientific progress in the discovery and development of theranostic agents as well as the latest advances in triggered drug delivery. Novel imaging techniques that can be combined with therapeutics are presented, as well as results and findings from early clinical trials. This text will provide postgraduates and researchers in various disciplines associated with drug discovery, including chemistry, device engineering, oncology, neurology, cardiology, imaging, and nanoscience, an overview of this important field where several disciplines have been combined to improve treatments. Readers will be introduced to techniques that can be translated to the clinic and be applied widely.

Multifunctional Theranostic Nanomedicines in Cancer

Malay K. Das
Multifunctional Theranostic Nanomedicines in Cancer Book PDF

Author : Malay K. Das
Publisher : Academic Press
Page : 428 pages
File Size : 51,9 Mb
Release : 2021-03-16
Category : Business & Economics
ISBN : 9780128217009

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Multifunctional Theranostic Nanomedicines in Cancer by Malay K. Das Pdf

Multifunctional Theranostic Nanomedicines in Cancer focuses on new trends, applications, and the significance of novel multifunctional nanotheranostics in cancer imaging for diagnosis and treatment. Cancer nanotechnology offers new opportunities for cancer diagnosis and treatment. Multifunctional nanoparticles harboring various functions—including targeting, imaging, and therapy—have been intensively studied with the goal of overcoming the limitations of conventional cancer diagnosis and therapy. Thus theranostic nanomedicines have emerged in recent years to provide an efficient and safer alternative in cancer management. This book covers polymer-based therapies, lipid-based therapies, inorganic particle-based therapies, photo-related therapies, radiotherapies, chemotherapies, and surgeries. Multifunctional Theranostic Nanomedicines in Cancer offers an indispensable guide for researchers in academia, industry, and clinical settings; it is also ideal for postgraduate students; and formulation scientists working on cancer. Provides a comprehensive resource of recent scientific progress and novel applications of theranostic nanomedicines Discusses treatment options from a pharmaceutical sciences perspective Includes translational science and targeted CNS cancer treatment

Particles and Nanoparticles in Pharmaceutical Products

Henk G. Merkus,Gabriel M. H. Meesters,Wim Oostra
Particles and Nanoparticles in Pharmaceutical Products Book PDF

Author : Henk G. Merkus,Gabriel M. H. Meesters,Wim Oostra
Publisher : Springer
Page : 455 pages
File Size : 41,6 Mb
Release : 2018-09-06
Category : Technology & Engineering
ISBN : 9783319941745

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Particles and Nanoparticles in Pharmaceutical Products by Henk G. Merkus,Gabriel M. H. Meesters,Wim Oostra Pdf

This edited volume brings together the expertise of numerous specialists on the topic of particles – their physical, chemical, pharmacological and toxicological characteristics – when they are a component of pharmaceutical products and formulations. The book discusses in detail properties such as the composition, size, shape, surface properties and porosity of particles with respect to how they impact the formulations and products in which they are used and the effective delivery of pharmaceutical active ingredients. It considers all dosage forms of pharmaceuticals involving particles, from powders to tablets, creams to ointments, and solutions to dry-powder inhalers, also including the latest nanomedicine products. Further, it discusses examples of particle toxicity, as well as the important subject of pharmaceutical industry regulations, guidelines and legislation. The book is of interest to researchers and practitioners who work on testing and developing pharmaceutical dosage and delivery systems.

Cancer Nanotechnology

Anonim
Cancer Nanotechnology Book PDF

Author : Anonim
Publisher : Academic Press
Page : 222 pages
File Size : 48,8 Mb
Release : 2018-06-23
Category : Medical
ISBN : 9780128141700

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Cancer Nanotechnology by Anonim Pdf

Advances in Cancer Research, Volume 139, provides invaluable information on the exciting and fast-moving field of cancer research. Original reviews are presented on a variety of topics relating to the rapidly developing intersection between nanotechnology and cancer research, with unique sections in the new release focusing on Exosomes as a theranostic for lung cancer, Nanotechnology and cancer immunotherapy, Ultrasound imaging agents and delivery systems, Dendronized systems for the delivery of chemotherapeutics, Thermosensitive liposomes for image-guided drug delivery, Supramolecular Chemistry in Tumor Analysis and Drug Delivery, Gold nanoparticles for delivery of cancer therapeutics, and Single cell barcode microchip for cancer research and therapy. Provides the latest information on cancer research Offers outstanding and original reviews on a range of cancer research topics Serves as an indispensable reference for researchers and students alike

Microbial Interactions at Nanobiotechnology Interfaces

R. Navanietha Krishnaraj,Rajesh K. Sani
Microbial Interactions at Nanobiotechnology Interfaces Book PDF

Author : R. Navanietha Krishnaraj,Rajesh K. Sani
Publisher : John Wiley & Sons
Page : 416 pages
File Size : 44,6 Mb
Release : 2021-10-26
Category : Technology & Engineering
ISBN : 9781119617174

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Microbial Interactions at Nanobiotechnology Interfaces by R. Navanietha Krishnaraj,Rajesh K. Sani Pdf

MICROBIAL INTERACTIONS AT NANOBIOTECHNOLOGY INTERFACES This book covers a wide range of topics including synthesis of nanomaterials with specific size, shape, and properties, structure-function relationships, tailoring the surface of nanomaterials for improving the properties, interaction of nanomaterials with proteins/microorganism/eukaryotic cells, and applications in different sectors. This book also provides a strong foundation for researchers who are interested to venture into developing functionalized nanomaterials for any biological applications in their research. Practical concepts such as modelling nanomaterials, and simulating the molecular interactions with biomolecules, transcriptomic or genomic approaches, advanced imaging techniques to investigate the functionalization of nanomaterials/interaction of nanomaterials with biomolecules and microorganisms are some of the chapters that offer significant benefits to the researchers.

Nanotheranostics

Mahendra Rai,Bushra Jamil
Nanotheranostics Book PDF

Author : Mahendra Rai,Bushra Jamil
Publisher : Springer Nature
Page : 413 pages
File Size : 48,6 Mb
Release : 2019-11-22
Category : Medical
ISBN : 9783030297688

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Nanotheranostics by Mahendra Rai,Bushra Jamil Pdf

This book is specifically designed to provide information about various nanocarriers currently developed under the emerging field of nanotheranostics for a sustained, controlled, and targeted co-delivery of diagnostic and therapeutic agents. Diverse theranostic applications of nanotechnology and their limitations are also addressed. It integrates nanobiotechnology with theranostic applications. The combined term nanotheranostics has diverse application particularly in chemotherapy and other infectious diseases.Among other topics addressed are antimicrobial resistance, targeting intra-cellular pathogens, viruses and bacteria, chemotherapy, cancer therapeutics, and inflammatory disorders. This interdisciplinary volume is essential for a diverse group of readers including nanotechnologists, microbiologists, biotechnologists, bioengineering and bioprocess industry.

NanoBioMedicine

Shailendra K. Saxena,S. M. Paul Khurana
NanoBioMedicine Book PDF

Author : Shailendra K. Saxena,S. M. Paul Khurana
Publisher : Springer Nature
Page : 510 pages
File Size : 45,7 Mb
Release : 2020-02-03
Category : Medical
ISBN : 9789813298989

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NanoBioMedicine by Shailendra K. Saxena,S. M. Paul Khurana Pdf

This book provides a comprehensive overview of the recent trends in various Nanotechnology-based therapeutics and challenges associated with its development. Nanobiotechnology is an interdisciplinary research that has wide applications in the various fields of biomedical research. The book discusses the various facets of the application of Nanotechnology in drug delivery, clinical diagnostics, Nanomedicine and treatment of infectious and chronic diseases. The book also highlights the recent advancements on important devices and applications that are based on Nanotechnology in medicine and brief the regulatory and ethical issues related to nanomedical devices. It also reviews the toxicological profile of various nanomaterials and emphasizes the need for safe nanomaterials for clinical use. Finally, the book discusses the recent developments of potential commercial applications of Nanotechnology.