Nanotoxicology

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Nanotoxicology

Nelson Durán,Silvia S. Guterres,Oswaldo L. Alves
Nanotoxicology Book PDF

Author : Nelson Durán,Silvia S. Guterres,Oswaldo L. Alves
Publisher : Springer Science & Business Media
Page : 411 pages
File Size : 41,6 Mb
Release : 2013-10-25
Category : Medical
ISBN : 9781461489931

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Nanotoxicology by Nelson Durán,Silvia S. Guterres,Oswaldo L. Alves Pdf

This book takes a systematic approach to nanotoxicology and the developing risk factors associated with nanosized particles during manufacture and use of nanotechnology. Beginning with a detailed introduction to engineered nanostructures, the first part of the book presents concepts and definitions of nanomaterials from quantum dots to graphene to fullerenes, with detailed discussion of functionalization, stability, and medical and biological applications. The second part critically examines methodologies used to assess cytotoxicity and genotoxicity. Coverage includes interactions with blood (erythrocytes), combinatorial and microarray techniques, cellular mechanisms, and ecotoxicology assessments. Part three describes cases studies both in vitro and in vivo for specific nanomaterials including solid lipid nanoparticles and nanostructured lipid carriers and metallic nanoparticles and metallic oxides. New information is also presented on toxicological aspects of poloxamers and polymeric nanoparticles as drug carriers as well as size effects on cytotoxicity and genotoxicity. Didactic aspects are emphasized in all chapters, making the book suitable for a broad audience ranging from advanced undergraduate and graduate students to researchers in academia and industry. In all, Nanotoxicology: Materials, Methodologies, and Assessments will provide comprehensive insight into biological and environmental interactions with nanostructures. Provides an introduction to nanostructures actually in use Describes cyto- and genotoxicity methodologies, and assesses their performance in comparison to common toxicity assays Discusses the relation of cytotoxicity and genotoxicity to ecotoxicity Presents a range of applications, from biogenic silver nanoparticles to poloxamers as drug-delivery systems, reflecting the expanding applications of nanotechnology

Nanotoxicology

Alok Dhawan,Diana Anderson,Rishi Shanker
Nanotoxicology Book PDF

Author : Alok Dhawan,Diana Anderson,Rishi Shanker
Publisher : Royal Society of Chemistry
Page : 380 pages
File Size : 45,7 Mb
Release : 2017-11-13
Category : Science
ISBN : 9781782621584

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Nanotoxicology by Alok Dhawan,Diana Anderson,Rishi Shanker Pdf

This book fills the significant nanotoxicology and nanosafety knowledge gaps and covers a broad range of topics. It targets postgraduates, academics, and practicing industrialists.

Nanotoxicology

Hemant Kumar Daima,S. L. Kothari,Bhargava Suresh Kumar
Nanotoxicology Book PDF

Author : Hemant Kumar Daima,S. L. Kothari,Bhargava Suresh Kumar
Publisher : CRC Press
Page : 494 pages
File Size : 51,7 Mb
Release : 2021-07-15
Category : Medical
ISBN : 9781000399912

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Nanotoxicology by Hemant Kumar Daima,S. L. Kothari,Bhargava Suresh Kumar Pdf

The field of nanomedicine has risen quickly due to the increasing number of designer-made nanomaterials. These nanomaterials have the potential to manage diseases and change the way medicine is currently studied. However, the increased practice of using nanomaterials has shed light on how many concepts of nanomedicine and nanotoxicity have been overlooked. Nanotoxicology: Toxicity Evaluation of Nanomedicine Applications addresses the existing gaps between nanomedicine and nanotoxicity. This book also brings together up-to-date knowledge on advances toward safe-by-design nanomaterials and existing toxicity challenges. This book delivers a comprehensive coverage in the field with fundamental understanding, serving as a platform to convey essential concepts of nanotoxicology and how these concepts can be employed to develop advanced nanomaterials for a range of biomedical applications. This book is an effort to answer some of the thoughtful nanotoxicological complications and their auspicious probable solutions with new approaches and careful toxicity assessment. Key Features: Reveals novel nanoscale approaches, toxicity assessment, and biomedical applications Includes importance of nanotoxicity concepts in developing smart nanomaterials Highlights unique contributions and "A to Z" aspects on the state-of-the-art from global leaders Offers a complete package to learn fundamentals with recommendations on nanomaterials toxicity and safe-by-design nanomedicines Nanotoxicology: Toxicity Evaluation of Nanomedicine Applications illuminates the high potential of many innovative nanomaterials, ultimately demonstrating them to be promising substitutes for available therapies that can be effectively used in fighting a myriad of biomedical complications. Further, this book reports legal, ethical, safety, and regulatory issues associated with nanomaterials, which have often been neglected, if not overlooked in literature and limiting clinical translation at nanoscale level. It will equip readers with cutting-edge knowledge of promising developments in nanomedicine and nanotoxicology, along with potential future prospects.

Nanotoxicology

Nancy A. Monteiro-Riviere,C. Lang Tran
Nanotoxicology Book PDF

Author : Nancy A. Monteiro-Riviere,C. Lang Tran
Publisher : CRC Press
Page : 452 pages
File Size : 47,8 Mb
Release : 2007-07-25
Category : Medical
ISBN : 9781420045154

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Nanotoxicology by Nancy A. Monteiro-Riviere,C. Lang Tran Pdf

Nanomaterials - structures with characteristic dimensions between 1 and 100 nm -exhibit a variety of unique and tunable chemical and physical properties that have made engineered nanoparticles central components in an array of emerging technologies. The use of nanotechnology is increasing; however its potential adverse effects on human health are n

Computational Nanotoxicology

Agnieszka Gajewicz,Tomasz Puzyn
Computational Nanotoxicology Book PDF

Author : Agnieszka Gajewicz,Tomasz Puzyn
Publisher : CRC Press
Page : 570 pages
File Size : 49,9 Mb
Release : 2019-11-13
Category : Medical
ISBN : 9781000680881

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Computational Nanotoxicology by Agnieszka Gajewicz,Tomasz Puzyn Pdf

The development of computational methods that support human health and environmental risk assessment of engineered nanomaterials (ENMs) has attracted great interest because the application of these methods enables us to fill existing experimental data gaps. However, considering the high degree of complexity and multifunctionality of ENMs, computational methods originally developed for regular chemicals cannot always be applied explicitly in nanotoxicology. This book discusses the current state of the art and future needs in the development of computational modeling techniques for nanotoxicology. It focuses on (i) computational chemistry (quantum mechanics, semi-empirical methods, density functional theory, molecular mechanics, molecular dynamics), (ii) nanochemoinformatic methods (quantitative structure–activity relationship modeling, grouping, read-across), and (iii) nanobioinformatic methods (genomics, transcriptomics, proteomics, metabolomics). It reviews methods of calculating molecular descriptors sufficient to characterize the structure of nanoparticles, specifies recent trends in the validation of computational methods, and discusses ways to cope with the uncertainty of predictions. In addition, it highlights the status quo and further challenges in the application of computational methods in regulation (e.g., REACH, OECD) and in industry for product development and optimization and the future directions for increasing acceptance of computational modeling for nanotoxicology.

Environmental Nanotoxicology

Patrick Omoregie Isibor,Geetha Devi,Alex Ajeh Enuneku
Environmental Nanotoxicology Book PDF

Author : Patrick Omoregie Isibor,Geetha Devi,Alex Ajeh Enuneku
Publisher : Springer Nature
Page : 358 pages
File Size : 40,6 Mb
Release : 2024
Category : Electronic books
ISBN : 9783031541544

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Environmental Nanotoxicology by Patrick Omoregie Isibor,Geetha Devi,Alex Ajeh Enuneku Pdf

Environmental Nanotoxicology: Combatting the Minute Contaminants is a comprehensive guide to the rapidly evolving field of nanotoxicology and its implications for environmental health and safety. This book results from the collaborative efforts of leading experts and researchers from diverse disciplines, aiming to thoroughly understand the interactions between nanomaterials and the environment and their potential impacts on the delicate balance of our ecosystems. Nanotechnology has witnessed remarkable innovations leading to the development of nanomaterials with novel properties and applications across various industries. Alongside these innovations, concerns have arisen about the potential risks that nanomaterials may pose to the environment and living organisms. This book addresses these concerns by comprehensively exploring the field's key concepts, principles, and methodologies. It includes case studies and offers insights into developing appropriate regulatory frameworks and guidelines for the responsible use and disposal of nanomaterials. The book is a valuable resource for researchers and professionals working in nanotoxicology on the complex challenges posed by the intersection of nanomaterials and the environment. It is also an essential reference for students studying environmental science, toxicology, and nanotechnology. Addresses risk assessment and management in nanotoxicology; Explores the life cycle assessment of nanoparticles; Sheds light on emerging technologies and future directions in environmental nanotoxicology. .

Nanotoxicology

Vineet Kumar,Nandita Dasgupta,Shivendu Ranjan
Nanotoxicology Book PDF

Author : Vineet Kumar,Nandita Dasgupta,Shivendu Ranjan
Publisher : CRC Press
Page : 684 pages
File Size : 43,8 Mb
Release : 2018-03-12
Category : Medical
ISBN : 9781351138192

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Nanotoxicology by Vineet Kumar,Nandita Dasgupta,Shivendu Ranjan Pdf

As the application of nanotechnology in the myriad disciplines of science and engineering--from agriculture, pharmaceuticals, material science, and biotechnology to sensors, electronics, and mechanical and electrical engineering--brings benefits it also can produce serious threats to human health and the environment that must be evaluated. The unique properties of nanomaterials make them different from their bulk counterparts. In addition to such unique properties, the nanometric size of nanomaterials can invite some detrimental effects on the health and well-being of living organisms and the environment. Thus, it is important to distinguish nanomaterials with such ill effects from nanomaterials with no or minimum toxicity. Nanotoxicology: Toxicity Evaluation, Risk Assessment and Management covers issues such as the basic principles of nanotoxicity, methods used for nanotoxicity evaluation, risk assessment and its management for nanomaterial toxicity with a focus on current trends, limitations, challenges, and future directions of nanotoxicity evaluation. Various experts from different countries discuss these issues in detail in this book. This will be helpful to researchers, educators, and students who are interested in research opportunities for avoiding the environmental and health hazards of nanomaterials. This book will also be useful for industrial practitioners, policy makers, and other professionals in the fields of toxicology, medicine, pharmacology, food, drugs, and other regulatory sciences.

Nanotoxicology

Nancy A. Monteiro-Riviere,C. Lang Tran
Nanotoxicology Book PDF

Author : Nancy A. Monteiro-Riviere,C. Lang Tran
Publisher : CRC Press
Page : 516 pages
File Size : 40,9 Mb
Release : 2014-03-03
Category : Medical
ISBN : 9781482203875

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Nanotoxicology by Nancy A. Monteiro-Riviere,C. Lang Tran Pdf

Since the first publication of this book in 2007, the field of nanoscience and nanomedicine continues to grow substantially. This second edition, Nanotoxicology: Progress toward Nanomedicine, enlists internationally recognized experts to document the continuing development and rationale for the safe design of engineered nanomaterials (ENM). This includes new improved characterization endpoints, screening, and detection methods for in vitro and in vivo toxicity testing. These tools also contribute greatly to nanosafety research applied to nanomedicines. Topics include The impacts of nanotechnology on biomedicine, including functionalization for tissue-specific targeting, the biointeractions of multifunctional nanoparticle-based therapy, and the ability to control specific physicochemical properties of nanoparticles The requirements for proper detection, measurement, and assessment both for workplace exposure and in consumer products—with a focus on potential health and safety implications Predictive modeling, using quantitative nanostructure activity relationships to predict the pharmacokinetics and biodistribution of nanomaterials in the body Specific methodologies, imaging, and techniques to assess nanomaterials from the manufacturing process to nanomedicine applications Tools for assessing nanoparticle toxicity and the limitations of detection methods for assessing toxicity in both in vivo and in vitro systems and at the single cell and tissue levels Toxicity of nanomaterials to specific organ systems, cell–based targeting to tumors, and other biomedical applications The difficulty of conducting risk assessments and the need for addressing knowledge gaps, especially with long-term studies A roadmap for future research The development of nanotechnology-based products must be complemented with appropriate validated methods to assess, monitor, manage, and reduce the potential risks of ENM to human health and the environment. This volume provides a cogent survey of advances in this area by a well-respected and diverse group of international scientists.

Nanotoxicology and Nanoecotoxicology Vol. 2

Vineet Kumar,Praveen Guleria,Shivendu Ranjan,Nandita Dasgupta,Eric Lichtfouse
Nanotoxicology and Nanoecotoxicology Vol 2 Book PDF

Author : Vineet Kumar,Praveen Guleria,Shivendu Ranjan,Nandita Dasgupta,Eric Lichtfouse
Publisher : Springer Nature
Page : 305 pages
File Size : 40,5 Mb
Release : 2021-05-25
Category : Science
ISBN : 9783030694920

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Nanotoxicology and Nanoecotoxicology Vol. 2 by Vineet Kumar,Praveen Guleria,Shivendu Ranjan,Nandita Dasgupta,Eric Lichtfouse Pdf

This book reviews advances in the toxicity of nanomaterials, with a focus on nanosensors and nanotoxicity testing, biomagnification, biotransformation, nanosafety, genotoxicity, human health and remediation. This is the second volume on Nanotoxicology and Nanoecotoxicology published in the book series Environmental Chemistry for a Sustainable World.

Nanotoxicology in Caenorhabditis elegans

Dayong Wang
Nanotoxicology in Caenorhabditis elegans Book PDF

Author : Dayong Wang
Publisher : Springer
Page : 0 pages
File Size : 43,6 Mb
Release : 2019-02-11
Category : Medical
ISBN : 9811343659

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Nanotoxicology in Caenorhabditis elegans by Dayong Wang Pdf

This book focuses on the toxicity of engineered nanomaterials (ENMs) and their underlying physicochemical, cellular, physiological, and molecular mechanisms. Further, it covers ENMs’ translocation and their targeted organ toxicology, and discusses chemical and pharmacological strategies used to combat nanotoxicity. Engineered nanomaterials (ENMs) are defined as materials with one or more dimensions of less than 100 nm, and have shown considerable promise in several areas of development. At the same time, the potential toxicity of ENMs for human health and environmental organisms is increasingly attracting attention. In addition to the typical properties of model animals, Caenorhabditis elegans is extremely sensitive to environmental toxicants, which makes it the ideal in vivo assay system for toxicological studies. C. elegans has been widely used in toxicity assessment and toxicological studies of environmental toxicants and stresses. This book provides a comprehensive summary of nanotoxicology research on C. elegans.

Nanotoxicology for Agricultural and Environmental Applications

Mahendra Rai,Indarchand Gupta
Nanotoxicology for Agricultural and Environmental Applications Book PDF

Author : Mahendra Rai,Indarchand Gupta
Publisher : Elsevier
Page : 325 pages
File Size : 45,5 Mb
Release : 2024-03-28
Category : Technology & Engineering
ISBN : 9780443155710

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Nanotoxicology for Agricultural and Environmental Applications by Mahendra Rai,Indarchand Gupta Pdf

Published as part of Elsevier’s series, Nanobiotechnology for Plant Protection, Nanotoxicology for Agricultural and Environmental Applications provides an introduction to nanotechnology and its applications in agriculture and the environment.Divided into five parts, this book addresses nanotechnology and regulations, nanotoxicity, nanotoxicity to agriculture and food, nanotoxicity to the environment, and risk management measures to avoid exposure.Students, practitioners, and researchers working in plant science, agricultural science, nanoscience, and environmental chemistry alike will benefit from this necessary reference. Highlights the factors contributing to toxic effects of nanoparticles, including shape, size, structure, surface charge, and dosage Explores the mode of action and entry of nanoparticles, methods of toxicity evaluation, and the associated challenges Describes recent developments in nanotoxicity to soil ecosystems, crop plants, and food systems Emphasizes the impact of nanoparticles and their detoxification by plants on the nutritional quality of food and plants Discusses the impact of toxicity of nanoparticles released in air, soil, and water and methods to reduce their effects

Nanoethics and Nanotoxicology

Philippe Houdy,Marcel Lahmani,Francelyne Marano
Nanoethics and Nanotoxicology Book PDF

Author : Philippe Houdy,Marcel Lahmani,Francelyne Marano
Publisher : Springer Science & Business Media
Page : 620 pages
File Size : 43,9 Mb
Release : 2011-09-13
Category : Science
ISBN : 9783642201776

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Nanoethics and Nanotoxicology by Philippe Houdy,Marcel Lahmani,Francelyne Marano Pdf

Nanobiotechnology is a fast developing field of research and application in many domains such as in medicine, pharmacy, cosmetics and agro-industry. The book addresses the lastest fundamental results on nanotoxicology and nanoethics, and the enormous range of potential applications in the fields of medical diagnostics, nanomedicine, and food and water administration. Nanoscale objects have properties leading to specific kinds of behaviour, sometimes exacerbating their chemical reactivity, physical behaviour, or potential to penetrate deeply within living organisms. Hence it is important to ensure the responsible and safe development of nanomaterials and nanotechnologies. This fourth volume in the Nanoscience series should make its mark, by presenting the state of the art in the fields of nanotoxicology and nanoethics. This is the first book to combine both scientific knowledge and ethical and social recommendations. It also presents specific policies on nanotechnologies set up by national and international authorities. This book is of interest to engineers, researchers, and graduate students.

Nanotoxicology in Caenorhabditis elegans

Dayong Wang
Nanotoxicology in Caenorhabditis elegans Book PDF

Author : Dayong Wang
Publisher : Springer
Page : 274 pages
File Size : 43,9 Mb
Release : 2018-05-22
Category : Medical
ISBN : 9789811302336

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Nanotoxicology in Caenorhabditis elegans by Dayong Wang Pdf

This book focuses on the toxicity of engineered nanomaterials (ENMs) and their underlying physicochemical, cellular, physiological, and molecular mechanisms. Further, it covers ENMs’ translocation and their targeted organ toxicology, and discusses chemical and pharmacological strategies used to combat nanotoxicity. Engineered nanomaterials (ENMs) are defined as materials with one or more dimensions of less than 100 nm, and have shown considerable promise in several areas of development. At the same time, the potential toxicity of ENMs for human health and environmental organisms is increasingly attracting attention. In addition to the typical properties of model animals, Caenorhabditis elegans is extremely sensitive to environmental toxicants, which makes it the ideal in vivo assay system for toxicological studies. C. elegans has been widely used in toxicity assessment and toxicological studies of environmental toxicants and stresses. This book provides a comprehensive summary of nanotoxicology research on C. elegans.

Nanopharmacology and Nanotoxicology: Clinical Implications and Methods

Elham Ahmadian,Magali Cucchiarini,Aziz Eftekhari
Nanopharmacology and Nanotoxicology Clinical Implications and Methods Book PDF

Author : Elham Ahmadian,Magali Cucchiarini,Aziz Eftekhari
Publisher : Bentham Science Publishers
Page : 288 pages
File Size : 44,5 Mb
Release : 2023-05-31
Category : Medical
ISBN : 9789815079708

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Nanopharmacology and Nanotoxicology: Clinical Implications and Methods by Elham Ahmadian,Magali Cucchiarini,Aziz Eftekhari Pdf

This book explains key concepts and applications of nanotechnology in clinical medicine and pharmacology. The chapters have been contributed by experts and provide a broad perspective about the current and future developments in pharmacology, toxicology, cell biology, and materials science. The book is divided into 2 main sections. The first section concerns nanobiotechnology for human health including gastrointestinal disease, kidney diseases, pulmonary disorders, reproductive system, COVID-19, and cancer. The second section is devoted to toxicological aspects of nanomaterials which involve toxicological assessments of nanotherapeutics and potential solutions for nanotoxicology. Key Features - Emphasizes the high degree of interdisciplinary research in pharmacology, toxicology and nanoscience - Summarizes the results of theoretical, methodological, and practical studies in different medical subspecialties - includes special topics such as novel nanotoxicology assessment methods and nano vaccines - Includes references for further reading

Case Studies in Nanotoxicology and Particle Toxicology

Antonietta M Gatti,Stefano Montanari
Case Studies in Nanotoxicology and Particle Toxicology Book PDF

Author : Antonietta M Gatti,Stefano Montanari
Publisher : Academic Press
Page : 276 pages
File Size : 43,7 Mb
Release : 2015-05-29
Category : Medical
ISBN : 9780128012543

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Case Studies in Nanotoxicology and Particle Toxicology by Antonietta M Gatti,Stefano Montanari Pdf

Case Studies in Nanotoxicology and Particle Toxicology presents a highly-illustrated analysis of the most prominent cases on the adverse effects of nanoparticles and their impact on humans and the environment. This comprehensive reference demonstrates the possible risks imposed by managing and handling nanoparticles, showing the effects of involuntary inhalation or ingestion during their use and after their incineration. Through the use of numerous examples, readers will discover the possible risks and effects of working with nanoparticles, along with best practices to prevent these effects. The text is an essential reference for anyone working in the risk assessment of nanoparticles, including nanosafety professionals, occupational toxicologists, regulatory toxicologists, and clinicians. Presents real-life cases showing the potential risks to human health following exposure to nanoparticles An ideal reference for anyone working in the risk assessment of nanoparticles, including nanosafety professionals, occupational toxicologists, regulatory toxicologists, and clinicians Provides examples to help assess risks of handling engineered nanomaterials Advises on the best forms of protection and the safest nanotechnological products