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This book introduces the new concept of “nanozyme”, which refers to nanomaterials with intrinsic enzymatic activity, rather than nanomaterials with biological enzymes incorporated on the surface. The book presents the cutting-edge advances in nanozyme, with emphasis on state-of-the-art applications in many important fields, such as in the biomedical fields and for environmental protection. The nanozyme is a totally new type of artificial enzyme and exhibits huge advantages over natural enzymes, including greater stability, low cost, versatility, simplicity, and suitability for industry. It is of interest to university researchers, R&D engineers, as well as graduate students in nanoscience and technology, and biology wishing to learn the core principles, methods, and the corresponding applications of “nanozyme”.
This book presents the state-of-the-art advances and applications of nanozymes, the recently developing branch of enzymology that synthesizes and uses nanomaterials that mimic the function of traditional enzymes. During the past decade, the study of nanozymes has grown rapidly. Several new nanomaterials that exhibit enzymatic actions have been identified, along with new applications for their practical use. This book draws upon the work of experts from around the world and provides an in-depth analysis and cutting-edge overview of nanozymes, with an eye toward their present and future applications. Chapters are arranged in a logical order to provide physio-chemical characterization of nanozyme and basic mechanisms of their enzymatic actions. Focusing on current limitations of nanozymes and their reaction kinetics, the book presents a comprehensive discourse on nanozyme engineering that includes possible surface modifications to enhance nanozyme effectiveness. It also focuses on traditional and novel nanozyme applications, such as biosensing, drug delivery, and disease therapy, as well as their use as antibacterials. An important addition in this book is the summary of emerging literature on nanozyme toxicology. This book is intended as a ready reference for advanced undergraduate and graduate students doing research in nanotechnology; materials science; chemistry; and chemical, biological, biomedical, and food engineering. Research and development scientists, engineers, and technologists working in the chemical and biological/biomedical industries will gain much from the materials in this book for their industry practice. Presents a comprehensive discourse on nanozyme engineering that includes possible surface modifications to enhance nanozyme effectiveness. Discusses metal organic frameworks as nanozymes. Reviews on traditional and novel nanozyme applications, such as biosensing, drug delivery, disease therapy, and their use as antibacterials. Examines nanozyme toxicology. Dr. Sundaram Gunasekaran is a Professor in the Department of Biological Systems Engineering at the University of Wisconsin–Madison.
Nano-Enzyme Incorporated Particles by Veleeswaran Ananthi,Alagarsamy Arun,Chaudhery Mustansar Hussain Pdf
Approx.296 pages Focuses on integrative approaches of the enzyme nanoparticle synthesis and its applications on biomedicine, biosensors, and biocatalysis Encloses the potential challenges and developments of enzyme incorporated nanoparticles Discusses the vital activities of nanozymes in enzyme mimicking processes and prudent bio-catalytic efficiency Covers the latest methods and procedures involved in enzyme-incorporated nanomaterials
Nanozymes: Next Wave of Artificial Enzymes by Xiaoyu Wang,Wenjing Guo,Yihui Hu,Jiangjiexing Wu,Hui Wei Pdf
This book describes the fundamental concepts, the latest developments and the outlook of the field of nanozymes (i.e., the catalytic nanomaterials with enzymatic characteristics). As one of today’s most exciting fields, nanozyme research lies at the interface of chemistry, biology, materials science and nanotechnology. Each of the book’s six chapters explores advances in nanozymes. Following an introduction to the rise of nanozymes research in the course of research on natural enzymes and artificial enzymes in Chapter 1, Chapters 2 through 5 discuss different nanomaterials used to mimic various natural enzymes, from carbon-based and metal-based nanomaterials to metal oxide-based nanomaterials and other nanomaterials. In each of these chapters, the nanomaterials’ enzyme mimetic activities, catalytic mechanisms and key applications are covered. In closing, Chapter 6 addresses the current challenges and outlines further directions for nanozymes. Presenting extensive information on nanozymes and supplemented with a wealth of color illustrations and tables, the book offers an ideal guide for readers from disparate areas, including analytical chemistry, materials science, nanoscience and nanotechnology, biomedical and clinical engineering, environmental science and engineering, green chemistry, and novel catalysis.
Biennial State-of-the-Art Sensors Technology in Australia 2019-2020 by Edith Chow,Rona Chandrawati Pdf
Recent developments in novel materials, sensing principles and signal processing are paving the way for new types of analytical sensors, offering improved sensing performance and practicality. Such advancements will provide accurate and real-time analytical information in the environmental, food, and healthcare sectors to better guide decision-making. For sensors to be commercially viable, the miniaturisation and integration of components for rapid, automated, in-field detection and diagnosis need to be considered. This book highlights state-of-the-art sensors technology in Australia through original contributions and reviews.
Wastewater Treatment Using Green Synthesis by Swapnila Roy,Tien Anh Tran,Zaira Zaman Chowdhury,Prathibha B.S. Pdf
Wastewater Treatment Using Green Synthesis discusses advances in wastewater treatment with a focus on biological processes. Major topics discussed include bioremediation through microorganisms, green and iron-based nanoparticles in wastewater treatment, TiO2 Doped Lignocellulosic Biopolymer with an emphasis on their photodegradation potential for a variety of pollutants, and permanent film growth. It further includes remediation of industrial sludges/effluents with a particular emphasis on biological treatment, phytoremediation, and de-ballasting water treatment technology. Features: • Focuses on the implementation of effective wastewater treatment with orientation towards biological processes • Covers both biological and physico-chemical waste and wastewater treatment processes, focusing on emerging techniques • Reviews computational method approaches, the application of TiO2-doped biopolymers, iron nanoparticles, and the use of molecular techniques for wastewater treatment • Illustrates molecular docking, molecular dynamics simulation, homology modelling, and biodegradation pathways prediction • Includes dedicated chapters on biological wastewater treatment This book is aimed at graduate students and researchers in environmental and chemical engineering with a focus on wastewater treatment.
Biomedical Nanozymes by Hui Wei,Genxi Li,Jinghong Li Pdf
This book aims to summarize the latest research progress of biomedical nanozymes in diagnostic and therapeutic related fields. In terms of diagnostics, it will cover in vitro diagnostics, live analysis, and some emerging bioanalysis. In terms of therapeutics, it will introduce antioxidant therapy, peroxidation therapy and emerging therapy respectively. Furthermore, the research results previously scattered in many journals and conferences worldwide are methodically edited and presented in a unified form. Based on the new ideas and developments presented in this book, it will be of interest to readers from different areas, such as chemistry, materials, nanoscience and nanotechnology, biomedical and clinical studies, etc.
Molecular Impacts of Nanoparticles on Plants and Algae by Huseyin Tombuloglu,Guzin Tombuloglu,Ebtesam Al-Suhaimi,Abdulhadi Baykal,Khalid Rehman Hakeem Pdf
Molecular Impacts of Nanoparticles on Plants and Algae covers molecular mechanisms of plants/algae related to cellular uptake and translocation of nanoparticles, and genome, transcriptome, proteome, and metabolome responses against it. The book introduces readers to state-of-the-art developments and trends of nanoparticles and plants/algae including interaction of nanoparticles with biological compounds in vitro. Nanoscience and nanotechnology have rapidly been developed in the last few decades, and they have a wide range of applications in industry, medicine, food, and agriculture. In agriculture, nanoparticles (NPs) have successfully been used for growth regulation, crop protection and improvement. They are also employed to cope with plant nutrient deficiencies. A predicted significant increase in the output of NPs will cause the discharge of a remarkable number of NPs to ecosystems, creating a need to understand how to optimize or mitigate their impact depending on their potential impact. These include serious health concerns for living organisms in aquatic, terrestrial, and atmospheric environments as well as human health through their potential existence in plant-based foods. The impact of NPs on living organisms including plants and algae, and uptake, translocation and molecular response mechanisms should be carefully considered before producing and using nanoparticles in large amounts as NPs, when entered to the body, induce changes in gene expressions related to the photosystem, water transport, cell wall formation, and cell division. Further recent studies have showed that NPs are potential agents or stressors to alter proteome, transcriptome, genome and metabolome responses. Impacts of nanoparticles on molecular mechanisms of plants and algae presents the most recent findings on nanoparticle and plant/algae interaction by focusing to molecular response mechanisms at genome, transcriptome, proteome and metabolome levels. In addition, uptake and translocation mechanism of nanoparticles will be assessed both in plant and algae Throughout this book, the latest developments and discoveries will be highlighted as well as open problems and future challenges in molecular mechanisms of plants/algae as a response of nanoparticles. Presents genome, transcriptome, proteome, and metabolome responses in plants/algae, along with cellular uptake and translocation mechanisms Illustrates nano-particle-plant/algae interactions Covers both simple and higher organisms, addressing both algae and plant
Harnessing NanoOmics and Nanozymes for Sustainable Agriculture by Rajput, Vishnu D.,Singh, Abhishek,Ghazaryan, Karen,Alexiou, Athanasios,Said Al-Tawaha, Abdel Rahman Mohammad Pdf
In an era overshadowed by pressing global challenges such as climate change, burgeoning populations, and the depletion of natural resources, the agricultural landscape is at a critical juncture. The need for sustainable practices has never been more urgent, with conventional methods struggling to meet the demands of a growing population while grappling with environmental degradation. Harnessing NanoOmics and Nanozymes for Sustainable Agriculture delves into the heart of the problem, navigating the intricate web of challenges facing agriculture today. From dwindling crop yields to the environmental repercussions of conventional farming practices, the urgency to find innovative, sustainable solutions is paramount. Harnessing NanoOmics and Nanozymes for Sustainable Agriculture offers a comprehensive exploration of nanotechnology's potential to revolutionize agriculture, presenting a promising pathway toward enhanced productivity, minimizing environmental impact, and optimal resource utilization.
Nanozymes in Medicine by Hemant Kumar Daima,Navya PN,Eric Lichtfouse Pdf
This book reviews the latest advances and biomedical applications of nanozymes, which are artificial nanomaterials exhibiting enzymatic properties similar to natural enzymes, but with less limitations than natural enzymes. Nanozymes display advantages such as facile synthesis, easy surface modification, improved stability, higher catalytic power, and target-specific binding. Nanozymes containing metals, metal oxides, carbon, and metal sulfide are actually used for cancer therapy, biomolecules sensing, bioimaging, disease diagnostics and diabetes management. The book discloses underlying mechanisms, concepts, recent trends, constraints, and prospects for nanomedicine using nanozymes.
Iron Oxide-Based Nanocomposites and Nanoenzymes by Harekrushna Sahoo,Jitendra Kumar Sahoo Pdf
This contributed volume provides a comprehensive understanding of synthetic protocols, characterization techniques, and current applications of iron oxide-based nanocomposite and nanoenzyme materials. It covers basic concepts and recent advancements in iron oxide-based nanocomposites and nanoenzymes, focusing on their synthesis, characterization, and functionalization for specific research applications. The different chapters in the book highlight key characterization techniques including Fourier Transform Infrared Spectroscopy, X-ray diffraction, Scanning Electron Microscopy, and Transmission Electron Microscopy, among others while it also explores various applications of these materials, such as adsorption of heavy metals and dyes, gas sensors, biomedical applications, photo-catalysis, and photovoltaic sensors. This book serves as a valuable resource for researchers and graduate students working in the fields of materials science, chemistry, physics, and biotechnology.
Nanozymes for Environmental Engineering by Hemant Kumar Daima,Navya PN,Eric Lichtfouse Pdf
This book reviews the latest developments and applications of nanozymes in environmental science. Protection of the environment is essential because pollution has become a global problem with many adverse effects on life and ecosystems. For that, remediation strategies and techniques have been designed, yet they are limited. Here, the recent development of nanotechnology opens a new vista for environmental remediation. In particular, nanomaterials displaying enzyme-like activities, named ‘nanozymes’, appear very promising for environmental monitoring, contaminant detection, microbial management, and degradation of organic pollutants. Nanomaterials including metallic, metal oxides and carbon-based nanoparticles with nanozymes activities have been synthesized. These nanozymes have similar activities as natural peroxidase, oxidase, superoxide dismutase and catalase enzymes. Nanozymes have several advantages, yet they suffer from several limitations such as low catalytic efficiency, less substrate selectivity, biocompatibility, and lack of engineering of the active sites.
Biosensors – Recent Advances and Future Challenges by Paolo Bollella,Evgeny Katz Pdf
The present book is devoted to all aspects of biosensing in a very broad definition, including, but not limited to, biomolecular composition used in biosensors (e.g., biocatalytic enzymes, DNAzymes, abiotic nanospecies with biocatalytic features, bioreceptors, DNA/RNA, aptasensors, etc.), physical signal transduction mechanisms (e.g., electrochemical, optical, magnetic, etc.), engineering of different biosensing platforms, operation of biosensors in vitro and in vivo (implantable or wearable devices), self-powered biosensors, etc. The biosensors can be represented with analogue devices measuring concentrations of analytes and binary devices operating in the YES/NO format, possibly with logical processing of input signals. Furthermore, the book is aimed at attracting young scientists and introducing them to the field, while providing newcomers with an enormous collection of literature references.
Integrated Omics Approaches to Infectious Diseases by Saif Hameed,Zeeshan Fatima Pdf
This book examines applications of multi-omics approaches for understanding disease etiology, pathogenesis, host-pathogen interactions. It also analyzes the genetics, immunological and metabolic mechanisms underlying the infections. The book also explores genomics, transcriptomics, translational-omics, and metabolomics approaches to understand the pathogenesis and identify potential drug targets. It reviews the role of epigenetic reprogramming in shaping the host-pathogen interactions and presents bioinformatics application in the identification of drug targets. Further, it examines the potential applications of RNA sequencing and non-coding RNA profiling to identify the pathogenesis. Lastly, it offers the current challenges, technological advances, and prospects of using multi-omics technologies in infectious biology.