Neonatal And Pediatric Pharmacology

Author : Sumner J. Yaffe,Jacob V. Aranda
Publisher : Lippincott Williams & Wilkins
Page : 1072 pages
File Size : 53,6 Mb
Release : 2011
Category : Medical
ISBN : 9780781795388

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Neonatal and Pediatric Pharmacology by Sumner J. Yaffe,Jacob V. Aranda Pdf

"Neonatal and Pediatric Pharmacology offers guidelines for safe, effective, and rational drug therapy in newborns, children and adolescents. The book provides relevant and useful data on the molecular, physiologic, biochemical, and pharmacologic mechanisms of drug action and therapy in this population. The authors identify areas of innovative basic and translational research necessary for the continuing evaluation and development of drugs for the fetus, newborns, children and adolescents. Neonatal and Pediatric Pharmacology is is a valuable reference for all health care professionals who treat the fetus, newborns, children, and adolescents, including neonatologists, nurses, pediatricians, general practitioners, students, obstetricians, perinatologists, surgeons and allied health professionals. It will be useful anytime during the day and especially in the middle of the night when knowledge of appropriate indications, safe and effective use, dosage, and therapeutic regimen for a certain drug or molecular entity is immediately needed. The book is also directed to those involved in basic, clinical, and other academic pharmacological research, the pharmaceutical industry, and regulatory agencies dealing with drug and therapeutic developments for this population. Those teaching pharmacology and therapeutics will find this compilation of information extremely useful in preparing teaching materials"--Provided by publisher.

Author : Jacob V. Aranda
Publisher : Lippincott Williams & Wilkins
Page : 2499 pages
File Size : 55,5 Mb
Release : 2020-11-05
Category : Medical
ISBN : 9781975112493

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Yaffe and Aranda's Neonatal and Pediatric Pharmacology by Jacob V. Aranda Pdf

The premier comprehensive textbook in the field, Yaffe and Aranda’s Neonatal and Pediatric Pharmacology, Fifth Edition, provides an authoritative overview of all aspects of drug therapy in newborns, children, and adolescents. It offers evidence-based guidelines for safe, effective, and rational drug therapy, including specific recommendations for all major drug classes and diseases. Now in a vibrant two-color format, this fully revised reference is an indispensable resource for pediatricians, neonatologists, pediatric residents, and fellows in different pediatric subspecialties, including neonatal medicine and pediatric critical care.

Author : Sumner J. Yaffe,Jacob V Aranda,Yaffe
Publisher : Lww
Page : 1066 pages
File Size : 42,7 Mb
Release : 2015-04-24
Category : Electronic
ISBN : 1469875489

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Neonatal and Pediatric Pharmacology by Sumner J. Yaffe,Jacob V Aranda,Yaffe Pdf

Written by experts at the forefront of current research and clinical practice, this volume provides evidence-based guidelines for safe, effective, and rational drug therapy in newborns, children, and adolescents. Includes updated information on drug interactions and regulatory issues.

Author : John N van den Anker,Max J. Coppes,Gideon Koren
Publisher : Elsevier Health Sciences
Page : 240 pages
File Size : 48,6 Mb
Release : 2012-10-30
Category : Medical
ISBN : 9781455747382

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Neonatal and Pediatric Clinical Pharmacology, An Issue of Pediatric Clinics - E-Book by John N van den Anker,Max J. Coppes,Gideon Koren Pdf

The need for safe and effective use of medicines in children and WHO's initiative "Make Medicines Child Size" have boosted research and educational activities in the area of pediatric clinical drug research. This issue focuses on both general and specific aspects of neonatal and pediatric clinical pharmacology including ethics, pharmacogenomics, metabolomics, adverse drug reactions, pain medication, pulmonary hypertension and several other hot topics. The editors have been able to find outstanding authors for the different parts on neonatal and pediatric pharmacology.

Author : F.B. Mimouni,J.N. van den Anker
Publisher : Karger Medical and Scientific Publishers
Page : 136 pages
File Size : 43,6 Mb
Release : 2014-11-17
Category : Medical
ISBN : 9783318027365

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Neonatal Pharmacology and Nutrition Update by F.B. Mimouni,J.N. van den Anker Pdf

In order to provide safe and effective drug therapy to neonates, it is necessary to know about and understand the impact their development has on the pharmacokinetics and pharmacodynamics of drugs. The fact that children are different and neonates very different from adults means that, in neonates, it would be unwise to dose medications by scaling down adult doses proportionately, simply attempting to match their smaller weight and/or body surface area. When one makes decisions about neonatal drug therapy, one must not only take into consideration the available data but also critically assess and interpret this information within the context of fetal development and maturational processes as well as within the context of diseases that might affect a drug’s biodisposition. This book includes the latest information on the regulation and scientific basis of drug development and also provides a rationale for formula development for preterm infants. It offers guidance on how to translate pharmacokinetic data into dosing recommendations and also covers legal and regulatory issues relating to neonatal pharmacotherapy.

Author : George Rylance,David R. Harvey,Jacob V. Aranda
Publisher : Elsevier
Page : 302 pages
File Size : 55,6 Mb
Release : 2013-10-22
Category : Medical
ISBN : 9781483163000

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Neonatal Clinical Pharmacology and Therapeutics by George Rylance,David R. Harvey,Jacob V. Aranda Pdf

Neonatal Clinical Pharmacology and Therapeutics covers the significant advances in clinical pharmacology and the principles of neonatal therapeutics. This book is composed of 20 chapters that tackle various neonatal diseases and their corresponding therapeutic options. The opening chapters review the pharmacological principles and kinetics, placental drug transfer, and drug therapy in pregnancy. The next chapters consider the other aspects of clinical pharmacology, including tocolytics, oxytocin, maternal drug use, neonatal withdrawal, prophylaxis, and the effect of material analgesia and anesthetics on newborn. Considerable chapters are devoted to the treatment options of neonatal diseases, including apnea, pulmonary and systemic disorders, cardiac diseases, jaundice, hypoglycemia, and nutrient deficiencies. The remaining chapters discuss other therapeutic options, such as blood cell component therapy, the use of analgesia and muscle relaxants, and parenteral nutrition. This book is intended primarily for all doctors who care for newborn babies and clinical pharmacologists.

Author : Carole Kenner,Judy Lott
Publisher : Springer Publishing Company
Page : 1023 pages
File Size : 45,5 Mb
Release : 2013-08-21
Category : Medical
ISBN : 9780826109750

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Comprehensive Neonatal Nursing Care by Carole Kenner,Judy Lott Pdf

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Author : Jacob V. Aranda
Publisher : Elsevier Health Sciences
Page : 128 pages
File Size : 42,6 Mb
Release : 2017-12-01
Category : Medical
ISBN : 9780323552912

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Pediatric Pharmacology and Drug Therapy, An Issue of Pediatric Clinics of North America, E-Book by Jacob V. Aranda Pdf

Dr. Aranda is an top expert in the area of pharmacology in the pediatric population. His issue has knowledgeable authors presenting clinical reviews on a wide variety of topics, from "hot areas " of drug therapy to drug abuse in children as well as current areas of debate in neonatal drug therapy. Articles are devoted to the following topics: New and Current Drug Therapies For Asthma In Children; Psychopharmacology Of Bipolar Disorders in Children and Adolescents; Designer Drug Abuse in School Children; Dietary Supplements in Children; Anticoagulant Therapies in Children; New Antimicrobials for Gram-Positive Infections in Children; Probiotics in Newborns And Children; Anticonvulsant Therapies in Newborns and Children; Immunomodulator Drug Therapies in Inflammatory Bowel Diseases in Children; Non-Steroidal Anti-Inflammatory Drugs in Newborns and Children; Metformin Use in Pre-Diabetic Children and Adolescents; Problems in Drug Dosing of Obese Children; Inhaled Drugs and Systemic Steroids for Bronchopulmonary Dysplasia; Antifungal Drugs in Newborns and Children; Antiviral Drugs In Newborns and Children; and Development of Drug Therapies for Newborns and Children. Readers will come away with the latest clinical information to help inform them when diagnosing and prescribing for children.

Author : Hannsjörg W. Seyberth,Anders Rane,Matthias Schwab
Publisher : Springer Science & Business Media
Page : 385 pages
File Size : 53,6 Mb
Release : 2011-09-01
Category : Medical
ISBN : 9783642201950

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Pediatric Clinical Pharmacology by Hannsjörg W. Seyberth,Anders Rane,Matthias Schwab Pdf

The objective of this volume is to give an overview of the present state of the art of pediatric clinical pharmacology including developmental physiology, pediatric-specific pathology, special tools and methods for development of drugs for children (assessment of efficacy, toxicity, long-term safety etc.) as well as regulatory and ethical knowledge and skills. In the future, structural and educational changes have to lead back to a closer cooperation and interaction of pediatrics with (clinical) pharmacology and pharmacy.

Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Pediatric Studies Conducted Under the Best Pharmaceuticals for Children Act (BPCA) and the Pediatric Research Equity Act (PREA)
Publisher : National Academies Press
Page : 432 pages
File Size : 50,8 Mb
Release : 2012-10-13
Category : Medical
ISBN : 9780309225496

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Safe and Effective Medicines for Children by Institute of Medicine,Board on Health Sciences Policy,Committee on Pediatric Studies Conducted Under the Best Pharmaceuticals for Children Act (BPCA) and the Pediatric Research Equity Act (PREA) Pdf

The Best Pharmaceuticals for Children Act (BPCA) and the Pediatric Research Equity Act (PREA) were designed to encourage more pediatric studies of drugs used for children. The FDA asked the IOM to review aspects of pediatric studies and changes in product labeling that resulted from BPCA and PREA and their predecessor policies, as well as assess the incentives for pediatric studies of biologics and the extent to which biologics have been studied in children. The IOM committee concludes that these policies have helped provide clinicians who care for children with better information about the efficacy, safety, and appropriate prescribing of drugs. The IOM suggests that more can be done to increase knowledge about drugs used by children and thereby improve the clinical care, health, and well-being of the nation's children.

Author : Sumner J. Yaffe
Publisher : Unknown
Page : 696 pages
File Size : 40,9 Mb
Release : 1992
Category : Medical
ISBN : UOM:39015024910005

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Pediatric Pharmacology by Sumner J. Yaffe Pdf

Covers the general principles of pediatric pharmacology from a clinical perspective. Over 80 distinguished authorities discuss drugs and pregnancy, with special emphasis on maternal-fetal medicine, drugs and the infant, child, and adolescent, as well as specific drugs and adverse drug effects.

Author : Ravi D. Shah,Santhanam Suresh
Publisher : Springer Nature
Page : 355 pages
File Size : 46,6 Mb
Release : 2020-02-21
Category : Medical
ISBN : 9783030362874

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Opioid Therapy in Infants, Children, and Adolescents by Ravi D. Shah,Santhanam Suresh Pdf

Opioid analgesics are among the most effective medications for pain management but are associated with serious and increasing public health problems, including abuse, addiction, and death from overdose. Currently, there is an opioid epidemic in the United States with the rate of prescription opioid-related overdose deaths quadrupling over the last 15 years. Pediatric patients are particularly vulnerable to the devastating consequences of opioid misuse. Adolescents who are prescribed opioids are at a higher risk for abusing illicit drugs later in life. Clinicians managing pediatric pain must account for such issues while still delivering effective analgesia to young patients who suffer from both acute and chronic pain. Opioid Therapy in Children and Adolescents is designed to explore the unique aspects of opioid therapy in pediatric patients. An introductory framework provides historical context and describes the epidemiology of the opioid crisis with focus on pediatric implications. Subsequent chapters focus on pediatric opioid pharmacology, safe opioid prescribing practices, and non-opioid alternatives to managing pediatric pain states, including multimodal analgesic strategies, interdisciplinary approaches, and complementary medicine. Mitigation strategies against pediatric opioid diversion and misuse are addressed to help clinicians develop practice changes that protect pediatric patients from opioid-related morbidity and mortality. Clinical case examples are also utilized throughout the text to provide grounding for each chapter and a context within which to examine pertinent issues. This first of its kind book provides a comprehensive approach that will guide clinicians to appropriately and safely prescribe opioid analgesics to pediatric patients suffering from pain. It is an invaluable resource for pediatricians, family practitioners, anesthesiologists, pediatric oncologists, and other clinicians who manage pediatric pain.

Author : Carol K. Taketomo,Jane Hurlburt Hodding,Donna M. Kraus
Publisher : Unknown
Page : 0 pages
File Size : 41,6 Mb
Release : 2009
Category : Chemotherapy
ISBN : 1591952689

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Pediatric Dosage Handbook with International Trade Names Index by Carol K. Taketomo,Jane Hurlburt Hodding,Donna M. Kraus Pdf

Lexi-Comp's Pediatric Dosage Handbook with International Trade Names Index, 16th Edition, continues as the most trusted dosing reference for neonates, infants, and children. This practical guide includes an alphabetical drug section, a comprehensive appendix of comparative charts, tables, and supporting information, a therapeutic category and key word index, and an international index with trade names from over 100 countries. With this edition, the handbook employs a new size and two-column format, making it easier than ever to use. Drug monographs provide up to 39 fields of pharmacology detail, including neonatal dosing, drug administration, and extemporaneous preparations. Other fields of interest include warnings, precautions, adverse reactions, drug interactions, patient information and more. The Pediatric Dosage Handbook with International Trade Names Index is the ideal point-of-care resource for medical professionals managing pediatric patients. 855 Drug Monographs Over 100 Extemporaneous Preparation Recipes Over 300 Pages of Appendix Information Book jacket.

Author : Karin E. Zenk,Jack H. Sills,Robin M. Koeppel
Publisher : NICU Ink Book Publishers
Page : 792 pages
File Size : 50,6 Mb
Release : 2000
Category : Chemotherapy
ISBN : UOM:39015045484329

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Neonatal Medications & Nutrition by Karin E. Zenk,Jack H. Sills,Robin M. Koeppel Pdf

Author : Andrew E. Mulberg,Dianne Murphy,Julia Dunne,Lisa L. Mathis
Publisher : John Wiley & Sons
Page : 782 pages
File Size : 53,8 Mb
Release : 2013-05-20
Category : Medical
ISBN : 9781118312056

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Pediatric Drug Development by Andrew E. Mulberg,Dianne Murphy,Julia Dunne,Lisa L. Mathis Pdf

Most medicines have never been adequately tested for safety and efficacy in pediatric populations and preterm, infants and children are particularly vulnerable to adverse drug reactions. Pediatric Drug Development: Concepts and Applications, Second Edition, addresses the unique challenges in conducting effective drug research and development in pediatric populations. This new edition covers the legal and ethical issues of consent and assent, the additional legal and safety protections for children, and the appropriate methods of surveillance and assessment for children of varying ages and maturity, particularly for patient reported outcomes. It includes new developments in biomarkers and surrogate endpoints, developmental pharmacology and other novel aspects of global pediatric drug development. It also encompasses the new regulatory initiatives across EU, US and ROW designed to encourage improved access to safe and effective medicines for children globally. From an international team of expert contributors Pediatric Drug Development: Concepts and Applications is the practical guide to all aspects of the research and development of safe and effective medicines for children.