Network Biology

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Networks of Networks in Biology

Author : Narsis A. Kiani,David Gomez-Cabrero,Ginestra Bianconi
Publisher : Cambridge University Press
Page : 215 pages
File Size : 53,5 Mb
Release : 2021-04
Category : Computers
ISBN : 9781108428873

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Networks of Networks in Biology by Narsis A. Kiani,David Gomez-Cabrero,Ginestra Bianconi Pdf

Introduces network inspired approaches for the analysis and integration of large, heterogeneous data sets in the life sciences.

Network Biology

Author : Gerard Cagney,Andrew Emili
Publisher : Humana Press
Page : 0 pages
File Size : 54,9 Mb
Release : 2011-09-28
Category : Science
ISBN : 1617792756

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Network Biology by Gerard Cagney,Andrew Emili Pdf

While extremely large datasets describing gene sequences, mRNA transcripts, protein abundance, and metabolite concentrations are increasingly commonplace, these represent only starting ‘parts lists’ that are usually insufficient to unlock mechanistic insights on their own right. Fortunately, as Network Biology: Methods and Applications examines, concepts emerging from the study of biological entities such as networks (e.g. functional interactions linking genes, proteins, metabolites, etc.) suggest that order rather than chaos prevails, with such principles as modular and hierarchical organization, reactive information-driven causal-response behaviours, systems robustness, co-evolution, and self-organization guiding the way. This volume presents detailed, practical descriptions of the experimental and computational approaches currently prevalent in network biology as written by practiced experts in the field. Written in the highly successful Methods in Molecular BiologyTM series format, relevant chapters contain introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and accessible, Network Biology: Methods and Applications provides an ensemble of procedures that will be of great value to a broad assortment of readers, ranging from graduate students to seasoned professionals looking to polish their skill sets.

Fundamentals Of Network Biology

Author : Zhang Wenjun
Publisher : World Scientific
Page : 568 pages
File Size : 47,6 Mb
Release : 2018-05-16
Category : Science
ISBN : 9781786345103

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Fundamentals Of Network Biology by Zhang Wenjun Pdf

As the first comprehensive title on network biology, this book covers a wide range of subjects including scientific fundamentals (graphs, networks, etc) of network biology, construction and analysis of biological networks, methods for identifying crucial nodes in biological networks, link prediction, flow analysis, network dynamics, evolution, simulation and control, ecological networks, social networks, molecular and cellular networks, network pharmacology and network toxicology, big data analytics, and more. Across 12 parts and 26 chapters, with Matlab codes provided for most models and algorithms, this self-contained title provides an in-depth and complete insight on network biology. It is a valuable read for high-level undergraduates and postgraduates in the areas of biology, ecology, environmental sciences, medical science, computational science, applied mathematics, and social science. Contents: Mathematical Fundamentals: Fundamentals of Graph TheoryGraph AlgorithmsFundamentals of Network TheoryOther FundamentalsCrucial Nodes/Subnetworks/Modules, Network Types, and Structural Comparison: Identification of Crucial Nodes and Subnetworks/ModulesDetection of Network TypesComparison of Network StructureNetwork Dynamics, Evolution, Simulation and Control: Network DynamicsNetwork Robustness and Sensitivity AnalysisNetwork ControlNetwork EvolutionCellular AutomataSelf-OrganizationAgent-based ModelingFlow Analysis: Flow/Flux AnalysisLink and Node Prediction: Link Prediction: Sampling-based MethodsLink Prediction: Structure- and Perturbation-based MethodsLink Prediction: Node-Similarity-based MethodsNode PredictionNetwork Construction: Construction of Biological NetworksPharmacological and Toxicological Networks: Network Pharmacology and ToxicologyEcological Networks: Food WebsMicroscopic Networks: Molecular and Cellular NetworksSocial Networks: Social Network AnalysisSoftware: Software for Network AnalysisBig Data Analytics: Big Data Analytics for Network Biology Readership: Advanced undergraduates and graduate students and researchers in biology, ecology, pharmacology, applied mathematics, computational science, etc. Keywords: Network Biology;Network Analysis;Food Webs;Molecular Networks;Social Networks;Network Pharmacology;Link Prediction;Network Dynamics;Big Data Analytics;Software;Models;Algorithms;Nodes;LinksReview:0

Weighted Network Analysis

Author : Steve Horvath
Publisher : Springer Science & Business Media
Page : 433 pages
File Size : 43,6 Mb
Release : 2011-04-30
Category : Science
ISBN : 9781441988195

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Weighted Network Analysis by Steve Horvath Pdf

High-throughput measurements of gene expression and genetic marker data facilitate systems biologic and systems genetic data analysis strategies. Gene co-expression networks have been used to study a variety of biological systems, bridging the gap from individual genes to biologically or clinically important emergent phenotypes.

Biological Network Analysis

Author : Pietro Hiram Guzzi,Swarup Roy
Publisher : Elsevier
Page : 212 pages
File Size : 42,7 Mb
Release : 2020-05-11
Category : Science
ISBN : 9780128193518

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Biological Network Analysis by Pietro Hiram Guzzi,Swarup Roy Pdf

Biological Network Analysis: Trends, Approaches, Graph Theory, and Algorithms considers three major biological networks, including Gene Regulatory Networks (GRN), Protein-Protein Interaction Networks (PPIN), and Human Brain Connectomes. The book's authors discuss various graph theoretic and data analytics approaches used to analyze these networks with respect to available tools, technologies, standards, algorithms and databases for generating, representing and analyzing graphical data. As a wide variety of algorithms have been developed to analyze and compare networks, this book is a timely resource. Presents recent advances in biological network analysis, combining Graph Theory, Graph Analysis, and various network models Discusses three major biological networks, including Gene Regulatory Networks (GRN), Protein-Protein Interaction Networks (PPIN) and Human Brain Connectomes Includes a discussion of various graph theoretic and data analytics approaches

Networks in Cell Biology

Author : Mark Buchanan,Guido Caldarelli,Paolo De Los Rios,Francesco Rao,Michele Vendruscolo
Publisher : Cambridge University Press
Page : 282 pages
File Size : 40,9 Mb
Release : 2010-05-13
Category : Science
ISBN : 9780521882736

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Networks in Cell Biology by Mark Buchanan,Guido Caldarelli,Paolo De Los Rios,Francesco Rao,Michele Vendruscolo Pdf

Key introductory text for graduate students and researchers in physics, biology and biochemistry.

Introduction to Biological Networks

Author : Alpan Raval,Animesh Ray
Publisher : CRC Press
Page : 329 pages
File Size : 41,8 Mb
Release : 2016-04-19
Category : Computers
ISBN : 9781420010367

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Introduction to Biological Networks by Alpan Raval,Animesh Ray Pdf

The new research area of genomics-inspired network biology lacks an introductory book that enables both physical/computational scientists and biologists to obtain a general yet sufficiently rigorous perspective of current thinking. Filling this gap, Introduction to Biological Networks provides a thorough introduction to genomics-inspired network bi

Analyzing Network Data in Biology and Medicine

Author : Nataša Pržulj
Publisher : Cambridge University Press
Page : 647 pages
File Size : 49,5 Mb
Release : 2019-03-28
Category : Language Arts & Disciplines
ISBN : 9781108432238

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Analyzing Network Data in Biology and Medicine by Nataša Pržulj Pdf

Introduces biological concepts and biotechnologies producing the data, graph and network theory, cluster analysis and machine learning, using real-world biological and medical examples.

Network Biology

Author : Intawat Nookaew
Publisher : Springer
Page : 202 pages
File Size : 48,7 Mb
Release : 2017-05-03
Category : Science
ISBN : 9783319564609

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Network Biology by Intawat Nookaew Pdf

This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science. Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.

Applied Statistics for Network Biology

Author : Matthias Dehmer,Frank Emmert-Streib,Armin Graber,Armindo Salvador
Publisher : John Wiley & Sons
Page : 441 pages
File Size : 48,6 Mb
Release : 2011-04-08
Category : Medical
ISBN : 9783527638086

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Applied Statistics for Network Biology by Matthias Dehmer,Frank Emmert-Streib,Armin Graber,Armindo Salvador Pdf

The book introduces to the reader a number of cutting edge statistical methods which can e used for the analysis of genomic, proteomic and metabolomic data sets. In particular in the field of systems biology, researchers are trying to analyze as many data as possible in a given biological system (such as a cell or an organ). The appropriate statistical evaluation of these large scale data is critical for the correct interpretation and different experimental approaches require different approaches for the statistical analysis of these data. This book is written by biostatisticians and mathematicians but aimed as a valuable guide for the experimental researcher as well computational biologists who often lack an appropriate background in statistical analysis.

Computational Modeling of Genetic and Biochemical Networks

Author : James M. Bower,Hamid Bolouri
Publisher : MIT Press
Page : 386 pages
File Size : 51,5 Mb
Release : 2001
Category : Computers
ISBN : 0262524236

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Computational Modeling of Genetic and Biochemical Networks by James M. Bower,Hamid Bolouri Pdf

How new modeling techniques can be used to explore functionally relevant molecular and cellular relationships.

Systems Biology for Signaling Networks

Author : Sangdun Choi
Publisher : Springer Science & Business Media
Page : 900 pages
File Size : 52,5 Mb
Release : 2010-08-09
Category : Science
ISBN : 9781441957979

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Systems Biology for Signaling Networks by Sangdun Choi Pdf

System Biology encompasses the knowledge from diverse fields such as Molecular Biology, Immunology, Genetics, Computational Biology, Mathematical Biology, etc. not only to address key questions that are not answerable by individual fields alone, but also to help in our understanding of the complexities of biological systems. Whole genome expression studies have provided us the means of studying the expression of thousands of genes under a particular condition and this technique had been widely used to find out the role of key macromolecules that are involved in biological signaling pathways. However, making sense of the underlying complexity is only possible if we interconnect various signaling pathways into human and computer readable network maps. These maps can then be used to classify and study individual components involved in a particular phenomenon. Apart from transcriptomics, several individual gene studies have resulted in adding to our knowledge of key components that are involved in a signaling pathway. It therefore becomes imperative to take into account of these studies also, while constructing our network maps to highlight the interconnectedness of the entire signaling pathways and the role of that particular individual protein in the pathway. This collection of articles will contain a collection of pioneering work done by scientists working in regulatory signaling networks and the use of large scale gene expression and omics data. The distinctive features of this book would be: Act a single source of information to understand the various components of different signaling network (roadmap of biochemical pathways, the nature of a molecule of interest in a particular pathway, etc.), Serve as a platform to highlight the key findings in this highly volatile and evolving field, and Provide answers to various techniques both related to microarray and cell signaling to the readers.

Analysis of Complex Networks

Author : Matthias Dehmer,Frank Emmert-Streib
Publisher : John Wiley & Sons
Page : 480 pages
File Size : 47,9 Mb
Release : 2009-07-10
Category : Medical
ISBN : 9783527627998

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Analysis of Complex Networks by Matthias Dehmer,Frank Emmert-Streib Pdf

Mathematical problems such as graph theory problems are of increasing importance for the analysis of modelling data in biomedical research such as in systems biology, neuronal network modelling etc. This book follows a new approach of including graph theory from a mathematical perspective with specific applications of graph theory in biomedical and computational sciences. The book is written by renowned experts in the field and offers valuable background information for a wide audience.

Integrative Genomics and Network Biology in Livestock and other Domestic Animals

Author : David E. MacHugh,Robert J. Schaefer
Publisher : Frontiers Media SA
Page : 450 pages
File Size : 44,7 Mb
Release : 2020-09-11
Category : Medical
ISBN : 9782889639991

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Integrative Genomics and Network Biology in Livestock and other Domestic Animals by David E. MacHugh,Robert J. Schaefer Pdf

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

An Introduction to Systems Biology

Author : Uri Alon
Publisher : CRC Press
Page : 324 pages
File Size : 43,5 Mb
Release : 2006-07-07
Category : Mathematics
ISBN : 9781584886426

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An Introduction to Systems Biology by Uri Alon Pdf

Thorough and accessible, this book presents the design principles of biological systems, and highlights the recurring circuit elements that make up biological networks. It provides a simple mathematical framework which can be used to understand and even design biological circuits. The textavoids specialist terms, focusing instead on several well-studied biological systems that concisely demonstrate key principles. An Introduction to Systems Biology: Design Principles of Biological Circuits builds a solid foundation for the intuitive understanding of general principles. It encourages the reader to ask why a system is designed in a particular way and then proceeds to answer with simplified models.