Neurophysiology Of The Migraine Brain

Author : Gianluca Coppola,Wei-Ta Chen
Publisher : Springer Nature
Page : 236 pages
File Size : 54,6 Mb
Release : 2020-10-20
Category : Medical
ISBN : 9783030565381

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Neurophysiology of the Migraine Brain by Gianluca Coppola,Wei-Ta Chen Pdf

Roughly one in every five patients referred to a neurologist suffers from headaches; the majority have migraines. Although headache specialists understand migraine on a clinical basis, the pathophysiological changes that provoke and accompany the development of a migraine attack continue to elude us. Several decades have passed since the pioneering electroencephalographic study by Golla and Winter (1959), which underscored the role of abnormal rhythmic activities in migraine. Since then, there have been substantial advances in the field; a wealth of neurophysiological studies has enriched our understanding of the pathophysiological facets of the migraine pathology. Virtually every known technique of clinical electrophysiology has since been used to study the migraine brain and, more recently, new neurophysiological tools have been added to the arsenal. Nevertheless, applying the principles of peripheral and central neuromodulation offers a promising way to transfer the principles of synaptic plasticity to the patient’s bedside. This book belongs to the Headache Series endorsed by the European Headache Federation. Written by internationally recognized experts in their respective fields, it covers all aspects of clinical neurophysiological methods that represent significant advances in our understanding of the pathophysiology of migraine. It will offer a valuable toolkit for beginners, and a reference guide for experts.

Author : David Borsook
Publisher : Oxford University Press, USA
Page : 400 pages
File Size : 42,8 Mb
Release : 2012-07-26
Category : Health & Fitness
ISBN : 9780199754564

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The Migraine Brain by David Borsook Pdf

The Migraine Brain provides a general overview of the history of migraine, its pathophysiology, as well as in-depth details on the Clinical Perspectives and the different imaging techniques in use (MR, fMRI, DTI, VBM, PET, fMRI, and MEG). It also includes details on modulation of the brain using such techniques as TMS. The book concludes with a discussion of future uses of imaging in the diagnosis and treatment of migraines and other headaches.

Author : Turgay Dalkara,Michael A. Moskowitz
Publisher : John Wiley & Sons
Page : 424 pages
File Size : 50,9 Mb
Release : 2017-06-08
Category : Medical
ISBN : 9781118967218

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Neurobiological Basis of Migraine by Turgay Dalkara,Michael A. Moskowitz Pdf

Published with the New York Academy of Sciences A timely, broad-ranging exploration of the neurobiological basis and molecular mechanisms of migraines Migraines impact the lives of a significant portion of the world's population, afflicting sufferers with severe pain, nausea, and often visual impairment. The WHO views migraines as an important public health issue, and ranks them in its top twenty most disabling illnesses. Neurobiological Basis of Migraine reviews the latest advances made in our understanding of the primary basic mechanisms of migraine headache and provides valuable insights into how these findings are being translated into novel treatment and prevention strategies around the world. Written for researchers and clinicians alike, the book features edited contributions from distinguished experts in the field, taking a focused, yet wide-ranging approach to the subject. It begins by exploring the pathways and networks mediating migraine headaches, their underlying physiological mechanisms, characteristics of visceral pain, and the concept of dural neurogenic inflammation. From there the authors delve into the mechanisms sustaining the head pain and photophobia associated with migraines, and they review the pharmacology of newly discovered migraine treatments. These basic chapters are followed by clinical and genetic studies linking to key issues, including cortical spreading depression, ion channels, transporters, and epilepsy. Reviews of the latest advances in our understanding of the neurobiological basis of migraine Translates important research findings from around the globe into novel treatments strategies currently being investigated Provides researchers and clinicians with a deep understanding of the primary mechanisms of migraine from migraine modeling to clinical applications Includes contributions by many of the most respected researchers in the field, world-wide Discusses exciting recent developments in migraine mutations and their role in CSD, as well as the role of CSD in aura and trigeminal activation Timely, comprehensive, and authoritative, Neurobiological Basis of Migraine is an indispensable working resource for clinicians and migraine, headache, and pain researchers, including neurobiologists, neuropharmacologists, neurologists, and vascular neurobiologists, as well as graduate students in those fields who are involved in researching migraine headaches.

Author : Carolyn Bernstein,Elaine McArdle
Publisher : Simon and Schuster
Page : 347 pages
File Size : 53,7 Mb
Release : 2008-09-16
Category : Health & Fitness
ISBN : 9781416580331

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The Migraine Brain by Carolyn Bernstein,Elaine McArdle Pdf

A comprehensive book that explains how to cope with migraines by an esteemed neurologist. You know that your migraine isn't just a headache. But you may not know that migraine actually is a neurological disease. Affecting one in five women, one in twenty men, and one in twenty children, it's a debilitating, complex, and chronic condition that manifests in a combination of symptoms that can include excruciating head pain as well as other distinctive physical and emotional effects. Yet it's also a disease that you can get control of, improve, and manage, as Dr. Carolyn Bernstein has discovered in her seventeen years as a Harvard Medical School faculty member and practicing neurologist. Praised for her excellence and compassion, the founder of the Women's Headache Center near Boston, and a migraine sufferer herself, Dr. Bernstein has helped hundreds of her patients get better. Now, with The Migraine Brain, the most comprehensive, up-to-the-minute book on migraines ever written, you will be able to do the same—reduce the frequency and intensity of your migraines, learn how to prevent and curtail them and how to recover from them more quickly, and mitigate migraine's effects on every aspect of your life: in the workplace and at home and during sex and travel. Every migraine is different because everyone who gets a migraine has a distinctive “Migraine Brain” with its own sensitivities and triggers. That's why it's so important for you to develop a personalized wellness plan to radically reduce the number and severity of your migraines. Dr. Bernstein also explains why migraines happen, why they are so often misdiagnosed, and why so few people get the right treatment for them. She reveals the latest research that shows that Migraine Brains share a hypersensitivity to stimuli—the Migraine Brain can actually look different from others on a brain scan—and is more likely to experience a cascade of neurological reactions that give rise to the common clusters of migraine symptoms. This breakthrough medical knowledge makes treatment and recovery possible with new migraine-specific drugs as well as with complementary treatments such as yoga, biofeedback, and an exercise regimen. With the extraordinarily thorough recommendations of The Migraine Brain in your hands, you will be fully equipped with all the latest information you need to understand migraines and to help your family and co-workers understand that migraine isn't just a headache: it's a serious, yet treatable disease.

Author : Jeffrey L. Noebels,Massimo Avoli
Publisher : OUP USA
Page : 1258 pages
File Size : 47,6 Mb
Release : 2012-06-29
Category : Medical
ISBN : 9780199746545

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Jasper's Basic Mechanisms of the Epilepsies by Jeffrey L. Noebels,Massimo Avoli Pdf

Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

Author : Anne MacGregor,Alison Frith
Publisher : John Wiley & Sons
Page : 88 pages
File Size : 40,5 Mb
Release : 2013-05-20
Category : Medical
ISBN : 9781118682005

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ABC of Headache by Anne MacGregor,Alison Frith Pdf

In its different presentations, headache is one of the most commonsymptoms seen by family practitioners. The difficulty is indiagnosing the cause of the headache so that the appropriatetreatment is provided, or if referral to a specialist is therecommended course of action. The ABC of Headache helps with this dilemma and guidesthe healthcare professional to look for the possible causes ofpresenting symptoms. Based on real case histories, each chapterguides the reader from symptoms through to diagnosis andmanagement. This new ABC is a highly illustrated, informative, andpractical source of knowledge. With links to further informationand resources, it is a valuable text for healthcare professionalsat all levels of practice and training.

Author : Stephen D. Silberstein
Publisher : Routledge
Page : 298 pages
File Size : 47,6 Mb
Release : 2018-05-08
Category : Health & Fitness
ISBN : 9781351441315

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Headache in Clinical Practice by Stephen D. Silberstein Pdf

The authors of the first edition worked together again to revise data for the second edition of this popular volume. Based at three of the world's leading centers for the study and treatment of headache, these experts share their insights on every aspect of this common and irritating condition. In particular, the sections on migraine, cluster headache and vascular disease have been updated. Based on the classification system developed by the International Headache Society, Headache in Clinical Practice provides those interested in headache with an up-to-date compendium of current opinion, from epidemiology, pathophysiology and investigation, through options for intervention and management.

Author : Hubert Vaudry,Akira Arimura
Publisher : Springer Science & Business Media
Page : 406 pages
File Size : 51,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461502432

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Pituitary Adenylate Cyclase-Activating Polypeptide by Hubert Vaudry,Akira Arimura Pdf

Pituitary Adenylate Cyclase-Activating Polypeptide is the first volume to be written on the neuropeptide PACAP. It covers all domains of PACAP from molecular and cellular aspects to physiological activities and promises for new therapeutic strategies. Pituitary Adenylate Cyclase-Activating Polypeptide is the twentieth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.

Author : Frank Clifford Rose
Publisher : Demos Medical Publishing
Page : 296 pages
File Size : 51,8 Mb
Release : 1987
Category : Health & Fitness
ISBN : UOM:39015012582915

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Advances in Headache Research by Frank Clifford Rose Pdf

Author : Robert Vink,Mihai Nechifor
Publisher : University of Adelaide Press
Page : 354 pages
File Size : 49,6 Mb
Release : 2011
Category : Medical
ISBN : 9780987073051

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Magnesium in the Central Nervous System by Robert Vink,Mihai Nechifor Pdf

The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Author : Anonim
Publisher : Unknown
Page : 58 pages
File Size : 55,8 Mb
Release : 2001
Category : Chronically ill
ISBN : UOM:39015054148500

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Pain by Anonim Pdf

Author : Seymour Diamond
Publisher : Academic Press
Page : 334 pages
File Size : 46,7 Mb
Release : 2015-03-13
Category : Science
ISBN : 9780128011621

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Headache and Migraine Biology and Management by Seymour Diamond Pdf

There are two crucial issues in the treatment and management of headache patients: More than 50% of individuals experiencing headache have only been treated symptomatically, with no appropriate diagnosis established; and history and neurologic examination are essential to establishing a diagnosis, and thus selecting appropriate therapy. Headache and Migraine Biology and Management is a practical text that addresses these issues, featuring contributions from expert clinical authors. The book covers in detail topics including chronic and episodic migraine, post-traumatic headache, sinus headache, cluster headache, tension headache, and others. Chapters are also dedicated to treatment subjects, including psychiatric and psychological approaches, medication overuse, inpatient treatment, and pediatric issues. This book is an ideal resource for researchers and clinicians, uniting practical discussion of headache biology, current ideas on etiology, future research, and genetic significance and breakthroughs. This resource is useful to those who want to understand headache biology, treat and manage symptoms, and for those performing research in the headache field. A practical discussion of headache biology, current ideas on etiology, future research, and genetic significance and breakthroughs Features chapters from leading physicians and researchers in headache medicine Full-color text that includes both an overview of multiple disciplines and discusses the measures that can be used to treat headaches

Author : Jes Olesen
Publisher : Lippincott Williams & Wilkins
Page : 1212 pages
File Size : 41,6 Mb
Release : 2006
Category : Medical
ISBN : 9780781754002

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The Headaches by Jes Olesen Pdf

Established worldwide as the one definitive, encyclopedic reference on headache, The Headaches is now in its thoroughly revised, updated Third Edition. The foremost international authorities examine the mechanisms of over 100 types of headache and provide evidence-based treatment recommendations, including extensive tables of controlled clinical trials. This edition presents the revised International Headache Society classification of headaches and explains how to use this new classification for accurate diagnosis. Many headache entities are discussed for the first time, such as chronic migraines; primary headache attributed to sexual activity; primary stabbing, cough, exertional, and thunderclap headaches; hypnic headaches; and new daily persistent headaches. A new section focuses on childhood headaches. Chapters that focus on headaches in elderly patients and patients with psychiatric or medical diseases are also included.

Author : Messoud Ashina,Pierangelo Geppetti
Publisher : Springer
Page : 272 pages
File Size : 51,8 Mb
Release : 2015-04-14
Category : Medical
ISBN : 9783319156217

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Pathophysiology of Headaches by Messoud Ashina,Pierangelo Geppetti Pdf

This book provides a detailed overview of the current state of knowledge regarding the pathophysiology of both primary headaches – migraine, tension-type headache (TTH), and cluster headache – and the very important and frequent type of secondary headache, medication overuse headache (MOH). After an introductory chapter describing relevant neuroanatomy and vascular anatomy, the evidence gained from animal models regarding the pathophysiology of migraine and the other primary headaches is reviewed. Knowledge of the genetic component in the different types of headache is then examined with reference to recent evidence, for example regarding the implication of the trigeminovascular system and cortical spreading depression in migraine. Detailed information is provided on insights into primary headaches from imaging studies, including functional magnetic resonance imaging and positron emission tomography and on their neurophysiology and biochemistry. A further series of important chapters describe present knowledge of the pathophysiology of each specific type of headache and consider future directions. Written by acknowledged experts in their fields from Europe and the United States, clinicians and students will find Pathophysiology of Headaches to be an excellent source of up-to-date information on why patients experience headaches. In addition, it will be of value for pain researchers investigating the underlying mechanisms of headache.

Author : Katherine Foxhall
Publisher : Johns Hopkins University Press
Page : 293 pages
File Size : 43,7 Mb
Release : 2019-06-18
Category : Medical
ISBN : 9781421429489

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Migraine by Katherine Foxhall Pdf

Deeply researched and beautifully written, this fascinating and accessible study of one of our most common, disabling—and yet often dismissed—disorders will appeal to physicians, historians, scholars in medical humanities, and people living with migraine alike.