Neuroprotection In Autism Schizophrenia And Alzheimer S Disease

Author : Illana Gozes,Joseph Levine
Publisher : Academic Press
Page : 322 pages
File Size : 49,8 Mb
Release : 2019-10-16
Category : Medical
ISBN : 9780128140383

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Neuroprotection in Autism, Schizophrenia and Alzheimer's disease by Illana Gozes,Joseph Levine Pdf

Neuroprotection in Autism, Schizophrenia and Alzheimer's Disease provides an up-to-date overview on recent clinical studies and the similarities discovered in the most prevalent brain disorders. The book's content will help shed light on basic mechanisms and provide new avenues for early diagnosis toward disease prevention and disease modification. It is written for researchers, clinicians and medical physicians in neuroscience, neurology and psychiatry. Sections discuss the shared pathophysiological mechanisms that underlie autism, schizophrenia/mood disorders and Alzheimer’s disease, i.e. neurodevelopmental disorders, neuropsychiatric diseases and neurodegenerative disorders. Offers an up-to-date overview of basic and clinical studies concerning similarities in the most prevalent brain disorders Helps the reader become familiar with novel neuroprotective mechanisms and experimental treatment modalities in these difficult to treat disorders Written for researchers, clinicians and medical physicians in neuroscience, neurology and psychiatry

Author : Illana Gozes
Publisher : Academic Press
Page : 342 pages
File Size : 53,6 Mb
Release : 2016-12-30
Category : Medical
ISBN : 9780128037126

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Neuroprotection in Alzheimer's Disease by Illana Gozes Pdf

Neuroprotection in Alzheimer’s Disease offers a translational point-of-view from both basic and clinical standpoints, putting it on the cusp for further clinical development with its emphasis on nerve cell protection, including the accumulation of knowledge from failed clinical trials and new advances in disease management. This book brings together the latest findings, both basic, and clinical, under the same cover, making it easy for the reader to obtain a complete overview of the state-of-the-field and beyond. Alzheimer's disease is the most common form of dementia, accounting for 60 to 80 percent of dementia cases. It is a progressive brain disease that slowly destroys memory, thinking skills, and eventually, even the ability to carry out the simplest tasks. It is characterized by death of synapses coupled to death nerve cells and brain degeneration which is manifested by loss of cognitive abilities. Understanding neuroprotection in Alzheimer’s disease will pave the path to better disease management and novel therapeutics. Comprehensive reference detailing neuroprotection in Alzheimer’s Disease, with details on nerve cell protection and new advances in disease management Combines the knowledge and points-of-view of both medical doctors and basic scientists, putting the subject at the forefront for further clinical development Edited by one of the leading researchers in Alzheimer’s Disease

Author : Lidia V. Gabis,Josephine Barbaro,Raz Gross
Publisher : Frontiers Media SA
Page : 176 pages
File Size : 53,7 Mb
Release : 2022-02-15
Category : Medical
ISBN : 9782889716777

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Personalized Precision Medicine in Autism Spectrum Related Disorders by Lidia V. Gabis,Josephine Barbaro,Raz Gross Pdf

Author : Julien Santi-Rocca
Publisher : Springer Nature
Page : 400 pages
File Size : 54,6 Mb
Release : 2022-05-25
Category : Medical
ISBN : 9783030968816

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Periodontitis by Julien Santi-Rocca Pdf

Periodontitis is a disease that affects more than half the adult population in the world. Treatment is often based on ancient recommendations consisting in mechanically removing material from damaged zones. However, novel therapeutic management strategies exist, from prevention to efficient treatment, and regeneration. The need of integrative approaches to circumvent this worldwide pledge can be achieved through: A better understanding of this complex disease by promoting scientific research and a comprehensive multidisciplinary approach, including epidemiology, microbiology, immunology, physiology, therapeutics, psychology, etc. A better outreach by promoting vulgarization and recommendations for health professionals. A better information of the empowered patients, leading them to consider prevention and to take part in their therapeutic course. The book “Periodontitis: Advances in Experimental Research” includes a timely collection of chapters covering all the fields of research about periodontitis, consisting in concise reviews by the best specialists themselves and with clinical perspectives for periodontitis. Recent technological advances have allowed to explore shadowed areas of periodontology. The book “Periodontitis: Advances in Experimental Research” is a unique occasion to set a milestone for a more integrated field of periodontitis, with a broad scientific, medical, and public audience thanks to dedicated sections in each chapter: Abstract and main body (scientific audience and expert clinicians) Highlights (scientific audience and clinicians) Impact for Practice (clinicians and economical/political decision makers) Summary for Patients (patients and economical/political decision makers)

Author : Victor Corasolla Carregari
Publisher : Springer Nature
Page : 150 pages
File Size : 42,7 Mb
Release : 2022-08-27
Category : Science
ISBN : 9783031054600

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Understanding PTMs in Neurodegenerative Diseases by Victor Corasolla Carregari Pdf

This new volume, a part of the Proteomics, Metabolomics, Interactomics and Systems Biology series, will explain how proteomic studies of post-translational modifications (PTMs) can be applied to neurodegenerative diseases and relevant studies. The goal of the book is to increase awareness among researchers about how PTMs may be helpful in understanding mechanisms in various neurodegenerative diseases through proteomic studies. This book will serve as a tool for those who want to begin work in the proteomics field and explore how to implement PTMs studies into their work. Chapter authors will describe different PTMs enrichment methods developed by experts in the field so that researchers may learn to apply these methods and techniques to new studies. Divided into three sections, chapters will cover sample preparation, data quality, enrichment techniques, guidelines on how to analyze PTMs, and explain the role of PTMs and different brain diseases. Among those topics includes will be brain cancer, SLA disease, Parkinsons disease, muscular dystrophies, and schizophrenia. This volume will be useful for researchers and students studying brain and neurodegenerative diseases who are interested in delving into work with proteomic studies and PTMs.

Author : Donatella Degl’Innocenti,Marzia Vasarri
Publisher : MDPI
Page : 112 pages
File Size : 53,7 Mb
Release : 2021-05-18
Category : Medical
ISBN : 9783036507880

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Marine Anti-inflammatory Agents 2020 by Donatella Degl’Innocenti,Marzia Vasarri Pdf

This Special Issue covers original and innovative basic research regarding the anti-inflammatory potential of several classes of secondary metabolites (i.e., polyphenols, phytosterols, proteoglycans, and polysaccharides) in manifestations of acute and chronic inflammation in both in vitro and in vivo experimental models.

Author : Singh, Ajay,Yeh, Chia Jung,Blanchard, Sheresa,Anunciação, Luis
Publisher : IGI Global
Page : 590 pages
File Size : 40,5 Mb
Release : 2021-04-23
Category : Education
ISBN : 9781799876328

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Handbook of Research on Critical Issues in Special Education for School Rehabilitation Practices by Singh, Ajay,Yeh, Chia Jung,Blanchard, Sheresa,Anunciação, Luis Pdf

Rehabilitation professionals working with students with disabilities and the families of those students face unique challenges in providing inclusive services to special education student populations. There needs to be a focus on adaptive teaching methods that provide quality experience for students with varying disabilities to promote student success and inclusivity. Critical issues within these practices span autism, diverse students, gifted education, learning disabilities, behavioral and emotional disorders, and more. With having many different types of students with vastly different situations, it is important for rehabilitation professionals to understand the best practices and learning systems for special education students who have a wide range of needs and challenges. The Handbook of Research on Critical Issues in Special Education for School Rehabilitation Practices focuses on the issues and challenges rehabilitation professionals face in special education and how they can provide inclusive and effective services to diverse student populations. This book highlights topics such as culturally responsive teacher preparation, artificial intelligence in the classroom, universal design, inclusive development, and school rehabilitation and explores the effects these newfound practices in education have on various types of students with disabilities. This book is essential for special education teachers, administrators, counselors, practitioners, researchers, academicians, and students interested in the new methods, theories, and solutions for the best practices in inclusive and effective special education.

Author : Akhlaq A. Farooqui
Publisher : Academic Press
Page : 404 pages
File Size : 54,5 Mb
Release : 2020-09-07
Category : Medical
ISBN : 9780128217016

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Molecular Aspects of Neurodegeneration, Neuroprotection, and Regeneration in Neurological Disorders by Akhlaq A. Farooqui Pdf

Molecular Aspects of Neurodegeneration, Neuroprotection, and Regeneration in Neurological Disorders presents readers with comprehensive and cutting-edge information on the neurochemical mechanisms of various types of neurological disorders. The book covers information on signal transduction processes associated with neurochemistry of neurological disorders, including neurodegenerative, neurotraumatic, and neuropsychiatric disorders. The book also discusses risk factors, symptoms, pathogenesis, biomarkers, and the potential treatments of neurological disorders. The comprehensive information in this monograph may not only help in early detection of various neurological disorders, but will also promote the discovery of new drugs. Provides a comprehensive overview of the molecular aspects of neurodegeneration, neuroprotection, and neuro-regeneration, along with therapeutic strategies for various types of neurological disorders Provides cutting-edge research information on the signal transduction processes associated with the neurochemistry of neurological disorders Discusses risk factors, symptoms, pathogenesis, biomarkers, and the potential for treatments of neurological disorders

Author : C. Laura Sayas,Monica Mendes Sousa,Jesus Avila
Publisher : Frontiers Media SA
Page : 185 pages
File Size : 52,6 Mb
Release : 2020-03-25
Category : Electronic
ISBN : 9782889635528

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Shaping the Brain by Neuronal Cytoskeleton: from Development to Disease and Regeneration by C. Laura Sayas,Monica Mendes Sousa,Jesus Avila Pdf

Author : Surya Pratap Singh,Hagera Dilnashin,,Hareram Birla,Chetan Keswani
Publisher : Bentham Science Publishers
Page : 417 pages
File Size : 44,7 Mb
Release : 2022-12-07
Category : Medical
ISBN : 9789815050875

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Indopathy for Neuroprotection: Recent Advances by Surya Pratap Singh,Hagera Dilnashin,,Hareram Birla,Chetan Keswani Pdf

Degenerative nerve diseases are age-related, progressive and cause irreversible neurological loss that may lead too death. Chronic diseases like amylotrophic lateral sclerosis, Huntington’s disease, Alzheimer’s disease, and Parkinson’s disease are associated with insoluble protein depositions and pose serious health challenges that may intensify in the coming decades. Current therapies only help to alleviate some of the physical or mental symptoms associated with neurodegenerative diseases, although there is currently no remedy for slow disease progression. In recent years, attempts have been made to discover a mechanism for neurodegenerative diseases and prospective treatment that may help mitigate aging effects and prevent these diseases. Natural products have been a constant source of new approaches for the treatment of neurodegenerative diseases, in particular plant alkaloids and polyphenolic compounds. Indopathy for Neuroprotection: Recent Advances highlights herbal treatments that are preferred over conventional treatments in some regions. Book chapters focus on the effects of various medicinal plants that have shown promise in reversing pathological symptoms of neurodegenerative disease and highlight the neuroprotective role of medicinal herbal phytochemicals and their mechanism of action. The book serves as a reference for pharmacology and herbal medicine scholars as well as healthcare workers interested in information about alternative and complementary therapies for neurological disorders.

Author : Joaquim Ros
Publisher : John Wiley & Sons
Page : 416 pages
File Size : 47,8 Mb
Release : 2017-06-26
Category : Science
ISBN : 9781119074915

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Protein Carbonylation by Joaquim Ros Pdf

Protein carbonylation has attracted the interest of a great number of laboratories since the pioneering studies at the Earl Stadtman’s lab at NIH started in early 1980s. Since then, detecting protein carbonyls in oxidative stress situations became a highly efficient tool to uncover biomarkers of oxidative damage in normal and altered cell physiology. In this book, research groups from several areas of interest have contributed to update the knowledge regarding detection, analyses and identification of carbonylated proteins and the sites where these modifications occur. The scientific community will benefit from these reviews since they deal with specific, detailed technical approaches to study formation and detection of protein carbonyls. Moreover, the biological impact of such modifications in metabolic, physiologic and structural functions and, how these alterations can help understanding the downstream effects on cell function are discussed. Oxidative stress occurs in all living organisms and affects proteins and other macromolecules: Protein carbonylation is a measure of oxidative stress in biological systems Mass spectrometry, fluorescent labelling, antibody based detection, biotinylated protein selection and other methods for detecting protein carbonyls and modification sites in proteins are described Aging, neurodegenerative diseases, obstructive pulmonary diseases, malaria, cigarette smoke, adipose tissue and its relationship with protein carbonylation Direct oxidation, glycoxidation and modifications by lipid peroxidation products as protein carbonylation pathways Emerging methods for characterizing carbonylated protein networks and affected metabolic pathways

Author : Marcos Roberto de Oliveira
Publisher : Elsevier
Page : 2202 pages
File Size : 42,9 Mb
Release : 2023-11-24
Category : Science
ISBN : 9780443237645

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Natural Molecules in Neuroprotection and Neurotoxicity by Marcos Roberto de Oliveira Pdf

Natural Molecules in Neuroprotection and Neurotoxicity brings together research in the area of natural compounds and their dual effects of neuroprotection and neurotoxicity when interacting with brain cells. This book is organized into four sections that address molecular mechanism underlying neuroprotection and neurotoxicity, neuroprotection mediated by natural molecules, neurotoxicity induced by natural compounds and nanotechnology-related strategies utilized in neuroprotection. Written by well-known researchers all over the world, chapters provide an in-depth analysis of numerous molecules, such as algae, plant and fungus-derived molecules, and comprehensively discuss their mechanisms of action and possible clinical applications. This book provides an essential reference for researchers and clinical scientists interested in the effects of natural compounds on the human health and disease. Covers both neuroprotective and neurotoxic outcomes resulted from the exposure of brain cells to natural molecules Analyzes numerous natural compounds, including animal, vegetal, fungal, bacterial, and marine-derived molecules Discusses the effects of the metabolism of microbiota on the biotransformation of natural molecules and the consequences of these processes on brain cells Contains a section focused on the nanotechnology-related strategies utilized to enhance the bioavailability of natural molecules to brain cells

Author : Lucia Ciranna,David Vaudry,Dora Reglodi,Billy K. C. Chow
Publisher : Frontiers Media SA
Page : 104 pages
File Size : 45,9 Mb
Release : 2021-11-01
Category : Science
ISBN : 9782889715640

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Novel Therapeutic Potential for Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP), Vasoactive Intestinal Peptide (VIP) and related peptides in cognition deficits by Lucia Ciranna,David Vaudry,Dora Reglodi,Billy K. C. Chow Pdf

Author : Salam Salloum-Asfar,Javier Corral,Jesualdo Tomás Fernández-Breis,Nasser H. Zawia
Publisher : Frontiers Media SA
Page : 255 pages
File Size : 45,8 Mb
Release : 2023-07-24
Category : Science
ISBN : 9782832529942

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Molecular advances and applications of machine learning in understanding autism and comorbid psychiatric disorders by Salam Salloum-Asfar,Javier Corral,Jesualdo Tomás Fernández-Breis,Nasser H. Zawia Pdf

Author : Yoichi Robertus Fujii
Publisher : Springer Nature
Page : 240 pages
File Size : 51,7 Mb
Release : 2023-09-14
Category : Medical
ISBN : 9789819931651

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The MicroRNA 2000 Transformer by Yoichi Robertus Fujii Pdf

The second edition includes new findings that were only a theory in the first edition, clarifying what is beginning to be proven true. All chapters have been updated, and new data on the analysis of major depressive disorder from exosome microRNA (miRNA) in plasma, traumatic brain injury, and Alzheimer's disease, brain glioma from cerebrospinal fluid miRNA, liver cancer, induced pluripotent stem (iPS) cell tumorigenesis, and other topics have been added. As predicted in the first edition, diseases can be predicted using the miRNA memory package (MMP) and miRNA entangling target sorting (METS), which could clarify the etiology of human diseases. Because researchers are investigating the relationship between circulating miRNAs and human diseases to develop new medicines, miRNA deep sequencing and detection methods will be high-speed and clever. The microRNA 2000 Transformer - Quantum Computing and Artificial Intelligence for Health is aimed at intermediate and advanced scientists, clinicians, students, and science enthusiasts. The Author hopes to lay the groundwork for future human health innovation.