New Directions In Understanding Dementia And Alzheimer S Disease

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New Directions in Understanding Dementia and Alzheimer’s Disease

Author : Taher Zandi,Richard J. Ham
Publisher : Springer Science & Business Media
Page : 165 pages
File Size : 46,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461306658

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New Directions in Understanding Dementia and Alzheimer’s Disease by Taher Zandi,Richard J. Ham Pdf

The management of Alzheimer's Disease and the related dementias is one of the major challenges to health care professionals and American society-at-large for the coming decade and the coming millennium. The rapid growth of the over-eighty-five population, the group which, as recent studies have confirmed and as many of us clinicians have long suspected, has an even higher prevalence than previously quoted of dementing disorders, is the major cause of this. We are thus challenged by, as Bernard Issacs used to call it, "the survival of the unfittest," as well as the oPtimistic approach of "bringing life to years," as John F. Kennedy said. The fact is that we, as a society, tend to confuse "treatment" and "cure" (and "prevention"). As the proceedings of the conference which this book represents emphasize, there is considerable work going on about the potential prevention of, or at least the reduction of, symptomatology in these illnesses by interventions genetically, chemIcally, and so forth. However, the more we find out, the more complicated it becomes, and the more heterogeneous Alzheimer's and the related disorders appear to be, not only in their manifestations (as clinicians have long recognized) but also in the individual initiating and underlying processes. For these reasons, absolute preventive techniques or the likelihood of an intervention which will reverse the process in a high proportion of patients, do not appear to be just around the corner.

Understanding Alzheimer's Disease

Author : Alzheimer's Disease and Related Disorders Association (Chicago, Ill.)
Publisher : Scribner Book Company
Page : 406 pages
File Size : 47,9 Mb
Release : 1988
Category : Family & Relationships
ISBN : 0684184753

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Understanding Alzheimer's Disease by Alzheimer's Disease and Related Disorders Association (Chicago, Ill.) Pdf

This comprehensive guide includes a checklist of early warning signs, the latest data pertaining to diagnosis, treatment, possible causes, and promising research, and information on the legal rights of patients and their families.

American Dementia

Author : Daniel R. George,Peter J. Whitehouse
Publisher : JHU Press
Page : 425 pages
File Size : 55,8 Mb
Release : 2021-09-14
Category : Health & Fitness
ISBN : 9781421440477

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American Dementia by Daniel R. George,Peter J. Whitehouse Pdf

"The authors argue for a strong connection between public health and social policies that have boosted access to education; quality health care; cleaner air, soil, and water; and a reduction in Alzheimer's disease and dementia. They question the assumption of many that developing a pharmaceutical cure is the best hope for addressing Alzheimer's"--

Understanding Alzheimer's Disease

Author : Neal R. Cutler
Publisher : Univ. Press of Mississippi
Page : 168 pages
File Size : 40,8 Mb
Release : 2010-02-11
Category : Health & Fitness
ISBN : 9781604737004

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Understanding Alzheimer's Disease by Neal R. Cutler Pdf

Alzheimer's disease has received growing attention in recent years because the affected population is growing quickly as life spans in America creep ever upward. As they near retirement, many Americans start to fear that any minor memory lapse-misplacing the keys or forgetting a name-might spell Alzheimer's. In reality such incidents are a normal part of the aging process. In Alzheimer's disease, such incidents progress to a point at which they interfere with normal daily activities on a regular basis, and memory loss becomes progressively more disabling. This book is written for anyone interested in learning more about Alzheimer's disease-people who have it, their families and caregivers, professionals who serve such people, teachers, and anyone with a general interest in the disease. An important feature of this book is clear explanation of the basic biology of the disease. Here is information about who gets the disease, how it is diagnosed, and what happens to people who have it. A large section is devoted to the subject of caring for affected individuals, including legal and financial planning advice and pointers for finding outside support services. Existing treatments are discussed along with suggestions for handling many symptoms without drugs. Understanding Alzheimer's Disease describes the most current knowledge of how and why it arises and gives information about the many avenues being explored in search of a cure. With its chapters on causes and on the search for treatments, this guide will be of interest to a wider section of the population than other books on the disease.

Dementia

Author : Susan Hunter
Publisher : Jessica Kingsley Publishers
Page : 228 pages
File Size : 40,9 Mb
Release : 1997-01-01
Category : Medical
ISBN : 1853023124

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Dementia by Susan Hunter Pdf

As a focus for academic and professional study, dementia has moved rapidly from the margin to the mainstream during the last decade. Understanding of this distressing condition, its aetiology and recognition, has become much more widespread and sophisticated. Building on such clinical knowledge, this book challenges the reader - to think ethically and in a person-centred way about the implications of dementia at a personal, planning and service provision level - to consider consumer perspectives, not only those of carers but also the much neglected views of individuals with dementia - to explore less well documented areas such as dementia and Down's Syndrome, depression and early onset dementia. In conclusion, the book illuminates selected topical developments in service provision such as community care, advocacy and aspects of the built and social care environment.

2015: Which new directions for Alzheimer's disease?

Author : Ludovic Martin
Publisher : Frontiers Media SA
Page : 125 pages
File Size : 40,6 Mb
Release : 2015-06-03
Category : Alzheimer's disease
ISBN : 9782889195350

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2015: Which new directions for Alzheimer's disease? by Ludovic Martin Pdf

According to the World Health Organization, more than 40 million people in the world are affected with dementia. To date, 60-70% of the cases of dementia are attributed to the Alzheimer's disease (AD). This neurodegenerative disorder gradually takes place over a period of at least 20 years before the onset of symptoms, which are impaired memory, apathy and depression. The characteristics of AD consist in neurofibrillary tangles (intraneuronal aggregates of hyperphosphorylated tau proteins) and senile plaques (dense extraneuronal deposits composed of amyloid ß (Aß)). The other features linked to these two core pathological hallmarks of AD are inflammation, oxidative stress, progressive synaptic and neuronal loss. In past years, some of the emerging therapeutic strategies against AD were employed to deal with the pathological hallmarks of the disease. Science teams all over the world try to restore the tau phosphorylation equilibrium. Their purpose is to interfere with the aggregation of tau and decrease its amount of proteins per se as well. Furthermore, they are trying either to stimulate the elimination processes of the aggregated tau proteins or to stop the formation of Aß peptides. This could be reached by the stimulation of the classic techniques of protein degradation such as the autophagic pathway, or by the targeted immunotherapy. In this Research Topic, we wish to summarize and review the etiology of AD and the related therapeutic opportunities for the next decades. To fully understand the precise mechanisms underlying AD, research findings, reviews, new insights and new approaches include AD and related tauopathies, tau phosphorylation balance, pharmacological compounds against AD, neuroprotection strategies and new therapeutic ways but also risk factors for AD and AD genetic information are included in this issue.

New Directions in Aging Research

Author : Ruby R. Brougham
Publisher : Nova Science Publishers
Page : 226 pages
File Size : 52,9 Mb
Release : 2009
Category : Aging
ISBN : CHI:092452659

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New Directions in Aging Research by Ruby R. Brougham Pdf

One of the greatest challenges of the 21st century is global ageing. A primary objective of this book is to review research that is at the forefront in providing information regarding the decline, maintenance, and improvements in health and cognition that are associated with age. Another objective is to provide information regarding pioneering methods to ameliorate age-related declines. It brings together scholars with a wide variety of expertise who present innovative ideas about lifestyle and brain health, quality of life issues, memory interventions, methodology for pain assessment, health communication, decision-making, future time perspective, and retirement goals. The reader will finish this book with a greater understanding of the problems and potential solutions for addressing the important problems of an ageing population. This timely book will make an important contribution to the current aging literature by offering new ideas to stimulate further research and application in understanding health, cognition, and ageing. This book is appropriate for advanced undergraduate students, graduate students, and professionals who study or work in the fields of psychology, gerontology, social work, human development and health fields such as nursing, physical therapy, and occupational therapy.

National Library of Medicine Current Catalog

Author : National Library of Medicine (U.S.)
Publisher : Unknown
Page : 968 pages
File Size : 44,9 Mb
Release : 1991
Category : Medicine
ISBN : MINN:31951D00419044S

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National Library of Medicine Current Catalog by National Library of Medicine (U.S.) Pdf

New Directions in Geriatric Medicine

Author : Lee Ann Lindquist
Publisher : Springer
Page : 159 pages
File Size : 46,6 Mb
Release : 2016-04-09
Category : Medical
ISBN : 9783319281377

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New Directions in Geriatric Medicine by Lee Ann Lindquist Pdf

This book is designed to present the clinical geriatric trends within general internal medicine and family practice, which practitioners often encounter in caring for their older adult patients. Chapters focus on increasingly difficult clinical decisions that practitioners have to make in caring for older adults, who often experience medical complications due to memory loss, physical disability, and multiple chronic conditions. Written by experts in geriatric medicine, each of these chapters start with the most up-to-date clinical geriatric research and provide specific examples or case studies on how to use this information to address the clinical needs of older adult patients. In addition, there is a set of concise “take-home points” for each chapter that are easy to commit to memory and implement in clinical care of aging patients. As the only book to focus on current trends in geriatric research and evidence-based eldercare practice, Clinical Trends in Geriatric Medicine is of great value to internists, family practitioners, geriatricians, nurses, and physician assistants who care for older adults.

Understanding Alzheimer's Disease

Author : Miriam K. Aronson
Publisher : Diane Books Publishing Company
Page : 380 pages
File Size : 44,8 Mb
Release : 1998-09-01
Category : Health & Fitness
ISBN : 0788155822

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Understanding Alzheimer's Disease by Miriam K. Aronson Pdf

An in-depth, comprehensive guide to a devastating disease that affects over 3 mill. Amer. Pt. I covers diagnosis, possible causes, and treatment strategies. Pt. II focuses on coping with Alzheimer1s disease (AD), with attention to the needs of the family and friends of Alzheimer patients. Discusses: dealing with the emotional turmoil of the disease; helping younger family members cope with the illness of a loved one; joining a support group; services for patients and families; and how and when to place a loved one in a nursing home. Pt. III discusses the legal and financial aspects of AD, including how to do legal planning, and the rights of and duties to the terminally ill.

Communication and Swallowing Changes in Healthy Aging Adults

Author : Angela Burda
Publisher : Jones & Bartlett Learning
Page : 210 pages
File Size : 55,7 Mb
Release : 2010-10-22
Category : Language Arts & Disciplines
ISBN : 9780763776565

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Communication and Swallowing Changes in Healthy Aging Adults by Angela Burda Pdf

Communication and Swallow Changes in Healthy Aging Adults compiles and presents the available research on healthy aging adults’ performance and abilities in the following areas: auditory comprehension, reading comprehension, speaking, writing, voice and motor speech abilities, cognition, and swallowing. This text also presents principles from the World Health Organization’s International Classification of Functioning, Disability and Health and its applications to aging adults. One of the first texts to cover these principles, this book will address the need for a comprehensive view of communication and swallow issues in aging for students of speech-language pathology. Speech-language pathologist students will learn how to fully compare what would be considered normal for their elderly patients rather than overestimating or underestimating what aging adults are capable of doing. Knowing what would be considered within the spectrum of normal, will help speech-language pathologists to address therapy as effectively as possible. Having this information at hand is particularly important as the nation’s population is aging at a rapid rate and there is a need for evidence-based practice in speech-language pathology. Written in an easy to follow format, Communication and Swallow Changes in Healthy Aging Adults includes original research data, discussion questions and a list of Quick Facts at the end of each chapter to summarize key points. This text will serve as a useful resource as students see elderly clients in on-campus speech and hearing clinics and when they intern at hospitals and long-term care facilities. Instructor Resources: PowerPoint Slides and an Image Bank Testimonial: “Communication and Swallowing Changes in Healthy Aging Adults is a handy text, portable, and logically organized. The information is easy to follow complimented by information presented in tables/charts. This text would be helpful to a practicing therapist when making a differential diagnosis between a normal vs. atypical aging process. Communication and Swallowing Changes in Healthy Aging Adults would be an appropriate text for courses in Communications Disorders Departments for graduate students in a neuro course or a neurogenic communication disorders course, and in lifespan development courses as in the field of Psychology and Gerontology.” ~ Susan Durnford, M.S.,CCC-SLP, Clinical Assistant Professor, Department of Speech-Language Pathology & Audiology, Ithaca College

Preventing Cognitive Decline and Dementia

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Preventing Dementia and Cognitive Impairment
Publisher : National Academies Press
Page : 181 pages
File Size : 41,7 Mb
Release : 2017-10-05
Category : Medical
ISBN : 9780309459594

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Preventing Cognitive Decline and Dementia by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Preventing Dementia and Cognitive Impairment Pdf

Societies around the world are concerned about dementia and the other forms of cognitive impairment that affect many older adults. We now know that brain changes typically begin years before people show symptoms, which suggests a window of opportunity to prevent or delay the onset of these conditions. Emerging evidence that the prevalence of dementia is declining in high-income countries offers hope that public health interventions will be effective in preventing or delaying cognitive impairments. Until recently, the research and clinical communities have focused primarily on understanding and treating these conditions after they have developed. Thus, the evidence base on how to prevent or delay these conditions has been limited at best, despite the many claims of success made in popular media and advertising. Today, however, a growing body of prevention research is emerging. Preventing Cognitive Decline and Dementia: A Way Forward assesses the current state of knowledge on interventions to prevent cognitive decline and dementia, and informs future research in this area. This report provides recommendations of appropriate content for inclusion in public health messages from the National Institute on Aging.

Future Directions for the Demography of Aging

Author : National Academies of Sciences, Engineering, and Medicine,Division of Behavioral and Social Sciences and Education,Committee on Population
Publisher : National Academies Press
Page : 409 pages
File Size : 45,7 Mb
Release : 2018-07-21
Category : Social Science
ISBN : 9780309474108

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Future Directions for the Demography of Aging by National Academies of Sciences, Engineering, and Medicine,Division of Behavioral and Social Sciences and Education,Committee on Population Pdf

Almost 25 years have passed since the Demography of Aging (1994) was published by the National Research Council. Future Directions for the Demography of Aging is, in many ways, the successor to that original volume. The Division of Behavioral and Social Research at the National Institute on Aging (NIA) asked the National Academies of Sciences, Engineering, and Medicine to produce an authoritative guide to new directions in demography of aging. The papers published in this report were originally presented and discussed at a public workshop held in Washington, D.C., August 17-18, 2017. The workshop discussion made evident that major new advances had been made in the last two decades, but also that new trends and research directions have emerged that call for innovative conceptual, design, and measurement approaches. The report reviews these recent trends and also discusses future directions for research on a range of topics that are central to current research in the demography of aging. Looking back over the past two decades of demography of aging research shows remarkable advances in our understanding of the health and well-being of the older population. Equally exciting is that this report sets the stage for the next two decades of innovative researchâ€"a period of rapid growth in the older American population.

Biological Reactive Intermediates IV

Author : Charlotte M. Witmer,Robert R. Snyder,David J. Jollow,George F. Kalf,James J. Kocsis
Publisher : Springer Science & Business Media
Page : 848 pages
File Size : 43,5 Mb
Release : 2013-03-09
Category : Medical
ISBN : 9781468458770

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Biological Reactive Intermediates IV by Charlotte M. Witmer,Robert R. Snyder,David J. Jollow,George F. Kalf,James J. Kocsis Pdf

The finding that chemicals can be metabolically activated to yield reactive chemical species capable of covalently binding to cellular macromolecules and the concept that these reactions could initiate toxicological and carcinogenic events stimulated a meeting by a small group of toxicologists at the University of Turku, in Finland, in 1975 (Jollow et al. , 1977). The growing interest in this field of research led to subsequent symposia at the University of Surrey, in England in 1980 (Snyder et al. , 1982), and the University of Maryland in the U. S. A. in 1985 (Kocsis et al. , 1986). The Fourth International Symposium on Biological Reactive Intermediates was hosted by the Center for Toxicology at the University of Arizona and convened in Tucson, Arizona, January 14-17, 1990. Over 300 people attended. There were 60 platform presentations by invited speakers, and 96 volunteer communications in the form of posters were offered. These meetings have grown from a small group of scientists working in closely related areas to a major international series of symposia which convene every five years to review, and place in context, the latest advances in our understanding of the formation, fate and consequences of biological reactive intermediates. The Organizing Committee: Allan H. Conney, Robert Snyder (Co-chairman), and Charlotte M. Witmer (Rutgers University, Piscataway, NJ), David J. Jollow Co chairman) (Medical University, South Carolina, Charleston, SC), 1. Glenn Sipes (Co chairman) (University of Arizona, Tucson, AZ), James J. Kocsis and George F.