Nmr Of Biomolecules

Author : Andrew J. Dingley,A. J. Dingley,Steven M. Pascal
Publisher : IOS Press
Page : 488 pages
File Size : 43,8 Mb
Release : 2011
Category : Medical
ISBN : 9781607506942

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Biomolecular NMR Spectroscopy by Andrew J. Dingley,A. J. Dingley,Steven M. Pascal Pdf

Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful technique for characterization of biomolecular structures at atomic resolution in the solution state. This timely book, entitled "Biomolecular NMR Spectroscopy," focuses on the latest state-of-the-art NMR techniques for characterization of biological macromolecules in the solid and solution state. The editors, Dr. Andrew Dingley (University of Auckland, New Zealand) and Dr. Steven Pascal (Massey University, New Zealand) have organized the book into four sections, covering the following topics: sample preparation, structure and dynamics of proteins, structure and dynamics of nucleic acids and protein-nucleic acid complexes, and rapid and hybrid techniques--

Author : K.V.R. Chary,Girjesh Govil
Publisher : Springer Science & Business Media
Page : 552 pages
File Size : 47,8 Mb
Release : 2008-04-01
Category : Science
ISBN : 9781402066801

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NMR in Biological Systems by K.V.R. Chary,Girjesh Govil Pdf

During teaching NMR to students and researchers, we felt the need for a text-book which can cover modern trends in the application of NMR to biological systems. This book covers the entire area of NMR in Biological Sciences (Biomolecules, cells and tissues, animals, plants and drug design). As well as being useful to researchers, this is an excellent book for teaching a course on NMR in Biological Systems.

Author : Ivano Bertini,Kathleen S. McGreevy,Giacomo Parigi
Publisher : John Wiley & Sons
Page : 15 pages
File Size : 50,9 Mb
Release : 2012-04-16
Category : Science
ISBN : 9783527328505

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NMR of Biomolecules by Ivano Bertini,Kathleen S. McGreevy,Giacomo Parigi Pdf

NMR is one of the most powerful methods for imaging of biomolecules. This book is the ultimate NMR guide for researchers in the biomedical community and gives not only background and practical tips but also a forward looking view on the future of NMR in systems biology.

Author : Ivano Bertini,Kathleen S. McGreevy,Giacomo Parigi
Publisher : John Wiley & Sons
Page : 15 pages
File Size : 45,7 Mb
Release : 2012-02-23
Category : Science
ISBN : 9783527644513

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NMR of Biomolecules by Ivano Bertini,Kathleen S. McGreevy,Giacomo Parigi Pdf

NMR is one of the most powerful methods for imaging of biomolecules. This book is the ultimate NMR guide for researchers in the biomedical community and gives not only background and practical tips but also a forward looking view on the future of NMR in systems biology.

Author : Enrico Ravera,Giacomo Parigi,Claudio Luchinat
Publisher : Royal Society of Chemistry
Page : 340 pages
File Size : 55,7 Mb
Release : 2018-08-06
Category : Science
ISBN : 9781788010863

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Paramagnetism in Experimental Biomolecular NMR by Enrico Ravera,Giacomo Parigi,Claudio Luchinat Pdf

Paramagnetic NMR is a growing technique that represents an increasingly important tool for the investigation of biomolecules. This book presents an update and overview of the paramagnetic NMR phenomena and effects as well as guidelines for practical implementation of state-of-the-art experiments. All experiments are supported by a solid theoretical foundation. Areas mentioned are the development of solid state NMR, the use of paramagnetic tags providing information on the structure and mobility of the investigated systems, and dynamic nuclear polarization to increase sensitivity. Compiled by experts in the field, this book has international appeal for researchers as well as students interested in magnetic resonance and structural biology who require experimental support and accessible information.

Author : John L. Markley,Stanley J. Opella
Publisher : Oxford University Press
Page : 375 pages
File Size : 43,7 Mb
Release : 1997-01-30
Category : Medical
ISBN : 9780195094688

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Biological NMR Spectroscopy by John L. Markley,Stanley J. Opella Pdf

This book presents a critical assessment of progress on the use of nuclear magnetic resonance spectroscopy to determine the structure of proteins, including brief reviews of the history of the field along with coverage of current clinical and in vivo applications. The book, in honor of Oleg Jardetsky, one of the pioneers of the field, is edited by two of the most highly respected investigators using NMR, and features contributions by most of the leading workers in the field. It will be valued as a landmark publication that presents the state-of-the-art perspectives regarding one of today's most important technologies.

Author : Lawrence Berliner
Publisher : Springer
Page : 185 pages
File Size : 40,6 Mb
Release : 2015-08-24
Category : Science
ISBN : 9781489976215

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Protein NMR by Lawrence Berliner Pdf

This book covers new techniques in protein NMR, from basic principles to state-of-the-art research. It covers a spectrum of topics ranging from a “toolbox” for how sequence-specific resonance assignments can be obtained using a suite of 2D and 3D NMR experiments and tips on how overlap problems can be overcome. Further topics include the novel applications of Overhauser dynamic nuclear polarization methods (DNP), assessing protein structure, and aspects of solid-state NMR of macroscopically aligned membrane proteins. This book is an ideal resource for students and researchers in the fields of biochemistry, chemistry, and pharmacology and NMR physics. Comprehensive and intuitively structured, this book examines protein NMR and new novel applications that include the latest technological advances. This book also has the features of: • A selection of various applications and cutting-edge advances, such as novel applications of Overhauser dynamic nuclear polarization methods (DNP) and a suite of 2D and 3D NMR experiments and tips on how overlap problems can be overcome • A pedagogical approach to the methodology • Engaging the reader and student with a clear, yet critical presentation of the applications

Author : Marius Clore,Jennifer Potts
Publisher : Royal Society of Chemistry
Page : 250 pages
File Size : 46,7 Mb
Release : 2012-08-21
Category : Science
ISBN : 9781849735391

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Recent Developments in Biomolecular NMR by Marius Clore,Jennifer Potts Pdf

NMR spectroscopy is widely used in biomolecular science particularly for structure determination of proteins, nucleic acids and carbohydrates. Much of the innovation within NMR spectroscopy has been within the field of protein NMR spectroscopy, an important technique in structural biology. Filling a gap in the literature, this book draws together experts in the field to discuss the real advances in NMR methods that have occurred or have an impact on the biomolecular field in the last few years. The coverage includes recent developments in using NMR for determination of protein structures, membrane proteins, the dynamics of RNA and advances in NMR in drug discovery. Edited by leading biological NMR spectroscopists, the book is essential reference for researchers in industry and academia interested in or joining this bioanalytical field.

Author : N. Rama Krishna,Lawrence Berliner
Publisher : Springer Science & Business Media
Page : 565 pages
File Size : 45,6 Mb
Release : 1999-06-30
Category : Medical
ISBN : 9780306459535

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Structure Computation and Dynamics in Protein NMR by N. Rama Krishna,Lawrence Berliner Pdf

Volume 17 is the second in a special topic series devoted to modern techniques in protein NMR, under the Biological Magnetic Resonance series. Volume 16, with the subtitle Modern Techniques in Protein NMR , is the first in this series. These two volumes present some of the recent, significant advances in the biomolecular NMR field with emphasis on developments during the last five years. We are honored to have brought together in these volume some of the world s foremost experts who have provided broad leadership in advancing this field. Volume 16 contains - vances in two broad categories: I. Large Proteins, Complexes, and Membrane Proteins and II. Pulse Methods. Volume 17 contains major advances in: I. Com- tational Methods and II. Structure and Dynamics. The opening chapter of volume 17 starts with a consideration of some important aspects of modeling from spectroscopic and diffraction data by Wilfred van Gunsteren and his colleagues. The next two chapters deal with combined automated assignments and protein structure determination, an area of intense research in many laboratories since the traditional manual methods are often inadequate or laborious in handling large volumes of NMR data on large proteins. First, Werner Braun and his associates describe their experience with the NOAH/DIAMOD protocol developed in their laboratory.

Author : Guang Zhu
Publisher : Springer Science & Business Media
Page : 255 pages
File Size : 47,6 Mb
Release : 2012-03-28
Category : Science
ISBN : 9783642289163

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NMR of Proteins and Small Biomolecules by Guang Zhu Pdf

Application of NMR and Molecular Docking in Structure-Based Drug Discovery, by Jaime L. Stark and Robert Powers NMR as a Unique Tool in Assessment and Complex Determination of Weak Protein-Protein Interactions, by Olga Vinogradova and Jun Qin The Use of Residual Dipolar Coupling in Studying Proteins by NMR, by Kang Chen und Nico Tjandra NMR Studies of Metalloproteins, by Hongyan Li and Hongzhe Sun Recent Developments in 15N NMR Relaxation Studies that Probe Protein Backbone Dynamics, by Rieko Ishima Contemporary Methods in Structure Determination of Membrane Proteins by Solution NMR, by Tabussom Qureshi and Natalie K. Goto Protein Structure Determination by Solid-State NMR, by Xin Zhao Dynamic Nuclear Polarization: New Methodology and Applications, by Kong Hung Sze, Qinglin Wu, Ho Sum Tse and Guang Zhu

Author : Hanudatta S. Atreya
Publisher : Springer Science & Business Media
Page : 219 pages
File Size : 44,5 Mb
Release : 2012-10-18
Category : Medical
ISBN : 9789400749542

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Isotope labeling in Biomolecular NMR by Hanudatta S. Atreya Pdf

NMR spectroscopy has undergone a revolution in recent years with the advent of several new methods overcoming the problems of sensitivity and resolution. Recent developments in biotechnology have made it easier and economical to introduce 13C, 15N and 2H into proteins and nucleic acids. At the same time, there has been an explosion in the number of NMR experiments that utilize such isotope labeled samples. Thus, a combination of isotopic labeling and multidimensional, multinuclear NMR has opened up new avenues for structural studies of proteins, nucleic acids and their complexes. This book will focus on recent developments in isotope labeling methods for structural studies of small molecules, peptides, proteins and nucleic acids. The aim of the book is to serve as a compendium of isotope labeling for the biomolecular NMR community providing comprehensive coverage of the existing methods and latest developments along with protocols and practical hints on the various experimental aspects. The book will cover a wide range of topics in isotope labeling under one title including emerging areas of metabolonomics and solid state NMR.

Author : Anonim
Publisher : Academic Press
Page : 670 pages
File Size : 55,8 Mb
Release : 2005-05-04
Category : Science
ISBN : 9780080549477

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Nuclear Magnetic Resonance of Biological Macromolecules, Part C by Anonim Pdf

The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences. Nuclear Magnetic Resonance of Biological Macromolecules, Part C is written with a "hands-on" perspective. That is, practical applications with critical evaluations of methodologies and experimental considerations needed to design, execute, and interpret NMR experiments pertinent to biological molecules. * One of the most highly respected publications in the field of biochemistry since 1955 * Frequently consulted, and praised by researchers and reviewers alike * Truly an essential publication for anyone in any field of the life sciences

Author : P. F. Knowles,Derek Marsh,H. W. E. Rattle
Publisher : Wiley-Interscience
Page : 364 pages
File Size : 44,9 Mb
Release : 1976
Category : Biomolecules
ISBN : UOM:39015000834385

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Magnetic Resonance of Biomolecules by P. F. Knowles,Derek Marsh,H. W. E. Rattle Pdf

Author : A.Joshua Wand
Publisher : Academic Press
Page : 440 pages
File Size : 41,5 Mb
Release : 2019-01-03
Category : Science
ISBN : 9780128138618

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Biological NMR by A.Joshua Wand Pdf

Biological NMR, Part A, the latest release in the Methods of Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Protein methyl labeling, Membrane protein expression – yeast, Protein aromatic labeling, His-tag/Metal contamination, Bicelles, nanodiscs and micelles MP host, PTM – phosphorylation, PTM – lipidation, Screening platform for receptor-ligand discovery Solution Spectroscopy, Large protein strategies, NUS data collection/analysis, F19 incl. hydration, ODNP - hydration, Reverse micelle - Hydration Solid State Spectroscopy, SS NMR membrane proteins, SS NMR soluble/aggregate proteins, SS DNP - general, SS NMR nucleic acids, Structure determination and computer analysis, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods of Enzymology series Updated release includes the latest information on the Biological NMR

Author : S.K. Sarkar
Publisher : Elsevier
Page : 387 pages
File Size : 41,8 Mb
Release : 1996-12-04
Category : Science
ISBN : 0080537596

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NMR Spectroscopy and its Application to Biomedical Research by S.K. Sarkar Pdf

NMR has become the most diverse spectroscopic tool available to date in biomedical research. It is now routinely used to study biomolecular structure and dynamics particularly as a result of recent developments of a cascade of highly sophisticated multidimensional NMR pulse sequences, and of advances in genetic engineering to produce biomolecules, uniformly or selectively enriched with 13C, 15N and 2H. Features of this book: • Provides an up-to-date treatment of NMR techniques and their application to problems of biomedical interest • Most refined multidimensional pulse sequences including the basic aspects are covered by leading NMR spectroscopists. The book will be useful to NMR spectroscopists, biochemists, and to molecular biologists interested in the use of NMR techniques for solving biological problems.