Nonlinear Dynamic Modeling Of Physiological Systems

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Nonlinear Dynamic Modeling of Physiological Systems

Professor Vasilis Z. Marmarelis
Nonlinear Dynamic Modeling of Physiological Systems Book PDF

Author : Professor Vasilis Z. Marmarelis
Publisher : John Wiley & Sons
Page : 564 pages
File Size : 44,5 Mb
Release : 2004-09-03
Category : Medical
ISBN : 0471469602

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Nonlinear Dynamic Modeling of Physiological Systems by Professor Vasilis Z. Marmarelis Pdf

The study of nonlinearities in physiology has been hindered by the lack of effective ways to obtain nonlinear dynamic models from stimulus-response data in a practical context. A considerable body of knowledge has accumulated over the last thirty years in this area of research. This book summarizes that progress, and details the most recent methodologies that offer practical solutions to this daunting problem. Implementation and application are discussed, and examples are provided using both synthetic and actual experimental data. This essential study of nonlinearities in physiology apprises researchers and students of the latest findings and techniques in the field.

Nonlinear Dynamic Modeling of Physiological Systems

Vasilis Z. Marmarelis
Nonlinear Dynamic Modeling of Physiological Systems Book PDF

Author : Vasilis Z. Marmarelis
Publisher : IEEE
Page : 400 pages
File Size : 48,5 Mb
Release : 2004-12-09
Category : Medical
ISBN : 0471679364

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Nonlinear Dynamic Modeling of Physiological Systems by Vasilis Z. Marmarelis Pdf

A practical approach to obtaining nonlinear dynamic models from stimulus-response dataNonlinear modeling of physiological systems from stimulus-response data is a long-standing problem that has substantial implications for many scientific fields and associated technologies. These disciplines include biomedical engineering, signal processing, neural networks, medical imaging, and robotics and automation. Addressing the needs of a broad spectrum of scientific and engineering researchers, this book presents practicable, yet mathematically rigorous methodologies for constructing dynamic models of physiological systems. Nonlinear Dynamic Modeling of Physiological Systems provides the most comprehensive treatment of the subject to date. Starting with the mathematical background upon which these methodologies are built, the book presents the methodologies that have been developed and used over the past thirty years. The text discusses implementation and computational issues and gives illustrative examples using both synthetic and experimental data. The author discusses the various modeling approaches-nonparametric, including the Volterra and Wiener models; parametric; modular; and connectionist-and clearly identifies their comparative advantages and disadvantages along with the key criteria that must guide successful practical application. Selected applications covered include neural and sensory systems, cardiovascular and renal systems, and endocrine and metabolic systems. This lucid and comprehensive text is a valuable reference and guide for the community of scientists and engineers who wish to develop and apply the skills of nonlinear modeling to physiological systems.

Identification of Nonlinear Physiological Systems

David T. Westwick,Robert E. Kearney
Identification of Nonlinear Physiological Systems Book PDF

Author : David T. Westwick,Robert E. Kearney
Publisher : John Wiley & Sons
Page : 284 pages
File Size : 40,5 Mb
Release : 2003-08-28
Category : Technology & Engineering
ISBN : 0471274569

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Identification of Nonlinear Physiological Systems by David T. Westwick,Robert E. Kearney Pdf

Significant advances have been made in the field since the previous classic texts were written. This text brings the available knowledge up to date. * Enables the reader to use a wide variety of nonlinear system identification techniques. * Offers a thorough treatment of the underlying theory. * Provides a MATLAB toolbox containing implementation of the latest identification methods together with an extensive set of problems using realistic data sets.

Advanced Methods of Physiological System Modeling

V.Z. Marmarelis
Advanced Methods of Physiological System Modeling Book PDF

Author : V.Z. Marmarelis
Publisher : Springer Science & Business Media
Page : 276 pages
File Size : 47,9 Mb
Release : 2013-06-29
Category : Technology & Engineering
ISBN : 9781475790245

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Advanced Methods of Physiological System Modeling by V.Z. Marmarelis Pdf

This volume is the third in a series entitled" Advanced Methods of Physiological System Modeling" and the fifth in a series of research volumes published by Plenum under the sponsorship of the Biomedical Simulations Resource (BMSR) at the Uni versity of Southern California in the context of dissemination activities supported by the Biomedical Research Technology Program of the National Center for Research Resources at the National Institutes of Health under Grant No. P41 RR-OI861. These volumes are edited by BMSR principal scientists and report on recent research de velopments in the area of physiological systems modeling, as well as on advanced methods for analysis of physiological signals and data. As in the previous two volumes of this series, the work reported herein is con cerned with the development of advanced modeling methodologies and their novel application to problems of biomedical interest, with emphasis on nonlinear aspects of physiological function. The term "advanced methodologies" is used to indicate that the scope of this work extends beyond the ordinary type of analysis, which is confined traditionally to the linear domain. As the importance of nonlinearities in understanding the complex mechanisms of physiological function is increasingly recognized, the need for effective and practical modeling methodologies that address the issue of nonlinear dynamics in life sciences becomes more and more pressing.

Nonlinear Dynamics in Physiology and Medicine

Anne Beuter,Leon Glass,Michael C. Mackey,Michele S. Titcombe
Nonlinear Dynamics in Physiology and Medicine Book PDF

Author : Anne Beuter,Leon Glass,Michael C. Mackey,Michele S. Titcombe
Publisher : Springer Science & Business Media
Page : 452 pages
File Size : 46,5 Mb
Release : 2013-06-05
Category : Mathematics
ISBN : 9780387216409

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Nonlinear Dynamics in Physiology and Medicine by Anne Beuter,Leon Glass,Michael C. Mackey,Michele S. Titcombe Pdf

Introduces concepts from nonlinear dynamics using an almost exclusively biological setting for motivation, and includes examples of how these concepts are used in experimental investigations of biological and physiological systems. One novel feature of the book is the inclusion of classroom-tested computer exercises. This book will appeal to students and researchers working in the natural and physical sciences wanting to learn about physiological systems from a mathematical perspective.

Nonlinear Dynamics in Physiology

Mark Shelhamer
Nonlinear Dynamics in Physiology Book PDF

Author : Mark Shelhamer
Publisher : World Scientific
Page : 367 pages
File Size : 49,7 Mb
Release : 2007
Category : Science
ISBN : 9789812700292

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Nonlinear Dynamics in Physiology by Mark Shelhamer Pdf

This book provides a compilation of mathematical-computational tools that are used to analyze experimental data. The techniques presented are those that have been most widely and successfully applied to the analysis of physiological systems, and address issues such as randomness, determinism, dimension, and nonlinearity. In addition to bringing together the most useful methods, sufficient mathematical background is provided to enable non-specialists to understand and apply the computational techniques. Thus, the material will be useful to life-science investigators on several levels, from physiologists to bioengineer.Initial chapters present background material on dynamic systems, statistics, and linear system analysis. Each computational technique is demonstrated with examples drawn from physiology, and several chapters present case studies from oculomotor control, neuroscience, cardiology, psychology, and epidemiology. Throughout the text, historical notes give a sense of the development of the field and provide a perspective on how the techniques were developed and where they might lead. The overall approach is based largely on the analysis of trajectories in the state space, with emphasis on time-delay reconstruction of state-space trajectories. The goal of the book is to enable readers to apply these methods to their own research.

Advanced Methods of Physiological System Modeling

V.Z. Marmarelis
Advanced Methods of Physiological System Modeling Book PDF

Author : V.Z. Marmarelis
Publisher : Springer Science & Business Media
Page : 301 pages
File Size : 55,6 Mb
Release : 2012-12-06
Category : Technology & Engineering
ISBN : 9781461397892

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Advanced Methods of Physiological System Modeling by V.Z. Marmarelis Pdf

This volume is the second in a series of publications sponsored by the Biomedical Simulations Resource (BMSR) at the University of Southern California that report on recent research developments in the area of physiological systems modeling and anal ysis of physiological signals. As in the first volume of this series, the work reported herein is concerned with the development of advanced methodologies and their novel application to problems of biomedical interest, with emphasis on nonlinear aspects of physiological function. The term "advanced methodologies" is used to indicate that the scope of this work extends beyond the ordinary type of analysis used by most investigators in this area, which is confined primarily in the linear domain. As the im portance of nonlinearities in understanding the complex mechanisms of physiological function is increasingly recognized, the need for effective and practical methodolo gies that address the issue of nonlinear dynamics in life sciences becomes more and more pressing. The publication of these volumes and the workshops, organized by the BMSR on the same subject, are two key activities in our efforts to promote and intensify research in this area, foster interaction and collaboration among interested investigators, and disseminate recent results throughout the biomedical community.

Biomedical Engineering Fundamentals

Joseph D. Bronzino,Donald R. Peterson
Biomedical Engineering Fundamentals Book PDF

Author : Joseph D. Bronzino,Donald R. Peterson
Publisher : CRC Press
Page : 1570 pages
File Size : 53,9 Mb
Release : 2006-04-14
Category : Medical
ISBN : 9781420003857

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Biomedical Engineering Fundamentals by Joseph D. Bronzino,Donald R. Peterson Pdf

Over the last century,medicine has come out of theblack bag and emerged as one of the most dynamic and advanced fields of development in science and technology. Today, biomedical engineering plays a critical role in patient diagnosis, care, and rehabilitation. As such, the field encompasses a wide range of disciplines, from biology and physiolog

Physiological Control Systems

Michael C. K. Khoo
Physiological Control Systems Book PDF

Author : Michael C. K. Khoo
Publisher : John Wiley & Sons
Page : 456 pages
File Size : 51,5 Mb
Release : 2018-04-12
Category : Science
ISBN : 9781119058793

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Physiological Control Systems by Michael C. K. Khoo Pdf

A guide to common control principles and how they are used to characterize a variety of physiological mechanisms The second edition of Physiological Control Systems offers an updated and comprehensive resource that reviews the fundamental concepts of classical control theory and how engineering methodology can be applied to obtain a quantitative understanding of physiological systems. The revised text also contains more advanced topics that feature applications to physiology of nonlinear dynamics, parameter estimation methods, and adaptive estimation and control. The author—a noted expert in the field—includes a wealth of worked examples that illustrate key concepts and methodology and offers in-depth analyses of selected physiological control models that highlight the topics presented. The author discusses the most noteworthy developments in system identification, optimal control, and nonlinear dynamical analysis and targets recent bioengineering advances. Designed to be a practical resource, the text includes guided experiments with simulation models (using Simulink/Matlab). Physiological Control Systems focuses on common control principles that can be used to characterize a broad variety of physiological mechanisms. This revised resource: Offers new sections that explore identification of nonlinear and time-varying systems, and provide the background for understanding the link between continuous-time and discrete-time dynamic models Presents helpful, hands-on experimentation with computer simulation models Contains fully updated problems and exercises at the end of each chapter Written for biomedical engineering students and biomedical scientists, Physiological Control Systems, offers an updated edition of this key resource for understanding classical control theory and its application to physiological systems. It also contains contemporary topics and methodologies that shape bioengineering research today.

Engineering Approaches to Study Cardiovascular Physiology: Modeling, Estimation, and Signal Processing

Riccardo Barbieri,Zhe Chen
Engineering Approaches to Study Cardiovascular Physiology Modeling Estimation and Signal Processing Book PDF

Author : Riccardo Barbieri,Zhe Chen
Publisher : Frontiers E-books
Page : 136 pages
File Size : 53,8 Mb
Release : 2024-06-30
Category : Electronic
ISBN : 9782889190799

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Engineering Approaches to Study Cardiovascular Physiology: Modeling, Estimation, and Signal Processing by Riccardo Barbieri,Zhe Chen Pdf

With cardiovascular diseases being one of the main causes of death in the world, quantitative modeling, assessment and monitoring of the cardiovascular control system plays a critical role in bringing important breakthroughs to cardiovascular care. Quantification of cardiovascular physiology and its control dynamics from physiological recordings and by use of mathematical models and algorithms has been proved to be of important value in understanding the causes of cardiovascular diseases and assisting the prognostic or diagnostic process. Nowadays, development of new recording technologies (e.g., electrophysiology, imaging, ultrasound, etc) has enabled us to improve and expand acquisition of a wide spectrum of physiological measures related to cardiovascular control. An emerging challenge is to process and interpret such increasing amount of information by using state-of-the-art approaches in systems modeling, estimation and control, and signal processing, which would lead to further insightful scientific findings. In particular, multi-disciplinary engineering-empowered approaches of studying cardiovascular systems would greatly deepen our understanding of cardiovascular functions (e.g., heart rate variability, baroreflex sensitivity) and autonomic control, as it would also improve the knowledge about heart pathology, cardiovascular rehabilitation and therapy. Meanwhile, developing cardiovascular biomedical devices or heart-machine interface for either clinical monitoring or rehabilitation purpose is of greater and greater interest for both scientific advancement and potential medical benefits. This Research Topic will bring together established experts whose areas of research cover a wide range of studies and applications. Contributions include but are not limited to state-of-the-art modeling methodologies, algorithmic development in signal processing and estimation, as well as applications in cardiovascular rehabilitation, and clinical monitoring. The Research Topic will consider both invited reviews and original research.

Assessing Complexity in Physiological Systems through Biomedical Signals Analysis

Paolo Castiglioni,Luca Faes,Gaetano Valenza
Assessing Complexity in Physiological Systems through Biomedical Signals Analysis Book PDF

Author : Paolo Castiglioni,Luca Faes,Gaetano Valenza
Publisher : MDPI
Page : 296 pages
File Size : 55,5 Mb
Release : 2021-03-02
Category : Mathematics
ISBN : 9783039433681

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Assessing Complexity in Physiological Systems through Biomedical Signals Analysis by Paolo Castiglioni,Luca Faes,Gaetano Valenza Pdf

Complexity is a ubiquitous phenomenon in physiology that allows living systems to adapt to external perturbations. Fractal structures, self-organization, nonlinearity, interactions at different scales, and interconnections among systems through anatomical and functional networks, may originate complexity. Biomedical signals from physiological systems may carry information about the system complexity useful to identify physiological states, monitor health, and predict pathological events. Therefore, complexity analysis of biomedical signals is a rapidly evolving field aimed at extracting information on the physiological systems. This book consists of 16 contributions from authors with a strong scientific background in biomedical signals analysis. It includes reviews on the state-of-the-art of complexity studies in specific medical applications, new methods to improve complexity quantifiers, and novel complexity analyses in physiological or clinical scenarios. It presents a wide spectrum of methods investigating the entropic properties, multifractal structure, self-organized criticality, and information dynamics of biomedical signals touching upon three physiological areas: the cardiovascular system, the central nervous system, the heart-brain interactions. The book is aimed at experienced researchers in signal analysis and presents the latest trends in the complexity methods in physiology and medicine with the hope of inspiring future works advancing this fascinating area of research.

Introduction to Modeling in Physiology and Medicine

Claudio Cobelli,Ewart Carson
Introduction to Modeling in Physiology and Medicine Book PDF

Author : Claudio Cobelli,Ewart Carson
Publisher : Academic Press
Page : 384 pages
File Size : 54,6 Mb
Release : 2019-08-01
Category : Computers
ISBN : 9780128158050

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Introduction to Modeling in Physiology and Medicine by Claudio Cobelli,Ewart Carson Pdf

Introduction to Modeling in Physiology and Medicine, Second Edition, develops a clear understanding of the fundamental principles of good modeling methodology. Sections show how to create valid mathematical models that are fit for a range of purposes. These models are supported by detailed explanation, extensive case studies, examples and applications. This updated edition includes clearer guidance on the mathematical prerequisites needed to achieve the maximum benefit from the material, a greater detail regarding basic approaches to modeling, and discussions on non-linear and stochastic modeling. The range of case study material has been substantially extended, with examples drawn from recent research experience. Key examples include a cellular model of insulin secretion and its extension to the whole-body level, a model of insulin action during a meal/oral glucose tolerance test, a large-scale simulation model of type 1 diabetes and its use in in silico clinical trials and drug trials. Covers the underlying principles of good quantitative modeling methodology, with applied biomedical engineering and bioscience examples to ensure relevance to students, current research and clinical practice Includes modeling data, modeling systems, linear and non-linear systems, model identification, parametric and non-parametric models, and model validation Presents clear, step-by-step working plus examples and extensive case studies that relate concepts to real world applications Provides end-of-chapter exercises and assignments to reinforce learning

Molecular, Cellular, and Tissue Engineering

Joseph D. Bronzino,Donald R. Peterson
Molecular Cellular and Tissue Engineering Book PDF

Author : Joseph D. Bronzino,Donald R. Peterson
Publisher : CRC Press
Page : 1891 pages
File Size : 55,5 Mb
Release : 2018-10-08
Category : Medical
ISBN : 9781439825310

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Molecular, Cellular, and Tissue Engineering by Joseph D. Bronzino,Donald R. Peterson Pdf

Known as the bible of biomedical engineering, The Biomedical Engineering Handbook, Fourth Edition, sets the standard against which all other references of this nature are measured. As such, it has served as a major resource for both skilled professionals and novices to biomedical engineering. Molecular, Cellular, and Tissue Engineering, the fourth volume of the handbook, presents material from respected scientists with diverse backgrounds in molecular biology, transport phenomena, physiological modeling, tissue engineering, stem cells, drug delivery systems, artificial organs, and personalized medicine. More than three dozen specific topics are examined, including DNA vaccines, biomimetic systems, cardiovascular dynamics, biomaterial scaffolds, cell mechanobiology, synthetic biomaterials, pluripotent stem cells, hematopoietic stem cells, mesenchymal stem cells, nanobiomaterials for tissue engineering, biomedical imaging of engineered tissues, gene therapy, noninvasive targeted protein and peptide drug delivery, cardiac valve prostheses, blood substitutes, artificial skin, molecular diagnostics in personalized medicine, and bioethics.

Intelligent Systems

Ricardo Cerri,Ronaldo C. Prati
Intelligent Systems Book PDF

Author : Ricardo Cerri,Ronaldo C. Prati
Publisher : Springer Nature
Page : 666 pages
File Size : 40,9 Mb
Release : 2020-10-15
Category : Computers
ISBN : 9783030613778

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Intelligent Systems by Ricardo Cerri,Ronaldo C. Prati Pdf

The two-volume set LNAI 12319 and 12320 constitutes the proceedings of the 9th Brazilian Conference on Intelligent Systems, BRACIS 2020, held in Rio Grande, Brazil, in October 2020. The total of 90 papers presented in these two volumes was carefully reviewed and selected from 228 submissions. The contributions are organized in the following topical section: Part I: Evolutionary computation, metaheuristics, constrains and search, combinatorial and numerical optimization; neural networks, deep learning and computer vision; and text mining and natural language processing. Part II: Agent and multi-agent systems, planning and reinforcement learning; knowledge representation, logic and fuzzy systems; machine learning and data mining; and multidisciplinary artificial and computational intelligence and applications. Due to the Corona pandemic BRACIS 2020 was held as a virtual event.

New Developments in Biomedical Engineering

Domenico Campolo
New Developments in Biomedical Engineering Book PDF

Author : Domenico Campolo
Publisher : BoD – Books on Demand
Page : 726 pages
File Size : 46,8 Mb
Release : 2010-01-01
Category : Medical
ISBN : 9789537619572

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New Developments in Biomedical Engineering by Domenico Campolo Pdf

Biomedical Engineering is a highly interdisciplinary and well established discipline spanning across engineering, medicine and biology. A single definition of Biomedical Engineering is hardly unanimously accepted but it is often easier to identify what activities are included in it. This volume collects works on recent advances in Biomedical Engineering and provides a bird-view on a very broad field, ranging from purely theoretical frameworks to clinical applications and from diagnosis to treatment.