Nonsegmented Negative Strand Viruses

Author : David H.L. Bishop
Publisher : Elsevier
Page : 591 pages
File Size : 52,8 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323145084

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Nonsegmented Negative Strand Viruses by David H.L. Bishop Pdf

Nonsegmented Negative Strand Viruses: Paramyxoviruses and Rhabdoviruses consists of papers presented at the Fifth International Symposium on Negative Strand Viruses, held at Hilton Head, S.C., on September 11-17, 1983.This book specifically contains papers on negative strand virus families with nonsegmented genomes, paramyxoviruses and rhabdoviruses. This reference shows the advances in the research of the two virus families, paramyxoviruses and rhabdoviruses. It also illuminates the various stages in the strategy of negative strand virus infections, including adsorption, penetration, mRNA transcription, translation, RNA replication, morphogenesis, and virus release. The biology of virus infection and host response are also addressed.

Author : Yoshihiro Kawaoka
Publisher : Springer Science & Business Media
Page : 354 pages
File Size : 50,5 Mb
Release : 2013-04-17
Category : Medical
ISBN : 9783662060995

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Biology of Negative Strand RNA Viruses: The Power of Reverse Genetics by Yoshihiro Kawaoka Pdf

Negative-strand RNA viruses, so named because of the polarity of their genomic RNA to mRNA, include important human and non-human pathogens. This volume covers major advances in reverse genetics techniques over the past decade, state-of-the-art basic science and the clinical implications of experimental findings. This should rekindle interest in negative-strand RNA viruses among readers, including those in other disciplines, leading to further progress in understanding these important viruses and in developing effective measures of control.

Author : Ming Luo
Publisher : World Scientific
Page : 323 pages
File Size : 54,6 Mb
Release : 2011
Category : Science
ISBN : 9789814317221

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Negative Strand RNA Virus by Ming Luo Pdf

Negative strand RNA viruses have a unique mechanism of replication. Their genome is a single strand RNA that has to be transcribed as soon as the virus enters the host in order to carry out viral replication. As a result, a viral-specific RNA polymerase is packaged in the virion and is ready for transcription after virus entry. This novel replication mechanism dictates the assembly and RNA synthesis of negative strand RNA viruses. In recent years, many discoveries have been made with regard to the entry, replication and assembly of this class of viruses. This book will present updated coverage of the fundamental knowledge about negative strand RNA viruses.

Author : Susanne Modrow,Dietrich Falke,Uwe Truyen,Hermann Schätzl
Publisher : Springer
Page : 0 pages
File Size : 41,9 Mb
Release : 2013-09-18
Category : Science
ISBN : 3642207170

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Molecular Virology by Susanne Modrow,Dietrich Falke,Uwe Truyen,Hermann Schätzl Pdf

The book gives a comprehensive overview on the knowledge of virus infection relevant for humans and animals. For each virus family the molecular details of the virus particle and the viral replication cycle are described. In the case of virus types with relevance for human and/or animal health the data on molecular biology, genetics and virus-cell interaction are combined with those concerning, pathogenesis, epidemiology, clinics, prevention and therapy.

Author : Satya Prakash Gupta
Publisher : Academic Press
Page : 496 pages
File Size : 42,7 Mb
Release : 2018-10-29
Category : Science
ISBN : 9780128154236

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Viral Polymerases by Satya Prakash Gupta Pdf

Viral Polymerases: Structures, Functions and Roles as Antiviral Drug Targets presents in-depth study information on the structure and functions of polymerases and their roles in the lifecycle of viruses, and as drug targets. Viral polymerases constitute a vital component in the lifecycle of many viruses, such as human immunodeficiency virus (HIV), hepatitis viruses, influenza virus, and several others. They are essentially required for the replication of viruses. Thus, the polymerases that can be found in viruses (called viral polymerases) represent favorable targets for the design and development of antiviral drugs. Provides comprehensive, state-of-the-art coverage on virus infections, the virus lifecycle, and mechanisms of polymerase inhibition Analyzes the structure-activity relationships of inhibitors of each viral polymerase Presents a consistent and comprehensive coverage of all aspects of viral polymerases, including structure, function and their role as antiviral drug targets

Author : Harinder P.S. Makkar,Gerrit J. Viljoen
Publisher : Springer Science & Business Media
Page : 787 pages
File Size : 51,9 Mb
Release : 2005-08-12
Category : Science
ISBN : 9781402033117

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Applications of Gene-Based Technologies for Improving Animal Production and Health in Developing Countries by Harinder P.S. Makkar,Gerrit J. Viljoen Pdf

Modern Biotechnology has potential for solving many problems associated with animal productivity and health and offers exciting opportunities for enhancing agricultural productivity. At present the focus is, however, on the issues and problems of significance for livestock producers in the developed world. In order to fully realize the benefits of this technology in developing countries, there is a need to identify, characterize and apply appropriate gene-based technologies for these regions. These proceedings present peer reviewed state-of-the-art papers describing the achievements in the areas of animal breeding and genetics, animal nutrition, animal health, and environment, ethics, safety, and regulatory aspects of gene-based technologies; achievements which could be realized using these modern scientific tools to maximise the benefits from the 'livestock revolution' that is taking place; and the constraints in the use of gene-based technologies and their specific research needs. This book will help in bridging the wide gap between developed and developing countries, in the development and use of gene-based technologies, and to elucidate the current and future roles of such technologies in the developing world. It is a good reference source for researchers, students and policy-makers alike.

Author : Arthur I. Vogel
Publisher : Unknown
Page : 1216 pages
File Size : 44,5 Mb
Release : 1961
Category : Electronic
ISBN : 0121835014

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Quantitative Inorganic Analysis Including Elementary Instrumental Analysis by Arthur I. Vogel Pdf

Author : Muhammad Munir
Publisher : Springer
Page : 0 pages
File Size : 50,6 Mb
Release : 2016-08-23
Category : Medical
ISBN : 3662523086

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Peste des Petits Ruminants Virus by Muhammad Munir Pdf

This book offers a timely and comprehensive review of essential research on Peste des Petits Ruminants Virus (PPRV), ranging from its historical distribution, molecular epidemiology, genome structure, viral proteins, immunity, viral pathogenesis, clinical and molecular diagnosis to advances in vaccine developments and future challenges. PPRV, a Rinderpest-like virus, is the causative agent of one of the most rapidly emerging viral diseases among domestic small ruminants, and the host spectrum has now been expanded to wild small ruminants and camels. With the global eradication of the first livestock disease, Rinderpest, attention is now turning to repeating the procedure for PPR. Each of the book’s 13 chapters is dedicated to a specific topic, providing up-to-date literature and discussions by renowned scientists who have made seminal contributions in their respective fields of expertise. Special emphasis has been placed on the analysis of different global efforts to eradicate PPR. This book offers a valuable reference source for virologists, field veterinarians, infection and molecular biologists, immunologists, scientists in related fields and veterinary school libraries.

Author : O.-R. Kaaden,W. Eichhorn,C.-P. Czerny
Publisher : Springer Science & Business Media
Page : 307 pages
File Size : 48,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783709193006

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Unconventional Agents and Unclassified Viruses by O.-R. Kaaden,W. Eichhorn,C.-P. Czerny Pdf

Among unconventional agents and unclassified viruses the contributions to this volume focused on prion-related diseases, with special emphasis on bovine spongiform encephalopathy and human spongiform encephalopathies, and Borna disease virus, an agent known since long time to be pathogenic for horses and sheep, which is now discussed as a potential pathogen for humans. Additionally, the volume contains articles about newly discovered viruses like porcine respiratory and reproductive syndrome virus and viruses that are classified only provisionally like African swine fever virus, hepatitis C and E viruses, or the arteriviruses.

Author : Yoshiyuki Nagai
Publisher : Springer Science & Business Media
Page : 218 pages
File Size : 45,5 Mb
Release : 2014-01-31
Category : Medical
ISBN : 9784431545569

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Sendai Virus Vector by Yoshiyuki Nagai Pdf

Sendai virus (SeV) is not just a mouse pathogen but is evolving into a cutting-edge component of biotechnology. SeV reverse genetics originating from a pure academic need to settle long-held questions in the biology and pathogenicity of nonsegmented negative strand RNA viruses (Mononegavirales) is about to bear the impressive fruit of multipurpose cytoplasmic (non-integrating) RNA vectors. This book brings together in one source the SeV biology revealed by conventional approaches and reverse genetics, the methods to construct the first-generation SeV vector and to generate safer versions, and the applications in medical settings that have left or are about to leave the laboratory bench. The applications, which already are diverse and have high medical impact, include use as vaccine vectors against AIDS and respiratory virus infections, creation of BioKnife to resect malignant tumors, induction of “footprint (transgene) free” pluripotent stem cells, and gene therapy for peripheral arterial disease. These achievements—which are just a few of many examples—were attainable only after rigorously incorporating the rich knowledge of SeV biology that has accumulated during the several decades since the discovery of the virus. Application of SeV vector is certain to expand greatly because of its extremely high performance in transgene expression and its remarkable target cell breadth.

Author : Ellen G. Strauss,James H. Strauss
Publisher : Elsevier
Page : 480 pages
File Size : 47,8 Mb
Release : 2007-09-21
Category : Science
ISBN : 0080553168

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Viruses and Human Disease by Ellen G. Strauss,James H. Strauss Pdf

Completely revised and updated, the new edition of this groundbreaking text integrates basic virology with pathophysiological conditions to examine the connection between virology and human disease. Most virology textbooks focus on the molecular biology involved without adequate reference to physiology. This text focuses on viruses that infect humans, domestic animals and vertebrates and is based on extensive course notes from James Strauss’ virology class at the California Institute of Technology taught for over 30 years. Expertly depicting in color the molecular structure and replication of each virus, it provides an excellent overview for students and professionals interested in viruses as agents of human disease. Includes over 30% new material - virtually all of the figures and tables have been redrawn to include the latest information and the text has been extensively rewritten to include the most up-to-date information Includes a new chapter on emerging and reemerging viral diseases such as avian flu, SARS, the spread of West Nile virus across America, and the continuing spread of Nipah virus in Southeast Asia Further reading sections at the end of each chapter make it easy find key references World maps depicting the current distribution of existing and newly emerging viruses are also incorporated into the text

Author : J. Robin Harris,David Bhella
Publisher : Springer
Page : 442 pages
File Size : 45,6 Mb
Release : 2018-06-13
Category : Science
ISBN : 9789811084560

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Virus Protein and Nucleoprotein Complexes by J. Robin Harris,David Bhella Pdf

The Subcellular Biochemistry series has recently embarked upon an almost encyclopaedic coverage of topics relating to the structure and function of macromolecular complexes (Volumes 82, 83 and 87). The present multi-author text covers numerous aspects of current research into molecular virology, with emphasis upon viral protein and nucleoprotein structure and function. Structural data from cryo-electron microscopy and X-ray crystallography is displayed throughout the book. The 17 chapters in the book cover diverse interesting topics, all currently under investigation, contributed by authors who are active actively involved in present-day research. Whilst structural aspects predominate, there is much consideration of the structure-function relationship. In addition, the book correlates with and extends from Volume 68 of the series “Structure and Physics of Viruses: An Integrated Textbook”. This book is directed primarily at professionals that work in the broad field of Structural Biology and will be of particular interest to Structural Virologists. The editors, David Bhella and Robin Harris, have much experience in virology and protein structure, respectively. Dr Bhella is Director of the Scottish Macromolecular Imaging Centre. Professor Robin Harris is the long-standing Series Editor of the Subcellular Biochemistry series. He has edited and contributed to several books in the series.

Author : Monique Dubois-Dalcq,Kathryn V. Holmes,Bernard Rentier
Publisher : Springer Science & Business Media
Page : 249 pages
File Size : 44,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783709187562

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Assembly of Enveloped RNA Viruses by Monique Dubois-Dalcq,Kathryn V. Holmes,Bernard Rentier Pdf

This book is a collection of critical reviews about a diverse group of virus families with two features in common: the stable repository of genetic information in each virus is RNA, and each virus modifies and appropriates a particular patch of the eukaryotic cell membrane system to complete its structure. The reviews take the reader from the level of virus genome structure and expression through the quaternary interactions between virus-specified elements and cellular components that cooperate to produce virus particles. There are spectacular illustrations in this volume, but it is much more than a picture gallery. Reading widely in this book can be an effective antidote to overspecialization: in these pages, you are likely to learn much about viruses and about cells that you didn't know before; you'll discover illuminating parallels between diverse virus families; you'll come away with a sharpened awareness of important things that are still to be learned. Memphis, Tenn. , Summer 1984 David W. Kingsbury Preface This book was written at the suggestion of Dr. David W. Kingsbury made at a work shop on viruses organized by the Multiple Sclerosis Society in Aspen, Colorado, U. S. A. , three years ago. Originally, we had thought to focus on the morphological aspects of viral assembly. Later, during our discussions on the process of budding of enveloped RNA viruses, it became evident that we should include biochemical data in our review and correlate them with the structural aspects of virus maturation.

Author : David H. L. Bishop
Publisher : Unknown
Page : 560 pages
File Size : 49,7 Mb
Release : 1984
Category : Electronic
ISBN : 0121024806

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Nonsegmented Negative Strand Viruses by David H. L. Bishop Pdf

Author : Chundi L. Mandahar
Publisher : Springer Science & Business Media
Page : 353 pages
File Size : 47,7 Mb
Release : 2006-09-05
Category : Science
ISBN : 9781402047251

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Multiplication of RNA Plant Viruses by Chundi L. Mandahar Pdf

Biochemical studies on plant virus RNA replication have advanced considerably since 2000, primarily because of new genetic, molecular, biochemical, and enzymatic studies. This book generates understanding of multiplication of plus-sense RNA plant viruses, especially at molecular level. Certain virus-encoded essential proteins, nucleotide sequence motifs, and RNA secondary structures are central to virus RNA replication, which has a number of stages. Each is a complex phenomenon requiring specific factors and conditions.