Numerical Methods And Advanced Simulation In Biomechanics And Biological Processes

Author : Miguel Cerrolaza,Sandra Shefelbine,Diego Garzón-Alvarado
Publisher : Academic Press
Page : 454 pages
File Size : 42,5 Mb
Release : 2017-10-17
Category : Technology & Engineering
ISBN : 9780128117194

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Numerical Methods and Advanced Simulation in Biomechanics and Biological Processes by Miguel Cerrolaza,Sandra Shefelbine,Diego Garzón-Alvarado Pdf

Numerical Methods and Advanced Simulation in Biomechanics and Biological Processes covers new and exciting modeling methods to help bioengineers tackle problems for which the Finite Element Method is not appropriate. The book covers a wide range of important subjects in the field of numerical methods applied to biomechanics, including bone biomechanics, tissue and cell mechanics, 3D printing, computer assisted surgery and fluid dynamics. Modeling strategies, technology and approaches are continuously evolving as the knowledge of biological processes increases. Both theory and applications are covered, making this an ideal book for researchers, students and R&D professionals. Provides non-conventional analysis methods for modeling Covers the Discrete Element Method (DEM), Particle Methods (PM), MessLess and MeshFree Methods (MLMF), Agent-Based Methods (ABM), Lattice-Boltzmann Methods (LBM) and Boundary Integral Methods (BIM) Includes contributions from several world renowned experts in their fields Compares pros and cons of each method to help you decide which method is most applicable to solving specific problems

Author : C. A. Duque-Daza,D. A. Garzón-Alvarado,M. Cerrolaza,D. L. Linero-Segrera
Publisher : Cambridge Scholars Publishing
Page : 349 pages
File Size : 48,9 Mb
Release : 2023-07-25
Category : Medical
ISBN : 9781527528550

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Numerical Methods and Modelling Methodologies in Computational Biomechanics by C. A. Duque-Daza,D. A. Garzón-Alvarado,M. Cerrolaza,D. L. Linero-Segrera Pdf

This book provides a description of the use of engineering simulation methods in a clear, direct and concise way, containing several relevant examples of biomechanics and biological processes analyzed with different numerical methods. It is oriented towards undergraduate and graduate students, academics, professionals, technicians and to all those interested in the use of simulation in computational biomechanics. The book begins with a review of the concepts of solid and fluid mechanics, followed by a description of engineering approximation methods such as the Finite Volume Method, the Finite Element Method and the Boundary Element Method. Then, several applications that usually appear in biomechanics modeling are presented and discussed, from the simulation of osseointegration to the simulation of lung airflow and the modeling of biological processes in intervertebral discs and mechanobiology. The book can be used as an educational tool in undergraduate courses and in introductory courses in graduate biology, medicine and engineering.

Author : Mariano Vázquez,Peter V. Coveney,Hernan Edgardo Grecco,Alfons Hoekstra,Bastien Chopard
Publisher : Frontiers Media SA
Page : 449 pages
File Size : 55,5 Mb
Release : 2019-04-04
Category : Electronic
ISBN : 9782889458172

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Advanced HPC-based Computational Modeling in Biomechanics and Systems Biology by Mariano Vázquez,Peter V. Coveney,Hernan Edgardo Grecco,Alfons Hoekstra,Bastien Chopard Pdf

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Author : Chief Editor- Biplab Auddya, Editor- Dr. Darshanam Vijaykumar, Advitya Khurana, Dr. S.Amutha, Dr. Kavita Jaidiya, Dr. Jayesh Manjrekar, Dr. L Malleswara Rao, Mr. Sugeet Sethi
Publisher : The Hill Publication
Page : 153 pages
File Size : 41,8 Mb
Release : 2023-09-14
Category : Antiques & Collectibles
ISBN : 9788196477639

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Research in Multidisciplinary Subjects (Volume- 5) by Chief Editor- Biplab Auddya, Editor- Dr. Darshanam Vijaykumar, Advitya Khurana, Dr. S.Amutha, Dr. Kavita Jaidiya, Dr. Jayesh Manjrekar, Dr. L Malleswara Rao, Mr. Sugeet Sethi Pdf

Author : Stilianos Louca
Publisher : Stilianos Louca
Page : 545 pages
File Size : 46,6 Mb
Release : 2023-06-07
Category : Mathematics
ISBN : 8210379456XXX

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Dynamical Modeling of Biological Systems by Stilianos Louca Pdf

This book introduces concepts and practical tools for dynamical mathematical modeling of biological systems. Dynamical models describe the behavior of a system over time as a result of internal feedback loops and external forcing, based on mathematically formulated dynamical laws, similarly to how Newton's laws describe the movement of celestial bodies. Dynamical models are increasingly popular in biology, as they tend to be more powerful than static regression models. This book is meant for undergraduate and graduate students in physics, applied mathematics and data science with an interest in biology, as well as students in biology with a strong interest in mathematical methods. The book covers deterministic models (for example differential equations), stochastic models (for example Markov chains and autoregressive models) and model-independent aspects of time series analysis. Plenty of examples and exercises are included, often taken or inspired from the scientific literature, and covering a broad range of topics such as neuroscience, cell biology, genetics, evolution, ecology, microbiology, physiology, epidemiology and conservation. The book delivers generic modeling techniques used across a wide range of situations in biology, and hence readers from other scientific disciplines will find that much of the material is also applicable in their own field. Proofs of most mathematical statements are included for the interested reader, but are not essential for a practical understanding of the material. The book introduces the popular scientific programming language MATLAB as a tool for simulating models, fitting models to data, and visualizing data and model predictions. The material taught is current as of MATLAB version 2022b. The material is taught in a sufficiently general way that also permits the use of alternative programming languages.

Author : Constantin Volosencu,Cheon Seoung Ryoo
Publisher : BoD – Books on Demand
Page : 268 pages
File Size : 52,6 Mb
Release : 2022-01-19
Category : Computers
ISBN : 9781839696831

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Simulation Modeling by Constantin Volosencu,Cheon Seoung Ryoo Pdf

The book presents some recent specialized works of a theoretical and practical nature in the field of simulation modeling, which is being addressed to a large number of specialists, mathematicians, doctors, engineers, economists, professors, and students. The book comprises 11 chapters that promote modern mathematical algorithms and simulation modeling techniques, in practical applications, in the following thematic areas: mathematics, biomedicine, systems of systems, materials science and engineering, energy systems, and economics. This project presents scientific papers and applications that emphasize the capabilities of simulation modeling methods, helping readers to understand the phenomena that take place in the real world, the conditions of their development, and their effects, at a high scientific and technical level. The authors have published work examples and case studies that resulted from their researches in the field. The readers get new solutions and answers to questions related to the emerging applications of simulation modeling and their advantages.

Author : Amit Gefen
Publisher : Academic Press
Page : 406 pages
File Size : 42,6 Mb
Release : 2019-11-05
Category : Science
ISBN : 9780128150283

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Innovations and Emerging Technologies in Wound Care by Amit Gefen Pdf

Innovations and Emerging Technologies in Wound Care is a pivotal book on the prevention and management of chronic and non-healing wounds. The book clearly presents the research and evidence that should be considered when planning care interventions to improve health related outcomes for patients. New and emerging technologies are discussed and identified, along with tactics on how they can be integrated into clinical practice. This book offers readers a bridge between biomedical engineering and medicine, with an emphasis on technological innovations. It includes contributions from engineers, scientists, clinicians and industry professionals. Users will find this resource to be a complete picture of the latest knowledge on the tolerance of human tissues to sustained mechanical and thermal loads that also provides a deeper understanding of the risk for onset and development of chronic wounds. Describes the state-of-knowledge in wound research, including tissue damage cascades and healing processes Covers all state-of-the-art technology in wound prevention, diagnosis, prognosis and treatment Discusses emerging research directions and future technology trends in the field of wound prevention and care Offers a bench-to-bedside exploration of the key issues that affect the practice of prevention and management of non-healing wounds

Author : Suvranu De,Farshid Guilak,Mohammad Mofrad
Publisher : Springer Science & Business Media
Page : 581 pages
File Size : 53,9 Mb
Release : 2010-03-10
Category : Technology & Engineering
ISBN : 9789048135752

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Computational Modeling in Biomechanics by Suvranu De,Farshid Guilak,Mohammad Mofrad Pdf

Availability of advanced computational technology has fundamentally altered the investigative paradigm in the field of biomechanics. Armed with sophisticated computational tools, researchers are seeking answers to fundamental questions by exploring complex biomechanical phenomena at the molecular, cellular, tissue and organ levels. The computational armamentarium includes such diverse tools as the ab initio quantum mechanical and molecular dynamics methods at the atomistic scales and the finite element, boundary element, meshfree as well as immersed boundary and lattice-Boltzmann methods at the continuum scales. Multiscale methods that link various scales are also being developed. While most applications require forward analysis, e.g., finding deformations and stresses as a result of loading, others involve determination of constitutive parameters based on tissue imaging and inverse analysis. This book provides a glimpse of the diverse and important roles that modern computational technology is playing in various areas of biomechanics including biofluids and mass transfer, cardiovascular mechanics, musculoskeletal mechanics, soft tissue mechanics, and biomolecular mechanics.

Author : Tobias Gleim ,Stephan Lange
Publisher : kassel university press GmbH
Page : 493 pages
File Size : 43,9 Mb
Release : 2019-09-04
Category : Technology & Engineering
ISBN : 9783737650939

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Proceedings of 8th GACM Colloquium on Computational Mechanics by Tobias Gleim ,Stephan Lange Pdf

This conference book contains papers presented at the 8th GACM Colloquium on Computational Mechanics for Young Scientists from Academia and Industry. The conference was held from August 28th – 30th, 2019 in Kassel, hosted by the Institute of Mechanics and Dynamics of the department for civil and environmental engineering and by the chair of Engineering Mechanics / Continuum Mechanics of the department for mechanical engineering of the University of Kassel. The aim of the conference is, to bring together young scientits who are engaged in academic and industrial research on Computational Mechanics and Computer Methods in Applied Sciences. It provides a plattform to present and discuss recent results from research efforts and industrial applications. In more than 150 presentations, given by young scientists, current scientific developments and advances in engineering practice in this field are presented and discussed. The contributions of the young researchers are supplemented by a poster session and plenary talks from four senior scientists from academia and industry as well as from the GACM Best PhD Award winners 2017 and 2018.

Author : Alexander Birbrair
Publisher : Academic Press
Page : 336 pages
File Size : 50,6 Mb
Release : 2021-03-31
Category : Science
ISBN : 9780128223260

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Recent Advances in iPSC Technology by Alexander Birbrair Pdf

The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology.Recent Advances in iPSC Technology, Volume 5 addresses the progress in induced pluripotent stem cells (iPSCs) technologies.Somatic cells can be reprogrammed into iPSCs by the expression of specific transcription factors. These cells are transforming biomedical research in the last 15 years. The volume teaches readers about current advances in the field. This book describes different technologies and strategies to use iPSCs for biological and clinical benefit. In recent years, remarkable progress has been made in the obtention of iPSCs and their differentiation into several cell types, tissues, and organs using state-of-the-art techniques. These advantages facilitated identification of key targets and definition of the molecular basis of several disorders. This volume will cover hot topics in the iPSC field, such as iPSCs for modeling the cardiovascular toxicities of anticancer therapies, iPSC differentiation through the lens of the noncoding genome, modeling of blood–brain barrier with iPSCs, mathematical modeling of iPSCs, iPSCs to study human brain evolution, selfrenewal in iPSCs, differences and similarities between iPSCs and embryonic stem cells, and more.The volume is written for researchers and scientists interested in stem cell therapy, cell biology, regenerative medicine, and organ transplantation and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of induced pluripotent stem cell technology, regenerative medicine, and therapeutics Covers the following topics: iPSCs for modeling the cardiovascular toxicities of anticancer therapies, iPSC differentiation through the lens of the non-coding genome, modeling of blood-brain barrier with iPSCs, mathematical modelling of iPSCs, iPSCs to study human brain evolution, self-renewal in iPSCs, differences and similarities between iPSCs and embryonic stem cells, and more Contributed by world-renown experts in the field

Author : Victor Malyshkin
Publisher : Springer
Page : 446 pages
File Size : 45,7 Mb
Release : 2019-08-01
Category : Computers
ISBN : 9783030256364

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Parallel Computing Technologies by Victor Malyshkin Pdf

This book constitutes the proceedings of the 15th International Conference on Parallel Computing Technologies, PaCT 2019, held in Almaty, Kazakhstan, in August 2019. The 24 full papers and 10 short papers presented were carefully reviewed and selected from 72 submissions. The papers are organized in topical sections on Programming Languages and Execution Environments; Methods and Tools for Parallel Solution of Large-Scale Problems; Data Processing; Cellular Automata; and Distributed Algorithms.

Author : José A. Sanz-Herrera
Publisher : MDPI
Page : 244 pages
File Size : 46,9 Mb
Release : 2020-05-27
Category : Medical
ISBN : 9783039289653

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Biomaterials for Bone Tissue Engineering by José A. Sanz-Herrera Pdf

Bone tissue engineering aims to develop artificial bone substitutes that partially or totally restore the natural regeneration capability of bone tissue lost under circumstances of injury, significant defects, or diseases such as osteoporosis. In this context, biomaterials are the keystone of the methodology. Biomaterials for bone tissue engineering have evolved from biocompatible materials that mimic the physical and chemical environment of bone tissue to a new generation of materials that actively interacts with the physiological environment, accelerating bone tissue growth. Mathematical modelling and simulation are important tools in the overall methodology. This book presents an overview of the current investigations and recent contributions in the field of bone tissue engineering. It includes several successful examples of multidisciplinary collaboration in this transversal area of research. The book is intended for students, researchers, and professionals of a number of disciplines, such as engineering, mathematics, physics, chemistry, biomedicine, biology, and veterinary. The book is composed of an editorial section and 16 original research papers authored by leading researchers of this discipline from different laboratories across the world

Author : Shaofan Li,Dong Qian
Publisher : John Wiley & Sons
Page : 480 pages
File Size : 47,8 Mb
Release : 2013-03-19
Category : Technology & Engineering
ISBN : 9781118402948

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Multiscale Simulations and Mechanics of Biological Materials by Shaofan Li,Dong Qian Pdf

Multiscale Simulations and Mechanics of BiologicalMaterials A compilation of recent developments in multiscalesimulation and computational biomaterials written by leadingspecialists in the field Presenting the latest developments in multiscale mechanics andmultiscale simulations, and offering a unique viewpoint onmultiscale modelling of biological materials, this book outlinesthe latest developments in computational biological materials fromatomistic and molecular scale simulation on DNA, proteins, andnano-particles, to meoscale soft matter modelling of cells, and tomacroscale soft tissue and blood vessel, and bone simulations.Traditionally, computational biomaterials researchers come frombiological chemistry and biomedical engineering, so this isprobably the first edited book to present work from these talentedcomputational mechanics researchers. The book has been written to honor Professor Wing Liu ofNorthwestern University, USA, who has made pioneering contributionsin multiscale simulation and computational biomaterial in specificsimulation of drag delivery at atomistic and molecular scale andcomputational cardiovascular fluid mechanics via immersed finiteelement method. Key features: Offers a unique interdisciplinary approach to multiscalebiomaterial modelling aimed at both accessible introductory andadvanced levels Presents a breadth of computational approaches for modellingbiological materials across multiple length scales (molecular towhole-tissue scale), including solid and fluid basedapproaches A companion website for supplementary materials plus links tocontributors’ websites (www.wiley.com/go/li/multiscale)

Author : Hua Li,Vadim Silberschmidt
Publisher : Woodhead Publishing
Page : 342 pages
File Size : 44,9 Mb
Release : 2022-08-18
Category : Technology & Engineering
ISBN : 9780081028636

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The Mechanics of Hydrogels by Hua Li,Vadim Silberschmidt Pdf

The Mechanics of Hydrogels: Mechanical Properties, Testing, and Applications offers readers a systematic description of the mechanical properties and characterizations of hydrogels. Practical topics such as manufacturing hydrogels with controlled mechanical properties and the mechanical testing of hydrogels are covered at length, as are areas such as inelastic and nonlinear deformation, rheological characterization, fracture and indentation testing, mechanical properties of cellularly responsive hydrogels, and more. Proper instrumentation and modeling techniques for measuring the mechanical properties of hydrogels are also explored. Links the mechanical and biological behaviors and applications of hydrogels Looks at the manufacturing and mechanical testing of hydrogels Discusses the design and use of hydrogels in a wide array of applications

Author : Russell Schwartz
Publisher : MIT Press
Page : 403 pages
File Size : 51,7 Mb
Release : 2008-07-25
Category : Science
ISBN : 9780262303392

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Biological Modeling and Simulation by Russell Schwartz Pdf

A practice-oriented survey of techniques for computational modeling and simulation suitable for a broad range of biological problems. There are many excellent computational biology resources now available for learning about methods that have been developed to address specific biological systems, but comparatively little attention has been paid to training aspiring computational biologists to handle new and unanticipated problems. This text is intended to fill that gap by teaching students how to reason about developing formal mathematical models of biological systems that are amenable to computational analysis. It collects in one place a selection of broadly useful models, algorithms, and theoretical analysis tools normally found scattered among many other disciplines. It thereby gives the aspiring student a bag of tricks that will serve him or her well in modeling problems drawn from numerous subfields of biology. These techniques are taught from the perspective of what the practitioner needs to know to use them effectively, supplemented with references for further reading on more advanced use of each method covered. The text, which grew out of a class taught at Carnegie Mellon University, covers models for optimization, simulation and sampling, and parameter tuning. These topics provide a general framework for learning how to formulate mathematical models of biological systems, what techniques are available to work with these models, and how to fit the models to particular systems. Their application is illustrated by many examples drawn from a variety of biological disciplines and several extended case studies that show how the methods described have been applied to real problems in biology.