Nusap A Novel Microtubule Associated Protein Involved In Mitotic Spindle Organization

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NuSAP, a Novel Microtubule-Associated Protein Involved in Mitotic Spindle Organization

Tim Raemaekers
NuSAP a Novel Microtubule Associated Protein Involved in Mitotic Spindle Organization Book PDF

Author : Tim Raemaekers
Publisher : Leuven University Press
Page : 140 pages
File Size : 53,6 Mb
Release : 2003-09
Category : Science
ISBN : 9058673030

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NuSAP, a Novel Microtubule-Associated Protein Involved in Mitotic Spindle Organization by Tim Raemaekers Pdf

"Vitamin D and bone, Linking the fields of vitamin D and bone with those of the nucleus and mitotic spindle, Nucleus structure and dynamics, Organization of the nucleus, Microtubules and associated proteins, Mitosis and spindle assembly, Control and mechanism of spindle formation and dynamics, Materials and methods, NuSAP, and novel MAP involved in spindle organization, NuSAP expression in cultured osteoblasts: regulation during development and by 1,25-dihydroxyvitamin D3, Analysis of NuSAP gene expression at the tissue level and chromosomal localization of human and mouse NuSAP, Developmentally regulated expression of NuSAP in the rat testis and mouse embryo, Chromosomal localization of human and mouse Nusap, General discussion and perspectives."

Ras Superfamily Small G Proteins: Biology and Mechanisms 2

Alfred Wittinghofer
Ras Superfamily Small G Proteins Biology and Mechanisms 2 Book PDF

Author : Alfred Wittinghofer
Publisher : Springer
Page : 299 pages
File Size : 51,8 Mb
Release : 2014-09-26
Category : Science
ISBN : 9783319077611

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Ras Superfamily Small G Proteins: Biology and Mechanisms 2 by Alfred Wittinghofer Pdf

This second of two volumes discusses subfamily proteins which function in molecular and vesicular transport mechanisms inside the cell. In this volume the focus lies on the Rab, Ran and Arf subfamily members. As in Volume 1, the book is written by international renowned scientists in the field of small G-proteins. In elaborate reviews, biochemistry, structure, function and G-protein - effector interactions are described. Together with Volume 1 this book provides an comprehensive state-of-the-art work on small G-proteins (GTPases). It is written for Graduates and Professors in Biochemistry and Cell Biology interested in the mechanism and function of small G-proteins but are extremely valuable for those who want to move into the field.

Proteins of the Nucleolus

Danton H O'Day,Andrew Catalano
Proteins of the Nucleolus Book PDF

Author : Danton H O'Day,Andrew Catalano
Publisher : Springer Science & Business Media
Page : 371 pages
File Size : 46,9 Mb
Release : 2013-02-26
Category : Science
ISBN : 9789400758186

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Proteins of the Nucleolus by Danton H O'Day,Andrew Catalano Pdf

This book contains 14 original review chapters each yielding new, exciting and intriguing data about the emerging understanding of nucleolar structure and function in normal, stressed and diseased cells. The goal of this work is to provide special insight into the nucleolus of the past, present and future, as well its regulation, translocation, and biomedical function. A multitude of topics are introduced and discussed in detail, including nucleologenesis, nucleolar architecture, nucleolar targeting, retention, anchoring, translocation, and the relationship between the nucleolus and cancer. This book also brings together work from several different species, from human to Drosophila to Dictyostelium and other eukaryotic microbes. The final chapter summarizes some of the issues brought up in the various chapters with a view to future research. This book supports the continued emergence of the nucleolus as a dynamic intranuclear region that oversees a vast diversity of events.

Index Medicus

Anonim
Index Medicus Book PDF

Author : Anonim
Publisher : Unknown
Page : 1666 pages
File Size : 44,7 Mb
Release : 2004
Category : Medicine
ISBN : MINN:31951P00992540S

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Index Medicus by Anonim Pdf

Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Biology-Driven Targeted Therapy of Pediatric Soft-Tissue and Bone Tumors: Current Opportunities and Future Challenges

Thomas G. P. Grünewald,Simone Fulda
Biology Driven Targeted Therapy of Pediatric Soft Tissue and Bone Tumors Current Opportunities and Future Challenges Book PDF

Author : Thomas G. P. Grünewald,Simone Fulda
Publisher : Frontiers Media SA
Page : 149 pages
File Size : 49,7 Mb
Release : 2016-04-05
Category : Cancer in children
ISBN : 9782889198191

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Biology-Driven Targeted Therapy of Pediatric Soft-Tissue and Bone Tumors: Current Opportunities and Future Challenges by Thomas G. P. Grünewald,Simone Fulda Pdf

Recent advances in the understanding of the biological basis of pediatric soft-tissue and bone tumors, especially owing to the advent of “omics” technologies, have led to an exponential increase in the current knowledge on the genetic and cellular patho-mechanisms that drive these diseases. This offers the unprecedented opportunity to develop and implement targeted therapies such as monoclonal antibodies, small molecules, oncolytic viruses, and immunotherapies in standard and/or personalized treatment regimens. However, to date only a few examples document a successful translation of discoveries from the bench to the bedside. Recent international expert congresses further emphasize the urgent need for a more rapid and especially more successful translational process. Hence, we strongly believe that a Frontiers Research Topic aiming at this aspect would fit just in time and be relevant for a broad readership. This Frontiers Research Topic intended to provide a platform for active and interdisciplinary discussion, to summarize current state-of-the-art knowledge on all basic research and translational aspects in pediatric soft-tissue and bone tumors, and to offer new perspectives on how to further promote and accelerate the translational process. It comprises high-quality original articles and timely reviews.

Presenilins and Nicastrin are Components of the -Secretease Complex Involved in APP and Notch Processing

An Herreman
Presenilins and Nicastrin are Components of the Secretease Complex Involved in APP and Notch Processing Book PDF

Author : An Herreman
Publisher : Leuven University Press
Page : 110 pages
File Size : 42,6 Mb
Release : 2003-12
Category : Medical
ISBN : 9058673391

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Presenilins and Nicastrin are Components of the -Secretease Complex Involved in APP and Notch Processing by An Herreman Pdf

"This is a Ph.D. dissertation. Dementia is a major cause of disability and mortality. The most frequent type of dementia is Alzheimer's disease, accounting for about 70% of all dementia cases. Worldwide, about 20 million people suffer from Alzheimer's disease. With the increasing number of elderly in the world, Alzheimer's disease represents more and more a major health problem with an enormous impact on individuals, families, the health care system, and the society. Therefore, it is imperative that we understand the etiologies, the risk factors and the pathogenic mechanisms involved in Alzheimer's disease in order to develop effective treatments that ameliorate or even prevent this illness."

Protein Phosphatase-1 Binding Motifs

Paulina Wakula
Protein Phosphatase 1 Binding Motifs Book PDF

Author : Paulina Wakula
Publisher : Leuven University Press
Page : 138 pages
File Size : 47,9 Mb
Release : 2006
Category : Science
ISBN : 9058675211

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Protein Phosphatase-1 Binding Motifs by Paulina Wakula Pdf

Mechanisms of Mitotic Chromosome Segregation

J. Richard McIntosh
Mechanisms of Mitotic Chromosome Segregation Book PDF

Author : J. Richard McIntosh
Publisher : MDPI
Page : 341 pages
File Size : 44,5 Mb
Release : 2018-03-23
Category : Electronic
ISBN : 9783038424024

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Mechanisms of Mitotic Chromosome Segregation by J. Richard McIntosh Pdf

This book is a printed edition of the Special Issue "Mechanisms of Mitotic Chromosome Segregation" that was published in Biology

The Protein-bound Solute P-cresol

Bert Bammens
The Protein bound Solute P cresol Book PDF

Author : Bert Bammens
Publisher : Leuven University Press
Page : 276 pages
File Size : 55,6 Mb
Release : 2005
Category : Cresol
ISBN : 9058674827

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The Protein-bound Solute P-cresol by Bert Bammens Pdf

NIPP1, an Interactor of Protein Phosphatase-1, Displays Endoribonuclease and Transcriptional Repression Activities

Qiming Jin
NIPP1 an Interactor of Protein Phosphatase 1 Displays Endoribonuclease and Transcriptional Repression Activities Book PDF

Author : Qiming Jin
Publisher : Leuven University Press
Page : 122 pages
File Size : 51,6 Mb
Release : 2004
Category : Phosphoprotein phosphatases
ISBN : 9058673804

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NIPP1, an Interactor of Protein Phosphatase-1, Displays Endoribonuclease and Transcriptional Repression Activities by Qiming Jin Pdf

"This is a Ph.D. dissertation. This thesis deals with the eukaryotic protein NIPP1 (Nuclear Inhibitor of Protein Phosphate-1), which was initially described by the host laboratory in 1992 and still is the major focus of its research efforts. The first part of the introduction describes our current insights into the structure and function of NIPP1, with the exception of aspects that directly deal with this doctoral project. For reasons of clarity, the data are presented in a logical manner, which implies that they are not necessarily presented according to their order of discovery. In the final sections of the introduction, a brief overview will be given of the state of the art of the `structure and function of ribonucleases' and `transcriptional repression mechanisms,' two topics that directly related to this research project. Contents include: Introduction, The Structure and Function of NIPP1, The Structure and Function of Ribonucleases, Transcriptional Repression in Eukaryotes, Aims and Strategies, Materials and Methods, Results and Discussions, Mapping of the RNA-binding and Endoribonuclease Domain of NIPP1, Screening for Proteins that Interact with the C-Terminal domain of NIPP1."