Nutrigenomics And Beyond

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Nutrigenomics and Beyond

Author : Institute of Medicine,Food and Nutrition Board
Publisher : National Academies Press
Page : 90 pages
File Size : 54,6 Mb
Release : 2007-06-28
Category : Science
ISBN : 9780309179874

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Nutrigenomics and Beyond by Institute of Medicine,Food and Nutrition Board Pdf

The integration of biology, genomics, and health has opened the possibility of applying genomics technology to nutrition. In 2001, scientists associated with the Human Genome Project announced the successful mapping of the reference sequence of the human genome. Since then, a body of information has emerged. Genomics and related areas of research have contributed greatly to efforts to understand the cellular and molecular mechanisms underlying diet-disease relationships. Integration and application of genetic and genomics technology into nutrition research is, therefore, needed to develop nutrition research programs that are aimed at the prevention and control of chronic disease through genomics-based nutritional interventions. Of interest is the integration of relevant computational methods into nutritional genomics research; the enhancement of tools applicable to systems biology; and the effective dissemination of genomics-derived information to scientists, policy makers, and the interested public. To address these issues, a workshop was held on June 1 and 2, 2006. The workshop included presentations that were structured around three focus sessions: human genetic variation, epigenetics, and systems biology. A fourth session presented discussions on the implications of nutrigenomics for the future of nutrition science research. Numerous themes emerged from the workshop presentations. First, nutrigenomics is a complex field because it addresses issues related to multigenetic traits that can be modified by a number of nutritional and other environmental factors. Such complexity presents a challenge to the field; and the ensuing research opportunities will require cooperative work among scientific disciplines and across government, academic, and industrial centers, as well as adequate funding, to be realized. Additionally, the ability to stretch the limits of conventional research methodologies afforded by new genetic and genomic applications at the level of the individual opens the door to a wealth of potential benefits to areas such as disease prevention and wellness, bearing in mind the necessity of ethical safeguards. This potential, however, must be wisely exploited to avoid the pitfalls of overpromising research results and prematurely setting unrealistic expectations for beneficial outcomes. Finally, careful and rigorous research must be employed to optimize outcomes and assure acceptance by the scientific community. In summary, nutrition science is uniquely poised to serve as the crossroads for many disciplines and, using genomics tools, can bring this knowledge together to better understand and address diet-related chronic diseases and molecular responses to dietary factors.

Nutrigenomics and Nutrigenetics in Functional Foods and Personalized Nutrition

Author : Lynnette R. Ferguson
Publisher : CRC Press
Page : 439 pages
File Size : 47,5 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9781439876817

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Nutrigenomics and Nutrigenetics in Functional Foods and Personalized Nutrition by Lynnette R. Ferguson Pdf

While functional foods have become a reasonably well-established concept, personalized nutrition is still treated with skepticism by many. The recognition that people would have different nutrient requirements, or perceive foods in different ways, raises several concerns-some real, some not so real. Nutrigenomics and Nutrigenetics in Functional Foo

Nutrigenomics

Author : Carsten Carlberg,Stine Marie Ulven,Ferdinand Molnár
Publisher : Springer
Page : 237 pages
File Size : 51,6 Mb
Release : 2016-06-11
Category : Science
ISBN : 9783319304151

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Nutrigenomics by Carsten Carlberg,Stine Marie Ulven,Ferdinand Molnár Pdf

The fascinating area of Nutrigenomics describes this daily communication between diet, food and nutrients, their metabolites and our genome. This book describes how nutrition shapes human evolution and demonstrates its consequences for our susceptibility to diseases, such as diabetes and atherosclerosis. Inappropriate diet can yield stress for our cells, tissues and organs and then it is often associated with low-grade chronic inflammation. Overnutrition paired with physical inactivity leads to overweight and obesity and results in increased burden for a body that originally was adapted for a life in the savannas of East Africa. Therefore, this textbook does not discuss a theoretical topic in science, but it talks about real life, and our life-long “chat” with diet. We are all food consumers, thus each of us is concerned by the topic of this book and should be aware of its mechanisms. The purpose of this book is to provide an overview on the principles of nutrigenomics and their relation to health or disease. We are not aiming to compete with more comprehensive textbooks on molecular nutrition, evolutionary biology, genomics, gene regulation or metabolic diseases, but rather will focus on the essentials and will combine, in a compact form, elements from different disciplines. In order to facilitate the latter, we favor a high figure-to-text ratio following the rule “a picture tells more than thousand words”. The content of this book is based on the lecture course “Nutrigenomics”, which is held since 2003 once per year by Prof. Carlberg at the University of Eastern Finland in Kuopio. The book is subdivided into three sections and twelve chapters. Following the "Introduction" there are sections on the "Molecular genetic basis" and the "Links to disease", which take a view on nutrigenomics from the perspective of molecular mechanisms or from the causes of metabolic diseases, respectively. Besides its value as a textbook, Nutrigenomics will be a usefull reference for individuals working in biomedicine.

Recent Advances in Nutrigenetics and Nutrigenomics

Author : C Bouchard,J. M. Ordovas
Publisher : Academic Press
Page : 521 pages
File Size : 44,5 Mb
Release : 2012-06-19
Category : Medical
ISBN : 9780123983978

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Recent Advances in Nutrigenetics and Nutrigenomics by C Bouchard,J. M. Ordovas Pdf

Recent Advances in Nutrigenetics and Nutrigenomics.

Nutrigenomics and the Future of Nutrition

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Food and Nutrition Board,Food Forum
Publisher : National Academies Press
Page : 155 pages
File Size : 55,5 Mb
Release : 2018-07-27
Category : Medical
ISBN : 9780309477673

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Nutrigenomics and the Future of Nutrition by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Food and Nutrition Board,Food Forum Pdf

On December 5, 2017, the National Academies of Sciences, Engineering, and Medicine hosted a public workshop titled Nutrigenomics and the Future of Nutrition in Washington, DC, to review current knowledge in the field of nutrigenomics as it relates to nutrition. Workshop participants explored the influence of genetic and epigenetic expression on nutritional status and the potential impact of personalized nutrition on health maintenance and chronic disease prevention. This publication summarizes the presentations and discussions from the workshop.

Nutrigenetics and Nutrigenomics

Author : Artemis P. Simopoulos,J. M. Ordovas
Publisher : Karger Medical and Scientific Publishers
Page : 337 pages
File Size : 41,6 Mb
Release : 2004-01-01
Category : Health & Fitness
ISBN : 9783805577823

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Nutrigenetics and Nutrigenomics by Artemis P. Simopoulos,J. M. Ordovas Pdf

For the first time, international scientists describe the advances in genetics and nutrition by combining methods of molecular biology with those of functional genetics, also known as systems biology. This book provides the latest data on genetic variation and dietary response, nutrients and gene expression, and the contribution molecular biology has given to systems biology. It also includes a comprehensive critique of genetic association studies in defining the risk of chronic diseases and concludes that molecular diagnostic tests will eventually affect every area of health care from individual risk prediction, early diagnosis of disease, and determination of optimal treatment regimens, to monitoring treatment effectiveness. The appendix contains an extensive glossary of the newly emerging terminology, as well as recommendations for genetic screening. This publication is an essential tool for the future work of all physicians, nutritionists, dietitians, geneticists, physiologists, molecular biologists, anthropologists, food technologists, policy makers, ethicists and educators.

Nutrigenomics and Nutraceuticals

Author : Yashwant V. Pathak,Ali M. Ardekani
Publisher : CRC Press
Page : 568 pages
File Size : 54,7 Mb
Release : 2017-09-29
Category : Technology & Engineering
ISBN : 9781498765121

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Nutrigenomics and Nutraceuticals by Yashwant V. Pathak,Ali M. Ardekani Pdf

Genomics and related areas of research have contributed greatly to the understanding of the cellular and molecular mechanisms underlying diet–disease relationships. In the past decade, the evidence has become stronger for a direct link between genome/epigenome damage and increased risk for adverse health outcomes. It is now exceedingly clear that micronutrients are critical as cofactors for many cellular functions, including DNA repair enzymes, methylation of CpG sequences, DNA oxidation, and/or uracil incorporation into DNA. Nutrigenomics and Nutraceuticals: Clinical Relevance and Disease Prevention brings new perspectives on disease prevention strategy based on the genomic knowledge and nutraceuticals of an individual and the diet he or she receives. This book discusses the integration and application of genetic and genomics technology into nutrition research and paves the way for the development of nutrition research programs that are aimed at the prevention and control of chronic disease through genomics-based nutritional interventions. In this book, the editors bring together a wide spectrum of nutritional scientists worldwide to contribute to the growing knowledge in the field of nutrigenomics and nutraceuticals.

Science, Society, and the Supermarket

Author : David Castle,Cheryl Cline,Abdallah S. Daar,Charoula Tsamis,Peter A. Singer
Publisher : John Wiley & Sons
Page : 192 pages
File Size : 42,7 Mb
Release : 2006-12-22
Category : Technology & Engineering
ISBN : 9780470055496

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Science, Society, and the Supermarket by David Castle,Cheryl Cline,Abdallah S. Daar,Charoula Tsamis,Peter A. Singer Pdf

The new science of nutrigenomics and its ethical and societal challenges Gene-diet interactions--which underlie relatively benign lactose intolerance to life-threatening conditions such as cardiovascular disease--have long been known. But until now, scientists lacked the tools to fully understand the underlying mechanisms that cause these conditions. In recent years, however, strides in human genomics and the nutritional sciences have allowed for the advancement of a new science--dubbed nutrigenomics. Although this science may lead to personalized nutrition and dietary recommendations that can mitigate, prevent, or cure sickness, current oversight mechanisms and regulations for emerging direct-to-public nutrigenomic tests are still in their infancy. Science, Society, and the Supermarket: The Opportunities and Challenges of Nutrigenomics discusses the many ethical, legal, and social challenges presented by nutrigenomics. Concerning itself with the basic uses of nutrigenomic research as well as its clinical and commercial aspects, this text sheds light on such issues as: * Opportunities and challenges for nutrigenomics * The science of nutrigenomics * The ethics of nutrigenomic tests and information both in a clinical setting and by private third parties * Alternatives for nutrigenomics service delivery * Nutrigenomics and the regulation of health claims for foods and drugs * Equity and access to nutrigenomics in industrialized and developing countries * Intellectual property issues By taking a proactive bioethical stance on the subject, Science, Society, and the Supermarket offers a thorough and timely analysis on both the benefits and risks of nutrigenomics. Along with a thought-provoking examination of the issues, this book provides ethical guidelines and recommendations for further study in policy and regulatory development.

Molecular Nutrition and Genomics

Author : Mark Lucock
Publisher : John Wiley & Sons
Page : 154 pages
File Size : 49,9 Mb
Release : 2007-07-16
Category : Medical
ISBN : 9780470129371

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Molecular Nutrition and Genomics by Mark Lucock Pdf

This fascinating book draws it subject matter from a range of relevant disciplines that extend from molecular nutrition, nutritional sciences, and nutrition dietetics through to genetics, genomics, and anthropology. It presents a vital portrait of the absolutely fundamental role that nutrition has played and continues to play in shaping who and what human beings are, as well as where they evolved from, and where they may be heading as a species. Molecular Nutrition: Nutrition and the Evolution of Humankind: Blends coverage of the molecular mechanisms that underpin nutrient-gene interactions with evolutionary theory Takes a molecular biological approach to problem solving, and moves nutrition away from its dietetic and anthropological origins to the front lines of genomic research Covers key concepts in molecular biology; the –omics revolution and bioinformatics; recent human evolution; molecular mechanisms of gene-nutrient interactions; the importance of nutrients and genomics in disease; the evolution of micronutrient metabolism, protein structure, and human disease; nutrients and the human lifecycle; contemporary dietary patterns; leading-edge laboratory tools in nutrigenomics and human evolutionary studies Written by an internationally recognised expert in the field, Molecular Nutrition: Nutrition and the Evolution of Humankind is an invaluable text and reference book for a wide range of teachers, students, and researchers.

Principles of Nutrigenetics and Nutrigenomics

Author : Raffaele De Caterina,J. Alfredo Martinez,Martin Kohlmeier
Publisher : Academic Press
Page : 586 pages
File Size : 49,7 Mb
Release : 2019-09-22
Category : Medical
ISBN : 9780128045879

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Principles of Nutrigenetics and Nutrigenomics by Raffaele De Caterina,J. Alfredo Martinez,Martin Kohlmeier Pdf

Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is the most comprehensive foundational text on the complex topics of nutrigenetics and nutrigenomics. Edited by three leaders in the field with contributions from the most well-cited researchers conducting groundbreaking research in the field, the book covers how the genetic makeup influences the response to foods and nutrients and how nutrients affect gene expression. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is broken into four parts providing a valuable overview of genetics, nutrigenetics, and nutrigenomics, and a conclusion that helps to translate research into practice. With an overview of the background, evidence, challenges, and opportunities in the field, readers will come away with a strong understanding of how this new science is the frontier of medical nutrition. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is a valuable reference for students and researchers studying nutrition, genetics, medicine, and related fields. Uniquely foundational, comprehensive, and systematic approach with full evidence-based coverage of established and emerging topics in nutrigenetics and nutrigenomics Includes a valuable guide to ethics for genetic testing for nutritional advice Chapters include definitions, methods, summaries, figures, and tables to help students, researchers, and faculty grasp key concepts Companion website includes slide decks, images, questions, and other teaching and learning aids designed to facilitate communication and comprehension of the content presented in the book

Nutritional Genomics

Author : Regina Brigelius-Flohé,Hans-Georg Joost
Publisher : John Wiley & Sons
Page : 470 pages
File Size : 45,5 Mb
Release : 2006-08-21
Category : Science
ISBN : 9783527607754

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Nutritional Genomics by Regina Brigelius-Flohé,Hans-Georg Joost Pdf

Nutritional genomics paves the way for novel applications in medicine and human nutrition, and this volume presents the latest data on how genetic variation is associated with dietary response and how nutrients influence gene expression. In so doing, it brings together the various disciplines involved in this field of research, making this essential reading for nutritionists, biochemists and molecular biologists.

Nutrigenomics: How Science Works

Author : Carsten Carlberg,Stine Marie Ulven,Ferdinand Molnár
Publisher : Springer Nature
Page : 195 pages
File Size : 54,5 Mb
Release : 2020-02-14
Category : Medical
ISBN : 9783030369484

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Nutrigenomics: How Science Works by Carsten Carlberg,Stine Marie Ulven,Ferdinand Molnár Pdf

The fascinating area of Nutrigenomics describes this daily communication between our diet and our genome. This book describes how nutrition shapes human evolution and demonstrates its consequences for our susceptibility to diseases, such as diabetes and atherosclerosis. Inappropriate diet can yield stress for our cells, tissues and organs and then it is often associated with low-grade chronic inflammation. Overnutrition paired with physical inactivity leads to overweight and obesity and results in increased burden for a body that originally was adapted for a life in the savannahs of East Africa. Therefore, this textbook does not discuss a theoretical topic in science, but it talks about real life and our life-long “chat” with diet. We are all food consumers, thus each of us is concerned by the topic of this book and should be aware of its mechanisms. The purpose of this book is to provide an overview on the principles of nutrigenomics and their relation to health or disease. The content of this book is based on the lecture course “Nutrigenomics”, which is held since 2003 once per year by Prof. Carlberg at the University of Eastern Finland in Kuopio. The book represents an updated but simplified version of our textbook “Nutrigenomics” (ISBN 978-3-319-30413-7). Besides its value as a textbook, “Nutrigenomics: how science works” will be a useful reference for individuals working in biomedicine

Using Nutrigenomics within Personalized Nutrition

Author : Anne Pemberton
Publisher : Singing Dragon
Page : 394 pages
File Size : 54,8 Mb
Release : 2022-07-21
Category : Health & Fitness
ISBN : 9780857013682

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Using Nutrigenomics within Personalized Nutrition by Anne Pemberton Pdf

This is the comprehensive guide to utilising nutrigenomics in clinical practice. A cutting-edge field, nutrigenomics examines the effects of foods on gene expression. From a comprehensive patient history and appropriate testing, practitioners can work with the patient to correct underlying biochemical imbalances that may predispose to a disease, using nutrigenomics as a guidance tool. The book covers everything a practitioner needs to know, from the difference between nutrigenomics and epigenetics to what to consider when incorporating nutrigenomics with functional medicine. The book is highly practical, guiding the reader through the realities of using genetic testing in clinical practice.

Nutrigenetics

Author : Martin Kohlmeier
Publisher : Academic Press
Page : 396 pages
File Size : 42,9 Mb
Release : 2012-12-31
Category : Technology & Engineering
ISBN : 9780123859013

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Nutrigenetics by Martin Kohlmeier Pdf

Nutrigenetics: Applying the Science of Personal Nutrition provides a fully referenced, readable guide to understanding the rationale and importance of nutrigenetic applications and explains why single nutrition recommendations will not fit everybody or even a majority of modern humans. This books explains how genetic variation shapes individual nutrition requirements and sensitivities, presents questions to ask about reported gene-nutrient interactions, and what needs to be done before putting nutrigenetic tests to practical use. This book blends key concepts from the fields of genetics, biochemistry, epidemiology, public health, and clinical medicine to give a rich perspective on the genetically diverse nutritional needs and sensitivities of individuals in health and disease. A steadily increasing number of people order genetic tests to find out what they should eat for better health, well being and performance, and an even greater number asks their healthcare providers about such tests. Most of the currently offered tests are not grounded in current knowledge, often absurdly so, but few professionals can explain why they are misguided. On the other hand, there are more evidence-supported genetic variants that can guide nutrition decisions, but again most healthcare providers know little about them, much less use them in their daily practice. There is a great need for a solidly evidence-based yet accessible book that explains the science of nutrigenetics and provides the tools to evaluate new nutrigenetic tests. Comprehensive coverage of the emerging science of nutritional genetics and its promise for individually tailored nutrition guidance Presents practical examples to enhance comprehension and spur additional research Offers a logical progression from what nutrigenetics is, to its possibilities in enhancing health

Nutrigenomics and Proteomics in Health and Disease

Author : Martin Kussmann,Patrick J. Stover
Publisher : John Wiley & Sons
Page : 350 pages
File Size : 54,8 Mb
Release : 2017-05-08
Category : Technology & Engineering
ISBN : 9781119098836

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Nutrigenomics and Proteomics in Health and Disease by Martin Kussmann,Patrick J. Stover Pdf

Now in a revised second edition, Nutrigenomics and Proteomics in Health and Disease brings together the very latest science based upon nutrigenomics and proteomics in food and health. Coverage includes many important nutraceuticals and their impact on gene interaction and health. Authored by an international team of multidisciplinary researchers, this book acquaints food and nutrition professionals with these new fields of nutrition research and conveys the state of the science to date. Thoroughly updated to reflect the most current developments in the field, the second edition includes six new chapters covering gut health and the personal microbiome; gut microbe-derived bioactive metabolites; proteomics and peptidomics in nutrition; gene selection for nutrigenomic studies; gene-nutrient network analysis, and nutrigenomics to nutritional systems biology. An additional five chapters have also been significantly remodelled. The new text includes a rethinking of in vitro and in vivo models with regard to their translatability into human phenotypes, and normative science methods and approaches have been complemented by more comprehensive systems biology-based investigations, deploying a multitude of omic platforms in an integrated fashion. Innovative tools and methods for statistical treatment and biological network analysis are also now included.