Organometallic Chemistry In Industry

Author : Thomas J. Colacot,Carin C.C. Johansson Seechurn
Publisher : John Wiley & Sons
Page : 336 pages
File Size : 52,5 Mb
Release : 2020-05-26
Category : Science
ISBN : 9783527345175

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Organometallic Chemistry in Industry by Thomas J. Colacot,Carin C.C. Johansson Seechurn Pdf

Showcases the important role of organometallic chemistry in industrial applications and includes practical examples and case studies This comprehensive book takes a practical approach to how organometallic chemistry is being used in industrial applications. It uniquely offers numerous, real-world examples and case studies that aid working R&D researchers as well as Ph.D. and postdoc students preparing to ace interviews in order to enter the workforce. Edited by two world-leading and established industrial chemists, the book covers flow chemistry (catalytic and non-catalytic organometallic chemistry), various cross-coupling reactions (C-C, C-N, and C-B) in classical batch chemistry, conjugate addition reactions, metathesis, and C-H arylation and achiral hydrogenation reactions. Beginning with an overview of the many industrial milestones within the field over the years, Organometallic Chemistry in Industry: A Practical Approach provides chapters covering: the design, development, and execution of a continuous flow enabled API manufacturing route; continuous manufacturing as an enabling technology for low temperature organometallic chemistry; the development of a nickel-catalyzed enantioselective Mizoroki-Heck coupling; and the development of iron-catalyzed Kumada cross-coupling for the large scale production of Aliskiren intermediates. The book also examines aspects of homogeneous hydrogenation from industrial research; the latest industrial uses of olefin metathesis; and more. -Includes rare industrial case studies difficult to find in current literature -Helps readers successfully carry out their own reactions -Covers topics like flow chemistry, cross-coupling reactions, and dehydrative decarbonylation -Features a foreword by Nobel Laureate R. H. Grubbs -A perfect resource for every R&D researcher in industry -Useful for PhD students and postdocs: excellent preparation for a job interview Organometallic Chemistry in Industry: A Practical Approach is an excellent resource for all chemists, including those working in the pharmaceutical industry and organometallics.

Author : Matthias Beller,Hans-Ulrich Blaser
Publisher : Springer
Page : 156 pages
File Size : 41,6 Mb
Release : 2012-08-31
Category : Science
ISBN : 9783642328336

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Organometallics as Catalysts in the Fine Chemical Industry by Matthias Beller,Hans-Ulrich Blaser Pdf

Johannes G. de Vries: Pd-catalyzed coupling reactions.- Gregory T. Whiteker and Christopher J. Cobley: Applications of Rhodium-Catalyzed Hydroformylation in the Pharmaceutical, Agrochemical and Fragrance Industries.- Philippe Dupau: Ruthenium-catalyzed Selective Hydrogenation for Flavor and Fragrance Applications.- Hans-Ulrich Blaser, Benoît Pugin and Felix Spindler: Asymmetric Hydrogenation.- Ioannis Houpis: Case Study: Sequential Pd-catalyzed Cross-Coupling Reactions; Challenges on Scale-up.- Adriano F. Indolese: Pilot Plant Scale Synthesis of an Aryl-Indole - Scale up of a Suzuki Coupling.- Per Ryberg: Development of a Mild and Robust Method for Palladium Catalysed Cyanation on Large Scale.- Cheng-yi Chen: Application of Ring Closing Metathesis Strategy to the Synthesis of Vaniprevir (MK-7009), a 20-Membered Macrocyclic HCV Protease Inhibitor.

Author : Anonim
Publisher : Academic Press
Page : 414 pages
File Size : 41,9 Mb
Release : 1996-02-12
Category : Technology & Engineering
ISBN : 0080580408

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Advances in Organometallic Chemistry by Anonim Pdf

This widely acclaimed serial contains authoritative reviews that address all aspects of organometallic chemistry, a field which has expanded enormously since the publication of Volume 1 in 1964. Almost all branchesof chemistry now interface with organometallic chemistry--the study of compounds containing carbon metal bonds. Organometallic compounds range from species which are so reactive that they only have a transient existence at ambient temperatures to species which are thermally very stable. Organometallics are used extensively in the synthesis of useful compounds on both large and small scales. Industrial processes involving plastics, polymers, electronic materials, and pharmaceuticals all depend on advancements in organometallic chemistry. In basic research, organometallics have contributed inter alia to: Metal cluster chemistry Surface chemistry The stabilization of highly reactive species by metal coordination Chiral synthesis The formulation of multiple bonds between carbon and the other elements and between the elements themselves

Author : Thomas J. Colacot,Vilvanathan Sivakumar
Publisher : Springer Nature
Page : 334 pages
File Size : 43,5 Mb
Release : 2020-04-01
Category : Science
ISBN : 9783030279615

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Organometallics in Process Chemistry by Thomas J. Colacot,Vilvanathan Sivakumar Pdf

This volume gives an overview of the applications of organometallic chemistry in process chemistry relevant to the current topics in synthetic chemistry. This volume starts with an introduction on the historical development of organometallics in process chemistry and is followed by chapters dealing with the last five years’ development in various organometallic reaction types such as the challenging cross coupling process, construction of 3.1.0 bicycles, pressure and transfer hydrogenations of historically challenging compounds such as esters, utilization of carbon dioxide for making organic compounds by flow process, drug synthesis and metal detection and scavenging in the finished APIs. A chapter by Colacot et.al., is also devoted to the process development and structural understanding of organometallic catalysts with particular emphasis to LnPd(0) catalysts. An academia – industry collaborated chapter on the use of water as a solvent for organometallic processes is included in this book.

Author : Anthony F. Hill,Mark J. Fink
Publisher : Academic Press
Page : 480 pages
File Size : 42,9 Mb
Release : 2011-08-09
Category : Science
ISBN : 0080922570

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Advances in Organometallic Chemistry by Anthony F. Hill,Mark J. Fink Pdf

Almost all branches of chemistry and material science now interface with organometallic chemistry--the study of compounds containing carbon-metal bonds. This widely acclaimed serial contains authoritative reviews that address all aspects of organometallic chemistry, a field that has expanded enormously since the publication of Volume 1 in 1964. * Fully updated and expanded to reflect recent advances * Illustrated with pertinenet examples from recent literature * Contributions from leading authorities and industry experts

Author : Ahmed F. Abdel-Magid
Publisher : Springer Science & Business Media
Page : 316 pages
File Size : 44,5 Mb
Release : 2004-06-15
Category : Science
ISBN : 3540016031

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Organometallics in Process Chemistry by Ahmed F. Abdel-Magid Pdf

The design of efficient syntheses of medicinal agents is one of the prime goals of the process chemist in the pharmaceutical industry. The expanding list of metal-mediated reactions has had a major impact on this endeavor over the last two decades. This volume will highlight some of the areas of organometallic chemistry that have played a particularly important role in development. The chapters are written by chemists who work in the process groups of major pharmaceutical companies and fine chemical manufacturers. Having demonstrated the power of organometallics in their processes the authors herein expand upon their experiences with examples from the literature as reported by process groups within the industry. The chapters are organized either by the application of a particular metal or reaction class. Removal of the residual metal(s) from the isolated active pharmaceutical ingredient (API) is key to the release of the material for human consumption, and hence, is reviewed here as well. This volume of Topics in Organometallic Chemistry is presented to offer a representative cross section of organometallic applications in the pharmaceutical industry as well as to give an appreciation for the creativity possible in process chemistry.

Author : Didier Astruc
Publisher : Springer Science & Business Media
Page : 598 pages
File Size : 52,7 Mb
Release : 2007-08-14
Category : Science
ISBN : 9783540461296

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Organometallic Chemistry and Catalysis by Didier Astruc Pdf

This volume covers both basic and advanced aspects of organometallic chemistry of all metals and catalysis. In order to present a comprehensive view of the subject, it provides broad coverage of organometallic chemistry itself. The catalysis section includes the challenging activation and fictionalization of the main classes of hydrocarbons and the industrially crucial heterogeneous catalysis. Summaries and exercises are provides at the end of each chapter, and the answers to these exercises can be found at the back of the book. Beginners in inorganic, organic and organometallic chemistry, as well as advanced scholars and chemists from academia and industry will find much value in this title.

Author : Thomas J. Colacot,Carin C.C. Johansson Seechurn
Publisher : John Wiley & Sons
Page : 336 pages
File Size : 45,6 Mb
Release : 2020-02-11
Category : Science
ISBN : 9783527819171

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Organometallic Chemistry in Industry by Thomas J. Colacot,Carin C.C. Johansson Seechurn Pdf

Showcases the important role of organometallic chemistry in industrial applications and includes practical examples and case studies This comprehensive book takes a practical approach to how organometallic chemistry is being used in industrial applications. It uniquely offers numerous, real-world examples and case studies that aid working R&D researchers as well as Ph.D. and postdoc students preparing to ace interviews in order to enter the workforce. Edited by two world-leading and established industrial chemists, the book covers flow chemistry (catalytic and non-catalytic organometallic chemistry), various cross-coupling reactions (C-C, C-N, and C-B) in classical batch chemistry, conjugate addition reactions, metathesis, and C-H arylation and achiral hydrogenation reactions. Beginning with an overview of the many industrial milestones within the field over the years, Organometallic Chemistry in Industry: A Practical Approach provides chapters covering: the design, development, and execution of a continuous flow enabled API manufacturing route; continuous manufacturing as an enabling technology for low temperature organometallic chemistry; the development of a nickel-catalyzed enantioselective Mizoroki-Heck coupling; and the development of iron-catalyzed Kumada cross-coupling for the large scale production of Aliskiren intermediates. The book also examines aspects of homogeneous hydrogenation from industrial research; the latest industrial uses of olefin metathesis; and more. -Includes rare industrial case studies difficult to find in current literature -Helps readers successfully carry out their own reactions -Covers topics like flow chemistry, cross-coupling reactions, and dehydrative decarbonylation -Features a foreword by Nobel Laureate R. H. Grubbs -A perfect resource for every R&D researcher in industry -Useful for PhD students and postdocs: excellent preparation for a job interview Organometallic Chemistry in Industry: A Practical Approach is an excellent resource for all chemists, including those working in the pharmaceutical industry and organometallics.

Author : Boy Cornils,Wolfgang A. Herrmann
Publisher : John Wiley & Sons
Page : 780 pages
File Size : 50,5 Mb
Release : 2006-03-06
Category : Science
ISBN : 9783527605460

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Aqueous-Phase Organometallic Catalysis by Boy Cornils,Wolfgang A. Herrmann Pdf

Now in its second completely revised and expanded edition. Written by the renowned editors B. Cornils and W. A. Herrmann, this book presents every important aspect of aqueous-phase organometallic catalysis, a method which saves time, waste and money. The large-scale application of this "green" technology in chemical industry clearly underlines its practical use outside of academia. New chapters (for example "Organic Chemistry in Water"), 20% more content and fully updated contributions from a plethora of international authors make this book a "must-have" for everyone working in this field. From the reviews of the first edition: "This overview will be extremely useful for everyone active in this field [...]" Angewandte Chemie "This book is an essential in any chemical research library and I strongly recommend it to all synthetic research and teaching chemists. [...]" The Alchemist "The editors are to be congratulated on assembling such a wide range of contributors who have described the industrial as well as the academic aspects of the subject." [...] Journal of Organometallic Chemistry

Author : P. J. Craig
Publisher : John Wiley & Sons
Page : 434 pages
File Size : 47,5 Mb
Release : 2003-09-12
Category : Science
ISBN : 9780470864883

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Organometallic Compounds in the Environment by P. J. Craig Pdf

A knowledge of the chemical structure and concentration of organometal compounds throughout the ecosystem is important in working out the pathways and mechanisms by which metals distribute themselves throughout the environment. Treating the topic as an integrated subject area, the Second Edition of Organometallic Compounds in the Environment covers all the recent developments in analytical techniques and reports all the new work that has been achieved since the first book. Covers the general importance and characteristics of organometallic species. Includes general developments in analytical techniques. Discusses several minority elements including antimony and selenium. The book addresses the subject in a single, manageable size and each chapter can be used either as a single review or sequentially within the topic area. A useful resource for all researchers and scientists in industry working with organometallic compounds, including, chemists, environmentalists and ecologists.

Author : Pierre H. Dixneuf,Jean-François Soulé
Publisher : Springer
Page : 301 pages
File Size : 53,6 Mb
Release : 2019-02-25
Category : Science
ISBN : 9783030109554

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Organometallics for Green Catalysis by Pierre H. Dixneuf,Jean-François Soulé Pdf

This volume presents the latest developments in the use of organometallic catalysis for the formation of bulk chemicals and the production of energy, via green processes including efficient utilization of waste feedstocks from industry. The chemistry of carbon dioxide relating to its hydrogenation into methanol –an eco-friendly energy storage strategy– and its uses as C1 synthon for the formation of important building-blocks for fine chemicals industry are covered. Catalytic hydrogenations of various functional groups and hydrogen transfer reactions including the use of first row metal catalysts are presented as well as the conversion of alcohols to carboxylates via hydrogen transfer with a zero-waste strategy using water. Transformation of renewable or bio-based raw materials is surveyed through alkene metathesis and C–O bond activations and functionalizations. A green aspect for selective formation of C-C, C-O and C-N bonds involves direct regioselective C–H bond activations and functionalizations. These transformations can now be promoted under mild reaction conditions due to the use photoredox catalyts. C–H bond oxidation using visible light leads mainly to the formation of C–O and C–N bonds, whereas cross-coupled C–C bonds can be formed through the radical additions on (hetero) arenes using photoredox assisted mechanism.

Author : Robert H. Crabtree
Publisher : John Wiley & Sons
Page : 600 pages
File Size : 46,7 Mb
Release : 2005-06-14
Category : Science
ISBN : 9780471718758

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The Organometallic Chemistry of the Transition Metals by Robert H. Crabtree Pdf

Fully updated and expanded to reflect recent advances, this Fourth Edition of the classic text provides students and professional chemists with an excellent introduction to the principles and general properties of organometallic compounds, as well as including practical information on reaction mechanisms and detailed descriptions of contemporary applications.

Author : Harold Zeiss
Publisher : Unknown
Page : 576 pages
File Size : 42,5 Mb
Release : 1960
Category : Organometallic chemistry
ISBN : UOM:39015012325380

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Organometallic Chemistry by Harold Zeiss Pdf

Author : Ionel Haiduc,Jerry J. Zuckerman
Publisher : Walter de Gruyter
Page : 517 pages
File Size : 46,6 Mb
Release : 2011-06-01
Category : Science
ISBN : 9783110847888

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Basic Organometallic Chemistry by Ionel Haiduc,Jerry J. Zuckerman Pdf

Author : Ionel Haiduc,Frank Thomas Edelmann
Publisher : John Wiley & Sons
Page : 484 pages
File Size : 53,9 Mb
Release : 2008-11-21
Category : Science
ISBN : 9783527613557

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Supramolecular Organometallic Chemistry by Ionel Haiduc,Frank Thomas Edelmann Pdf

Supramolecular chemistry has become not only a major field of chemistry, but is also a vivid interface between chemistry, biology, physics, and materials science. Although still a relatively young field, termini such as molecular recognition, host-guest chemistry, or self-assembly are now common knowledge even for chemistry students, and research has already been honored with a Nobel Prize. This first book on supramolecular organometallic chemistry combines two areas in chemistry that are experiencing the fastest developments. It provides a comprehensive review of various organometallic assemblies, arranged according to the types of intermolecular bonding. Details on the synthesis, structures, and properties of these compounds will be a valuable asset to the scientific community. The broad spectrum of assemblies containing main group element, transition metal, or f-element metal and a diverse range of ligands, held together by different bonding interactions make this a fascinating compilation. Illustrated extensively, this book is a very easily accessible, yet wide-ranging source of information.