Osteosarcopenia Bone Muscle And Fat Interactions

Author : Gustavo Duque
Publisher : Springer Nature
Page : 383 pages
File Size : 50,9 Mb
Release : 2019-11-06
Category : Science
ISBN : 9783030258900

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Osteosarcopenia: Bone, Muscle and Fat Interactions by Gustavo Duque Pdf

This edited work presents the most current evidence on osteosarcopenia from bench to bedside, which is expected to facilitate the understanding of this syndrome and to develop preventive and therapeutic strategies. With our aging population, chronic diseases such as osteoporosis and sarcopenia are becoming highly prevalent. Fortunately, our understanding of the bone and muscle interactions has increased in recent years. This has allowed to the coining of the term osteosarcopenia to describe a syndrome in which these two diseases overlap. This overlap between osteoporosis and sarcopenia has major negative effects not only on our older adults but also on health systems worldwide. Readers will find a highly translational approach that starts with a summary of recent discoveries on stem cells biology, muscle and bone interactions – including the role of local bone and muscle fat – followed by comprehensive reviews on myokines (i.e. myostatin), osteokines (i.e. osteocalcin) and adipokines (i.e. interleukins) as major players and determinants of bone and muscle loss with aging. In addition, the role of sex steroids (i.e. estrogens, androgens), and calciotropic hormones (i.e. parathyroid hormone, vitamin D) in the pathogenesis of this syndrome is also reviewed. Moreover, using practical diagnostic and therapeutic tips, this book summarizes the clinical characteristics of osteosarcopenic patients thus facilitating the diagnosis and treatment of this syndrome in clinical practice. Finally, the book presents the case for the Falls and Fractures Clinic as the optimal model of care for this syndrome, aimed to avoid fragmentation and optimize osteosarcopenia care, and simultaneously prevent falls and fractures in older persons. This book offers relevant information on the mechanisms of osteosarcopenia, and a practical guide on how to identify and treat this geriatric syndrome and its adverse outcomes, which are dramatically affecting our aging population. The work is written by leaders in the field and is especially suited not only to any researcher in the musculoskeletal arena but also to medical specialists and allied health professionals involved in the care of older persons.

Author : Gustavo Duque,Bruce R. Troen
Publisher : Elsevier
Page : 350 pages
File Size : 42,9 Mb
Release : 2022-03-04
Category : Medical
ISBN : 9780128204207

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Osteosarcopenia by Gustavo Duque,Bruce R. Troen Pdf

Falls, fractures, frailty, osteoporosis and sarcopenia are highly prevalent in older persons. While the concept of osteosarcopenia is new, it is a rapidly evolving and cross-disciplinary problem. Prevention and treatment are challenging and a combined therapeutic approach is needed. Osteosarcopenia provides evidence-based information on how to prevent and treat these conditions at multiple settings, including multiple illustrations, care pathways and tips to easily understand the pathophysiology, diagnostic methods and therapeutic approach to these conditions. This work evaluates the potential for a link between osteoporosis, sarcopenia and obesity. Presents diagnostic and therapeutic tips that facilitate the design and implementation of new care pathways, impacting the wellbeing of our older population Provides cross-disciplinary understanding by experts from the bone/osteoporosis field and the muscle/sarcopenia field Covers muscle and bone biology, mesenchymal stem cells, age-related changes and cross-talk between muscle, fat and bone, falls and fracture risk, glucose metabolism, diagnosis, imaging, and genetics of osteosarcopenia

Author : Elaine Dennison
Publisher : Springer Nature
Page : 229 pages
File Size : 44,8 Mb
Release : 2021-08-16
Category : Medical
ISBN : 9783030781286

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Osteoporosis Treatment by Elaine Dennison Pdf

This book provides a practical overview of osteoporosis for the wide spectrum of clinicians that might encounter the osteoporotic patient. Concise and well-structured chapters examine the public health importance of the condition, the current treatment gap, how to identify individuals who would benefit from treatment, bone turnover and how this can be modified by osteoporosis therapies, adjuvant lifestyle modification, the calcium and vitamin D story, antiresorptive therapies, anabolic therapies, emerging therapies, adherence and compliance with therapy and the perception of fracture risk. Osteoporosis Treatment: A Clinical Overview meets the need for a book that improves awareness of this major public health problem and possible therapeutic approaches. Primary care physicians, endocrinologists, rheumatologists, orthopaedic surgeons and those providing specialist care for the elderly will all benefit from this highly accessible and informative guide to treating osteoporosis.

Author : Connie M. Weaver,Heike Bischoff-Ferrari,Robin M. Daly,Man-Sau Wong
Publisher : Springer
Page : 275 pages
File Size : 40,8 Mb
Release : 2018-10-24
Category : Medical
ISBN : 9783319984643

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Nutritional Influences on Bone Health by Connie M. Weaver,Heike Bischoff-Ferrari,Robin M. Daly,Man-Sau Wong Pdf

This book comprehensively covers the topics and discussions covered at the 10th International Symposium on Nutritional Aspects of Osteoporosis. It is the only international meeting that exclusively covers the role of nutrition on musculoskeletal health and function. Current thinking on the role of nutrition on bone and muscle development and health, and as a means of preventing osteoporosis, falls and fractures is covered. The latest evidence on the potential roles that protein, potassium, B vitamins, vitamin D, omega-3 fatty acids, and flavonoids in the context of bone and muscle health are also discussed. Nutritional Influences on Bone Health reviews the role of nutrition in bone health and its potential role in preventing osteoporosis and sarcopenia in ageing populations, providing a valuable and practically applicable resource for practising and trainee health and medical professionals.

Author : Reiner Bartl
Publisher : Springer Nature
Page : 237 pages
File Size : 40,8 Mb
Release : 2023-03-03
Category : Medical
ISBN : 9783031146527

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Osteoporosis in Clinical Practice by Reiner Bartl Pdf

This book is a quick-reference guide to osteoporosis that equips the reader with easy-to-follow guidelines for lifelong maintenance of skeletal structure and function, with an emphasis on the diagnosis, therapy and prevention of osteoporosis. Organized into 20 chapters it provides a concise, yet complete evidence-based overview of osteoporosis prevention and management “from paediatrics to geriatrics”. This practical guide is aimed at raising awareness and educate physicians across disciplines about this preventable, treatable and now even curable disease and emphasizing how every doctor can contribute to stop the “osteoporosis treatment gap” recognized over the last ten years. Covering bone biology, pathophysiology, secondary and drug-induced osteoporosis, as well as risk factors, diagnostic measurements, treatment and monitoring strategies, new drugs, management of osteoporotic fractures, and much more, this book is a must-have for all those involved in the prevention and care of this global threat.

Author : Alexander Mauro
Publisher : Raven Press (ID)
Page : 582 pages
File Size : 53,7 Mb
Release : 1979
Category : Medical
ISBN : UOM:39015015064226

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Muscle Regeneration by Alexander Mauro Pdf

Author : Alfonso J. Cruz-Jentoft,John E. Morley
Publisher : John Wiley & Sons
Page : 478 pages
File Size : 52,5 Mb
Release : 2021-10-18
Category : Medical
ISBN : 9781119597872

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Sarcopenia by Alfonso J. Cruz-Jentoft,John E. Morley Pdf

SARCOPENIA An in-depth examination of sarcopenia’s underexplored yet widespread impact within the field of gerontology Sarcopenia is common in older men and women, and yet awareness of its clinical relevance is still relatively low. Only formally included in the International Classification of Diseases in 2016, the condition may impact societies with serious health-related and financial consequences unless consistent, effective methods of identification and management are adopted. This second edition of Sarcopenia provides geriatricians and other healthcare professionals with a revised and expanded examination of this understudied and underdiagnosed condition. Edited by two leading authorities on the subject, it covers the epidemiology and diagnosis of sarcopenia, as well as treatment options and possible prevention strategies. Eight newly written chapters build upon existing knowledge with fresh data on topics including sarcopenia’s biomarkers and its impact on the healthcare economy. This important text: Defines sarcopenia and explains its clinical relevance Covers all recent scientific evidence Outlines treatment options Considers prevention strategies Discusses sarcopenia as a public health priority Features eight new chapters covering topics such as sarcopenia’s clinical management, its biomarkers, and its financial impact Containing vital information for clinicians and other professionals working in geriatric care, nursing homes, nutrition, cancer, endocrinology, surgery, sports medicine and many other specialties, Sarcopenia, second edition, is a groundbreaking and essential new resource.

Author : Paolo Falaschi
Publisher : Springer Nature
Page : 355 pages
File Size : 52,9 Mb
Release : 2021
Category : Anesthesiology
ISBN : 9783030481261

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Orthogeriatrics by Paolo Falaschi Pdf

This new open access edition supported by the Fragility Fracture Network aims at giving the widest possible dissemination on fragility fracture (especially hip fracture) management and notably in countries where this expertise is sorely needed. It has been extensively revised and updated by the experts of this network to provide a unique and reliable content in one single volume. Throughout the book, attention is given to the difficult question of how to provide best practice in countries where the discipline of geriatric medicine is not well established and resources for secondary prevention are scarce. The revised and updated chapters on the epidemiology of hip fractures, osteoporosis, sarcopenia, surgery, anaesthesia, medical management of frailty, peri-operative complications, rehabilitation and nursing are supplemented by six new chapters. These include an overview of the multidisciplinary approach to fragility fractures and new contributions on pre-hospital care, treatment in the emergency room, falls prevention, nutrition and systems for audit. The reader will have an exhaustive overview and will gain essential, practical knowledge on how best to manage fractures in elderly patients and how to develop clinical systems that do so reliably.

Author : Paul Hough,Brad J. Schoenfeld
Publisher : Routledge
Page : 364 pages
File Size : 52,8 Mb
Release : 2021-11-22
Category : Sports & Recreation
ISBN : 9781000450408

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Advanced Personal Training by Paul Hough,Brad J. Schoenfeld Pdf

Effective fitness instruction and training programme design require an exercise specialist trainer to combine professional experience with strategies underpinned by scientific evidence. This book allows readers to develop their understanding of the scientific rationale behind important components of personal training, such as monitoring fitness and training programme design. Each chapter synthesizes the findings of cutting-edge scientific research to identify optimum training methods and dispel some myths that are prevalent in the fitness industry. The chapters within this new edition have been written by internationally renowned experts from several disciplines, including strength and conditioning, physiology, psychology, and nutrition. Contributions have also been made from esteemed academics who have conducted some of the scientific studies discussed within the book. The authors have interpreted and summarised the scientific evidence and produced evidence-based recommendations, allowing readers to explore the latest concepts and research findings and apply them in practice. The book includes several new chapters, such as evidenced based practice (EBP), and designing training programmes female clients. This second edition remains the essential text for fitness instructors, personal trainers and sport and exercise students. The book provides an invaluable resource for fitness courses, exercise science degree programmes and continued professional development for exercise professionals.

Author : Wolfgang Kemmler,Michael Fröhlich,Heinz Kleinöder
Publisher : Frontiers Media SA
Page : 160 pages
File Size : 49,7 Mb
Release : 2020-07-08
Category : Electronic
ISBN : 9782889638376

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Whole-body Electromyostimulation: A Training Technology to Improve Health and Performance in Humans? by Wolfgang Kemmler,Michael Fröhlich,Heinz Kleinöder Pdf

Author : WHO Scientific Group on Prevention and Management of Osteoporosis,World Health Organization
Publisher : World Health Organization
Page : 206 pages
File Size : 48,5 Mb
Release : 2003-12-31
Category : Medical
ISBN : 9789241209212

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Prevention and Management of Osteoporosis by WHO Scientific Group on Prevention and Management of Osteoporosis,World Health Organization Pdf

Bone is hard tissue that is in a constant state of flux being built up by bone-forming cells called osteoblasts while also being broken down or resorbed by cells known as osteoclasts. During childhood and adolescence bone formation is dominant; bone length and girth increase with age ending at early adulthood when peak bone mass is attained. Males generally exhibit a longer growth period resulting in bones of greater size and overall strength. In males after the age of 20 bone resorbtion becomes predominant and bone mineral content declines about 4% per decade. Females tend to maintain peak mineral content until menopause at which time it declines about 15% per decade. Osteoporosis is a disease characterized by low bone mass and structural deterioration of bone tissue leading to bone fragility and an increased susceptibility to fractures especially of the hip spine and wrist. Osteoporosis occurs primarily as a result of normal ageing but can arise as a result of impaired development of peak bone mass (e.g. due to delayed puberty or undernutrition) or excessive bone loss during adulthood (e.g. due to estrogen deficiency in women undernutrition or corticosteriod use). Osteoporosis-induced fractures cause a great burden to society. Hip fractures are the most serious as they nearly always result in hospitalization are fatal about 20% of the time and produce permanent disability about half the time. Fracture rates increase rapidly with age and the lifetime risk of fracture in 50 year-old women is about 40% similar to that for coronary heart disease. In 1990 there were 1.7 million hip fractures alone worldwide; with changes in population demographics this figure is expected to rise to 6 million by 2050. To help describe the nature and consequences of osteoporosis as well as strategies for its prevention and management a WHO Scientific Group meeting of international experts was held in Geneva which resulted in this technical report. This monograph describes in detail normal bone development and the causes and risk factors for developing osteoporosis. The burden of osteoporosis is characterized in terms of mortality morbidity and economic costs. Methods for its prevention and treatment are discussed in detail for both pharmacological and non-pharmacological approaches. For each approach the strength of the scientific evidence is listed. The report also provides cost-analysis information for potential interventions and discusses important aspects of developing national policies to deal with osteoporosis. Recommendations are made to the general population care providers health administrators and researchers. Lastly national organizations and support groups are listed by country.

Author : Anonim
Publisher : John Wiley & Sons
Page : 1136 pages
File Size : 52,5 Mb
Release : 2018-09-28
Category : Science
ISBN : 9781119266587

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Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism by Anonim Pdf

The authoritative reference to bone diseases and disorders of mineral metabolism, revised and updated Now in its ninth edition, The Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism offers an updated and comprehensive guide to bone and mineral health. Since it was first published 30 years ago, the Primer has become the leading reference on the topic. With contributions from noted experts, the text explores basic biological factors of healthy development and disease states and makes the information accessible for clinical interventions. The ninth edition provides concise coverage of the widest possible spectrum of metabolic bone diseases and disorders of mineral metabolism. The new edition of this invaluable reference expands coverage and includes the most recent developments in the field that help to strengthen its usefulness and ensure that the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism maintains its place as the pre-eminent reference on bone and mineral health. This vital resource: Provides the most accurate, up-to-date evidence-based information on basic and clinical bone science Includes more than 10 new chapters and contributions from 300 authors from wide-ranging international research centers Captures the very cutting edge of research covering mineral homeostasis, osteoporosis and other metabolic bone diseases, skeletal measurement technologies, and genetics Presents a new companion website with useful supplementary materials at www.asbmrprimer.com Written for advanced students, clinicians, and researchers working in the field of bone health and disease, Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism is the definitive, one-stop reference for anyone working in the field of bone health and disease.

Author : Alberto Ferlin,Silvia Migliaccio
Publisher : Springer Nature
Page : 221 pages
File Size : 41,8 Mb
Release : 2020-09-07
Category : Medical
ISBN : 9783319963761

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Male Osteoporosis by Alberto Ferlin,Silvia Migliaccio Pdf

This book represents a comprehensive, clinically oriented text covering all aspects of male osteoporosis, from the basic concepts of bone physiology and regulation of bone remodeling in men, the causes and pathophysiological mechanisms responsible for the most frequent causes of osteoporosis, to diagnostic and screening protocols, as well as prevention and treatment approaches. It offers a broad overview of male osteoporosis by specialists involved in research and clinical practice and discusses the practical issues encountered. Filling a gap in the literature, this volume is a valuable resource for general practitioners, clinical endocrinologists, geriatricians and experts in osteoporosis.

Author : Jack Feehan,Nicholas Tripodi,Vasso Apostolopoulos
Publisher : Academic Press
Page : 482 pages
File Size : 41,7 Mb
Release : 2022-04-30
Category : Science
ISBN : 9780323885768

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Exercise to Prevent and Manage Chronic Disease Across the Lifespan by Jack Feehan,Nicholas Tripodi,Vasso Apostolopoulos Pdf

Exercise to Prevent and Manage Chronic Disease Across the Lifespan provides evidence-based insights into the clinical utility of exercise in the management of disease across a broad range of specialties and diseases. The book offers research informed strategies for the integration of exercise into standard practice in fields such as neurology, endocrinology, psychiatry and oncology, as well as decision-making pathways and clinical scenarios to advance patient care. The book is divided by specialty and includes clinical scenarios to allow for the integration of information within practice. The book's synthesized research evidence allows practitioners to safely and effectively begin to capitalize on the benefits of exercise in their patients. Provides broad insights into the evidence-based underpinnings of the use of exercise in a range of common diseases Coverage includes the immune system, musculoskeletal disease, oncology, endocrinology, cardiology, respiratory diseases, and more Includes a glossary, bibliography and summary figures for quick reference of information

Author : Yasser El Miedany
Publisher : Springer Nature
Page : 903 pages
File Size : 48,8 Mb
Release : 2022-01-03
Category : Medical
ISBN : 9783030879501

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New Horizons in Osteoporosis Management by Yasser El Miedany Pdf

This book provides a review of the most recent data on osteoporosis and bone health, presenting a vision of diagnosis and management for the year 2021 and beyond. It covers all pertinent aspects of bone health including diagnosis, fracture prevention, optimized practice, impaired orthostasis, and falls. The book examines recent developments in therapeutics, including goal-directed therapy, individualizing therapy, sequential and combined therapies, pharmaceuticals, and anabolic vs. antiresorptive therapy. In addition, it provides an in-depth overview of osteoporosis and bone health in complex patients, covering Duchene dystrophy, renal failure, periodontal diseases, and steroid-induced osteoporosis as well as considerations for pediatric populations and men. New Horizons in Osteoporosis Management is an essential resource for physicians and related professionals, residents, fellows, graduate students and nurses in rheumatology, endocrinology, radiology, pediatrics, primary care, and internal medicine.