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An explosion of advances in the area of tactile perception and pain led to the development of this comprehensive, state-of-the-art text on basic research and clinical practice. Equal parts psychology and neuroscience, Pain and Touch covers peripheral cutaneous tactile information processing, sensory mapping, tactile exploratory behavior, neurophysiology of nociception and nociceptors in pain research, clinical scaling methods for psychophysics of pain, and paincontrol, pathology, and therapeutics.
An expert explores the biological and emotional nature of pain: why it hurts and why some pain is good and some pain is bad. If you touch something hot, it hurts. You snatch your hand away from the hot thing immediately. Obviously. But what is really happening, biologically—and emotionally? In Understanding Pain, Fernando Cervero explores the mechanisms and the meaning of pain. When you touch something hot, your brain triggers a reflex action that causes you to withdraw your hand, protecting you from injury. That kind of pain, Cervero explains, is actually good for us; it acts as an alarm that warns us of danger and keeps us away from harm. But, Cervero tells us, not all pain is good for you. There is another kind of pain that is more like a curse: chronic pain that is not related to injury. This is the kind of pain that fills pain clinics and makes life miserable. Cervero describes current research into the mysteries of chronic pain and efforts to develop more effective treatments. Cervero reminds us that pain is the most common reason for people to seek medical attention, but that it remains a biological enigma. It is protective, but not always. Its effects are not only sensory but also emotional. There is no way to measure it objectively, no test that comes back positive for pain; the only way a medical professional can gauge pain is by listening to the patient's description of it. The idea of pain as a test of character or a punishment to be borne is changing; prevention and treatment of pain are increasingly important to researchers, clinicians, and patients. Cervero's account brings us closer to understanding the meaning of pain.
Affective Touch and the Neurophysiology of CT Afferents by Håkan Olausson,Johan Wessberg,India Morrison,Francis McGlone Pdf
CT afferents are receptors in mammalian hairy skin that fire action potentials when the skin is touched lightly which makes them particularly important in affective touch. Traditionally neuroscientific research has focused on more discriminative and haptic properties of touch that are mediated by large myelinated afferents and the coding properties and functional organization of unmyelinated CT afferents have been studied much less. The proposed volume will draw together existing knowledge in this nascent field. Separate sections will address (1) how we can measure affective touch, (2) CT structure and physiology, (3) CT processing, (4) the contribution of CTs to sexual behavior, (5) clinical relevance, (6) commercial relevance, and (7) future research considerations.
A book that fundamentally changes how neuroscientists and psychologists categorize sensations and understand the origins and significance of human feelings How Do You Feel? brings together startling evidence from neuroscience, psychology, and psychiatry to present revolutionary new insights into how our brains enable us to experience the range of sensations and mental states known as feelings. Drawing on his own cutting-edge research, neurobiologist Bud Craig has identified an area deep inside the mammalian brain—the insular cortex—as the place where interoception, or the processing of bodily stimuli, generates feelings. He shows how this crucial pathway for interoceptive awareness gives rise in humans to the feeling of being alive, vivid perceptual feelings, and a subjective image of the sentient self across time. Craig explains how feelings represent activity patterns in our brains that signify emotions, intentions, and thoughts, and how integration of these patterns is driven by the unique energy needs of the hominid brain. He describes the essential role of feelings and the insular cortex in such diverse realms as music, fluid intelligence, and bivalent emotions, and relates these ideas to the philosophy of William James and even to feelings in dogs. How Do You Feel? is also a compelling insider's account of scientific discovery, one that takes readers behind the scenes as the astonishing answer to this neurological puzzle is pursued and pieced together from seemingly unrelated fields of scientific inquiry. This book will fundamentally alter the way that neuroscientists and psychologists categorize sensations and understand the origins and significance of human feelings.
A Little Book of Self Care: Trigger Points by Amanda Oswald Pdf
New science confirms that trigger-point massage is one of the most effective ways to relieve pain. Trigger Points gives you 40 simple, step-by-step exercises you can safely use at home to target pain - from long-term, debilitating backache or repetitive strain injury to migraines or acute, post-injury pain. Author and leading therapist Amanda Oswald specialises in working with chronic pain conditions. In this book, she explains how trigger points - small, tender knots of connective tissue - can cause symptoms, either around the trigger point itself or referred to elsewhere in the body. Pressure and massage can release these knots and bring immediate, long-lasting relief. Identify your pain patterns, locate the trigger points responsible using detailed body maps, then treat the trigger points accurately and safely. Each exercise shows you how to position your body, different ways to apply pressure, how long to sustain it, and how often to repeat the process. With Trigger Points, you can take control of chronic or recurring pain yourself to achieve life-changing results.
Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed, direct-line communication system from the skin to the brain. Itch: Mechanisms and Treatment presents a timely update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis, neuropathic itch, cutaneous t-cells lymphomas, and systemic diseases such as kidney and liver disease and cancer. Composed of contributions from distinguished researchers around the world, the book explores topics such as: Neuropathic itch Peripheral neuronal mechanism of itch The role of PAR-2 in neuroimmune communication and itch Mrgprs as itch receptors The role of interleukin-31 and oncostatin M in itch and neuroimmune communication Spinal coding of itch and pain Spinal microcircuits and the regulation of itch Examining new findings on cellular and molecular mechanisms, the book is a compendium of the most current research on itch, its prevalence in society, and the problems associated with treatment.
Challenging our understanding of what it means to be human, Joel Salinas, a Harvard-trained researcher and neurologist at Massachusetts General, shares his experiences with mirror-touch synesthesia, a rare and only recently identified neurological trait that causes him to feel the emotional and physical experiences of other people. Performing a spinal tap, he feels the needle slowly enter his lower back. If a disoriented patient flies into a confused rage, Salinas slips into a similarly agitated physical state, and when a patient dies, he experiences an involuntary ruin—his body starts to feel vacant and lifeless, like a limp balloon. Susceptible to the pain and discomfort of his patients, most of whom suffer from a host of disorders and extreme injuries, Salinas uses his trait to treat their symptoms, almost as if they were his own. At the same time, in his personal life, his mirror touch blurs the boundaries between himself and those close to him until he ends up inextricably entangled, no longer able to differentiate where he ends and someone else begins. Salinas refers to his condition as a kind of compulsory mindfulness, a heightened empathic ability that offers him invaluable clues about how to see and live the world through other people’s perspectives. This heightened sense of awareness is at the center of Mirror Touch. Through his experiences, both in his neurological practice and his personal life, Salinas offers readers insights about mirror-touch synesthesia and how the brain, in its endless wonder, can sometimes perform in a nearly superhuman, extrasensory way. In the process, Salinas reveals the full power and potential of his trait, as well as its thorny complications and often debilitating limitations. Beautifully written with intelligence and compassion and anchored by the latest developments in neurology, psychology, and psychiatry, Mirror Touch is an enthralling and wholly original investigation into the unexplored corners of the brain, where the foundation of human experience and relationships take root—everything it means to think, to feel, and to be.
Translational Pain Research by Lawrence Kruger,Alan R Light Pdf
One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practicality of clinical trials, Translational Pain Research: From Mouse to Man effectively bridges the gap between basic research and patient care by humanely examining rodent models for pain associated with bone cancer, osteoarthritis, fibromyalgia, and cardiac episodes. Distinguished Team of International Contributors In addition to addressing the groundbreaking technical advances in tract tracing, endocannabinoids, cannabis, gene therapy, siRNA gene studies, and the role of glia, cytokines, P2X receptors and ATP, this book also presents cutting-edge information on: Nociceptor sensitization Muscle nociceptors and metabolite detection Visceral afferents in disease Innovative rodent model for bone cancer pain Highly specific receptor cloning Modular molecular mechanisms relevant to painful neuropathies This sharply focused work also discusses unexpected discoveries derived from brain-imaging studies related to thalamic pain. Translational Pain Research covers the progress made toward bringing laboratory science (much of it at the molecular level) to our understanding of pain phenomena in humans, with the ultimate goal of reducing the suffering that often accompanies pain and its indirect consequences.
Trigger Point Therapy for Myofascial Pain by Donna Finando,Steven Finando Pdf
A clinical reference manual for the evaluation and treatment of muscle pain • Contains detailed illustrations of pain patterns and trigger-point locations • 15,000 copies sold in first hardcover edition Myofascial pain syndromes are among the fastest growing problems that physicians, osteopaths, acupuncturists, and physical, occupational, and massage therapists encounter in their patients. In Trigger Point Therapy for Myofascial Pain Donna and Steven Finando have organized vast amounts of information on treating myofascial pain into an accessible "user's manual" for healthcare practitioners. They examine a wide range of pain patterns and present evaluation and palpation techniques for reducing trigger points--and thereby alleviating pain--in the most clinically significant musculature of the body. This comprehensive yet easy-to-use reference guide to treatment of muscle pain begins with chapters on the concept of Qi and its relationship to myology, specific trigger point location and activation, and palpatory skill-building techniques. Subsequent sections provide detailed information on each muscle to teach clinicians to locate quickly and accurately individual points of pain and compensation. A visual index allows easy identification of the muscles that may be involved. Trigger Point Therapy for Myofascial Pain provides necessary and invaluable information for sufferers and any professional involved with myofascial disorders.
Proceedings of the 11th World Congress on Pain by Herta Flor,Eija Kalso,Jonathan O. Dostrovsky Pdf
11th World Congress on Pain was held August 21-26, 2005 at the Sydney Convention and Exhibition Centre, Darling Harbour, Sydney, Australia. Contents: List of contributing authors. Preface. Acknowledgements Part I IASP, the 11th World Congress on Pain, and Perspectives on Pain Part II Molecular and cellular aspects of pain Part III Nociceptive pathways and central processing Part IV Imaging pain Part V Opioids : Mechanisms and therapy Part VI Psychological and psychosocial factors, gender issues and epidemiology of pain Part VII Specific clinical syndromes and symptoms Part VIII Pain assessment and outcome measurement Part IX Psychological interventions, occupational therapy and physical approaches.
Institute of Medicine,Committee on Pain, Disability, and Chronic Illness Behavior
Author : Institute of Medicine,Committee on Pain, Disability, and Chronic Illness Behavior Publisher : National Academies Press Page : 318 pages File Size : 53,7 Mb Release : 1987-01-01 Category : Medical ISBN : 9780309037372
Pain and Disability by Institute of Medicine,Committee on Pain, Disability, and Chronic Illness Behavior Pdf
Painâ€"it is the most common complaint presented to physicians. Yet pain is subjectiveâ€"it cannot be measured directly and is difficult to validate. Evaluating claims based on pain poses major problems for the Social Security Administration (SSA) and other disability insurers. This volume covers the epidemiology and physiology of pain; psychosocial contributions to pain and illness behavior; promising ways of assessing and measuring chronic pain and dysfunction; clinical aspects of prevention, diagnosis, treatment, and rehabilitation; and how the SSA's benefit structure and administrative procedures may affect pain complaints.
Perioperative Pain Management for Orthopedic and Spine Surgery by John Reach,James J. Yue,Deepak Narayan Pdf
All physicians are involved in the management of pain at some level or the other, but of the various specialties and health professions, orthopedic surgeons are at the frontline of delivering perioperative pain care for a wide variety of problems that range from skeletal trauma, joint replacement procedures, bone tumors and spinal conditions. Perioperative Pain Management for Orthopedic and Spine Surgery offers a concise yet comprehensive overview of the surgical spine pain management field to help practitioners effectively plan and enhance perioperative pain control. Chapters provide guidance on solving common dilemmas facing surgeons who are managing patients with pain related problems and clinical decision-making, and explore essential topics required for the trainee and practitioner to quickly assess the patient with pain, to diagnose pain and painful conditions, determine the feasibility and safety of surgical procedure needed, and arrange for advanced pain management consults and care if needed. This text also explores the latest evolving techniques and appropriate utilization of modern equipment and technology to safely provide care. Highly accessible and written by experts in the field, Perioperative Pain Management for Orthopedic and Spine Surgery is an ideal resource for practicing orthopedic and spine surgeons, anesthesiologists, critical care personnel, residents, medical students.
Pain, Touch, and Decision Making by Lina Koppel Pdf
Stimulation of sensory nerves can give rise to powerful affective experiences. Noxious stimuli can give rise to pain, an unpleasant experience which, in turn, causes suffering and constitutes a major societal burden. Touch, on the other hand, can feel pleasant and plays an important role in social relationships and well-being. Slow, gentle stroking of the skin in particular has been shown to activate C-tactile (CT) afferents, which are thought to signal affective and socially relevant aspects of touch. However, little is known about how pain and affective touch influence everyday decision making. In Paper I, we investigated the effect of acute physical pain on risk taking and intertemporal choice. Participants (n = 109) performed a series of economic decision-making tasks, once while experiencing acute thermal pain and once in a no-pain control condition. Results indicated that pain increased risk taking for monetary gains but not for equivalent losses, and increased impatience. In Paper II, we investigated the effect of affective touch on betrayal aversion, altruism, and risk taking. Participants (n = 120) performed a series of economic decision-making tasks, once while being stroked on the forearm at CT-optimal speed using a soft painter’s brush and once in a no-touch control condition. Results indicated no effect of affective touch on any of the outcome measures. In Paper III, we investigated how the ability to affect an upcoming painful event via voluntary action influences cortical processing of ongoing somatosensory stimulation. fMRI data was collected from 30 participants while they performed a task that involved pressing a response button to reduce the duration of upcoming thermal stimuli. Whole-brain analyses revealed no significant task-related effects in brain regions typically involved in pain, except activation in a cluster in anterior cingulate cortex (ACC) was greater when upcoming stimulation was painful than when it was nonpainful. However, region-of-interest analyses in anterior insula (AI) and midcingulate cortex (MCC) indicated that the noxious nature of the upcoming stimulation, as well as the ability to affect it, influenced processing of ongoing stimulation in both of these regions. Activation in MCC, but not AI, also correlated with response times. Taken together, these studies contribute to the broader understanding of everyday decision making, and of how affective experiences such as pain and touch shape everyday decisions and behaviors. Stimulering av nervfibrer i huden kan ge upphov till starka känsloupplevelser. Skadliga eller potentiellt skadliga stimuli kan ge upphov till smärta, en obehaglig upplevelse som i sin tur orsakar lidande och har stora socioekonomiska konsekvenser. Beröring, å andra sidan, kan upplevas som behagligt och är en viktig del av sociala relationer. Förhållandevis lite kunskap finns dock om hur smärta och beröring påverkar vardagligt beslutsfattande. Blir vi otåliga av att uppleva smärta? Tar vi fler risker? Gör beröring oss snällare och mer tillitsfulla? I denna avhandling presenteras tre studier som försöker svara på denna typ av frågor. I den första studien fick deltagarna smärtsam värmestimulering samtidigt som de fattade beslut om pengar. Besluten involverade t.ex. att välja mellan en säker vinst på 50 kr eller att singla slant om att vinna 100 kr. Resultaten visade att smärta ökade risktagande för vinster, men inte för motsvarande förluster. Deltagare som upplevde smärta var även mer otåliga, dvs. de föredrog i större utsträckning snabba belöningar. I den andra studien fick deltagarna beröring med en mjuk pensel samtidigt som de fattade beslut. Lätt, smekande beröring aktiverar en särskild typ av nervfibrer, som tros signalera affektiva och socialt relevanta aspekter av beröring. Beröring ökar även utsöndringen av hormonet oxytocin, som sägs öka känslan av tillit till andra människor, även om de vetenskapliga bevisen för detta är motstridiga. Resultaten av studien visade ingen effekt av beröring på beslutsfattande. I den tredje studien undersöktes hjärnans aktivitet vid smärtsam stimulering. Vi vet sedan tidigare att hjärnan inte bara reagerar på det som händer just nu, utan att den även förbereder inför vad som kan komma att hända i framtiden. Deltagarna fick smärtsam eller icke-smärtsam värmestimulering samtidigt som de utförde en uppgift som innebar att de skulle trycka på en knapp för att förkorta en kommande värmestimulering. Resultaten visade att hjärnans bearbetning av pågående stimulering påverkades av huruvida nästkommande stimulering var smärtsam eller inte och huruvida den gick att påverka. Sammantaget bidrar dessa studier till en ökad förståelse av hur människor fattar beslut och hur upplevelser som smärta och beröring påverkar vardagligt beslutfattande och beteende. Smärta har en stark koppling till beteende, eftersom vi snabbt måste kunna agera för att undvika skada. Beröring, däremot, upplevs på olika sätt beroende på den sociala kontexten, vilket troligtvis också påverkar beröringens effekt på beteende.
Dr. John E. Sarno's groundbreaking research on TMS (Tension Myoneural Syndrome) reveals how stress and other psychological factors can cause back pain-and how you can be pain free without drugs, exercise, or surgery. Dr. Sarno's program has helped thousands of patients find relief from chronic back conditions. In this New York Times bestseller, Dr. Sarno teaches you how to identify stress and other psychological factors that cause back pain and demonstrates how to heal yourself--without drugs, surgery or exercise. Find out: Why self-motivated and successful people are prone to Tension Myoneural Syndrome (TMS) How anxiety and repressed anger trigger muscle spasms How people condition themselves to accept back pain as inevitable With case histories and the results of in-depth mind-body research, Dr. Sarno reveals how you can recognize the emotional roots of your TMS and sever the connections between mental and physical pain...and start recovering from back pain today.