Pathophysiology And Rational Pharmacotherapy Of Myocardial Ischemia

Author : G. Heusch
Publisher : Springer Science & Business Media
Page : 573 pages
File Size : 54,5 Mb
Release : 2013-06-29
Category : Medical
ISBN : 9783642541339

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Pathophysiology and Rational Pharmacotherapy of Myocardial Ischemia by G. Heusch Pdf

Ischemie heart disease is still the most frequent cause of death in the western world. There have been significant achievements in diagnostic procedures as well as in the medical, invasive, and surgiealtreatment ofischemieheart disease inrecent years. A variety ofdrugs are availablefor the pharmacotherapyofischemieheart disease, par ticularly nitrates, ß-blockers, and calcium-antagonists which are used as mono therapy or in various combinations. However, the selection of patients for a certain treatment, as weIl as the optimization of an individual treatment are still largely empirical. On the other hand, the recent advances in experimental cardiology emphasize the extremely complex and dynamie scenario of ischemic heart disease, involving endothelial damage, coagulation processes, metabolie and morphologie derangements, coronary constrictor mechanisms, blood flow redistribution, arrhythmogenesis, contraetile dysfunction during ischemia and reperfusion, and finally lack or presence of pain perception. Therefore, it appears desirable to close the gap between experimental and clinical cardiology and, thus, to provide a pathophysiologieal basis for rational cliniealdecisions with respect to diagnostic and therapeutic procedures. The idea for this book arose during the preparation of a seminar series on experi mental cardiology, when I found it diffieultto collect the pertinentinformation from textbooks of cardiology, physiology, pathology, and pharmacology, as well as from numerous review and original artieies on specifictopies. I am now very grateful that expert cliniealand experimental colleagues from around the world have joined me in the effort to provide a comprehensive textbook on the pathophysiology of myocar dial ischemia and its rational pharmacotherapy.

Author : Nabil El-Sherif,C. V. Ramana Reddy
Publisher : Elsevier
Page : 404 pages
File Size : 43,9 Mb
Release : 2013-10-22
Category : Health & Fitness
ISBN : 9781483277141

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The Pathophysiology and Pharmacotherapy of Myocardial Infarction by Nabil El-Sherif,C. V. Ramana Reddy Pdf

The Pathophysiology and Pharmacotherapy of Myocardial Infarction deals with the advances in the pathophysiology and pharmacotherapy of acute myocardial infarction and related complications. This book covers two major consequences—cardiac muscle dysfunction and cardiac electrical dysfunction. This text begins by reviewing the controversy surrounding the pathogenetic mechanisms of atheroma formation and its potential reversibility, including the status of coronary risk factors and benefits of primary prevention. The pathophysiologic mechanisms of pump failure and the current approach to its management are then deliberated, followed by a discussion on the rational use of vasodilators in post-infarction heart failure and pharmacotherapy of cardiogenic shock. The rationale for the interest in the role of coronary vasospasm and thrombolytic therapy for acute myocardial infarction is also covered. This publication concludes by reviewing the approaches for the management of post-infarction ventricular tachyarrhythmias and concept of secondary prevention of sudden cardiac death. This compilation is valuable to medical students, primary care physicians, and cardiovascular specialists.

Author : Gerd Heusch,Peter B. Corr
Publisher : Springer
Page : 0 pages
File Size : 43,9 Mb
Release : 1990
Category : Artères coronaires - Maladies - Chimiothérapie
ISBN : 0387913602

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Pathophysiology and Rational Pharmacotherapy of Myocardial Ischemia by Gerd Heusch,Peter B. Corr Pdf

Author : Abialbon Paul,Nishanthi Anandabaskar,Jayanthi Mathaiyan,Gerard Marshall Raj
Publisher : Springer Nature
Page : 1156 pages
File Size : 46,8 Mb
Release : 2021-03-13
Category : Medical
ISBN : 9789813360099

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Introduction to Basics of Pharmacology and Toxicology by Abialbon Paul,Nishanthi Anandabaskar,Jayanthi Mathaiyan,Gerard Marshall Raj Pdf

This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.

Author : Juan Carlos Kaski,David W. Holt
Publisher : Springer Science & Business Media
Page : 220 pages
File Size : 49,5 Mb
Release : 2013-03-09
Category : Medical
ISBN : 9789401723800

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Myocardial Damage by Juan Carlos Kaski,David W. Holt Pdf

The spectrum of unstable coronary syndromes has been the object of steadily increasing research particularly in respect of novel diagnostic and treatment modalities. Although the WHO criteria for the diagnosis of acute myocardial infarction have been known for decades, there is still much debate as to the proper use of these, especially the handling of biochemical markers. Traditional enzymes have limitations in diagnostic power and new markers have unclarified applicability with regard to standardisation of assays and decision limits. Furthermore, the growing understanding of the conception of minimal myocardial damage in the borderzone between unstable angina pectoris and myocardial infarction necessitates refinement in the definitions of the various entities within the kaleidoscope of acute myocardial ischaemia. There has been a strong impetus within the European Society of Cardiology to present this subject to a broad audience of cardiologists, and as a consequence the theme of biochemical markers has become an important constituent of the Education and Training Programmes of the Society. This book has fundamental implications for the overall comprehension of this complex area. This book on myocardial damage, compiled by international experts, will truly appeal to the basic scientist as well as the clinician searching for updated knowledge of the pathophysiology and risk stratification of unstable coronary syndromes.

Author : National Library of Medicine (U.S.)
Publisher : Unknown
Page : 1024 pages
File Size : 51,9 Mb
Release : 2024-06-29
Category : Medicine
ISBN : UOM:39015020571850

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Current Catalog by National Library of Medicine (U.S.) Pdf

First multi-year cumulation covers six years: 1965-70.

Author : National Library of Medicine (U.S.)
Publisher : Unknown
Page : 1032 pages
File Size : 53,7 Mb
Release : 1990
Category : Medicine
ISBN : MINN:31951D00422787B

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National Library of Medicine Current Catalog by National Library of Medicine (U.S.) Pdf

Author : Yoshihisa Kurachi,Andre Terzic,Michael V. Cohen
Publisher : Elsevier
Page : 1286 pages
File Size : 44,8 Mb
Release : 2000-10-09
Category : Science
ISBN : 9780080533889

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Heart Physiology and Pathophysiology by Yoshihisa Kurachi,Andre Terzic,Michael V. Cohen Pdf

Heart Physiology and Pathophysiology, 4E, provides the foundation for the scientific understanding of heart function and dysfunction, and bridges the gap between basic cardiovascular science and clinical cardiology. This comprehensive text covers all the important aspects of the heart and vascular system. The most important and relevant disorders are presented, with emphasis on the mechanisms involved. The first three editions of this book developed a reputation as the leading reference in cardiovascular science for researchers and academic cardiologists. This recent edition has been updated, expanded, and includes a number of new contributors. It has also been remodeled to expand its usage as a text reference for cardiology residents, practicing cardiologists, and graduate students. Key Features* The most comprehensive book available on this topic* Clear, concise, and complete coverage of all important aspects of cardiovascular physiology/pathophysiology* Completely updated version of the foremost reference on cardiovascular science, including new information on pathophysiology and electrophysiology* Useful tool in bridging the gap between basic science, pathophysiology, and clinical cardiology

Author : Timothy J Watson,Paul JL Ong,James E Tcheng
Publisher : Springer
Page : 338 pages
File Size : 55,7 Mb
Release : 2018-07-13
Category : Medical
ISBN : 9789811311147

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Primary Angioplasty by Timothy J Watson,Paul JL Ong,James E Tcheng Pdf

This book is open access under a CC BY 4.0 license. This quick-reference handbook offers a concise and practical review of key aspects of the treatment of ST-segment elevation myocardial infarction (STEMI) in the era of primary percutaneous coronary intervention (PPCI). In the context of STEMI, PPCI is the preferred mode of emergency revascularization. Access to PPCI is rapidly increasing and is now routinely practiced in both general and specialist hospitals and there has been a recent emphasis on developing STEMI networks to enhance and expedite the referral pathway. This coupled with concurrent developments to enhance the safety and efficacy of the PPCI procedure has heralded an era where STEMI interventions are increasingly considered an important subspecialty within interventional cardiology. Written by leading cardiologists who have been instrumental in the adoption of PPCI in their respective institutions, the book provides junior and senior cardiologists alike with insightful and thought-provoking tips and tricks to enhance the success of PPCI procedures, which may in turn translate into direct improvements in outcomes. The book is also relevant for healthcare providers and emergency department physicians.

Author : Gowraganahalli Jagadeesh,Pitchai Balakumar,Khin Maung-U
Publisher : Springer
Page : 1342 pages
File Size : 40,8 Mb
Release : 2015-05-06
Category : Medical
ISBN : 9783319159614

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Pathophysiology and Pharmacotherapy of Cardiovascular Disease by Gowraganahalli Jagadeesh,Pitchai Balakumar,Khin Maung-U Pdf

The present book covers the basic principles of cardiovascular physiology, pathophysiology and advanced pharmacology with particular emphasis on cellular mechanisms of drug action. It provides an update on the progress made in several aspects of cardiovascular diseases so that it might kindle scientists and clinicians alike in furthering basic and translational research. In addition, the book is expected to fill imperative gaps in understanding and optimally treating cardiovascular disease.

Author : Juan Carlos Kaski
Publisher : Springer
Page : 163 pages
File Size : 52,7 Mb
Release : 2016-08-15
Category : Medical
ISBN : 9783319411804

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Essentials in Stable Angina Pectoris by Juan Carlos Kaski Pdf

This title discusses the magnitude of the problem of angina pectoris. The author also goes on to describe the characteristics and clinical profile of patients with angina in a contemporary population. The different types and multiple mechanisms of angina pectoris are described, while the clinical presentation, typical and atypical features and complications (MI, HF) and clinical management and outcomes are evaluated. The author also evaluates the various antianginal therapies used in special populations: the elderly, post revascularised patients, patients with LVSD or HF, patients with CKD, patients with diabetes.

Author : Umashankar Lakshmanadoss
Publisher : BoD – Books on Demand
Page : 100 pages
File Size : 49,9 Mb
Release : 2020-07-01
Category : Medical
ISBN : 9781838805890

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Differential Diagnosis of Chest Pain by Umashankar Lakshmanadoss Pdf

This book aims to provide an excellent overview of the differential diagnosis and approach to chest pain in various clinical settings. This book is divided into two sections including the introduction and the approach to chest pain. Our introductory chapter starts with the basic principles of statistics and its application in various diagnostic modalities of heart disease. Our authors present a nice approach to patients presenting with chest pain in various scenarios. We have also included a chapter describing GERD, which could present as chest pain and another chapter describing aortic dissection, which is a life-threatening disease presenting with chest pain. We hope that this book will serve as an accessible handbook on the differential diagnosis of chest pain.

Author : Hans Michael Piper,C.J. Preusse
Publisher : Springer Science & Business Media
Page : 457 pages
File Size : 42,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401117135

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Ischemia-reperfusion in cardiac surgery by Hans Michael Piper,C.J. Preusse Pdf

In open heart surgery, protection of the myocardium against injury by ischemia-reperfusion is an issue of utmost clinical interest. The knowledge on the causal mechanisms of myocardial injury in ischemia-reperfusion has greatly progressed in recent years, both to clinical and experimental research. This book provides a critical and comprehensive overview on the current discussion of myocardial protection in cardiac experimental research and surgery. Leading groups from Europe, the U.S. and Japan have contributed reviews of their special fields. On the basic science side, major topics discussed are the mechanisms of stunning and lethal reperfusion injury, the role of the endothelium and leukocyte activation in postischemic myocardial dysfunction, and the differences between the adult and neonatal myocardium. On the clinical side, the major concepts and procedures for cardioplegic myocardial protection, their rationales, application and respective merits are discussed. In a third part of the book, possible approaches for the monitoring of myocardial injury during ischemia and reperfusion are evaluated, with particular attention to their intraoperative use. This book brings together the scientific discussions on ischemia-reperfusion in experimental cardiology and cardiac surgery, a task needed for a long time. It is of general interest for clinicians as well as research workers and students in the cardiac field.

Author : Anonim
Publisher : Unknown
Page : 666 pages
File Size : 46,6 Mb
Release : 2002
Category : Pharmacology
ISBN : UCR:31210016006510

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Canadian Journal of Physiology and Pharmacology by Anonim Pdf

Author : Stephan Gielen,Guy De Backer,Massimo Piepoli,David Wood
Publisher : European Society of Cardiology
Page : 369 pages
File Size : 41,7 Mb
Release : 2015
Category : Medical
ISBN : 9780199656653

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The ESC Textbook of Preventive Cardiology by Stephan Gielen,Guy De Backer,Massimo Piepoli,David Wood Pdf

"EACPR, European Association for Cardiovascular Prevention and Rehabilitation -- European Society of Cardiology."