Pathways Protocols

Author : Kakoli Bose
Publisher : Springer
Page : 245 pages
File Size : 53,7 Mb
Release : 2015-08-06
Category : Science
ISBN : 9783319194974

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Proteases in Apoptosis: Pathways, Protocols and Translational Advances by Kakoli Bose Pdf

This book provides a comprehensive overview of the proteases involved in programmed cell death. It presents a focused yet extensive discussion on proteolytic enzymes such as caspases, HtrAs, granzymes, calpains and cathepsins as well as laboratory protocols related to enzymology and apoptosis. Mouse model systems and non-invasive imaging techniques in apoptosis-related diseases such as cancer and neurodegeneration are also covered in this book. While slowly unravelling the complexities of apoptosis in chapter one, the next three chapters individually elaborate on different classes of proteases that play key roles in the initiation, progression and execution of programmed cell death. The last two chapters complete this discussion by describing different laboratory methodologies and therapeutic advances involving apoptotic proteases. Protocols portraying in vitro and ex vivo colorimetric and fluorescence-based enzyme kinetic studies as well as cell death assays are explained in the fifth chapter. Preclinical in vivo models and non-invasive imaging in apoptosis to understand the complexities of disease progression and their contribution toward therapeutics is recounted in the last chapter. The book spans topics related to both fundamental and applied biology. It would therefore be equally appealing and informative to scientists working in the field of apoptosis and those who are investigating mechanisms of proteases and enzymes in general. The protocols would certainly benefit both graduate and undergraduate students working in the related fields and provide useful leads for drug design to translational biologists involved in neurodegeneration and cancer research.

Author : OECD,World Health Organization
Publisher : OECD Publishing
Page : 128 pages
File Size : 52,8 Mb
Release : 2019-10-17
Category : Electronic
ISBN : 9789264805903

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Improving Healthcare Quality in Europe Characteristics, Effectiveness and Implementation of Different Strategies by OECD,World Health Organization Pdf

This volume, developed by the Observatory together with OECD, provides an overall conceptual framework for understanding and applying strategies aimed at improving quality of care. Crucially, it summarizes available evidence on different quality strategies and provides recommendations for their implementation. This book is intended to help policy-makers to understand concepts of quality and to support them to evaluate single strategies and combinations of strategies.

Author : Kathryn de Luc,Julian Todd
Publisher : CRC Press
Page : 222 pages
File Size : 46,8 Mb
Release : 2020-01-30
Category : Medical
ISBN : 9781315344492

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e-Pathways by Kathryn de Luc,Julian Todd Pdf

Care Pathways are being developed throughout the health service to improve the quality and effectiveness of care. Are they being developed efficiently and making the most of the latest clinical computing systems? This is the first practical guide on how Information Technology and systems methods can support the development, implementation and maintenance of Care Pathways. Case studies throughout highlight team approaches to facilitation, clinical knowledge management, process analysis and redesign, and computerisation - providing insights into how e-Pathways can be used to support high quality patient care. The information is presented in an easy-to-read style, and requires no prior knowledge of IT systems. Doctors, nurses and managers throughout primary and secondary care, as well as healthcare information technology specialists and suppliers will find this to be essential reading.

Author : Anonim
Publisher : Unknown
Page : 304 pages
File Size : 42,7 Mb
Release : 2015
Category : Cytology
ISBN : OCLC:965302242

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CST Guide by Anonim Pdf

Author : Christopher P. Cannon,Patrick T. O'Gara
Publisher : Lippincott Williams & Wilkins
Page : 340 pages
File Size : 50,6 Mb
Release : 2007
Category : Medical
ISBN : 0781794390

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Critical Pathways in Cardiovascular Medicine by Christopher P. Cannon,Patrick T. O'Gara Pdf

Full-text medical e-book.

Author : Michael Krogh Jensen,Jay D. Keasling
Publisher : Humana Press
Page : 354 pages
File Size : 44,9 Mb
Release : 2017-11-24
Category : Medical
ISBN : 1493972944

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Synthetic Metabolic Pathways by Michael Krogh Jensen,Jay D. Keasling Pdf

This volume outlines key steps associated with the design, building, and testing of synthetic metabolic pathways for optimal cell factory performance and robustness, and illustrates how data-driven learning from these steps can be used for rational cost-effective engineering of cell factories with improved performance. Chapters are divided into four sections focusing on the four steps of the iterative design-build-test-learn cycle related to modern cell factory engineering. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Synthetic Metabolic Pathways: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Author : Thomas Platz
Publisher : Springer Nature
Page : 284 pages
File Size : 55,5 Mb
Release : 2021-01-14
Category : Medical
ISBN : 9783030585051

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Clinical Pathways in Stroke Rehabilitation by Thomas Platz Pdf

This open access book focuses on practical clinical problems that are frequently encountered in stroke rehabilitation. Consequences of diseases, e.g. impairments and activity limitations, are addressed in rehabilitation with the overall goal to reduce disability and promote participation. Based on the available best external evidence, clinical pathways are described for stroke rehabilitation bridging the gap between clinical evidence and clinical decision-making. The clinical pathways answer the questions which rehabilitation treatment options are beneficial to overcome specific impairment constellations and activity limitations and are well acceptable to stroke survivors, as well as when and in which settings to provide rehabilitation over the course of recovery post stroke. Each chapter starts with a description of the clinical problem encountered. This is followed by a systematic, but concise review of the evidence (RCTs, systematic reviews and meta-analyses) that is relevant for clinical decision-making, and comments on assessment, therapy (training, technology, medication), and the use of technical aids as appropriate. Based on these summaries, clinical algorithms / pathways are provided and the main clinical-decision situations are portrayed. The book is invaluable for all neurorehabilitation team members, clinicians, nurses, and therapists in neurology, physical medicine and rehabilitation, and related fields. It is a World Federation for NeuroRehabilitation (WFNR) educational initiative, bridging the gap between the rapidly expanding clinical research in stroke rehabilitation and clinical practice across societies and continents. It can be used for both clinical decision-making for individuals and as well as clinical background knowledge for stroke rehabilitation service development initiatives.

Author : Terri Janke
Publisher : Unknown
Page : 123 pages
File Size : 55,9 Mb
Release : 2009
Category : Performing Arts
ISBN : 1920998098

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Pathways & Protocols by Terri Janke Pdf

"This practical guide is essential reading for all filmmakers shooting in Australia. Research and written by lawyer Terri Janke, Pathways & Protocols provides advice about the ethical and legal issues involved in transferring Indigenous cultural material to the screen. Whether shooting in country or city, with an Indigenous cast or not, practitioners of film, TV and digital media projects are encouraged to recognise and respect Indigenous people's images, knowledge, stories and land in the production of audiovisual material."--Back cover.

Author : Patricia C. Dykes
Publisher : Jones & Bartlett Learning
Page : 308 pages
File Size : 48,8 Mb
Release : 1998
Category : Medical protocols
ISBN : 0834211564

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Psychiatric Clinical Pathways by Patricia C. Dykes Pdf

The only reference tool of its kind for psychiatric health care professionals and agencies, Psychiatric Clinical Pathways: An Interdisciplinary Approach gives a wealth of practical guidance and useful real-world models you can put to work immediately. You and your staff will discover the many ways clinical pathways can be used to deliver cost-effective, quality care in a variety of settings. You'll benefit from useful models of outcomes-based care delivery systems, and practical guidelines For The delivery of quality health care and continuous quality improvement. This book is packed with information you can use immediately, including a bonus Clinical Pathways Diskette -- packed with formats and checklists your can customize to meet your needs.

Author : Institute of Medicine,Board on Health Care Services,Committee on Standards for Developing Trustworthy Clinical Practice Guidelines
Publisher : National Academies Press
Page : 217 pages
File Size : 40,9 Mb
Release : 2011-06-16
Category : Medical
ISBN : 9780309216463

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Clinical Practice Guidelines We Can Trust by Institute of Medicine,Board on Health Care Services,Committee on Standards for Developing Trustworthy Clinical Practice Guidelines Pdf

Advances in medical, biomedical and health services research have reduced the level of uncertainty in clinical practice. Clinical practice guidelines (CPGs) complement this progress by establishing standards of care backed by strong scientific evidence. CPGs are statements that include recommendations intended to optimize patient care. These statements are informed by a systematic review of evidence and an assessment of the benefits and costs of alternative care options. Clinical Practice Guidelines We Can Trust examines the current state of clinical practice guidelines and how they can be improved to enhance healthcare quality and patient outcomes. Clinical practice guidelines now are ubiquitous in our healthcare system. The Guidelines International Network (GIN) database currently lists more than 3,700 guidelines from 39 countries. Developing guidelines presents a number of challenges including lack of transparent methodological practices, difficulty reconciling conflicting guidelines, and conflicts of interest. Clinical Practice Guidelines We Can Trust explores questions surrounding the quality of CPG development processes and the establishment of standards. It proposes eight standards for developing trustworthy clinical practice guidelines emphasizing transparency; management of conflict of interest ; systematic review-guideline development intersection; establishing evidence foundations for and rating strength of guideline recommendations; articulation of recommendations; external review; and updating. Clinical Practice Guidelines We Can Trust shows how clinical practice guidelines can enhance clinician and patient decision-making by translating complex scientific research findings into recommendations for clinical practice that are relevant to the individual patient encounter, instead of implementing a one size fits all approach to patient care. This book contains information directly related to the work of the Agency for Healthcare Research and Quality (AHRQ), as well as various Congressional staff and policymakers. It is a vital resource for medical specialty societies, disease advocacy groups, health professionals, private and international organizations that develop or use clinical practice guidelines, consumers, clinicians, and payers.

Author : Valerie Bayliss,Rachel Locke,Elizabeth Salter
Publisher : John Wiley & Sons
Page : 216 pages
File Size : 55,5 Mb
Release : 2009-04-15
Category : Medical
ISBN : 0470744189

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Continence Care Pathways by Valerie Bayliss,Rachel Locke,Elizabeth Salter Pdf

This practical and timely book gives all the information required to implement care pathways for continence so that patients at all levels can have access to evidence based support and advice. It guides the reader through the pathway experience offering suggestions and advice on how to implement them locally, avoiding pitfalls, and incorporating case studies from Trusts who implement them. Written by experts in the field, it brings evidence and practice together, offering an alternative approach to assessment.

Author : National Collaborating Centre for Mental Health (Great Britain)
Publisher : RCPsych Publications
Page : 316 pages
File Size : 51,6 Mb
Release : 2011
Category : Health services accessibility
ISBN : 1908020318

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Common Mental Health Disorders by National Collaborating Centre for Mental Health (Great Britain) Pdf

Bringing together treatment and referral advice from existing guidelines, this text aims to improve access to services and recognition of common mental health disorders in adults and provide advice on the principles that need to be adopted to develop appropriate referral and local care pathways.

Author : Steve Loft
Publisher : Unknown
Page : 0 pages
File Size : 42,5 Mb
Release : 2014
Category : Art
ISBN : 1552387062

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Coded Territories by Steve Loft Pdf

This collection of essays provides a historical and contemporary context for Indigenous new media arts practice in Canada. The writers are established artists, scholars, and curators who cover thematic concepts and underlying approaches to new media from a distinctly Indigenous perspective. Through discourse and narrative analysis, the writers discuss a number of topics ranging from how Indigenous worldviews inform unique approaches to new media arts practice to their own work and specific contemporary works. Contributors include: Archer Pechawis, Jackson 2Bears, Jason Edward Lewis, Steven Foster, Candice Hopkins, and Cheryl L'Hirondelle.

Author : Anonim
Publisher : Elsevier
Page : 813 pages
File Size : 47,5 Mb
Release : 2001-12-18
Category : Science
ISBN : 9780080496924

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G Protein Pathways, Part B: G Proteins and Their Regulators by Anonim Pdf

This volume covers topics such as the structure and identification of functional domains of G proteins, and activation of G proteins by receptors or other regulators. The text takes an integrated approach to studying common experimental questions at many different levels related to G proteins. Methods related to G proteins using molecular modeling, systems biology, protein engineering, protein biochemistry, cell biology, and physiology are all accessible in the same volume. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today truly an essential publication for researchers in all fields of life sciences.

Author : C. Timmermann,E. Toon
Publisher : Springer
Page : 270 pages
File Size : 49,9 Mb
Release : 2012-10-10
Category : Science
ISBN : 9781137272089

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Cancer Patients, Cancer Pathways by C. Timmermann,E. Toon Pdf

Eleven essays by historians and sociologists examine cancer research and treatment as everyday practice in post-war Europe and North America. These are not stories of inevitable medical progress and obstacles overcome, but of historical contingencies, cultural differences, hope, and often disappointed expectations.