Pediatric Lymphomas Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Pediatric Lymphomas book. This book definitely worth reading, it is an incredibly well-written.
Howard J. Weinstein,Melissa M. Hudson,Michael P. Link
Author : Howard J. Weinstein,Melissa M. Hudson,Michael P. Link Publisher : Springer Science & Business Media Page : 296 pages File Size : 49,8 Mb Release : 2007-01-20 Category : Medical ISBN : 9783540687535
Pediatric Lymphomas by Howard J. Weinstein,Melissa M. Hudson,Michael P. Link Pdf
This is a comprehensive textbook of Hodgkin's and non-Hodgkin's lymphomas written by leaders in the field of childhood lymphomas. It includes clinical, pathologic and molecular biology of each subtype of lymphoma. The pathology chapters are comprehensive and include excellent photographs. The book is at the level of subspecialists in pediatric hematology and oncology, radiation oncology, pediatric surgery and hematopathology.
Non-Hodgkin's Lymphoma in Childhood and Adolescence by Oussama Abla,Andishe Attarbaschi Pdf
This text provides a state-of-the-art overview on Non-Hodgkin's lymphoma (NHL) in children and adolescents. The volume is divided into seven sections, each of which focuses on a critical component of pediatric NHL, including history and epidemiology, pathology and molecular biology, disease evaluation and response, common and rare sub-types of NHL, and current and novel treatment strategies. The text also comprehensively reviews the late effects of treatment, quality of patient life, and NHL treatment in countries with limited resources. Written by experts in the field, Non-Hodgkin's Lymphoma in Childhood and Adolescence is a valuable resource for clinicians and practitioners who treat children and adolescents with NHL.
Author : William K. Oh,Ajai Chari Publisher : John Wiley & Sons Page : 632 pages File Size : 51,5 Mb Release : 2019-09-30 Category : Medical ISBN : 9781119189558
The Mount Sinai Expert Guides provide quick access to point-of-care specialist clinical information for physicians across a range of therapeutic areas. For each specialty area, the guides emphasize: Common pitfalls in diagnosis and management How to prevent complications Diagnostic and treatment algorithms Key scientific trials Evidence-based clinical content Major society guidelines in order to summarize the very latest in diagnosis and management of diseases and related symptoms. Edited by renowned specialists from the Icahn School of Medicine at Mount Sinai, key faculty members provide the content for all chapters. To ensure consistency within each book and the series as a whole, chapters follow a unified structure throughout. Bonus features such as online case studies with related questions for self-assessment, key patient advice, and ICD codes are provided via the series companion website. Each guide also has its own mobile app available for purchase, allowing you rapid access to the key features wherever you may be.
Childhood Acute Lymphoblastic Leukemia by Ajay Vora Pdf
This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.
Cancer Genomics by Nathanael G. Bailey,Thomas Gross,Megan S. Lim Pdf
Lymphomas account for approximately 10% of childhood malignancies. Pediatric lymphomas are typically aggressive: lymphoblastic lymphoma, Burkitt lymphoma (BL), diffuse large B-cell lymphoma (DLBCL), and anaplastic large cell lymphoma (ALCL) are among the most common pediatric lymphoma subtypes. The genetic basis of these neoplasms is beginning to be understood. Lymphoblastic lymphomas arise through a variety of genetic pathways, dependent upon B- or T-progenitor origin. Aggressive B-cell lymphomas (BL and DLBCL) commonly arise secondary to errors that occur during physiologic B-cell development. BL is characterized by MYC translocation with an immunoglobulin locus enhancer. This lesion may also be present in DLBCL, particularly in children, but DLBCLs often have mutations of a variety of other genes, such as BCL6. DLBCL may be separated into germinal center B-cell-like (GCB) and activated B-cell-like groups. Pediatric DLBCL are more commonly in the GCB category than are adult DLBCL. Adult DLBCL has a tendency toward increased genomic complexity compared with pediatric DLBCL. ALCL is a T-cell lymphoma that is typically characterized by ALK fusions, most commonly with NPM. Genomic profiling has identified areas of recurrent genetic gains and losses in ALCL. Understanding the underlying genetic basis of lymphoma provides hope for the development of more targeted therapies for this group of diseases. However, further investigation of the lymphoma genome is necessary, particularly in pediatric patients.
Pediatric Radiation Oncology by Thomas E. Merchant,Rolf-Dieter Kortmann Pdf
This book presents the most up-to-date and innovative information on the targeting and treatment of a wide range of childhood cancers by means of radiation therapy. Written by global experts in pediatric radiation oncology, it documents in detail the treatment regimens appropriate to each disease, highlighting the recent advances that promise to improve rates of survival and cure. The use of image-guided and intensity-modulated radiation therapy is clearly described, and careful attention is also devoted to the roles of proton therapy, stereotactic radiosurgery, stereotactic fractionated radiosurgery, and modulated arc radiotherapy. Separate chapters address localization and verification procedures and anesthesia; pediatric radiation oncology in the palliative care setting; and aspects that are especially relevant in low- and medium-income countries. Beyond clinical radiation oncology, relevant information is provided on radiation physics. The book concludes by examining future directions in the field.
National Academies of Sciences Engineering and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on Childhood Cancers and Disability
Author : National Academies of Sciences Engineering and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on Childhood Cancers and Disability Publisher : Unknown Page : 128 pages File Size : 46,5 Mb Release : 2021-09-09 Category : Electronic ISBN : 0309683491
Childhood Cancer and Functional Impacts Across the Care Continuum by National Academies of Sciences Engineering and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on Childhood Cancers and Disability Pdf
Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.
This well-illustrated monograph presents a comprehensive description of Fine-Needle Cytology (FNC), including technical procedures and ancillary techniques, applied to the lymph node (LN). Possibilities and limitations are highlighted to produce accurate cytological diagnosis of LN and cytological criteria, and to be exploited for extra-nodal lymphoproliferative processes. The normal LN structure and corresponding cytological patterns are described. Cytological, phenotypical, and molecular features are reviewed along with diagnostic criteria for various medical conditions such as lymphadenitis and lymphadenopathies, Hodgkin and Non-Hodgkin lymphoma, pediatric lymphoadenopaties, immunodeficiency-associated lymphoproliferative disorders, extra-nodal lymphoproliferative processes, metastases, and other non-lymphomatous processes. LN-FNC requires knowledge of hemathopathology and imaging techniques, as well as dexterity with FNC performing, smearing, and material management. Rapid on-site evaluation (ROSE), the choice of ancillary techniques and molecular procedures case by case are required to produce accurate and comprehensive diagnosis. This book will help cytopathologists to conduct these tasks in various organs and clinical contexts. LN-FNC requires knowledge of hemathopathology and imaging techniques, as well as dexterity with FNC performing, smearing, and material management. Rapid on-site evaluation (ROSE), the choice of ancillary techniques and molecular procedures case by case are required to produce accurate and comprehensive diagnosis. This book will help cytopathologists to conduct these tasks in various organs and clinical contexts.
Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Publisher : John Wiley & Sons Page : 2008 pages File Size : 50,5 Mb Release : 2017-03-10 Category : Medical ISBN : 9781119000846
Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Harper's Textbook of Pediatric Dermatology by Peter H. Hoeger,Veronica Kinsler,Albert C. Yan,Christine Bodemer,Margarita Larralde,David Luk,Vibhu Mendiratta,Diana Purvis Pdf
A consummate classic with a fresh approach to pediatric dermatology Children ́s skin is different. Maturation affects the epidermal barrier, the cutaneous microbiome, adnexal structures, vasculature, and transcutaneous absorption of drugs. The immature skin is more susceptible to pathogens and environmental disruption. Many genetic disorders are either present at birth or manifest early in childhood. Skin diseases thus present differently in children than in adults. Pediatric dermatology has seen significant advances over the last decade, particularly in the field of molecular genetics research, which has furthered our understanding of the pathogenesis of many skin diseases and the development of new approaches to treatment. This fourth edition of the Harper classic provides state-of-the-art information on all aspects of skin disease in children. It covers the diagnosis and treatment of all conditions - both common and rare - with a consistently evidence-based approach. Existing content has been refreshed and fully updated to reflect emerging thinking and to incorporate the latest in research and clinical data - especially at the genetic level. This new fourth edition includes: Greater focus on the genetics behind skin disease, including new genes/genodermatoses, progress in genetic analysis, and stem cell transplants Increased coverage of lasers and other technologies used to treat skin disease More summary tables, learning points, tables of differential diagnosis, and clinical algorithms for diagnosis and management Additional online features, including patient information links and multiple choice questions Harper's Textbook of Pediatric Dermatology delivers crucial clinical insights and up-to-date research information that spans the breadth of the field. As the most comprehensive reference book on this subject available, this revised fourth edition will support and guide the daily practice of both dermatologists and pediatricians across the world.
Histiocytic Disorders by Oussama Abla,Gritta Janka Pdf
This volume provides a comprehensive and world-class review of the field of histiocytic neoplasms and hemophagocytic lymphohistiocytosis (HLH). It reviews all the advances in the field of histiocytoses during the last ten years, particularly with regards to the genomic findings in LCH and other histiocytic neoplasms and the new suggested classification of the histiocytic disorders. Additionally, it features a state-of-the art update on the most recent treatment strategies for LCH, including the results of the last LCH-III international trial, salvage therapies such as reduced-intensity conditioning (RIC) stem cell transplant (SCT), and targeted therapies with BRAF and MEK inhibitors, as well as the challenging cases of CNS-neurodegenerative LCH and its therapeutic perspectives. For primary and secondary HLH the book updates the most recent genetic and pathophysiological findings, including macrophage-activation syndrome (MAS), and includes a special chapter on HLH in adults. Treatment chapters encompass therapy for newly diagnosed HLH and refractory disease as well as stem-cell transplantation and novel therapies. The text also highlights the most recent advances in the treatment of the uncommon histiocytic disorders, such as Erdheim-Chester disease (ECD), Juvenile xanthogranuloma (JXG) and JXG-like conditions, Rosai-Dorfman disease (RDD), and the very rare malignant histiocytoses. Written by international experts in the field, Histiocytic Disorders is a valuable resource for clinicians, researchers, fellows and residents who are interested in or manage histiocytic disorders in children and adults.
Frederick L, Greene,David L. Page,Irvin D. Fleming,April G. Fritz,Charles M. Balch,Daniel G. Haller,Monica Morrow
Author : Frederick L, Greene,David L. Page,Irvin D. Fleming,April G. Fritz,Charles M. Balch,Daniel G. Haller,Monica Morrow Publisher : Springer Science & Business Media Page : 386 pages File Size : 40,5 Mb Release : 2013-11-21 Category : Medical ISBN : 9781475736564
AJCC Cancer Staging Manual by Frederick L, Greene,David L. Page,Irvin D. Fleming,April G. Fritz,Charles M. Balch,Daniel G. Haller,Monica Morrow Pdf
The American Joint Committee on Cancer's Cancer Staging Manual is used by physicians throughout the world to diagnose cancer and determine the extent to which cancer has progressed. All of the TNM staging information included in this Sixth Edition is uniform between the AJCC (American Joint Committee on Cancer) and the UICC (International Union Against Cancer). In addition to the information found in the Handbook, the Manual provides standardized data forms for each anatomic site, which can be utilized as permanent patient records, enabling clinicians and cancer research scientists to maintain consistency in evaluating the efficacy of diagnosis and treatment. The CD-ROM packaged with each Manual contains printable copies of each of the book’s 45 Staging Forms.
An Illustrated Guide to Pediatric Surgery by Ahmed H. Al-Salem Pdf
Written in a simple point by point style for ease of use, this volume covers all aspects of pediatric surgery with emphasis on important points for diagnosis and management. Each chapter covers a topic with emphasis on the most common conditions in neonatal and general pediatric surgery. The text is well illustrated with clinical, operative, radiological, and histopathological color figures and illustrations. The book also presents some of the rare conditions encountered in pediatric surgery, as well as common pediatric urology conditions. An Illustrated Guide to Pediatric Surgery is a useful reference to pediatric surgeons, specialists, fellows and residents, as well as general surgeons, pediatricians, neonatologists, medical students and interns interested in pediatric surgery.