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Author : Kevin Brown
Publisher : The History Press
Page : 472 pages
File Size : 41,9 Mb
Release : 2005-09-15
Category : Biography & Autobiography
ISBN : 9780750953474
The history of penicillin.
Author : Eric Lax
Publisher : Henry Holt and Company
Page : 320 pages
File Size : 51,6 Mb
Release : 2015-06-02
Category : Medical
ISBN : 9781627796446
The untold story of the discovery of the first wonder drug, the men who led the way, and how it changed the modern world The discovery of penicillin in 1928 ushered in a new age in medicine. But it took a team of Oxford scientists headed by Howard Florey and Ernst Chain four more years to develop it as the first antibiotic, and the most important family of drugs in the twentieth century. At once the world was transformed-major bacterial scourges such as blood poisoning and pneumonia, scarlet fever and diphtheria, gonorrhea and syphilis were defeated as penicillin helped to foster not only a medical revolution but a sexual one as well. In his wonderfully engaging book, acclaimed author Eric Lax tells the real story behind the discovery and why it took so long to develop the drug. He reveals the reasons why credit for penicillin was misplaced, and why this astonishing achievement garnered a Nobel Prize but no financial rewards for Alexander Fleming, Florey, and his team. The Mold in Dr. Florey's Coat is the compelling story of the passage of medicine from one era to the next and of the eccentric individuals whose participation in this extraordinary accomplishment has, until now, remained largely unknown.
Author : Robert Bud
Publisher : OUP Oxford
Page : 342 pages
File Size : 55,8 Mb
Release : 2007
Category : History
ISBN : 9780199254064
The author sets the discovery and use of penicillin in the broader context of social and cultural changes across the world. He examines the drug's contributions to medicine and agriculture, and investigates the global spread of resistant bacteria as antibiotic use continues to rise.
Author : Anonim
Publisher : Academic Press
Page : 288 pages
File Size : 42,5 Mb
Release : 2019-07-13
Category : Medical
ISBN : 9780128173176
Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series
Author : Ted Gottfried
Publisher : Unknown
Page : 112 pages
File Size : 44,9 Mb
Release : 1997
Category : Bacteriologists
ISBN : 0531113701
A biography of the British bacteriologist, born in Scotland, who was knighted and awarded the 1945 Nobel Prize in medicine for discovering penicillin.
Author : Jan Payne,Steven Wilder
Publisher : Enslow Publishing, LLC
Page : 50 pages
File Size : 51,7 Mb
Release : 2016-07-15
Category : Juvenile Nonfiction
ISBN : 9780766079212
Science has made some incredible things possible. Many medications, technology, and scientific theory are well known, while others remain inventions of the imagination. Through engaging text enhanced by whimsical color illustrations and a fun quiz, readers can discover just how much they know about the history of science.
Author : María Jesús Santesmases
Publisher : Springer
Page : 239 pages
File Size : 41,7 Mb
Release : 2017-12-18
Category : Science
ISBN : 9783319697185
This book reconstructs the early circulation of penicillin in Spain, a country exhausted by civil war (1936–1939), and oppressed by Franco’s dictatorship. Embedded in the post-war recovery, penicillin’s voyages through time and across geographies – professional, political and social – were both material and symbolic. This powerful antimicrobial captivated the imagination of the general public, medical practice, science and industry, creating high expectations among patients, who at times experienced little or no effect. Penicillin’s lack of efficacy against some microbes fueled the search for new wonder drugs and sustained a decades-long research agenda built on the post-war concept of development through scientific and technological achievements. This historical reconstruction of the social life of penicillin between the 1940s and 1980s – through the dictatorship to democratic transition – explores political, public, medical, experimental and gender issues, and the rise of antibiotic resistance.
Author : M. Lindsay Grayson,Sara E. Cosgrove,Suzanne Crowe,William Hope,James S. McCarthy,John Mills,Johan W. Mouton,David L. Paterson
Publisher : CRC Press
Page : 4894 pages
File Size : 47,8 Mb
Release : 2017-10-02
Category : Medical
ISBN : 9781498747967
Kucers’ The Use of Antibiotics is the definitive, internationally-authored reference, providing everything that the infectious diseases specialist and prescriber needs to know about antimicrobials in this vast and rapidly developing field. The much-expanded Seventh Edition comprises 4800 pages in 3 volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into four sections - antibiotics, anti-fungal drugs, anti-parasitic drugs, and anti-viral drugs - and is highly structured for ease of reference. Each chapter is organized in a consistent format, covering susceptibility, formulations and dosing (adult and pediatric), pharmacokinetics and pharmacodynamics, toxicity, and drug distribution, with detailed discussion regarding clinical uses - a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with expert contributors representing Europe, Africa, Asia, Australia, South America, the US, and Canada, the Seventh Edition adopts a truly global approach. It remains invaluable for anyone using antimicrobial agents in their clinical practice and provides, in a systematic and concise manner, all the information required when prescribing an antimicrobial to treat infection.
Author : Hans T. Clarke
Publisher : Princeton University Press
Page : 1116 pages
File Size : 40,9 Mb
Release : 2015-12-08
Category : Medical
ISBN : 9781400874910
This book makes available, for interested scientists to procure, absorb, and evaluate, the vast body of information on the research and results of the work on the chemistry of penicillin done in England and the United States during the war. The National Academy of Sciences arranged for the preparation of this summary, Dr. H. T. Clarke and Dr. J. R. Johnson representing the United States on the editorial board, and Sir Robert Robinson representing Britain. The body of the work was prepared by more than 60 outstanding biochemists and biophysicists, who describe the phases of research to which they contributed the most. The work of 23 academic, medical, industrial, and government laboratories is reported. Originally published in 1949. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
Author : Guy De la Bédoyère
Publisher : Evans Brothers
Page : 56 pages
File Size : 55,7 Mb
Release : 2005
Category : Juvenile Nonfiction
ISBN : 0237527391
One of a series of titles which looks at some key scientific advances of the last century, how they came about, and their repercussions.
Author : Anonim
Publisher : DIANE Publishing
Page : 188 pages
File Size : 53,9 Mb
Release : 1995
Category : Drug resistance in microorganisms
ISBN : 9781428920255
Author : John C. Sheehan
Publisher : MIT Press (MA)
Page : 224 pages
File Size : 40,7 Mb
Release : 1984-03-01
Category : Medical
ISBN : 0262690853
The laboratory synthesis of penicillin, with its intractable beta-lactam structure or "enchanted ring," proved to be one of the most difficult problems ever undertaken by organic chemists. In this book, John Sheehan the man who succeeded in synthesizing penicillin after others had given up, recounts the discovery and development of this remarkable drug.
Author : Hyman J. Zimmerman
Publisher : Lippincott Williams & Wilkins
Page : 848 pages
File Size : 46,9 Mb
Release : 1999
Category : Medical
ISBN : 0781719526
Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
Author : Céline Pulcini,Onder Ergonul,Füsun Can,Bojana Beović
Publisher : Academic Press
Page : 394 pages
File Size : 49,7 Mb
Release : 2017-04-05
Category : Science
ISBN : 9780128134610
Antimicrobial Stewardship (AMS), Volume Two includes the experience of ESGAP workshops and courses on antibiotic stewardship since 2012. It combines clinical and laboratory information about AMS, with a focus on human medicine. The ESCMID study group on antibiotic policies (ESGAP) is one of the most productive groups in the field, organizing courses and workshops. This book is an ideal tool for the participants of these workshops. With short chapters (around 1500 words) written on different topics, the authors insisted on the following points: A ‘hands on’, practical approach, tips to increase success, a description of the most common mistakes, a global picture (out- and inpatient settings, all countries) and a short list of 10-20 landmark references. Focuses on the most recent antimicrobial stewardship strategies Provides a detailed description of laboratory support Offers a balanced synthesis of basic and clinical sciences for each individual case, presenting clinical courses of the cases in parallel with the pathogenesis and detailed microbiological information for each infection Describes the prevalence and incidence of the global issues and current therapeutic approaches Presents the measures for infection control
Author : Jack Botting
Publisher : Open Book Publishers
Page : 244 pages
File Size : 50,6 Mb
Release : 2015-05-04
Category : Medical
ISBN : 9781783741175
Animals and Medicine: The Contribution of Animal Experiments to the Control of Disease offers a detailed, scholarly historical review of the critical role animal experiments have played in advancing medical knowledge. Laboratory animals have been essential to this progress, and the knowledge gained has saved countless lives—both human and animal. Unfortunately, those opposed to using animals in research have often employed doctored evidence to suggest that the practice has impeded medical progress. This volume presents the articles Jack Botting wrote for the Research Defence Society News from 1991 to 1996, papers which provided scientists with the information needed to rebut such claims. Collected, they can now reach a wider readership interested in understanding the part of animal experiments in the history of medicine—from the discovery of key vaccines to the advancement of research on a range of diseases, among them hypertension, kidney failure and cancer.This book is essential reading for anyone curious about the role of animal experimentation in the history of science from the nineteenth century to the present.