Perspectives Of Stem Cells

Author : Institute of Medicine,Board on Neuroscience and Behavioral Health,National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on the Biological and Biomedical Applications of Stem Cell Research
Publisher : National Academies Press
Page : 112 pages
File Size : 44,7 Mb
Release : 2002-01-25
Category : Science
ISBN : 9780309170420

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Stem Cells and the Future of Regenerative Medicine by Institute of Medicine,Board on Neuroscience and Behavioral Health,National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on the Biological and Biomedical Applications of Stem Cell Research Pdf

Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.

Author : Lars Østnor
Publisher : Springer Science & Business Media
Page : 255 pages
File Size : 40,7 Mb
Release : 2008-04-03
Category : Science
ISBN : 9781402069895

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Stem Cells, Human Embryos and Ethics by Lars Østnor Pdf

Is it acceptable from an ethical point of view to use stem cells from human embryos for scientific research and clinical therapy? And what are the weaknesses and strengths of various opinions and positions when they are critically evaluated? These are the main problems dealt with in this book. The various chapters as a whole give a comprehensive, many-sided and balanced discussion of the subject. The book contains contributions from biological, medical, social, political, philosophical and theological perspectives. The authors have been chosen because of their professional competence, many of them being respected scholars on a top international level. They give an updated contribution from their own discipline in order to enlighten the different aspects of the common theme. The authors cover various positions and evaluations with regard to the question of the use of embryonic stem cells for research and therapy. The book is written for several audiences: a) scholars and professionals working with stem cell research or with the ethical questions arising from this field (people from biology, medicine, law, philosophy, theology etc.), b) advanced and graduate students within the same professional disciplines and c) politicians and the general public interested in the burning ethical problems which are intensively debated in many countries.

Author : Diana Kitala,Ana Colette Maurício
Publisher : BoD – Books on Demand
Page : 180 pages
File Size : 46,7 Mb
Release : 2021-04-14
Category : Technology & Engineering
ISBN : 9781839625039

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Novel Perspectives of Stem Cell Manufacturing and Therapies by Diana Kitala,Ana Colette Maurício Pdf

In the 1950s, Nobel Prize winner Dr. E. Donnall Thomas was the first to successfully transplant hematopoietic stem cells. Since then, studies on stem cells have evolved and expanded worldwide. There are more than 650,000 scientific publications on stem cells and more than 8000 stem cell clinical trials. This book summarizes types of stem cells, key studies, ongoing trials, and future perspectives. It also includes ethical, formal, and legal aspects to give the reader a comprehensive view of the field.

Author : Brenda M. Davis
Publisher : Nova Science Publishers
Page : 396 pages
File Size : 48,8 Mb
Release : 2011
Category : Stem cells
ISBN : 1620819937

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Perspectives in Stem Cell Research by Brenda M. Davis Pdf

Author : Henning Ulrich
Publisher : Springer Science & Business Media
Page : 290 pages
File Size : 51,8 Mb
Release : 2010-01-14
Category : Science
ISBN : 9789048133758

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Perspectives of Stem Cells by Henning Ulrich Pdf

Stem cells are fascinating cell types. They can replicate themselves forever while retaining the potential to generate progeny with speci?c functions. Because of these special properties, stem cells have been subjects of intensive investigation, from understanding basic mechanisms underlying tissue generation, to modeling human diseases, to application for cell replacement therapy. Stem cells come in different forms. For example, mouse embryonic stem cells can general all cell types in a body, either in a dish or when put back into mouse embryos. On the other hand, neural stem cells in the adult brain generate neurons and glia cells that contribute to the brain’s plasticity. Rapid progress has been made in the stem cell ?eld with discov- ies published in a record speed. A quick Pubmed search has returned 2789 hits for “embryonic stem cells” and 815 hits for “adult neural stem cells/neurogenesis” in the year 2008 alone. It remains a taunting task for all who are interested in stem cells to keep up with rapidly accumulating literatures. The “Perspectives of Stem Cells” by a truly international team of experts provides a timely and invaluable highlight of the stem cell ?eld gearing toward future therapeutic applications in the nervous system. Stem cells with neural potentials have attracted a lot of attention because of their promise for cell replacement therapy, ranging from degenerative neurological dis- ders to spinal cord injuries.

Author : Leonard A. Vettiducci
Publisher : Nova Publishers
Page : 200 pages
File Size : 49,7 Mb
Release : 2007
Category : Medical
ISBN : STANFORD:36105123231198

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Perspectives on Stem Cell Research by Leonard A. Vettiducci Pdf

Stem cells are primal undifferentiated cells that retain the ability to divide and differentiate into other cell types. In higher plants this function is the defining property of the meristematic cells. Stem cells have the ability to act as a repair system for the body, because they can divide and differentiate, replenishing other cells as long as the host organism is alive. Medical researchers believe stem cell research has the potential to change the face of human disease by being used to repair specific tissues or to grow organs. This book presents related research in this field.

Author : Robert Lanza,John Gearhart,Brigid Hogan,Douglas Melton,Roger Pedersen,E. Donnall Thomas,James A. Thomson,Ian Wilmut
Publisher : Academic Press
Page : 681 pages
File Size : 43,5 Mb
Release : 2009-06-05
Category : Science
ISBN : 9780080884974

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Essentials of Stem Cell Biology by Robert Lanza,John Gearhart,Brigid Hogan,Douglas Melton,Roger Pedersen,E. Donnall Thomas,James A. Thomson,Ian Wilmut Pdf

First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing the latest advances in stem cells. Representing the combined effort of seven editors and more than 200 scholars and scientists whose pioneering work has defined our understanding of stem cells, this book combines the prerequisites for a general understanding of adult and embryonic stem cells with a presentation by the world's experts of the latest research information about specific organ systems. From basic biology/mechanisms, early development, ectoderm, mesoderm, endoderm, methods to application of stem cells to specific human diseases, regulation and ethics, and patient perspectives, no topic in the field of stem cells is left uncovered. Selected for inclusion in Doody's Core Titles 2013, an essential collection development tool for health sciences libraries Contributions by Nobel Laureates and leading international investigators Includes two entirely new chapters devoted exclusively to induced pluripotent stem (iPS) cells written by the scientists who made the breakthrough Edited by a world-renowned author and researcher to present a complete story of stem cells in research, in application, and as the subject of political debate Presented in full color with glossary, highlighted terms, and bibliographic entries replacing references

Author : Christine Mummery,Anja van de Stolpe,Bernard Roelen,Hans Clevers
Publisher : Academic Press
Page : 448 pages
File Size : 48,6 Mb
Release : 2014-05-23
Category : Science
ISBN : 9780124115675

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Stem Cells by Christine Mummery,Anja van de Stolpe,Bernard Roelen,Hans Clevers Pdf

The second edition of Stem Cells: Scientific Facts and Fiction provides the non-stem cell expert with an understandable review of the history, current state of affairs, and facts and fiction of the promises of stem cells. Building on success of its award-winning preceding edition, the second edition features new chapters on embryonic and iPS cells and stem cells in veterinary science and medicine. It contains major revisions on cancer stem cells to include new culture models, additional interviews with leaders in progenitor cells, engineered eye tissue, and xeno organs from stem cells, as well as new information on "organs on chips" and adult progenitor cells. In the past decades our understanding of stem cell biology has increased tremendously. Many types of stem cells have been discovered in tissues that everyone presumed were unable to regenerate in adults, the heart and the brain in particular. There is vast interest in stem cells from biologists and clinicians who see the potential for regenerative medicine and future treatments for chronic diseases like Parkinson's, diabetes, and spinal cord lesions, based on the use of stem cells; and from entrepreneurs in biotechnology who expect new commercial applications ranging from drug discovery to transplantation therapies. Explains in straightforward, non-specialist language the basic biology of stem cells and their applications in modern medicine and future therapy Includes extensive coverage of adult and embryonic stem cells both historically and in contemporary practice Richly illustrated to assist in understanding how research is done and the current hurdles to clinical practice

Author : Benjamin J. Capps,Alastair V. Campbell
Publisher : World Scientific
Page : 517 pages
File Size : 41,5 Mb
Release : 2010
Category : Medical
ISBN : 9781848164376

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Contested Cells by Benjamin J. Capps,Alastair V. Campbell Pdf

This book represents the coming together of a number of internationally renowned scholars from science, philosophy, law and social science. Each author presents a distinctive and critical account of the current ethical, social and jurisprudential issues concerning stem cell science: together covering both its research beginnings, and the future translation into the clinical setting. Original to this volume is an emphasis on the inter-state implications of developments in stem cell science from the perspective of a truly global collaboration of leading authors. Academics and policy-makers will find it an invaluable contribution to the socio-political and ethical discourse of stem cell science. Contributions from a team of leading academic experts Covers a wide array of disciplines: with original contributions focusing on the technological, legal, social and ethical aspects of stem cell science A unique collection of international perspectives on developments in stem cell science Book jacket.

Author : Khawaja H. Haider
Publisher : Springer Nature
Page : 260 pages
File Size : 42,9 Mb
Release : 2021-11-30
Category : Science
ISBN : 9783030770525

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Stem Cells by Khawaja H. Haider Pdf

In this volume, the contributing authors from top labs involved in stem cell theranostics share the latest advances in the field of stem cell research. The book covers many aspects of stem cell-based therapy and the progress made toward stem cell therapy for liver, ocular, and cardiovascular diseases as well as cancer. This volume serves as a continuation of Prof. Khawaja Husnain Haider’s previously edited books pertaining to stem cells-based therapnostics. This is an ideal book for researchers involved in drug development as well as regenerative medicine and stem cell-based therapy. The secondary audience includes graduate and postgraduate medical students, doctors, cellular pharmacology, drug industry, and researchers involved in using stem cells as ex-vivo disease models for drug development.

Author : Aditya Bharadwaj
Publisher : Springer
Page : 243 pages
File Size : 50,8 Mb
Release : 2017-10-30
Category : Social Science
ISBN : 9783319637877

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Global Perspectives on Stem Cell Technologies by Aditya Bharadwaj Pdf

This book takes as its point of departure a humble cell lying on the intersection of ideas as diverse and yet interlaced as life, knowledge, commerce, governance, and ethics. It seeks to deepen the understanding of stem cell entities and the concerns, hopes, and aspirations that shape and make them viable therapeutic entities in the context of rapid globalization. Several key intersections between individual, group, and institutional relationships have become central to locating and debating the production of stem cells today. This edited collection addresses three overarching concerns: regenerating the notion of ethics, the emerging therapeutic horizons, and the position of the patient. As a whole this book seeks to explain how stem cells are accommodated, contested, and used in contemporary India and around the globe through an informed unpacking of issues underpinning contestation and promotion bestriding these technological developments. The authors offer a truly multi-disciplinary perspective, stimulating conversation between the social sciences, biological sciences and the patient. The concerns expressed and highlighted by these conversations are embedded in a vast geo-political expanse stretching from India to Euro-America and will be of great interest to academics and practitioners across fields including science technology studies, medicine and international development.

Author : Katiucia Batista Silva Paiva,Valerie Kouskoff,Atsushi Asakura
Publisher : Frontiers Media SA
Page : 171 pages
File Size : 45,8 Mb
Release : 2020-08-21
Category : Electronic
ISBN : 9782889635276

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Stem Cell Research – State of Art, Revised Concepts and Perspectives by Katiucia Batista Silva Paiva,Valerie Kouskoff,Atsushi Asakura Pdf

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Author : Paul Knoepfler
Publisher : World Scientific
Page : 368 pages
File Size : 50,5 Mb
Release : 2013
Category : Science
ISBN : 9789814508810

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Stem Cells by Paul Knoepfler Pdf

Stem Cells: An Insider's Guide is an exciting new book that takes readers inside the world of stem cells guided by international stem cell expert, Dr. Paul Knoepfler. Stem cells are catalyzing a revolution in medicine. The book also tackles the exciting and hotly debated area of stem cell treatments that are capturing the public's imagination. In the future they may also transform how we age and reproduce. However, there are serious risks and ethical challenges, too. The author's goal with this insider's guide is to give readers the information needed to distinguish between the ubiquitous hype and legitimate hope found throughout the stem cell world. The book answers the most common questions that people have about stem cells. Can stem cells help my family with a serious medical problem such as Alzheimer's, Multiple Sclerosis, or Autism Are such treatments safe Can stem cells make me look younger or even literally stay physically young These questions and many more are answered here. A number of ethical issues related to stem cells that spark debates are discussed, including risky treatments, cloning and embryonic stem cells. The author breaks new ground in a number of ways such as by suggesting reforms to the FDA, providing a new theory of aging based on stem cells, and including a revolutionary Stem Cell Patient Bill of Rights. More generally, the book is your guide to where the stem cell field will be in the near future as well as a thoughtful perspective on how stem cell therapies will ultimately change your life and our world.

Author : Adam C. Berger,Sarah H. Beachy,Board on Health Sciences Policy,Steve Olson,Board on Life Sciences,Division on Earth and Life Sciences,Institute of Medicine,National Academy of Sciences
Publisher : National Academy Press
Page : 108 pages
File Size : 40,9 Mb
Release : 2014-06-18
Category : Medical
ISBN : 0309303001

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Stem Cell Therapies by Adam C. Berger,Sarah H. Beachy,Board on Health Sciences Policy,Steve Olson,Board on Life Sciences,Division on Earth and Life Sciences,Institute of Medicine,National Academy of Sciences Pdf

Stem cells offer tremendous promise for advancing health and medicine. Whether being used to replace damaged cells and organs or else by supporting the body's intrinsic repair mechanisms, stem cells hold the potential to treat such debilitating conditions as Parkinson's disease, diabetes, and spinal cord injury. Clinical trials of stem cell treatments are under way in countries around the world, but the evidence base to support the medical use of stem cells remains limited. Despite this paucity of clinical evidence, consumer demand for treatments using stem cells has risen, driven in part by a lack of available treatment options for debilitating diseases as well as direct-to-consumer advertising and public portrayals of stem cell-based treatments. Clinics that offer stem cell therapies for a wide range of diseases and conditions have been established throughout the world, both in newly industrialized countries such as China, India, and Mexico and in developed countries such as the United States and various European nations. Though these therapies are often promoted as being established and effective, they generally have not received stringent regulatory oversight and have not been tested with rigorous trials designed to determine their safety and likely benefits. In the absence of substantiated claims, the potential for harm to patients - as well as to the field of stem cell research in general - may outweigh the potential benefits. To explore these issues, the Institute of Medicine, the National Academy of Sciences, and the International Society for Stem Cell Research held a workshop in November 2013. "Stem Cell Therapies" summarizes the workshop. Researchers, clinicians, patients, policy makers, and others from North America, Europe, and Asia met to examine the global pattern of treatments and products being offered, the range of patient experiences, and options to maximize the well-being of patients, either by protecting them from treatments that are dangerous or ineffective or by steering them toward treatments that are effective. This report discusses the current environment in which patients are receiving unregulated stem cell offerings, focusing on the treatments being offered and their risks and benefits. The report considers the evidence base for clinical application of stem cell technologies and ways to assure the quality of stem cell offerings.

Author : Benjamin J Capps,Alastair V Campbell
Publisher : World Scientific
Page : 516 pages
File Size : 51,5 Mb
Release : 2010-08-19
Category : Medical
ISBN : 9781908978295

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Contested Cells: Global Perspectives On The Stem Cell Debate by Benjamin J Capps,Alastair V Campbell Pdf

This book represents the coming together of a number of internationally renowned scholars from science, philosophy, law and social science. Each author presents a distinctive and critical account of the current ethical, social and jurisprudential issues concerning stem cell science: together covering both its research beginnings, and the future translation into the clinical setting. Original to this volume is an emphasis on the inter-state implications of developments in stem cell science from the perspective of a truly global collaboration of leading authors. Academics and policy-makers will find it an invaluable contribution to the socio-political and ethical discourse of stem cell science./a