Pet In The Evaluation Of Alzheimer S Disease And Related Disorders

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PET in the Evaluation of Alzheimer's Disease and Related Disorders

Dan Silverman
PET in the Evaluation of Alzheimer s Disease and Related Disorders Book PDF

Author : Dan Silverman
Publisher : Springer Science & Business Media
Page : 221 pages
File Size : 48,8 Mb
Release : 2011-04-14
Category : Medical
ISBN : 9780387764207

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PET in the Evaluation of Alzheimer's Disease and Related Disorders by Dan Silverman Pdf

Among all the clinical indications for which radiologists, nuclear medicine phy- cians, neurologists, neurosurgeons, psychiatrists (and others examining disorders of the brain) order and read brain PET scans, demand is greatest for those pertaining to dementia and related disorders. This demand is driven by the sheer prevalence of those conditions, coupled with the fact that the differential diagnosis for causes of cognitive impairment is wide and often difficult to distinguish clinically. The conceptual framework by which evaluation and management of dementia is guided has evolved considerably during the last decade. Although we still are far from having ideal tests or dramatic cures for any of the established causes of dementia, our options have expanded with respect to both the diagnostic and the- peutic tools now available. In the first chapter of this book, the contribution and limitations of different elements of the clinical examination for diagnosis of cog- tive symptoms are described, and the roles of structural and functional neuroim- ing in the clinical workup are given context.

PET in the Aging Brain, An Issue of PET Clinics

Andrew B. Newberg,Abass Alavi
PET in the Aging Brain An Issue of PET Clinics Book PDF

Author : Andrew B. Newberg,Abass Alavi
Publisher : Elsevier Health Sciences
Page : 141 pages
File Size : 54,7 Mb
Release : 2010-06-22
Category : Medical
ISBN : 9781455700554

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PET in the Aging Brain, An Issue of PET Clinics by Andrew B. Newberg,Abass Alavi Pdf

PET imaging has shown its value in diagnosing diseases affecting older people. Most significantly this has been with regard to the diagnosis of Alzheimer’s disease and other forms of dementia. Parkinson’s disease is another condition in which PET has proved valuable. This issue also included articles on the uses of PET for diagnosing cerebrovascular disease and for assessing neuroplasticity.

Alzheimer's Disease

Zaven S Khachaturian,Teresa S. Radebaugh
Alzheimer s Disease Book PDF

Author : Zaven S Khachaturian,Teresa S. Radebaugh
Publisher : CRC Press
Page : 579 pages
File Size : 54,5 Mb
Release : 2019-06-04
Category : Medical
ISBN : 9780429535970

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Alzheimer's Disease by Zaven S Khachaturian,Teresa S. Radebaugh Pdf

Published in 1996: Alzheimer's disease is characterized by memory disturbances and changes in personality and is associated with aging, although it can occur in people under 65. It is a progressive disease, painful to witness as the patient's health declines. Alzheimer's Disease: Cause(s), Diagnosis, and Care, with its complete and authoritative discussions, will help you understand all facets of this complex disease. This book addresses a broad spectrum of topics ranging from diagnosis, causes, treatment, epidemiology, genetics, risk factors, and care and management. Alzheimer's Disease: Cause(s), Diagnosis, and Care is intended for a diverse audience, including practitioners and students, family members, and everyone who is concerned about this disease.

Human and Animal Models for Translational Research on Neurodegeneration: Challenges and Opportunities From South America

Agustín Ibáñez,Lucas Sedeño,Adolfo M. García,Robert M.J. Deacon,Patricia Cogram
Human and Animal Models for Translational Research on Neurodegeneration Challenges and Opportunities From South America Book PDF

Author : Agustín Ibáñez,Lucas Sedeño,Adolfo M. García,Robert M.J. Deacon,Patricia Cogram
Publisher : Frontiers Media SA
Page : 217 pages
File Size : 53,7 Mb
Release : 2018-06-21
Category : Electronic
ISBN : 9782889454945

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Human and Animal Models for Translational Research on Neurodegeneration: Challenges and Opportunities From South America by Agustín Ibáñez,Lucas Sedeño,Adolfo M. García,Robert M.J. Deacon,Patricia Cogram Pdf

Neurodegenerative diseases are the most frequent cause of dementia, representing a burden for public health systems (especially in middle and middle-high income countries). Although most research on this issue is concentrated in first-world centers, growing efforts in South America are affording important breakthroughs. This emerging agenda poses new challenges for the region but also new opportunities for the field. This book aims to integrate the community of experts across the globe and the region, and to establish new challenges and developments for future investigation. We present research focused on neurodegenerative research in South America. We introduce studies assessing the interplay among genetic, neural, and behavioral dimensions of these diseases, as well as articles on vulnerability factors, comparisons of findings from various countries, and works promoting multicenter and collaborative networking. More generally, our book covers a broad scope of human-research approaches (behavioral assessment, neuroimaging, electromagnetic techniques, brain connectivity, peripheral measures), animal methodologies (genetics, epigenetics, proteomics, metabolomics, other molecular biology tools), species (all human and non-human animals, sporadic, and genetic versions), and article types (original research, review, and opinion papers). Through this wide-ranging proposal, we hope to introduce a fresh approach to the challenges and opportunities of research on neurodegeneration in South America.

PET and SPECT in Neurology

Rudi A. J. O. Dierckx,Andreas Otte,Erik F. J. de Vries,Aren van Waarde,Klaus L. Leenders
PET and SPECT in Neurology Book PDF

Author : Rudi A. J. O. Dierckx,Andreas Otte,Erik F. J. de Vries,Aren van Waarde,Klaus L. Leenders
Publisher : Springer Nature
Page : 1270 pages
File Size : 52,6 Mb
Release : 2020-10-20
Category : Medical
ISBN : 9783030531683

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PET and SPECT in Neurology by Rudi A. J. O. Dierckx,Andreas Otte,Erik F. J. de Vries,Aren van Waarde,Klaus L. Leenders Pdf

This book provides a comprehensive overview of the use of PET and SPECT in not only classic neurodegenerative disorders but also cerebrovascular disorders, brain tumors, epilepsy, head trauma, coma, sleeping disorders, and inflammatory and infectious diseases of the CNS. The new edition has been revised and updated to reflect recent advances and includes additional chapters, for example on the use of artificial intelligence and machine learning in imaging data analysis, the study of brain connectivity using PET and SPECT images, and the role of PET imaging in modulation of brain functioning by deep brain stimulation. The authors are renowned experts whose dedication to the investigation of neurological disorders through nuclear medicine technology has achieved international recognition. Most chapters are written jointly by a clinical neurologist and a nuclear medicine specialist to ensure a multidisciplinary approach. This state of the art compendium will be invaluable for neurologists and radiologists/nuclear medicine specialists and will also be informative for interested general practitioners and geriatricians. Companion volumes on PET and SPECT in psychiatry and in neurobiological systems complete a trilogy.

Late Onset Schizophrenia

Robert Howard,Peter V. Rabins,David J. Castle
Late Onset Schizophrenia Book PDF

Author : Robert Howard,Peter V. Rabins,David J. Castle
Publisher : Routledge
Page : 296 pages
File Size : 48,5 Mb
Release : 1999
Category : Medical
ISBN : UOM:39015047574929

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Late Onset Schizophrenia by Robert Howard,Peter V. Rabins,David J. Castle Pdf

Schizophrenia, which starts in middle age or late life, has been described as 'the darkest area of psychiatry.' It is certainly controversial, with much disagreement about cut-off ages, diagnostic criteria and nomenclature. The contributors to this unique and very important book represent views from Europe and North America as well as Australia, Japan, and Nepal; they come from backgrounds of clinical practice and research. The contributors and editors were motivated by common aims: to review current international knowledge about late onset schizophrenia, to debate issues of heterogenity, gender, brain maturation and aging, putative structural and functional cerebral substrates for psychosis, to reach consensus on diagnosis and terminology, and to future research directions. The resulting book is an unqualified success which as well as being invaluable in old age psychiatry, sheds light on all aspects of schizophrenia treatment and research.

Hybrid PET/MR Neuroimaging

Ana M. Franceschi,Dinko Franceschi
Hybrid PET MR Neuroimaging Book PDF

Author : Ana M. Franceschi,Dinko Franceschi
Publisher : Springer Nature
Page : 848 pages
File Size : 44,6 Mb
Release : 2021-11-30
Category : Medical
ISBN : 9783030823672

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Hybrid PET/MR Neuroimaging by Ana M. Franceschi,Dinko Franceschi Pdf

This book serves as a reference and comprehensive guide for PET/MR neuroimaging. The field of PET/MR is rapidly evolving, however, there is no standard resource summarizing the vast information and its potential applications. This book will guide neurological molecular imaging applications in both clinical practice and the research setting. Experts from multiple disciplines, including radiologists, researchers, and physicists, have collaborated to bring their knowledge and expertise together. Sections begin by covering general considerations, including public health and economic implications, the physics of PET/MR systems, an overview of hot lab and cyclotron, and radiotracers used in neurologic PET/MRI. There is then coverage of each major disease/systemic category, including dementia and neurodegenerative disease, epilepsy localization, brain tumors, inflammatory and infectious CNS disorders, head and neck imaging, as well as vascular hybrid imaging. Together, we have created a thorough, concise and up-to-date textbook in a unique, user-friendly format. This is an ideal guide for neuroradiologists, nuclear medicine specialists, medical physicists, clinical trainees and researchers.

PET/MR Imaging

Rajesh Gupta,Robert Matthews,Lev Bangiyev,Dinko Franceschi,Mark Schweitzer
PET MR Imaging Book PDF

Author : Rajesh Gupta,Robert Matthews,Lev Bangiyev,Dinko Franceschi,Mark Schweitzer
Publisher : Springer
Page : 351 pages
File Size : 42,9 Mb
Release : 2017-12-02
Category : Medical
ISBN : 9783319651064

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PET/MR Imaging by Rajesh Gupta,Robert Matthews,Lev Bangiyev,Dinko Franceschi,Mark Schweitzer Pdf

This book offers an overview of the clinical applications of PET/MR imaging through a case-based format. Hybrid PET/MRI provides functional and anatomical information via one setting offering superior imaging quality with lower radiation dose being administered to the patient. The cases in this book focus on the use of this technique in the diagnosis of oncologic, neurologic, cardiovascular, infectious and inflammatory, and pediatric diseases. Each case is presented with the patient history, protocols, interpretation of findings, and pearls and pitfalls accompanied by high quality PET/MR images. The major strength of this book is the discussion of both MRI and PET findings pertinent to each particular case. It expands the discussion of oncologic applications of this modality through a variety of cases that highlight staging, treatment response, and follow up. Illustrating a spectrum of PET/MRI clinical applications, PET/MR Imaging: A Case-Based Approach is a valuable resource for radiologists, nuclear medicine physicians, and residents.

Neurology in Clinical Practice

Walter George Bradley
Neurology in Clinical Practice Book PDF

Author : Walter George Bradley
Publisher : Unknown
Page : 1672 pages
File Size : 41,6 Mb
Release : 2004
Category : Medical
ISBN : 0750674695

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Neurology in Clinical Practice by Walter George Bradley Pdf

New edition, completely rewritten, with new chapters on endovascular surgery and mitochrondrial and ion channel disorders.

Evidence-based Positron Emission Tomography

Anonim
Evidence based Positron Emission Tomography Book PDF

Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 43,9 Mb
Release : 2020
Category : Electronic books
ISBN : 3030477029

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Evidence-based Positron Emission Tomography by Anonim Pdf

This open access book summarizes the findings of recent evidence-based articles (meta-analyses) on the use of positron emission tomography (PET) for various clinical indications. It is divided into five main sections, starting with an introduction to PET and meta-analysis. In turn, the second part addresses evidence-based PET in oncology, providing a broad overview of its use for different types of tumours. The remaining sections are focused on the use of PET in cardiology, in infectious and inflammatory diseases, and in neurology, respectively. Given its scope and the wealth of information it provides, the book will be an invaluable tool for clinicians with various specialties, as well as international scientific societies interested to the recent evidence-based data about PET.

PET-CT and PET-MRI in Neurology

Andrea Ciarmiello,Luigi Mansi
PET CT and PET MRI in Neurology Book PDF

Author : Andrea Ciarmiello,Luigi Mansi
Publisher : Springer
Page : 319 pages
File Size : 52,8 Mb
Release : 2016-05-26
Category : Medical
ISBN : 9783319316147

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PET-CT and PET-MRI in Neurology by Andrea Ciarmiello,Luigi Mansi Pdf

Using SWOT analysis, this book examines in detail the strengths and weaknesses of the hybrid modalities PET-CT and PET-MRI for imaging of the central nervous system, comparing their merits and evaluating their advantages over the stand-alone modalities. The aim is to employ a truly systematic approach in order to define the potential clinical benefit of these modalities and to identify shortcomings, opportunities, and threats. Clinical application of the modalities is explored in a range of conditions, including dementia and related disorders, movement disorders, psychiatric disorders, cerebrovascular disease, infection/inflammation, brain tumors, and pediatric neurologic disorders. In addition, the basics of hybrid imaging are addressed, covering physics, instrumentation, data analysis and quantitation, radiopharmaceuticals, and contrast media. PET-CT and PET-MRI in Neurology, written by experts from Europe and the United States, will be essential reading for imaging specialists and of value for neurologists, psychiatrists, neurosurgeons, and pediatricians.

SPECT Imaging of the Brain

R. Duncan
SPECT Imaging of the Brain Book PDF

Author : R. Duncan
Publisher : Springer Science & Business Media
Page : 202 pages
File Size : 49,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401153980

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SPECT Imaging of the Brain by R. Duncan Pdf

In the developed world, images of brain structure are available as an everyday diagnostic aid, and the characteristic appearances of most pathological conditions can be looked up in a textbook. Functional brain imaging is to this day less widely used, partly because most pressing diagnostic questions can be answered by refer ence to the patient's cerebral anatomy, partly for reasons of technical limitations of functional techniques. PET as a technique is sufficiently resource-demanding and complex to inhibit its use as an everyday diagnostic technique. SPECT lacked suitable tracers for many years, and early systems had poor spatial resolution. However, rotating gamma camera technology has advanced to the point where images of the brain of reasonable quality can be obtained at most large hospitals, and practical tracers, particularly of regional cerebral blood flow, are easily avail able. As research advances, clinical applications are emerging. A recent report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology! details a number of currently recognised clinical appli cations, some of which are dealt with in this book. Given this recognition, it is increasingly important that clinicians (particularly neuroclinicians, psychiatrists and specialists in cerebrovascular disease), nuclear medicine specialists and physicists acquire an idea of the major applications of the technique, and the research background on which these applications are based.

Neuroimaging in Dementia

Frederik Barkhof,Nick C. Fox,António J. Bastos-Leite,Philip Scheltens
Neuroimaging in Dementia Book PDF

Author : Frederik Barkhof,Nick C. Fox,António J. Bastos-Leite,Philip Scheltens
Publisher : Springer Science & Business Media
Page : 278 pages
File Size : 55,8 Mb
Release : 2011-02-11
Category : Medical
ISBN : 9783642008184

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Neuroimaging in Dementia by Frederik Barkhof,Nick C. Fox,António J. Bastos-Leite,Philip Scheltens Pdf

This up-to-date, superbly illustrated book is a practical guide to the effective use of neuroimaging in the patient with cognitive decline. It sets out the key clinical and imaging features of the various causes of dementia and directs the reader from clinical presentation to neuroimaging and on to an accurate diagnosis whenever possible. After an introductory chapter on the clinical background, the available "toolbox" of structural and functional neuroimaging techniques is reviewed in detail, including CT, MRI and advanced MR techniques, SPECT and PET, and image analysis methods. The imaging findings in normal ageing are then discussed, followed by a series of chapters that carefully present and analyze the key findings in patients with dementias. Throughout, a practical approach is adopted, geared specifically to the needs of clinicians (neurologists, radiologists, psychiatrists, geriatricians) working in the field of dementia, for whom this book will prove an invaluable resource.

Early Diagnosis of Alzheimer’s Disease

Leonard F. M. Scinto,Kirk R. Daffner
Early Diagnosis of Alzheimer s Disease Book PDF

Author : Leonard F. M. Scinto,Kirk R. Daffner
Publisher : Springer Science & Business Media
Page : 366 pages
File Size : 46,5 Mb
Release : 2000-02-09
Category : Medical
ISBN : 9781592590056

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Early Diagnosis of Alzheimer’s Disease by Leonard F. M. Scinto,Kirk R. Daffner Pdf

Drs. Leonard Scinto and Kirk Daffner provide a comprehensive survey of new diagnostic approaches to Alzheimer's disease. The authoritative contributors critically survey the most promising current research on early diagnostic markers for Alzheimer's disease, including the elucidation of changes in the brain revealed by structural and functional neuroimaging, as well as the characteristic patterns of cognitive decline that are documented by sensitive neuropsychological tests, various genetic markers, and biological assays. Early Diagnosis of Alzheimer's Disease illuminates the complex issues surrounding the search for early markers of this increasingly widespread disease. It will establish a new standard reference guide for all those working with Alzheimer's patients.

Animal Models of Dementia

Peter Paul De Deyn,Debby Van Dam
Animal Models of Dementia Book PDF

Author : Peter Paul De Deyn,Debby Van Dam
Publisher : Humana Press
Page : 732 pages
File Size : 41,7 Mb
Release : 2010-12-01
Category : Medical
ISBN : 1607618974

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Animal Models of Dementia by Peter Paul De Deyn,Debby Van Dam Pdf

With an ever-increasing elderly population and the resultant rising levels of dementia-related disorders, preclinical research based on animal models is pivotal to our knowledge of underlying molecular mechanisms and drug discovery aiming at the development of therapeutic strategies alleviating or preventing the neurological devastation. In Animal Models of Dementia, expert researchers provide contributions that stress the importance of extensively validated animal models in drug discovery and development in order to predict clinical activity. Beginning with general aspects of animal modeling, related ethical issues, and essential methodological considerations, the highly detailed volume then continues with various levels of model validation, including pathological, behavioral, neurochemical, pharmacological, and imaging aspects, followed by sections focused on specific disorders, such as Alzheimer’s disease, Parkinson’s disease, metachromatic leukodystrophy and adrenoleukodystrophy, amyotrophic lateral sclerosis, frontotemporal dementia as well as vascular dementia and more. As a volume in the renowned Neuromethods series, this book offers a detailed, yet accessible, overview of currently available animal models in the field of dementia research, and touches, as well, upon more general areas linked to the development and use of animal models. Comprehensive and efficient, Animal Models of Dementia will significantly aid both experienced animal researchers as well as investigators on the verge of beginning animal model-based dementia research.