Pharmacological Properties Of Plant Derived Natural Products And Implications For Human Health

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Pharmacological Properties of Plant-Derived Natural Products and Implications for Human Health

George E. Barreto,Amirhossein Sahebkar
Pharmacological Properties of Plant Derived Natural Products and Implications for Human Health Book PDF

Author : George E. Barreto,Amirhossein Sahebkar
Publisher : Springer Nature
Page : 603 pages
File Size : 41,6 Mb
Release : 2021-04-16
Category : Medical
ISBN : 9783030648725

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Pharmacological Properties of Plant-Derived Natural Products and Implications for Human Health by George E. Barreto,Amirhossein Sahebkar Pdf

Medicinal plants and their derived products remain as an indispensable source of bioactive molecules that serve as either drug candidates or lead compounds for drug design and discovery. There are several advantages for plant-derived therapeutics including wide availability, diverse pharmacological actions and a generally good profile of safety and tolerability. Over the recent years, there have been numerous reports from clinical studies testifying to the efficacy and safety of medicinal plants and phytochemicals in ameliorating several human diseases. A plethora of basic studies has also unravelled molecular mechanisms underlying the health benefits of herbal medicines. Nevertheless, issues such as identification of bioactive ingredients, standardization of the products and drug interactions remain to be further studied. In this book, we aim to put together several chapters on the medicinal properties and pharmacological action of medicinal plants, plant species and phytochemicals. The goal is to present a comprehensive collection on most of the therapeutic aspects of plant-derived natural products and molecular mechanisms thereof.

Medicinal Plants for Holistic Health and Well-Being

Namrita Lall
Medicinal Plants for Holistic Health and Well Being Book PDF

Author : Namrita Lall
Publisher : Academic Press
Page : 328 pages
File Size : 40,6 Mb
Release : 2017-09-27
Category : Medical
ISBN : 9780128124765

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Medicinal Plants for Holistic Health and Well-Being by Namrita Lall Pdf

Medicinal Plants for Holistic Health and Well-Being discusses, in depth, the use of South African plants to treat a variety of ailments, including tuberculosis, cancer, periodontal diseases, acne, postmacular hypomelanosis, and more. Plants were selected on the basis of their traditional use, and the book details the scientific evidence that supports their pharmacological and therapeutic potential to safely and effectively treat each disease. Thus, this book is a valuable resource for all researchers, students and professors involved in advancing global medicinal plant research. Many plants found in South Africa are also found in other parts of the world. Each chapter highlights plants from other worldwide locations so that scientists can study which plants belong to the same family, and how similar qualities can be used to treat a specific disease. Uses traditional medicine as an efficient means to identify and further investigate South African and similar plants used as lead compounds in modern drug discovery Includes a number of chapters dedicated to using medicinal plants to treat various skin disorders, which is not covered often in other books on medicinal plants Organized by specific diseases, with vital evidence-based data related to the bioactivity, pharmacological potential, chemical structure and safety information

Plant-derived Natural Products

Anne E. Osbourn,Virginia Lanzotti
Plant derived Natural Products Book PDF

Author : Anne E. Osbourn,Virginia Lanzotti
Publisher : Springer Science & Business Media
Page : 588 pages
File Size : 46,9 Mb
Release : 2009-07-07
Category : Science
ISBN : 9780387854984

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Plant-derived Natural Products by Anne E. Osbourn,Virginia Lanzotti Pdf

Plants produce a huge array of natural products (secondary metabolites). These compounds have important ecological functions, providing protection against attack by herbivores and microbes and serving as attractants for pollinators and seed-dispersing agents. They may also contribute to competition and invasiveness by suppressing the growth of neighboring plant species (a phenomenon known as allelopathy). Humans exploit natural products as sources of drugs, flavoring agents, fragrances and for a wide range of other applications. Rapid progress has been made in recent years in understanding natural product synthesis, regulation and function and the evolution of metabolic diversity. It is timely to bring this information together with contemporary advances in chemistry, plant biology, ecology, agronomy and human health to provide a comprehensive guide to plant-derived natural products. Plant-derived natural products: synthesis, function and application provides an informative and accessible overview of the different facets of the field, ranging from an introduction to the different classes of natural products through developments in natural product chemistry and biology to ecological interactions and the significance of plant-derived natural products for humans. In the final section of the book a series of chapters on new trends covers metabolic engineering, genome-wide approaches, the metabolic consequences of genetic modification, developments in traditional medicines and nutraceuticals, natural products as leads for drug discovery and novel non-food crops.

Plant Natural Products for Human Health

Chun-Tao Che,Hongjie Zhang
Plant Natural Products for Human Health Book PDF

Author : Chun-Tao Che,Hongjie Zhang
Publisher : MDPI
Page : 514 pages
File Size : 46,5 Mb
Release : 2019-03-21
Category : Social Science
ISBN : 9783038977124

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Plant Natural Products for Human Health by Chun-Tao Che,Hongjie Zhang Pdf

Plants have served mankind as an important source of foods and medicines. While we all consume plants and their products for nutritional support, a majority of the world population also rely on botanical remedies to meet their health needs, either as their own “traditional medicine” or as “complementary and alternative medicine”. From a pharmaceutical point of view, many compounds obtained from plant sources have long been known to possess bio/pharmacological activities, and historically, plants have yielded many important drugs for human use, from morphine discovered in the early nineteenth century to the more recent paclitaxel and artemisinin. Today, we are witnessing a global resurgence in interest and use of plant-based therapies and botanical products, and natural products remain an important and viable source of lead compounds in many drug discovery programs. This Special Issue on “Plant Natural Products for Human Health” compiles a series of scientific reports to demonstrate the medicinal potentials of plant natural products. It covers a range of disease targets, such as diabetes, inflammation, cancer, neurological disease, cardiovascular disease, liver damage, bacterial, and fungus infection and malarial. These papers provide important insights into the current state of research on drug discovery and new techniques. It is hoped that this Special Issue will serve as a timely reference for researchers and scholars who are interested in the discovery of potentially useful molecules from plant sources for health-related applications.

Plant and Human Health, Volume 1

Munir Ozturk,Khalid Rehman Hakeem
Plant and Human Health Volume 1 Book PDF

Author : Munir Ozturk,Khalid Rehman Hakeem
Publisher : Springer
Page : 805 pages
File Size : 48,6 Mb
Release : 2018-10-02
Category : Science
ISBN : 9783319939971

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Plant and Human Health, Volume 1 by Munir Ozturk,Khalid Rehman Hakeem Pdf

Early anthropological evidence for plant use as medicine is 60,000 years old as reported from the Neanderthal grave in Iraq. The importance of plants as medicine is further supported by archeological evidence from Asia and the Middle East. Today, around 1.4 billion people in South Asia alone have no access to modern health care, and rely instead on traditional medicine to alleviate various symptoms. On a global basis, approximately 50 to 80 thousand plant species are used either natively or as pharmaceutical derivatives for life-threatening conditions that include diabetes, hypertension and cancers. As the demand for plant-based medicine rises, there is an unmet need to investigate the quality, safety and efficacy of these herbals by the “scientific methods”. Current research on drug discovery from medicinal plants involves a multifaceted approach combining botanical, phytochemical, analytical, and molecular techniques. For instance, high throughput robotic screens have been developed by industry; it is now possible to carry out 50,000 tests per day in the search for compounds, which act on a key enzyme or a subset of receptors. This and other bioassays thus offer hope that one may eventually identify compounds for treating a variety of diseases or conditions. However, drug development from natural products is not without its problems. Frequent challenges encountered include the procurement of raw materials, the selection and implementation of appropriate high-throughput bioassays, and the scaling-up of preparative procedures. Research scientists should therefore arm themselves with the right tools and knowledge in order to harness the vast potentials of plant-based therapeutics. The main objective of Plant and Human Health is to serve as a comprehensive guide for this endeavor. Volume 1 highlights how humans from specific areas or cultures use indigenous plants. Despite technological developments, herbal drugs still occupy a preferential place in a majority of the population in the third world and have slowly taken roots as alternative medicine in the West. The integration of modern science with traditional uses of herbal drugs is important for our understanding of this ethnobotanical relationship. Volume 2 deals with the phytochemical and molecular characterization of herbal medicine. Specifically, it focuess on the secondary metabolic compounds, which afford protection against diseases. Lastly, Volume 3 discusses the physiological mechanisms by which the active ingredients of medicinal plants serve to improve human health. Together this three-volume collection intends to bridge the gap for herbalists, traditional and modern medical practitioners, and students and researchers in botany and horticulture.

Herbal Biomolecules in Healthcare Applications

Subhash C. Mandal,Amit Kumar Nayak,Amal Kumar Dhara
Herbal Biomolecules in Healthcare Applications Book PDF

Author : Subhash C. Mandal,Amit Kumar Nayak,Amal Kumar Dhara
Publisher : Academic Press
Page : 752 pages
File Size : 53,8 Mb
Release : 2021-10-05
Category : Medical
ISBN : 9780323900805

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Herbal Biomolecules in Healthcare Applications by Subhash C. Mandal,Amit Kumar Nayak,Amal Kumar Dhara Pdf

Herbal Biomolecules in Healthcare Applications presents extensive detailed information on all the vital principles, basics and fundamental aspects of multiple herbal biomolecules in the healthcare industry. This book examines important herbal biomolecules including alkaloids, glycosides, flavonoids, anthraquinones, steroids, polysaccharides, tannins and polyphenolic compounds, terpenes, fats and waxes, proteins and peptides, and vitamins. These herbal biomacromolecules are responsible for different bioactivities as well as pharmacological potentials. A systematic understanding of the extraction, purification, characterization, applications of these herbal biomolecules and their derivatives in healthcare fields is developed in this comprehensive book. Chapters explore the key topics along with an emphasis on recent research and developments in healthcare fields by leading experts. They include updated literature review of the relevant key topics, good quality illustrations, chemical structures, flow charts, well-organized tables and case studies. Herbal Biomolecules in Healthcare Applications will be useful for researchers working on natural products and biomolecules with bioactivity and nutraceutical properties. Professionals specializing in scientific areas such as biochemistry, pharmacology, analytical chemistry, organic chemistry, clinics, or engineering focused on bioactive natural products will find this book useful. Provides a study of different type of biomolecules from herbal extracts and their bioactivities as well as their application in the healthcare industry Contributions by global leaders and experts from academia, industry and regulatory agencies, who have been considered as pioneers in the application of herbal biomolecules in the diverse healthcare fields Includes updated literature review along with practical examples and research case studies

Phytomedicine

Rouf Ahmad Bhat,Khalid Rehman Hakeem,Moonisa Aslam Dervash
Phytomedicine Book PDF

Author : Rouf Ahmad Bhat,Khalid Rehman Hakeem,Moonisa Aslam Dervash
Publisher : Academic Press
Page : 776 pages
File Size : 55,9 Mb
Release : 2021-02-20
Category : Science
ISBN : 9780128241103

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Phytomedicine by Rouf Ahmad Bhat,Khalid Rehman Hakeem,Moonisa Aslam Dervash Pdf

Phytomedicine: A Treasure of Pharmacologically Active Products from Plants aims to present updated knowledge of plant-based medicines in terms of their research and development, production, and utilization, from the viewpoint of sustainability and by using the latest technologies. The book explores different phytometabolites on a mass scale, coupled with the efficacy, performance and applicability on target organisms to treat curable and fatal diseases. Readers will find a coherent package of phytotherapeutic information regarding inclusive assortment of research based, scientific amplitude of metabolites from the plant world encompassing various action plans. Information is presented sequentially regarding phytochemistry, biological activity and the serviceable aspects of bioactive compounds. The book also addresses various advancements and achievements of novel drugs from plants using molecular and enzymatic activities, and various technological tools in an ecofriendly fashion. Discusses phytotherapeutic properties for a wide range of medical conditions, including anti-pyretic, anti-infective, anti-malarial, Anti-AIDS, anti-diabetic, anti-cancerous, immune-modulatory applications Includes a discussion of synergistic effects of formulations and antagonistic drug interactions Addresses advancements and achievements of novel plant-based drugs using molecular, enzymatic activities and various technological tools in an eco-friendly fashion

Phytochemicals

Venketeshwer Rao,Leticia Rao
Phytochemicals Book PDF

Author : Venketeshwer Rao,Leticia Rao
Publisher : BoD – Books on Demand
Page : 351 pages
File Size : 42,5 Mb
Release : 2015-09-30
Category : Science
ISBN : 9789535121701

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Phytochemicals by Venketeshwer Rao,Leticia Rao Pdf

Global dietary recommendations emphasize the consumption of plant-based foods for the prevention and management of chronic diseases. Plants contain many biologically active compounds referred to as phytochemicals or functional ingredients. These compounds play an important role in human health. Prior to establishing the safety and health benefits of these compounds, they must first be isolated, purified, and their physico-chemical properties established. Once identified, their mechanisms of actions are studied. The chapters are arranged in the order from isolation, purification and identification to in vivo and clinical studies, there by covering not only the analytical procedures used but also their nutraceutical and therapeutic properties.

Synthesis of Medicinal Agents from Plants

Ashish Tewari,Supriya Tiwari
Synthesis of Medicinal Agents from Plants Book PDF

Author : Ashish Tewari,Supriya Tiwari
Publisher : Elsevier
Page : 368 pages
File Size : 53,8 Mb
Release : 2018-04-17
Category : Science
ISBN : 9780081022740

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Synthesis of Medicinal Agents from Plants by Ashish Tewari,Supriya Tiwari Pdf

Synthesis of Medicinal Agents from Plants highlights the importance of synthesizing medicinal agents from plants and outlines methods for performing it effectively. Beginning with an introduction to the significance of medicinal plants, the book goes on to provide a historical overview of drug synthesis before exploring how this can be used to successfully replicate and adapt the active agents from natural sources. Chapters then explore the medicinal properties of a number of important plants, before concluding with a discussion of the future of drugs from medicinal plants. Illustrated with real-world examples, it is a practical resource for researchers in this field. In an age of rapid environmental destruction, hundreds of medicinal plants are at risk of extinction from overexploitation and deforestation, limiting the natural resources available for active agent extraction, thereby threatening the discovery of future cures for diseases. Simultaneously, with the increasing population and advances in medical sciences, the demand for drugs is continuously increasing and cannot be met with just plants. The ability to synthetically replicate the active compounds from these plants is essential in creating an ecologically-aware, sustainable future for drug design Includes detailed coverage of therapeutic compound synthesis Uses multiple real-world examples to support content Lays out a sustainable template for the future of developing active agents from natural products

Advanced Pharmacological Uses of Medicinal Plants and Natural Products

Singh, Ajeet,Singh, Padam,Bithel, Navneet
Advanced Pharmacological Uses of Medicinal Plants and Natural Products Book PDF

Author : Singh, Ajeet,Singh, Padam,Bithel, Navneet
Publisher : IGI Global
Page : 442 pages
File Size : 50,7 Mb
Release : 2020-02-21
Category : Medical
ISBN : 9781799820956

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Advanced Pharmacological Uses of Medicinal Plants and Natural Products by Singh, Ajeet,Singh, Padam,Bithel, Navneet Pdf

A vast majority of the world’s population lacks access to essential medicines and the provision of safe healthcare services. Medicinal plants and herbal medicines can be applied for pharmacognosy, or the discovery of new drugs, or as an aid for plant physiology studies. In recent years, there has been increased interest in the search for new chemical entities and the expression of resistance of many drugs available in the market has led to a shift in paradigm towards medicinal research. Herbal treatments, the most popular form of folk medicine, may become an important way of increasing access to healthcare services. Advanced Pharmacological Uses of Medicinal Plants and Natural Products provides emerging research exploring the theoretical and practical aspects of drug discovery from natural sources that allow for the effective treatment of human health problems without any side effects, toxicity, or drug resistance. Featuring coverage on a broad range of topics such as ethnobotany, therapeutic applications, and bioactive compounds, this book is ideally designed for pharmacologists, scientists, ethnobotanists, botanists, health researchers, professors, industry professionals, and health students in fields that include pharmaceutical drug development and discovery.

Natural Products from Plants, Second Edition

Leland J. Cseke,Ara Kirakosyan,Peter B. Kaufman,Sara Warber,James A. Duke,Harry L. Brielmann
Natural Products from Plants Second Edition Book PDF

Author : Leland J. Cseke,Ara Kirakosyan,Peter B. Kaufman,Sara Warber,James A. Duke,Harry L. Brielmann
Publisher : CRC Press
Page : 632 pages
File Size : 44,9 Mb
Release : 2006-06-23
Category : Science
ISBN : 0849329760

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Natural Products from Plants, Second Edition by Leland J. Cseke,Ara Kirakosyan,Peter B. Kaufman,Sara Warber,James A. Duke,Harry L. Brielmann Pdf

2008 NOMINEE The Council on Botanical and Horticultural Libraries Annual Award for a Significant Work in Botanical or Horticultural Literature From medicinal, industrial, and culinary uses to cutting-edge laboratory techniques in modern research and plant conservation strategies, Natural Products from Plants, Second Edition reveals a vastly expanded understanding of the natural products that plants produce. In a single volume, this bookoffers a thorough inventory of the various types of plant-derived compounds. It covers their chemical composition, structure, and properties alongside the most effective ways to identify, extract, analyze, and characterize new plant-derived compounds. The authors examine new information on the chemical mechanisms plants use to deter predators and pathogens, attract symbiotic organisms, and defend themselves against environmental stress—insights which are key for adapting such mechanisms to human health. Along with updated and revised information from the highly acclaimed first edition, the second edition presents seven new chapters and features more than 50% new material relating to plant constituents, natural product biochemistry, and molecular biology. The book incorporates in-depth treatment of natural product biosynthesis with new collection and extraction protocols, advanced separation and analytical techniques, up-to-date bioassays, as well as modern molecular biology and plant biotechnology for the production of natural products. Unique in its breadth and coverage, Natural Products from Plants, Second Edition belongs on the shelf of interested researchers, policymakers, and consumers— particularly those involved in disease prevention, treatment, and pharmaceutical applications—who need a complete guide to the properties, uses, and study of plant natural products.

Pharmacological Assays of Plant-Based Natural Products

Thangaraj Parimelazhagan
Pharmacological Assays of Plant Based Natural Products Book PDF

Author : Thangaraj Parimelazhagan
Publisher : Springer
Page : 188 pages
File Size : 53,7 Mb
Release : 2015-12-29
Category : Medical
ISBN : 9783319268118

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Pharmacological Assays of Plant-Based Natural Products by Thangaraj Parimelazhagan Pdf

This volume provides information on how to select and screen plants for their medicinal properties. It describes phytopharmacological techniques for extracting and qualitatively and quantitatively analyzing a plant’s phytochemicals. After a detailed in vitro investigation including nutritional and anti-nutritional analyses, medicinal properties were tested with various in vivo models for anti-inflammatory, analgesic, anti-pyretic, anticancer and anti-diabetic properties, as well as wound healing, neurodegenerative diseases, etc. Compound identification and purification techniques include, among others, TLC and column chromatography, as well as molecular docking with specific proteins.

Medicinal Plants

Mozaniel Santana De Oliveira,Eloisa Helena De Aguiar Andrade,Ravendra Kumar,Suraj Mali
Medicinal Plants Book PDF

Author : Mozaniel Santana De Oliveira,Eloisa Helena De Aguiar Andrade,Ravendra Kumar,Suraj Mali
Publisher : BoD – Books on Demand
Page : 456 pages
File Size : 47,6 Mb
Release : 2024-02-14
Category : Medical
ISBN : 9781803567433

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Medicinal Plants by Mozaniel Santana De Oliveira,Eloisa Helena De Aguiar Andrade,Ravendra Kumar,Suraj Mali Pdf

Medicinal Plants - Chemical, Biochemical, and Pharmacological Approaches presents an in-depth exploration of the multifaceted relationships between medicinal plants and human health. This comprehensive volume delves into the intricate chemical and biochemical aspects of plants, shedding light on their pharmacological properties and applications. Within this book, readers will find a detailed examination of plant-derived compounds, including alkaloids, flavonoids, essential oils, terpenes, and other bioactive constituents. These compounds are analyzed for their chemical structures and mechanisms of action, providing a foundational understanding of the chemical basis for their therapeutic potential. The book further elucidates the pharmacological actions of medicinal plants, showcasing their role in traditional healing practices as well as their integration into modern health care. It explores the diverse array of health conditions that can be addressed through phytotherapy, emphasizing evidence-based approaches that bridge the gap between traditional wisdom and contemporary scientific knowledge. Readers will gain insights into the latest research and discoveries in the field of phytochemistry, pharmacology, and ethnobotany, obtaining a comprehensive view of the potential applications of medicinal plants for various health-related purposes. The text also highlights the importance of sustainability and ethical practices in the harvesting and utilization of these botanical resources. Medicinal Plants - Chemical, Biochemical, and Pharmacological Approaches serves as an invaluable resource for scientists, healthcare professionals, and herbal enthusiasts alike, equipping them with a deep understanding of the chemical, biochemical, and pharmacological dimensions of these natural remedies. By promoting an evidence-based and sustainable approach to the use of medicinal plants, this book fosters a profound connection between the scientific community and the wealth of nature’s therapeutic offerings.

Plant-derived Bioactives

Mallappa Kumara Swamy
Plant derived Bioactives Book PDF

Author : Mallappa Kumara Swamy
Publisher : Springer Nature
Page : 619 pages
File Size : 48,8 Mb
Release : 2020-05-11
Category : Science
ISBN : 9789811517617

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Plant-derived Bioactives by Mallappa Kumara Swamy Pdf

Plants produce a vast number of bioactive compounds with different chemical scaffolds, which modulate a diverse range of molecular targets and are used as drugs for treating numerous diseases. Most present-day medicines are derived either from plant compounds or their derivatives, and plant compounds continue to offer limitless reserves for the discovery of new medicines. While different classes of plant compounds, like phenolics, flavonoids, saponins and alkaloids, and their potential pharmacological applications are currently being explored, their curative mechanisms are yet to be understood in detail. This book is divided into 2 volumes and offers detailed information on plant-derived bioactive compounds, including recent research findings. Volume 1, Plant-derived Bioactives: Chemistry and Mode of Action, discusses the chemistry of highly valued plant bioactive compounds and their mode of actions at the molecular level. Volume 2, Plant-derived Bioactives: Production, Properties and Therapeutic Applications, explores the sources, biosynthesis, production, biological properties and therapeutic applications of plant bioactives. Given their scope, these books are valuable resources for members of the scientific community wishing to further explore various medicinal plants and the therapeutic applications of their bioactive compounds. They appeal to scholars, teachers and scientists involved in plant product research, and facilitate the development of innovative new drugs.

Herbal Medicine

Iris F. F. Benzie,Sissi Wachtel-Galor
Herbal Medicine Book PDF

Author : Iris F. F. Benzie,Sissi Wachtel-Galor
Publisher : CRC Press
Page : 500 pages
File Size : 49,5 Mb
Release : 2011-03-28
Category : Health & Fitness
ISBN : 9781439807163

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Herbal Medicine by Iris F. F. Benzie,Sissi Wachtel-Galor Pdf

The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef