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Pharmacology in Clinical Neurosciences by Hemanshu Prabhakar,Charu Mahajan,Indu Kapoor Pdf
The pharmacodynamics and pharmacokinetics of several drugs is expected to be known to clinicians and researchers at all times. With advances in sciences and development of newer drugs very frequently, it is very important to keep your knowledge updated at all times. This title is a quick guide to researchers and clinicians for a quick reference. The title is also a vital resource for all streams of neurosciences (neuroanesthesia and neurointensive care) and is much different from a conventional pharmacology titles, being more reader friendly and to the point facilitated with numerous flowcharts and algorithms with each chapter being prepared in a standard structured manner.
Neurological Clinical Pharmacology by M. Eadie,J.H. Tyrer Pdf
In recent years there has been much interest in clinical pharmacology and its ap plication to the treatment of disease, including disease of the nervous system. At the same time there have been major advances in basic neuropharmacology. The aim of this book is to integrate clinical pharmacology with basic neuropharmacology and clinical neurology. The book discusses, in the light of clinical pharmacology, and par ticularly pharmacokinetics, the treatment of those disorders of the nervous system that are conventionally managed by the clinical neurologist. Matters pertaining to psychopharmacology have been deliberately excluded except in so far as they impinge on ordinary clinical neurological practice. The extent to which various disorders have been considered has depended partly on their importance to the clinical neurologist practising in non-tropical areas, and partly on the amount of data available relating to the relevant drug treatment. Thus the book is directed at clinical neurologists and those intending to practise clinical neurology. However it also contains material of in terest to the general physician, paediatrician, psychiatrist and clinical pharmacologist. Although the emphasis in this book is on drug treatment, to preserve balance it has seemed desirable to discuss briefly certain non-pharmacological aspects of thera peutics. The orderly methodical approach used in the book offers two possible advan tages: first, once the reader is familiar with the approach (see Guide to the Use of This Book, p.
Drugs in Neurology by Sathiji Nageshwaran,Heather Wilson,David Ledingham,Anthony Dickenson Pdf
Part of the Drugs in series, this book provides an easily accessible pocket-sized guide to the use of medications when treating patients with neurological ailments. Drugs in Neurology covers the breadth of medications used in modern neurology, including each drug's indications, contra-indications, side-effects and important interactions. The underlying pharmacology also feature (where known). Practical aspects related to prescribing and therapeutic drug monitoring are covered and based on the most up-to-date evidence-based guidance. Each drug monograph contains a small section drawing on the wisdom of the senior contributors of each chapter with regards to using the medication.
Author : Eric J. Nestler,Steven E. Hyman,Robert C. Malenka Publisher : McGraw Hill Professional Page : 514 pages File Size : 52,9 Mb Release : 2008-10-12 Category : Medical ISBN : 9780071641197
Molecular Neuropharmacology by Eric J. Nestler,Steven E. Hyman,Robert C. Malenka Pdf
Market: Pharmacy and medical students; neuroscientists; neurologists; pharmacologists Updated edition has an attractive full-color design with more illustrations Includes numerous Fact Boxes to help reinforce learning
Good Research Practice in Non-Clinical Pharmacology and Biomedicine by Anton Bespalov,Martin C. Michel,Thomas Steckler Pdf
This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.
Author : Gert J. Ter Horst,Jakob Korf Publisher : Springer Science & Business Media Page : 309 pages File Size : 42,7 Mb Release : 1996-11-01 Category : Medical ISBN : 9781592594726
Clinical Pharmacology of Cerebral Ischemia by Gert J. Ter Horst,Jakob Korf Pdf
A distinguished international panel of authors define our current understanding of neuronal damage after ischemia and critically review the significant recent developments and progress in cerebrovascular accident (CVA) drug trials, both in animal models and in the clinical setting. These leading basic and fundamental authorities survey such important new drugs as calcium-influx inhibitors, free-radical scavenging drugs, glutamate and glycinergic antagonists, and immune suppressors. They also evaluate all the latest findings concerning calcium homeostasis, glutamate toxicity, gene activation, and the role of free radicals, glycine, and hormones. Chapters devoted to the neuroimaging of stroke, clinical trials, and the role of cerebral immune activation complete this informative collection of cutting-edge reviews.
Neuroimmune Pharmacology by Tsuneya Ikezu,Howard E. Gendelman Pdf
Neuroimmune pharmacology seeks to harness the immune system to provide pharmacological intervention to combat neurodegenerative diseases. This book provides a comprehensive overview of topics that embrace the link between the immune system and the pathogenesis of neurodegenerative disorders. Results from recent studies strongly suggest that a major part of the process in diseases including Alzheimer’s and Parkinson’s as well as Prion diseases, comes from changes in the innate and adaptive arms of the brain and peripheral immune systems. Thus, the book provides an in-depth study of numerous fields including immunology, pharmacology, neuroscience and neurovirology. It is accompanied by a CD-ROM that includes access to lectures, slide presentations, and question and answers on neuroimmune pharmacology.
Stimulant Drugs and ADHD by Mary V. Solanto,Amy Frances Torrance Arnsten,F. Xavier Castellanos Pdf
Stimulant drugs are widely used in the treatment of ADHD in children and adults. Hundreds of studies over the past 60 years have demonstrated their effectiveness in improving attention span, increasing impulse control, and reducing hyperactivity and restlessness. Despite widespread interest in these compounds, however, their mechanisms of action in the central nervous system have remained poorly understood. Recent advances in the basic and clinical neurosciences now afford the possibility of elucidating these mechanisms. The current volume is the first to bring this expanding knowledge to bear on the central question of why and how stimulants exert their therapeutic effects. The result is a careful, comprehensive, and insightful integration of material by well-known scientists that significantly advances our understanding of stimulant effects and charts a course for future research. Part I presents a comprehensive description of the clinical features of ADHD and the clinical response to stimulants. Part II details the cortical and subcortical neuroanatomy and functional neurophysiology of dopamine and norepinephrine systems with respect to the regulation of attention, arousal, activity, and impulse control and the effects of stimulants on these systems. Part III is devoted to clinical research, including recent studies of neuroimaging, genetics, pharmacodynamic and pharmacokinetic properties of stimulants, effects on cognitive functions, neurophysiological effects in humans with and without ADHD and in non-human primates, and comparison of stimulants and non-stimulants in the treatment of ADHD. Part IV is a masterful synthesis that presents alternative models of stimulant drug action and generates key hypotheses for continued research. The volume will be of keen interest to researchers and clinicians in psychiatry, psychology, and neurology, neuroscientists studying stimulants, and those pursuing development of new drugs to treat ADHD.
Author : Eric J. Nestler,Steven E. Hyman,Robert C. Malenka Publisher : McGraw Hill Professional Page : 543 pages File Size : 44,6 Mb Release : 2015-03-22 Category : Medical ISBN : 9780071827706
Molecular Neuropharmacology: A Foundation for Clinical Neuroscience, Third Edition by Eric J. Nestler,Steven E. Hyman,Robert C. Malenka Pdf
GAIN A COMPLETE UNDERSTANDING OF NERVOUS SYSTEM FUNCTION AND ITS RELATIONSHIP TO HUMAN NEUROLOGIC DISORDERS Molecular Neuropharmacology first reviews the fundamental biochemistry of the functioning nervous system and then describes how nerve cells communicate with one another through numerous types of neurotransmitters involving amino acids, monoamines, neuropeptides, and neurotrophic factors, among several others. The neuropharmacology and neural circuits that underlie complex behaviors as well as major neural disorders are also discussed as are the drugs used to treat those conditions. In the final section, the authors use the concepts presented in the first two sections to explainhow irregularities in the biochemistry of neuronal interactions can lead to a wide array of clinical manifestations. FEATURES NEW chapter on neuroinflammation All chemical structure illustrations have been redrawn and improved Fully updated to reflect the latest breakthroughs and new drugs The most well-written and easily understood work on the subject More than 300 full-color illustrations!
From Neuron to Action by Lüder Deecke,John Eccles,Vernon B. Mountcastle Pdf
A rich source of information about human voluntary movement in health and disease can be found in this book. The most esteemed researchers in their respective fields bring you up-to-date articles. Their collected work combines fundamental research in the life sciences with clinical neuroscience in a unique overview. The interdisciplinary aspects of motor physiology uncover a wealth of information for researchers from neighboring disciplines. For example, oculomotor research, vestibular research, equilibrium, sensory research and cognition, evolution, synaptic and elementary processes and the neurological sciences can be discovered.
Neuropsychopharmacology and Therapeutics by Ivor Ebenezer Pdf
Neuropsychopharmacology is a relatively new subject area in the neurosciences. It is a field of study that describes the effects of drugs from the molecular to the behavioural level and requires integration and synthesis of knowledge from various disciplines including neuroanatomy, physiology, molecular biology, pharmacology and the behavioural sciences. The principal aims of this book are to provide students with a clear understanding of CNS disorders, and an appreciation of how basic and clinical research findings can be translated into therapeutics. After an introduction to the subject area, the remaining chapters are focused on reviewing the main psychiatric and neurological disorders that are covered in most courses. They are discussed in terms of their clinical symptoms, epidemiology, pathology, aetiology, underlying neurobiological and neurochemical mechanisms, pharmacotherapy, adjunctive non-pharmacological treatments, and clinical outcomes. Each chapter of the book is a ‘stand-alone’ chapter and is written in a clear, accessible style. Written by an author with many years teaching and research experience, this textbook will prove invaluable for students of pharmacology, pharmacy and the medical sciences needing a truly integrated introduction to this exciting field.
Translational Neuropsychopharmacology by Trevor W. Robbins,Barbara J. Sahakian Pdf
This book covers wide areas of animal and human psychopharmacology with clinical utility in the treatment of psychiatric and neurological (e.g Alzheimer's disease) disorders. The main theme is to develop a new paradigm for drug discovery that questions the claim that animal models or assays fail adequately to predict Phase 3 clinical trials. A new paradigm is advocated that stresses the importance of intermediate staging points between these extremes that depend on suitable translation of findings from animal studies to Phase 1 or Phase 2 studies utilising experimental medicine.
Placebo by Fabrizio Benedetti,Paul Enck,Elisa Frisaldi,Manfred Schedlowski Pdf
Due to the recent explosion of placebo research at many levels the Editors believe that a volume on Placebo would be a good addition to the Handbook of Experimental Pharmacology series. In particular, this volume will be built up on a meeting on Placebo which will be held in Tuebingen (Germany) in January 2013, and where the most prominent researchers in this field will present and exchange their ideas. The authors who will be invited to write chapters for this volume will be the very same speakers at this meeting, thus guaranteeing high standard and excellence in the topic that will be treated. The approach of the book is mainly pharmacological, including basic research and clinical trials, and the contents range from different medical conditions and systems, such as pain and the immune system, to different experimental approaches, like in vivo receptor binding and pharmacological/behavioral conditioning. Overall, the volume will give an idea of modern placebo research, of timely concepts in both experimental and clinical pharmacology, as well as of modern methods and tools in neuroscience.
Author : Eric J. Nestler,Steven E. Hyman,Robert C. Malenka Publisher : McGraw Hill Professional Page : 559 pages File Size : 48,7 Mb Release : 2001-04-18 Category : Medical ISBN : 9780071431507
Molecular Basis of Neuropharmacology by Eric J. Nestler,Steven E. Hyman,Robert C. Malenka Pdf
* The most up-to-date and comprehensive coverage of the relationship of brain function and neuroactive chemicals * Authors are world-known leaders in the field * Molecular Neuropharmacology is the hot topic in medicine
Introduction to Neuropsychopharmacology by Leslie Iversen,Susan Iversen,Floyd E. Bloom,Robert H. Roth Pdf
The text ranges from drugs that affect the mood and behavior to hypnotics, narcotics, anticonvulsants, and analgesics, as well as a variety of drugs that affect the autonomic nervous system and psychoactive drugs used for non-medical reasons - nicotine, alcohol, opiates, psychostimulants and cannabis."--BOOK JACKET.
