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Photonanotechnology for Therapeutics and Imaging by Seok Ki Choi Pdf
Photonanotechnology for Therapeutics and Imaging surveys major concepts and recent advances in the use of photonanotechnology with nanomaterials reported in various interdisciplinary fields, including chemistry, materials science, biomedical engineering and biomedicine. This book discusses the impact of this technology on the advancement of therapeutic modalities and imaging methods in cancers, infectious diseases and other serious diseases. Photonanotechnology studies the design principle, application and development of photoactive nanomaterials. It applies light-controlled strategies for the development of nanotherapeutics, imaging agents and diagnostic nanodevices. Provides the latest information on photocontrolled drug delivery systems Details how photoactive nanomaterials are designed to release reactive oxygen species (ROS) for photodynamic therapy (PDT) Explains how photoactive nanomaterials have the ability to induce surface plasmonic heating for photothermal therapeutic (PTT) effects
Imaging in Photodynamic Therapy by Michael R. Hamblin,Yingying Huang Pdf
This book covers the broad field of cellular, molecular, preclinical, and clinical imaging either associated with or combined with photodynamic therapy (PDT). It showcases how this approach is used clinically for cancer, infections, and diseases characterized by unwanted tissue such as atherosclerosis or blindness. Because the photosensitizers are also fluorescent, the book also addresses various imaging systems such as confocal microscopy and small animal imaging systems, and highlights how they have been used to follow and optimize treatment, and to answer important mechanistic questions. Chapters also discuss how imaging has made important contributions to clinical outcomes in skin, bladder, and brain cancers, as well as in the development of theranostic agents for detection and treatment of disease. This book provides a resource for physicians and research scientists in cell biology, microscopy, optics, molecular imaging, oncology, and drug discovery.
Applications of Nanoscience in Photomedicine by Michael R. Hamblin,Pinar Avci Pdf
Nanoscience has become one of the key growth areas in recent years. It can be integrated into imaging and therapy to increase the potential for novel applications in the field of photomedicine. In the past commercial applications of nanoscience have been limited to materials science research only, however, in recent years nanoparticles are rapidly being incorporated into industrial and consumer products. This is mainly due to the expansion of biomedical related research and the burgeoning field of nanomedicine. Applications of Nanoscience in Photomedicine covers a wide range of nanomaterials including nanoparticles used for drug delivery and other emerging fields such as optofluidics, imaging and SERS diagnostics. Introductory chapters are followed by a section largely concerned with imaging, and finally a section on nanoscience-enabled therapeutics. Covers a comprehensive up-to-date information on nanoscience Focuses on the combination of photomedicine with nanotechnology to enhance the diversity of applications Pioneers in the field have written their respective chapters Opens a plethora of possibilities for developing future nanomedicine Easy to understand and yet intensive coverage chapter by chapter
Nanotheranostics for Personalized Medicine by Simona Mura,Patrick Couvreur Pdf
The application of nanotechnology in the biomedical field, known as nanomedicine, has gained much interest in the recent past as a versatile strategy for selective drug delivery and diagnostic purposes. The nanotheranostic approach, which aims to combine both therapeutic and imaging/diagnostic functionalities, is characterized by a strong pluridisciplinarity where the chemistry of materials, bioconjugate chemistry, pharmaceutical technology, drug delivery, imaging, and pharmacology, work together. Nanotheranostics combine simultaneous non-invasive diagnosis and treatment of diseases with the exciting possibility to monitor drug release and distribution in real time; thus offering the opportunity to optimize treatment outcomes in cancer and other severe diseases. Clinical applications of nanotheranostics would enable earlier detection and treatment of diseases, and earlier assessment of the response, thus allowing to identify patients which would potentially respond to therapy and have higher possibilities of a favorable outcome. Nanotheranostics for Personalized Medicine presents an integrated and transdisciplinary description of nanotheranostics. It provides principles of imaging techniques and concrete examples of advances and challenges in the development of nanotheranostics for personalized medicine. This book is written for students (Bachelors to Doctoral level) as well as experienced researchers, in academia or the industry, interested in this emerging concept in the nanomedicine field. Contents:Combining Imaging and Drug Delivery for the Treatment of Severe Diseases (Simona Mura and Patrick Couvreur)Increased Sensitivity for Medical Imaging Using Non-Ionizing Nanomedicine as Contrast Agents (Cyrille Richard, Bich-Thuy Doan and Nathalie Mignet)MRI T2 Weighted Theranostic Nanodevices and Chemotherapy (Sophie Laurent, Luce Vander Elst, Dimitri Stanicki and Robert N Muller)MRI T1 Weighted Theranostic Nanodevices (Lucie Sancey, François Lux, Géraldine Le Duc, Sabin Carme and Olivier Tillement)Optical Imaging and Chemotherapy (Guillaume Bort, Simona Mura and Patrick Couvreur)Plasmonic Nanoparticles-Coated Microbubbles for Theranostic Applications (Mark A Borden, Jacob D Dove and Todd W Murray)Contribution of Nuclear Medicine to Cancer Nanotheranostics (Thomas Lars Andresen, Anncatrine L Petersen, Anders E Hansen and Jonas R Henriksen)Nanotheranostics in Gene Therapy (Madhura Deshpande, Shravan Kumar Sriraman and Vladimir Torchilin)Nanotheranostics in Cardiovascular Diseases (Maya Juenet, Mariana Varna, Cédric Chauvierre and Didier Letourneur)Stimuli-Responsive Nanotheranostics (Basit Yameen, Jun Wu, Critian Vilos, Andrew Whyte David Werstler, Lori Pollit and Omid C Farokhzad)Advancing the Practical Clinical Utility in Personalized Medicine: Capabilities and Lessons Learned for Pharmacology and Pharmaceutics (Ioannis S Vizirianakis, Christina Karavasili, Elsa P Amanatiadou and Dimitrios G Fatouros) Readership: Advanced undergraduates, graduates, as well as experimental researchers in academia or the industry with an interest in this emerging concept in the nanomedicine world. Key Features:This book presents an integrated and transdisciplinary description of an emerging concept in the world of nanomedicine: nanotheranosticsThis work is one of the few dedicated to nanotheranostics and its applicationsWritten by well-recognized experts in academia, this book would offer to the reader a clear overview of the progresses in the field of nanotheranostics and their fundamental contribution to the field of personalized medicineReading this book would open the way to further improvements and to the possible clinical translation of the nanotheranostics concept in the not-too-distant futureKeywords:Bioengineering;Nanomedicine & Nanobiology;Biomedical Engineering;Medical Imaging;Therapy
Nanomedicine for Deep-Tissue High-Resolution Bio-Imaging and Non-Invasive Therapy by Michael Ming-Yuan Wei,Yanbo Pei,Yu Gao Pdf
Dr Ming-Yuan Wei currently holds a pending U.S. Patent Application entitled “Systems and Methods for High-Resolution Imaging”. All other Guest Editors have no other competing interests to declare with regards to the Topic subject.
Author : Professor Fan Zhang Publisher : Royal Society of Chemistry Page : 428 pages File Size : 40,8 Mb Release : 2016 Category : Science ISBN : 9781782623199
Near-infrared Nanomaterials by Professor Fan Zhang Pdf
In the last decade, bioimaging and therapy based on near-infrared (NIR) nanomaterials have played an important role in biotechnology due to their intrinsic advantages when compared with the traditional imaging probe and medicine. NIR nanomaterials allow deeper penetration depth, low detection threshold concentration and better targeted performance. This book systematically summarises the recent progress in the fabrication and application of NIR nanomaterials for biomedical imaging and therapy, and discusses the advantages, challenges and opportunities available. Near-infrared Nanomaterials contains a chapter highlighting the outlook of these materials, detailing novel ideas for the further application of NIR nanomaterials in bioimaging and medicine. Written by leading experts working in the field, this title will have broad appeal to those working in chemistry, materials science, nanotechnology, biology and bioengineering, biomedical science and biophysics.
Nanotechnology for Biomedical Imaging and Diagnostics by Mikhail Y. Berezin Pdf
Nanotechnology for Biomedical Imaging and Diagnostics: FromNanoparticle Design to Clinical Applications reflects upon theincreasing role of nanomaterials in biological and medical imaging,presenting a thorough description of current research as wellas future directions. With contributions from experts innanotechnology and imaging from academia, industry, andhealthcare, this book provides a comprehensive coverage of thefield, ranging from the architectural design of nanomaterials totheir broad imaging applications in medicine. Grouped into three sections, the book: Elucidates all major aspects of nanotechnology andbioimaging Provides comprehensive coverage of the field, ranging from thearchitectural design of nanomaterials to their broad imagingapplications in medicine Written by well-recognized experts in academia, industry, andhealthcare, will be an excellence source of reference With a multidisciplinary approach and a balance of research anddiagnostic topics, this book will appeal to students, scientiests,and healthcare professionals alike
Photophysics and Nanophysics in Therapeutics by Nilesh M. Mahajan,Avneet Saini,Nishikant A. Raut,Sanjay J. Dhoble Pdf
Photophysics and Nanophysics in Therapeutics explores the latest advances and applications of phototherapy and nanotherapy, covering the application of light, radiation, and nanotechnology in therapeutics, along with the fundamental principles of physics in these areas. Consisting of two parts, the book first features a range of chapters covering phototherapeutics, from the fundamentals of photodynamic therapy (PDT) to applications such as cancer treatment and advances in radiotherapy, applied physics in cancer radiotherapy treatment, and the role of carbon ion beam therapy. Other sections cover nanotherapeutics, potential applications and challenges, and nanotherapy for drug delivery to the brain. Final chapters delve into nanotechnology in the diagnosis and treatment of cancers, the role of nanocarriers for HIV treatment, nanoparticles for rheumatoid arthritis treatment, peptide functionalized nanomaterials as microbial sensors, and theranostic nanoagents. Evaluates the latest developments in the fields of phototherapy and nanotherapy Investigates the fundamental physics behind these technologies Explores therapeutic applications across a range of diseases, such as skin disorders, cancer, and neurological conditions Includes case studies that illustrate research in practice Considers challenges and future perspectives
Handbook of Clinical Nanomedicine by Raj Bawa,Gerald F. Audette,Israel Rubinstein Pdf
This handbook (55 chapters) provides a comprehensive roadmap of basic research in nanomedicine as well as clinical applications. However, unlike other texts in nanomedicine, it not only highlights current advances in diagnostics and therapeutics but also explores related issues like nomenclature, historical developments, regulatory aspects, nanosim
Magnetic Nanoparticles in Human Health and Medicine by Costica Caizer,Mahendra Rai Pdf
Magnetic Nanoparticles in Human Health and Medicine Explores the application of magnetic nanoparticles in drug delivery, magnetic resonance imaging, and alternative cancer therapy Magnetic Nanoparticles in Human Health and Medicine addresses recent progress in improving diagnosis by magnetic resonance imaging (MRI) and using non-invasive and non-toxic magnetic nanoparticles for targeted drug delivery and magnetic hyperthermia. Focusing on cancer diagnosis and alternative therapy, the book covers both fundamental principles and advanced theoretical and experimental research on the magnetic properties, biocompatibilization, biofunctionalization, and application of magnetic nanoparticles in nanobiotechnology and nanomedicine. Chapters written by a panel of international specialists in the field of magnetic nanoparticles and their applications in biomedicine cover magnetic hyperthermia (MHT), MRI contrast agents, biomedical imaging, modeling and simulation, nanobiotechnology, toxicity issues, and more. Readers are provided with accurate information on the use of magnetic nanoparticles in diagnosis, drug delivery, and alternative cancer therapeutics—featuring discussion of current problems, proposed solutions, and future research directions. Topics include current applications of magnetic iron oxide nanoparticles in nanomedicine and alternative cancer therapy: drug delivery, magnetic resonance imaging, superparamagnetic hyperthermia as alternative cancer therapy, magnetic hyperthermia in clinical trials, and simulating the physics of magnetic particle heating for cancer therapy. This comprehensive volume: Covers both general research on magnetic nanoparticles in medicine and specific applications in cancer therapeutics Discusses the use of magnetic nanoparticles in alternative cancer therapy by magnetic and superparamagnetic hyperthermia Explores targeted medication delivery using magnetic nanoparticles as a future replacement of conventional techniques Reviews the use of MRI with magnetic nanoparticles to increase the diagnostic accuracy of medical imaging Magnetic Nanoparticles in Human Health and Medicine is a valuable resource for researchers in the fields of nanomagnetism, magnetic nanoparticles, nanobiomaterials, nanobioengineering, biopharmaceuticals nanobiotechnologies, nanomedicine, and biopharmaceuticals, particularly those focused on alternative cancer diagnosis and therapeutics.
Multifunctional Nanoparticles for Drug Delivery Applications by Sonke Svenson,Robert K. Prud'homme Pdf
This book presents the medical challenges that can be reduced or even overcome by recent advances in nanoscale drug delivery. Each chapter highlights recent progress in the design and engineering of select multifunctional nanoparticles.
Organic Nanomaterials for Cancer Phototheranostics by Manzar Abbas,Atia Atiq,Muhammad Ovais,Michael R Hamblin Pdf
Organic Nanomaterials for Cancer Phototheranostics highlights the use of biocompatible building blocks to make nanomaterials that can aid in medical treatment through better diagnostic and antitumor efficacy. It synthesizes the current literature on synthetic strategies and designs based on peptides, proteins, polymers, lipids, and their conjugates, as well as composites and complexes with metals and inorganic components used to form the nanomaterials. Mechanistic approaches, clinical problems, and therapeutic and diagnostics mechanisms are covered in each chapter. Cellular interactions and uptake, pharmacokinetics, biodistribution, drug delivery efficiency, and safety concerns of these types of nanomaterials are discussed, as well. Other topics looked at include photostability, clearance, metabolism, in-vitro and in-vivo mechanisms, therapeutic efficacy, imaging, and toxicology. Outlines fabrication and design strategies of peptides, proteins, polymers, lipids, composites, and complexes with metals and inorganic components Discusses the limitations and challenges of organic nanomaterials in clinical use, including their mechanisms of penetration into cancer cells and tissue, photostability, clearance, and metabolism Covers clinical problems and therapeutic and diagnostics mechanisms
Mechanical Engineering in Biomedical Application by Jay Prakash Srivastava,Drazan Kozak,Vinayak Ranjan,Pankaj Kumar,Ranjan Kumar,Shubham Tayal Pdf
MECHANICAL ENGINEERING IN BIOMEDICAL APPLICATIONS The book explores the latest research and developments related to the interdisciplinary field of biomedical and mechanical engineering offering insights and perspectives on the research, key technologies, and mechanical engineering techniques used in biomedical applications. The book is divided into several sections that cover different aspects of mechanical engineering in biomedical research. The first section focuses on the role of additive manufacturing technologies, rehabilitation in healthcare applications, and artificial recreation of human organs. The section also covers the advances, risks, and challenges of bio 3D printing. The second section presents insight into biomaterials, including their properties, applications, and fabrication techniques. The section also covers the use of powder metallurgy methodology and techniques of biopolymer and bio-ceramic coatings on prosthetic implants. The third section covers biofluid mechanics, including the mechanics of fluid flow within our body, the mechanical aspects of human synovial fluids, and the design of medical devices for fluid flow applications. The section also covers the use of computational modeling to study the blockage of carotid arteries. The final section elaborates on soft robotic manipulation for use in medical sciences. Audience The book provides practical insights and applications for mechanical engineers, biomedical engineers, medical professionals, and researchers working on the design and development of biomedical devices and implants.
Green Plant Extract-Based Synthesis of Multifunctional Nanoparticles and their Biological Activities by Seyed Morteza Naghib,Hamid Reza Garshasbi Pdf
The convergence of nanotechnology with agriculture has transformed farming, while also impacting medicine, biotechnology and environmental science. Plant extracts isolated using new technologies have been used to successfully create new medicines for specific diseases. This book focuses on the eco-friendly synthesis of plant extracts. It provides information about multifunctional nanoparticles, and their versatile applications, including agriculture, food safety, and environmental remediation. The book aims to bridge the gap between nanotechnology and public perception, addressing concerns related to health and environmental impact. Themes within the book span across green synthesis techniques for noble metal nanoparticles, the crucial role of analytical methods in characterizing these "green nanomaterials," and the comprehensive examination of how nanoparticles interact with the human body. Furthermore, the intricate relationships between proteins and nanoparticles is highlighted to explain the physicochemical effects and toxicity of nanomaterials. Readers will learn about sustainable and environmentally friendly approaches for synthesizing nanoparticles, while getting a glimpse of the promising future of nanotechnology in agriculture and beyond.
Metal Oxide Nanocomposite Thin Films for Optoelectronic Device Applications by Rayees Ahmad Zargar Pdf
METAL OXIDE NANOCOMPOSITE THIN FILMS FOR OPTOELECTRONIC DEVICE APPLICATIONS The book provides insight into the fundamental aspects, latest research, synthesis route development, preparation, and future applications of metal oxide nanocomposite thin films. The fabrication of thin film-based materials is important to the future production of safe, efficient, and affordable energy as the devices convert sunlight into electricity. Thin film devices allow excellent interface engineering for high-performance printable solar cells as their structures are highly reliable and stand-alone systems can provide the required megawatts. They have been used as power sources in solar home systems, remote buildings, water pumping, megawatt-scale power plants, satellites, communications, and space vehicles. Metal Oxide Nanocomposite Thin Films for Optoelectronic Device Applications covers the basics of advanced nanometal oxide-based materials, their synthesis, characterization, and applications, and all the updated information on optoelectronics. Topics discussed include the implications of metal oxide thin films, which are critical for device fabrications. It provides updated information on the economic aspect and toxicity, with great focus paid to display applications, and covers some core areas of nanotechnology, which are particularly concerned with optoelectronics and the available technologies. The book concludes with insights into the role of nanotechnology and the physics behind photovoltaics. Audience The book will be an important volume for electronics and electrical engineers, nanotechnologists, materials scientists, inorganic chemists in academic research, and those in industries, exploring the applications of nanoparticles in semiconductors, power electronics, and more.