Physical Virology

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Physical Virology

Author : Urs F. Greber
Publisher : Springer
Page : 235 pages
File Size : 55,7 Mb
Release : 2019-07-17
Category : Medical
ISBN : 9783030147419

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Physical Virology by Urs F. Greber Pdf

This book explores a new challenge in virology: to understand how physical properties of virus particles (virions) and viruses (infected cells) affect the course of an infection. Insights from the emerging field of physical virology will contribute to understanding of the physical nature of viruses and cells, and will open new ways for anti-viral interference. Nine chapters and an editorial written by physicists, chemists, biologists and computational experts describe how virions serve as trail blazers in uncharted territory of cells. The authors outline how particles change in composition as they interact with host cells. Such virus dynamics are crucial for virus entry into cells and infection. It influences the modern concepts of virus-host interactions, viral lineages and evolution. The volume gives numerous up-to-date examples of modern virology and provides a fascinating read for researchers, clinicians and students in the field of infectious diseases.

Physical Virology

Author : Mauricio Comas-Garcia,Sergio Rosales-Mendoza
Publisher : Springer Nature
Page : 348 pages
File Size : 46,8 Mb
Release : 2023-11-01
Category : Medical
ISBN : 9783031368158

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Physical Virology by Mauricio Comas-Garcia,Sergio Rosales-Mendoza Pdf

This book highlights key findings generated during the past years from the main disciplines that constitute Physical Virology, from theoretical physics and simulations to material sciences and vaccines development to structural biology. Each chapter is written by world-class scientists from these areas and is a comprehensive review of where this field stands, as well as the future of Physical Virology. The diversity in the formal training of these scientists results in solving common problems using very distinct approaches, which can produce surprising findings. The multi- and interdisciplinary nature of this field has created a remarkable community that aims at understanding how viruses work and how they can be used in material sciences, chemistry, and biomedicine. Furthermore, the development of Physical Virology has resulted in technological advances that have shaped other fields; for example, it would be impossible to think about the development of Cryo-EM to solve the structure of complex viruses with atomic resolution without the contribution of scientists that created the field of Physical Virology. In the past decade, there has been a great success in the generation of viral systems that can encapsulate drugs, non-viral genetic material, or nanoparticles, as well as in the chemical and genetical modification of virions. Without any doubt in the immediate future, some of these technologies will jump from the bench to the market, creating a revolution in translational and biomedical sciences. The book provides key perspectives for the field, derived from expert ́s opinions.

Emerging Topics in Physical Virology

Author : Peter G. Stockley,Reidun Twarock
Publisher : World Scientific
Page : 333 pages
File Size : 47,5 Mb
Release : 2010
Category : Science
ISBN : 9781848164642

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Emerging Topics in Physical Virology by Peter G. Stockley,Reidun Twarock Pdf

Emerging Topics in Physical Virology is a state-of-the-art account of recent advances in the experimental analysis and modeling of structure, function and dynamics of viruses. It is the first interdisciplinary book that integrates a review of relevant experimental techniques, such as cryo-electron microscopy, atomic force microscopy and mass spectrometry with the latest results on the biophysical and mathematical modeling of viruses. The book comprehensively covers the structure and physical properties of the protein envelopes that encapsulate and hence protect the delicate viral genome, their assembly and disassembly, the organization of the viral genome, infection, evolution, as well as applications of viruses in Biomedical Nanotechnology. It is an essential primer for scientists working in all aspects of virology, including the increasing use of viruses and virus-like particles in bio- and nano-technology. Its review style makes it moreover suitable for non-experts as an introduction into this exciting research area.

Emerging Topics in Physical Virology

Author : Peter G Stockley,Reidun Twarock
Publisher : World Scientific
Page : 332 pages
File Size : 48,6 Mb
Release : 2010-03-17
Category : Science
ISBN : 9781908978226

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Emerging Topics in Physical Virology by Peter G Stockley,Reidun Twarock Pdf

Emerging Topics in Physical Virology is a state-of-the-art account of recent advances in the experimental analysis and modeling of structure, function and dynamics of viruses. It is the first interdisciplinary book that integrates a review of relevant experimental techniques, such as cryo-electron microscopy, atomic force microscopy and mass spectrometry with the latest results on the biophysical and mathematical modeling of viruses. The book comprehensively covers the structure and physical properties of the protein envelopes that encapsulate and hence protect the delicate viral genome, their assembly and disassembly, the organization of the viral genome, infection, evolution, as well as applications of viruses in Biomedical Nanotechnology. It is an essential primer for scientists working in all aspects of virology, including the increasing use of viruses and virus-like particles in bio- and nano-technology. Its review style makes it moreover suitable for non-experts as an introduction into this exciting research area. Contents:Cryo-Electron Microscopy of Viruses (N A Ranson & P G Stockley)What Does It Take to Make a Virus: The Concept of the Viral “Self” (N G A Abrescia et al.)Beyond Quasi-Equivalence: New Insights Into Viral Architecture via Affine Extended Symmetry Groups (T Keef & R Twarock)Mechanical Properties of Viruses (W H Roos & G J L Wuite)Investigating Viral Structure, Function and Dynamics with Mass Spectrometry (E B Monroe & P E Prevelige)An Overview of Capsid Assembly Kinetics (J Z Porterfield & A Zlotnick)Assembly and Disassembly of Deltahedral Viral Shells (A Yu Morozov et al.)What Determines the Size of an RNA Virus? (C M Knobler & W M Gelbart)Physics of Viral Infectivity: Matching Genome Length with Capsid Size (A Evilevitch & M Castelnovo)Topology of Viral DNA (J Arsuaga et al.)The Use of Viruses in Biomedical Nanotechnology (K J Koudelka & M Manchester) Readership: Biologists, biophysicists, chemists, clinicians and mathematical biologists interested in virus structure, function and dynamics. Keywords:Virology;Modeling;Virus Assembly;Virus Structure;Genome Organisation;Cryo-Electron Microscopy;Mass Spectrometry;Viral Evolution

Structure and Physics of Viruses

Author : Mauricio G. Mateu
Publisher : Springer Science & Business Media
Page : 728 pages
File Size : 43,5 Mb
Release : 2013-06-04
Category : Medical
ISBN : 9789400765528

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Structure and Physics of Viruses by Mauricio G. Mateu Pdf

This book contemplates the structure, dynamics and physics of virus particles: From the moment they come into existence by self-assembly from viral components produced in the infected cell, through their extracellular stage, until they recognise and infect a new host cell and cease to exist by losing their physical integrity to start a new infectious cycle. (Bio)physical techniques used to study the structure of virus particles and components, and some applications of structure-based studies of viruses are also contemplated. This book is aimed first at M.Sc. students, Ph.D. students and postdoctoral researchers with a university degree in biology, chemistry, physics or related scientific disciplines who share an interest or are actually working on viruses. We have aimed also at providing an updated account of many important concepts, techniques, studies and applications in structural and physical virology for established scientists working on viruses, irrespective of their physical, chemical or biological background and their field of expertise. We have not attempted to provide a collection of for-experts-only reviews focused mainly on the latest research in specific topics; we have not generally assumed that the reader knows all of the jargon and all but the most recent and advanced results in each topic dealt with in this book. In short, we have attempted to write a book basic enough to be useful to M.Sc and Ph.D. students, as well as advanced and current enough to be useful to senior scientists with an interest in Structural and/or Physical Virology.

Essential Human Virology

Author : Jennifer Louten
Publisher : Academic Press
Page : 412 pages
File Size : 42,6 Mb
Release : 2022-05-28
Category : Science
ISBN : 9780323914925

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Essential Human Virology by Jennifer Louten Pdf

Essential Human Virology, Second Edition focuses on the structure and classification of viruses, virus transmission and virus replication strategies based upon type of viral nucleic acid. Several chapters focus on notable and recognizable viruses and the diseases caused by them, including influenza, HIV, hepatitis viruses, poliovirus, herpesviruses and emerging and dangerous viruses. Additionally, how viruses cause disease (pathogenesis) is highlighted, along with discussions on immune response to viruses, vaccines, anti-viral drugs, gene therapy, the beneficial uses of viruses, research laboratory assays and viral diagnosis assays. Fully revised and updated with new chapters on coronaviruses, nonliving infectious agents, and notable non-human viruses, the book provides students with a solid foundation in virology. Focuses on human diseases and the cellular pathology that viruses cause Highlights current and cutting-edge technology and associated issues Presents real case studies and current news highlights in each chapter Features dynamic illustrations, chapter assessment questions, key terms, and a summary of concepts, as well as an instructor website with lecture slides, a test bank and recommended activities Updated and revised, with new chapters on coronaviruses, nonliving infectious agents, and notable non-human viruses

General Virology

Author : F. M. Burnet,W. M. Stanley
Publisher : Academic Press
Page : 628 pages
File Size : 42,6 Mb
Release : 2013-09-24
Category : Science
ISBN : 9781483257662

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General Virology by F. M. Burnet,W. M. Stanley Pdf

The Viruses, Volume 1: General Virology focuses on physical and chemical approaches to virology, including cellular organization, inactivation of viruses, and plant viruses. The selection first offers information on the problems of virology and the structural and chemical architecture of host cells with special reference to the synthesis of polymers. Discussions focus on cellular organization, patterns of polymer synthesis, problems of polymer duplication, and biochemical mechanisms of enzyme and protein synthesis. The book also takes a look at the physical properties of infective particles and quantitative relationships between virus particles and their functional activity. The publication ponders on the inactivation of viruses; chemical basis of the infectivity of tobacco mosaic virus and other plant viruses; and comparative chemistry of infective virus particles and their functional activity. The book also elaborates on comparative chemistry of infective virus particles and of other virus-specific products and biochemistry of insect viruses. The selection is a dependable source of information for readers interested in virology.

Structural Virology

Author : Mavis Agbandje-McKenna,Robert McKenna
Publisher : Royal Society of Chemistry
Page : 388 pages
File Size : 51,6 Mb
Release : 2010-11-11
Category : Medical
ISBN : 9781849732239

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Structural Virology by Mavis Agbandje-McKenna,Robert McKenna Pdf

Over the last ten years, much effort has been devoted to improving the biophysical techniques used in the study of viruses. This has resulted in the visualization of these large macromolecular assemblages at atomic level, thus providing the platform for functional interpretation and therapeutic design. Structural Virology covers a wide range of topics and is split into three sections. The first discusses the vast biophysical methodologies used in structural virology, including sample production and purification, confocal microscopy, mass spectrometry, negative-stain and cryo-electron microscopy, X-ray crystallography and nuclear magnetic resonance spectroscopy. The second discusses the role of virus capsid protein structures in determining the functional roles required for receptor recognition, cellular entry, capsid assembly, genome packaging and mechanisms of host immune system evasion. The last section discusses therapeutic strategies based on virus protein structures, including the design of antiviral drugs and the development of viral capsids as vehicles for foreign gene delivery. Each topic covered will begin with a review of the current literature followed by a more detailed discussion of experimental procedures, a step in the viral life cycle, or strategies for therapeutic development. With contributions from experts in the field of structural biology and virology this exceptional monograph will appeal to biomedical scientists involved in basic and /or applied research on viruses. It also provides up-to-date reference material for students entering the field of structural virology as well as scientists already familiar with the area.

Comparative Virology

Author : Karl Maramorosch,Edouard Kurstak
Publisher : Academic Press
Page : 600 pages
File Size : 52,6 Mb
Release : 2014-06-28
Category : Science
ISBN : 9781483269696

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Comparative Virology by Karl Maramorosch,Edouard Kurstak Pdf

Comparative Virology provides an integrated comparison of viruses, based on their chemical and morphological characteristics. These descriptions will not only give the reader a background but also a detailed analysis of the various groups. In some instances the groups are still host related, as in the case of bacteriophages and polyhedral insect viruses. In others, for instance in pox viruses, the group comprises viruses of vertebrates and invertebrates. The hosts of the bacilliform Rhabdovirales range from man and other warm-blooded vertebrates through invertebrate animals to plants. A special chapter is devoted to viruses devoid of protein—a group that is of great interest and that has only recently been recognized. Since there is historical and practical interest in écologie groupings, such as arboviruses and oncogenic viruses, chapters on such groups have also been included. The book opens with a discussion on the classification of viruses. Chapters dealing with DNA viruses and RNA viruses follow, and the ecologically and disease-oriented groups complete the volume. It is hoped that ""Comparative Virology"" will help bring unity to the science of virology through the comparative approach that is not dependent on virus-host interactions. The combined efforts of eminent contributors to discuss and evaluate new information will hopefully benefit all who are interested in virology

Fields Virology: RNA Viruses

Author : Peter M. Howley,David M. Knipe,Sean Whelan,Eric O. Freed
Publisher : Lippincott Williams & Wilkins
Page : 2471 pages
File Size : 49,8 Mb
Release : 2022-06-09
Category : Medical
ISBN : 9781975112615

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Fields Virology: RNA Viruses by Peter M. Howley,David M. Knipe,Sean Whelan,Eric O. Freed Pdf

Now in four convenient volumes, Field’s Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families. This volume of Field’s Virology: RNA Viruses, Seventh Edition covers the latest information on RNA viruses, how they cause disease, how they can cause epidemics and pandemics, new therapeutics and vaccine approaches, as provided in new or extensively revised chapters that reflect these advances in this dynamic field. Bundled with the eBook, which will be updated regularly as new information about each virus is available, this text serves as the authoritative, up-to-date reference book for virologists, infectious disease specialists, microbiologists, and physicians, as well as medical students pursuing a career in infectious diseases.

Fundamentals of Molecular Virology

Author : Nicholas H. Acheson
Publisher : Wiley Global Education
Page : 528 pages
File Size : 42,6 Mb
Release : 2012-04-13
Category : Science
ISBN : 9781118213827

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Fundamentals of Molecular Virology by Nicholas H. Acheson Pdf

Designed for students learning about viruses for the first time at the undergraduate or graduate level, Fundamentals of Molecular Virology is presented in a style which relates to today's students and professors. This book is also a valuable, up-to-date source of information for graduate students, postdoctoral fellows and research scientists working with viruses. Chapters contributed by prominent virologists were edited to conform to a clear and accessible style. The text provides a thorough presentation of basic and contemporary concepts in virology for a student's first exposure to the field.

Fields Virology: Emerging Viruses

Author : Peter M. Howley,David M. Knipe
Publisher : Lippincott Williams & Wilkins
Page : 2597 pages
File Size : 55,9 Mb
Release : 2020-02-11
Category : Medical
ISBN : 9781975112554

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Fields Virology: Emerging Viruses by Peter M. Howley,David M. Knipe Pdf

Now in four convenient volumes, Field’s Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families. This volume of Field’s Virology: Emerging Viruses, 7th Edition covers recent changes in emerging viruses, providing new or extensively revised chapters that reflect these advances in this dynamic field.

Introduction to Virology

Author : Paul Mahoney
Publisher : Unknown
Page : 251 pages
File Size : 53,5 Mb
Release : 2018-02-08
Category : Medical
ISBN : 1641160063

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Introduction to Virology by Paul Mahoney Pdf

The study of viruses is known as virology. It focuses on the structure, evolution and behavior of viruses. Studying them is vital, as they cause various infectious diseases like dengue, yellow fever, smallpox, etc. The classification of viruses is done on the basis of the host that they infect, like fungal viruses, bacteriophages, animal viruses, etc. This book attempts to assist those with a goal of delving into the field of virology. Coherent flow of topics, student-friendly language and extensive use of examples make this textbook an invaluable source of knowledge.

Encyclopedia of Virology

Author : Anonim
Publisher : Academic Press
Page : 4109 pages
File Size : 46,6 Mb
Release : 2021-02-24
Category : Science
ISBN : 9780128145166

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Encyclopedia of Virology by Anonim Pdf

Encyclopedia of Virology, Fourth Edition, Five Volume Set builds on the solid foundation laid by the previous editions, expanding its reach with new and timely topics. In five volumes, the work provides comprehensive coverage of the whole virosphere, making this a unique resource. Content explores viruses present in the environment and the pathogenic viruses of humans, animals, plants and microorganisms. Key areas and concepts concerning virus classification, structure, epidemiology, pathogenesis, diagnosis, treatment and prevention are discussed, guiding the reader through chapters that are presented at an accessible level, and include further readings for those needing more specific information. More than ever now, with the Covid19 pandemic, we are seeing the huge impact viruses have on our life and society. This encyclopedia is a must-have resource for scientists and practitioners, and a great source of information for the wider public. Offers students and researchers a one-stop shop for information on virology not easily available elsewhere Fills a critical gap of information in a field that has seen significant progress in recent years Authored and edited by recognized experts in the field, with a range of different expertise, thus ensuring a high-quality standard

Principles of Molecular Virology

Author : Alan Cann
Publisher : Elsevier
Page : 340 pages
File Size : 51,8 Mb
Release : 2005-07-26
Category : Medical
ISBN : 0120887894

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Principles of Molecular Virology by Alan Cann Pdf

"Principles of Molecular Virology, Fourth Edition" provides an essential introduction to modern virology in a clear and concise manner. It is a highly enjoyable and readable text with numerous illustrations that enhance the reader's understanding of important principles. It contains new material on virus structure, virus evolution, zoonoses, bushmeat, SARS and bioterrorism. The standard version includes a CD-ROM with Flash animations, virtual interactive tutorials and experiments, self-assessment questions, useful online resources, along with the glossary, classification of subcellular infectious agents and history of virology.