Pituitary Microadenomas

Author : Kamal Thapar,Kalman Kovacs,Bernd Scheithauer,Ricardo V. Lloyd
Publisher : Springer Science & Business Media
Page : 479 pages
File Size : 43,9 Mb
Release : 2000-11-09
Category : Medical
ISBN : 9781592592173

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Diagnosis and Management of Pituitary Tumors by Kamal Thapar,Kalman Kovacs,Bernd Scheithauer,Ricardo V. Lloyd Pdf

Eminent clinicians and specialists thoroughly review in great detail every aspect of pituitary tumors. The topics covered include prolactinomas, somatotroph adenomas, corticotroph adenomas, thyrotroph adenomas, nonfunctioning tumors, pituitary tumors, invasive adenomas, and pituitary carcinomas, as well as lesions, exclusive of pituitary adenomas, that occur in the sellar region. Also discussed are the new methods in endocrine diagnosis, high resolution imaging, receptor-mediated pharmacotherapy, microsurgical techniques, improved methods of radiation delivery, and the development of a precise and physiologically meaningful classification of pituitary tumors. Much-needed and brilliantly multidisciplinary, Diagnosis and Management of Pituitary Tumors offers all those dealing with pituitary cancer patients today's most comprehensive guide to diagnosis and treatment, one whose coordinated treatment strategies have sharply improved long-term survival rates for many patients.

Author : G. Faglia,M. Giovanelli,Robert Meredith MacLeod
Publisher : Unknown
Page : 588 pages
File Size : 49,5 Mb
Release : 1980
Category : Medical
ISBN : UOM:39015000794241

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Pituitary Microadenomas by G. Faglia,M. Giovanelli,Robert Meredith MacLeod Pdf

Author : Gianluca Tamagno,Manuel D. Gahete
Publisher : Springer Nature
Page : 340 pages
File Size : 43,5 Mb
Release : 2022-01-31
Category : Medical
ISBN : 9783030904753

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Pituitary Adenomas by Gianluca Tamagno,Manuel D. Gahete Pdf

Stemming from the ENEA Young Researcher Committee, this didactical book comprehensively discusses all aspects of pituitary adenomas, particularly the practical aspects arising in everyday clinical practice. Offering valuable tips, it serves as a guide for young trainee endocrinologists facing their first cases of pituitary adenomas. It also includes illustrative clinical cases of acromegaly, prolactinomas, Cushing’s disease, and TSHomas. In addition, a Questions & Answers section is available online. The mix of fresh enthusiasm and well-established expertise in the field provided by the editors and the committee they belong to make the book both solid and innovative, with an appropriate balance between the traditional knowledge and the most exciting innovations from recent or ongoing research. Written and edited by young researchers active in the field of neuroendocrinology, it is a valuable resource for anyone working or interested in the field.

Author : Cristiana Tanase,Irina Ogrezeanu,Corin Badiu
Publisher : Elsevier
Page : 129 pages
File Size : 48,9 Mb
Release : 2011-11-16
Category : Medical
ISBN : 9780124158306

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Molecular Pathology of Pituitary Adenomas by Cristiana Tanase,Irina Ogrezeanu,Corin Badiu Pdf

The pituitary gland is an important one since it controls several of the other hormone glands, such as the thyroid and adrenals. A pituitary adenoma is an abnormal growth or tumor in this gland, and they are the subject of very active clinical and pathological research. This book examines the latest developments in this field and discusses the most important molecules implicated in apoptosis, angiogenesis and signal transduction. A good understanding of these processes is needed to identify the best therapies. Facilitates the understanding of the processes involved and how they are translated into therapy Illustrations are used to explain the complex mechanisms involved

Author : Shlomo Melmed
Publisher : Academic Press
Page : 744 pages
File Size : 47,7 Mb
Release : 2010-12-09
Category : Medical
ISBN : 0123809274

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The Pituitary by Shlomo Melmed Pdf

The pituitary, albeit a small gland, is known as the "master gland" of the endocrine system and contributes to a wide spectrum of disorders, diseases, and syndromes. Since the publication of the second edition of The Pituitary, in 2002, there have been major advances in the molecular biology research of pituitary hormone production and action and there is now a better understanding of the pathogenesis of pituitary tumors and clinical syndromes resulting in perturbation of pituitary function. There have also been major advances in the clinical management of pituitary disorders. Medical researchers and practitioners now better understand the morbidity and mortality associated with pituitary hormone hyposecretion and hypersecretion. Newly developed drugs, and improved methods of delivering established drugs, are allowing better medical management of acromegaly and prolactinoma. These developments have improved the worldwide consensus around the definition of a "cure" for pituitary disease, especially hormone hypersecretion, and hence will improve the success or lack of success of various forms of therapy. It is therefore time for a new edition of The Pituitary. The third edition will continue to be divided into sections that summarize normal hypothalamic-pituitary development and function, hypothalamic-pituitary failure, and pituitary tumors; additional sections will describe pituitary disease in systemic disorders and diagnostic procedures, including imaging, assessment of the eyes, and biochemical testing. The first chapter will be completely new – placing a much greater emphasis on physiology and pathogenesis. Two new chapters will be added on the Radiation and Non-surgical Management of the Pituitary and Other Pituitary Lesions. Other chapters will be completely updated and many new author teams will be invited. The second edition published in 2002 and there have been incredible changes in both the research and clinical aspects of the pituitary over the past 8 years – from new advances in growth hormones to pituitary tumor therapy. Presents a comprehensive, translational source of information about the pituitary in one reference work Pituitary experts (from all areas of research and practice) take readers from the bench research (cellular and molecular mechanism), through genomic and proteomic analysis, all the way to clinical analysis (histopathology and imaging) and new therapeutic approaches Clear presentation by endocrine researchers of the cellular and molecular mechanisms underlying pituitary hormones and growth factors as well as new techniques used in detecting lesions (within the organ) and other systemic disorders Clear presentation by endocrinologists and neuroendocrine surgeons of how imaging, assessment of the eyes, and biochemical testing can lead to new therapeutic approaches

Author : G. Faglia,M. Giovanelli,Robert Meredith MacLeod
Publisher : Unknown
Page : 590 pages
File Size : 44,8 Mb
Release : 1980
Category : Adenoma
ISBN : UCAL:B4425658

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Pituitary Microadenomas by G. Faglia,M. Giovanelli,Robert Meredith MacLeod Pdf

Author : Jürgen Honegger,Martin Reincke,Stephan Petersenn
Publisher : Elsevier
Page : 722 pages
File Size : 49,7 Mb
Release : 2021-04-14
Category : Medical
ISBN : 9780128199497

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Pituitary Tumors by Jürgen Honegger,Martin Reincke,Stephan Petersenn Pdf

Pituitary Tumors: A Comprehensive and Interdisciplinary Approach provides the latest information on preclinical issues, diagnostic procedures, treatment options and post-treatment care for patients with pituitary tumors. The book includes basic and advanced knowledge for a broad audience, including physicians, endocrinologists, neurosurgeons, neuro-radiologists, neuro-ophthalmologists, neuro-pathologists, oncologists, radiotherapists and researchers who are investigating pituitary tumors. Readers will find the latest research surrounding progress on uncoding the molecular mechanisms involved in tumor genesis. In addition, standard treatment modalities, including surgery, medical treatment and radiosurgery are explored. Provides state-of-the-art knowledge from experts who cover all specialties involved in the field of pituitary tumors Offers a comprehensive presentation of related issues to pituitary tumors Delivers a complete reference book for a broad audience, providing both basic and advanced knowledge

Author : Kalmon D. Post
Publisher : Springer Science & Business Media
Page : 515 pages
File Size : 53,6 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9781468436686

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The Pituitary Adenoma by Kalmon D. Post Pdf

The idea for this book developed as an outcome of a multidisciplinary sym posium entitled "Pituitary Adenoma Update" that was held at Tufts-New En gland Medical Center in April 1977. The purpose of that symposium was to put together our current knowledge of the cause of pituitary tumors and discuss the diagnostic evaluation and management that was now appropriate, in light of the rapid advances that had taken place so recently in this area. Those of our colleagues who had presented papers at the symposium, as well as a number of others, were invited to contribute to this volume, which should serve as a presentation of the "state of the art" on all aspects of pitu itary tumors. We felt that such a book would be of value to endocrinologists, neurosurgeons, neuroradiologists, and pathologists who are involved in the investigation or care of patients with pituitary disorders. For a number of reasons, a review of pituitary adenomas seems particu larly timely. Rapid advances have taken place coincidentally in the fields of neurosurgery, neuroendocrinology, neuroradiology, neuropathology, and neuropharmacology. Seven major developments in these areas have occurred independently and almost simultaneously that have virtually revolutionized our approach to pituitary adenomas.

Author : Gabriel Zada,M. Beatriz S. Lopes,Srinivasan Mukundan Jr.,Edward R. Laws Jr.
Publisher : Springer
Page : 546 pages
File Size : 43,8 Mb
Release : 2015-10-27
Category : Medical
ISBN : 9783319228556

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Atlas of Sellar and Parasellar Lesions by Gabriel Zada,M. Beatriz S. Lopes,Srinivasan Mukundan Jr.,Edward R. Laws Jr. Pdf

This book presents, in a stepwise and interactive fashion, approximately 75 cases that reflect the wide spectrum of pathology encountered in this region. Each case description commences with a concise clinical scenario. High-quality radiologic, laboratory, and histopathologic images depicting the differentiating features of the lesion subtype in question are then presented, and key operative and clinical management pearls are briefly reviewed. The interdisciplinary nature of this easy-to-use color atlas and textbook reflects the fact that the management of patients with sellar and parasellar lesions is itself often interdisciplinary. The format is unique in that no similar interdisciplinary book is available on lesions of this region of the brain. Atlas of Sellar and Parasellar Lesions: Clinical, Imaging, and Pathologic Correlations is of great value for practitioners and trainees in a range of medical specialties, including radiology, neurology, endocriniology, pathology, oncology, radiation oncology, and neurosurgery.

Author : Jean-François Bonneville,Fabrice Bonneville,Françoise Cattin,Sonia Nagi
Publisher : Springer
Page : 397 pages
File Size : 45,8 Mb
Release : 2016-04-26
Category : Medical
ISBN : 9783319290430

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MRI of the Pituitary Gland by Jean-François Bonneville,Fabrice Bonneville,Françoise Cattin,Sonia Nagi Pdf

This clinically oriented book will familiarize the reader with all aspects of the diagnosis of tumors and other disorders of the pituitary gland by means of magnetic resonance imaging (MRI). The coverage includes acromegaly, Cushing’s disease, Rathke cleft cysts, prolactinomas, incidentalomas, nonsecreting adenomas, other lesions of the sellar area, hypophysitis, and central diabetes insipidus. Normal radiologic anatomy and the numerous normal variants are described, and guidance is also provided on difficulties, artifacts, and other pitfalls. The book combines concise text and high-quality images with a question and answer format geared toward the needs of the practitioner. MRI is today considered the cornerstone in the diagnosis of diseases of the hypophyseal-hypothalamic region but the relatively small size of the pituitary gland, its deep location, the many normal anatomic variants, and the often tiny size of lesions can hinder precise evaluation of the anatomic structures and particularly the pituitary gland itself. Radiologists and endocrinologists will find MRI of the Pituitary Gland to be full of helpful information on this essential examination, and the book will also be of interest to internists and neurosurgeons.

Author : Enrico de Divitiis,Paolo Cappabianca
Publisher : Springer Science & Business Media
Page : 203 pages
File Size : 42,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783709160848

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Endoscopic Endonasal Transsphenoidal Surgery by Enrico de Divitiis,Paolo Cappabianca Pdf

Currently, surgical management provides the definitive treatment of choice for most pituitary adenomas, craniopharyngiomas and meningiomas of the sellar region. The elegant minimally invasive transnasal endoscopic approach to the sella turcica and the anterior skull base has added a new dimension of versatility to pituitary surgery and can be adapted to many lesions in the region. In this multi-author book with numerous color illustrations the main aspects of the endonasal endoscopic approach to the skull base are presented, starting with a clear description of the endoscopic anatomy, the panoramic view afforded by the endoscope and the development of effective instruments and adjuncts. After the diagnostic studies, the strictly surgical features are considered in detail. The standard technique is described and particular aspects are treated, including the new extended approaches to the cavernous sinus, spheno-ethmoid planum and clival regions.

Author : Sylvia L. Asa
Publisher : American Registry of Pathology
Page : 228 pages
File Size : 51,6 Mb
Release : 1998
Category : Medical
ISBN : UOM:39015043116402

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Tumors of the Pituitary Gland by Sylvia L. Asa Pdf

Author : Constantine A. Stratakis
Publisher : Academic Press
Page : 312 pages
File Size : 50,9 Mb
Release : 2021-06-01
Category : Medical
ISBN : 9780128145388

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Gigantism and Acromegaly by Constantine A. Stratakis Pdf

Gigantism and Acromegaly brings together pituitary experts, taking readers from bench research, to genetic analysis, clinical analysis, and new therapeutic approaches. This book serves as a reference for growth hormone over-secretion and its diagnosis and treatment for endocrinologists, pediatricians, internists, and neurosurgeons, and for geneticists. Pharmaceutical companies may use it as a reference for drug development and research. Students, residents and fellows in medicine and endocrinology and genetics will also find it valuable as it provides a single up-to-date review of the molecular biology of gigantism and acromegaly as well as recommended approaches to evaluation and management. Acromegaly is a rare pituitary disorder that slowly changes its adult victim’s appearance over time: larger hands and feet, bigger jaw, forehead, nose, and lips. Generally, a benign pituitary tumor is the cause and symptoms of acromegaly can vary from patient to patient, making a diagnosis difficult and prolonging suffering for years. Early detection is key in the management of acromegaly as the pathologic effects of increased growth hormone (GH) production are progressive and can be life-threatening as the result of associated cardiovascular, cerebrovascular, and respiratory disorders and malignancies. Accessible, up-to-date overview of the characteristics, state-of-the-art diagnostic procedures, and management of acromegaly and gigantism Provides a unique compendium of endocrinology, genetics, clinical diagnosis and therapeutics Contains contributions from internationally known experts who have treated patients with acromegaly and gigantism

Author : Adekunle M. Adesina,Tarik Tihan,Christine E. Fuller,Tina Young Poussaint
Publisher : Springer
Page : 349 pages
File Size : 48,7 Mb
Release : 2016-10-03
Category : Medical
ISBN : 9783319334325

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Atlas of Pediatric Brain Tumors by Adekunle M. Adesina,Tarik Tihan,Christine E. Fuller,Tina Young Poussaint Pdf

This text was created to fill a void in the practice of pediatric neuropathology. It is a practical and well-illustrated book representing a collection of interesting, common and unusual tumors for a diagnostic exercise by the reader. The wide reception of the first edition by the pathology community is testament to its relevance and utility in the pathologic diagnosis of pediatric brain tumors. This edition covers topics ranging from neuroimaging, the use of crush and touch preps during intraoperative consultation, classic histological features of pediatric brain tumors, tumor variants, and a miscellaneous group of challenging tumors. Chapters consist of essential diagnostic information and features highlighting recognized variants and their differential diagnoses. A section on molecular pathology and electron microscopy is also included for each tumor category, along with a list of classic reviews and innovative articles on each of the tumor entities as suggested reading at the end of each chapter. Atlas of Pediatric Brain Tumors, Second Edition represents the state of the art in pediatric neuropathology with easy utility beside the microscope.

Author : Edward R. Laws,Jason P. Sheehan
Publisher : Karger Medical and Scientific Publishers
Page : 297 pages
File Size : 54,8 Mb
Release : 2006-01-01
Category : Medical
ISBN : 9783805580519

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Pituitary Surgery by Edward R. Laws,Jason P. Sheehan Pdf

The management of pituitary adenomas and other sellar tumors is one of the most difficult tasks for neurosurgeons and endocrinologists. Optimal treatment requires a multidisciplinary approach; neurological, ophthalmological, and endocrinological tests are all required. Fortunately, the past decade has seen rapid improvements in the management of patients with pituitary adenomas and other sellar tumors. Transsphenoidal surgery has gone from being an innovative approach to pituitary adenomas to having become the standard procedure for a whole variety of sellar and para-sellar lesions. The authors contributing to this book expertly detail the state-of-the-art treatment of patients with pituitary adenomas, covering operative approaches, peri-operative management, surgical pathology as well as the newer extensions such as image guidance and endoscopy. They also identify the complementary roles of radiosurgery and transcranial surgery in the approach to sellar and suprasellar tumors. In addition the text gives a glimpse at what the future may hold for the treatment of such tumors. The present volume of Frontiers of Hormone Research will be of great value for endocrinologists, neurosurgeons, neuropathologists, neuro-ophthalmologists, and otolaryngologists in the treatment of patients with pituitary adenomas.